Health — Alzheimers — November 23rd, 2025

Boosting one protein helps the brain protect itself from Alzheimer’s
Researchers discovered that raising the protein Sox9 can help the brain’s astrocytes clear out toxic plaque buildup linked to Alzheimer’s. In mouse models that already showed memory problems, activating these cells improved cognitive performance. The treatment also reduced plaque levels over time. The work points toward a natural, cell-based way to slow Alzheimer’s decline.
November 23, 2025 — Source

Health — Alzheimers — November 21st, 2025

Arginine supplementation curbs Alzheimer's disease pathology in animal models
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid &beta (A&beta) have recently been developed, their clinical effectiveness remains limited. These treatments can be costly and cause immune-related side effects, highlighting the need for safer, affordable, and widely accessible approaches that can slow the progression of AD.
November 21, 2025 — Source

Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer's
Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function. The mechanism involves recruiting brain cells known as astrocytes, star shaped cells in the brain, to remove the toxic amyloid plaques that build up in many Alzheimer's disease brains. Increasing the production of Sox9, a key protein that regulates astrocyte functions during aging, triggered the astrocytes' ability to remove amyloid plaques.
November 21, 2025 — Source or Source

Chris Hemsworth and dad fight Alzheimer's with a trip down memory lane
Ars chats with director Tom Barbor-Might about new National Geographic documentary A Road Trip to Remember.
November 21, 2025 — Source or Watch Video

How the cheese-noodle principle could help counter Alzheimer's
Researchers at the Paul Scherrer Institute PSI have clarified how spermine—a small molecule that regulates many processes in the body's cells—can guard against diseases such as Alzheimer's and Parkinson's: It renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together. This discovery could help combat such diseases.
November 21, 2025 — Source

Oral arginine reduces amyloid buildup in Alzheimer's models
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid &beta (A&beta) have recently been developed, their clinical effectiveness remains limited. These treatments can be costly and cause immune-related side effects, highlighting the need for safer, affordable, and widely accessible approaches that can slow the progression of AD.
November 21, 2025 — Source

Study clarifies how spermine can guard against Alzheimer's and Parkinson's
Researchers at the Paul Scherrer Institute PSI have clarified how spermine - a small molecule that regulates many processes in the body's cells - can guard against diseases such as Alzheimer's and Parkinson's: it renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together. This discovery could help combat such diseases.
November 21, 2025 — Source

Health — Alzheimers — November 20th, 2025

Exercising in mid and later life can reduce dementia risk, new study suggests
For years, scientists have known that moving our bodies can sharpen our minds. Physical activity boosts blood flow to the brain, enhances neuroplasticity and reduces chronic inflammation. These processes are believed to protect against cognitive decline, including dementia.
November 20, 2025 — Source

Staying connected: How social ties can protect aging brains
"Social frailty" is a major dementia risk. A UNSW researcher is changing how to spot and treat it early.
November 20, 2025 — Source

Health — Alzheimers — November 13th, 2025

How income may shape risk of dementia
People with lower incomes and people from racial and ethnic historically underrepresented groups in clinical studies are more likely to have modifiable risk factors for dementia, factors that could be changed to lower their risk, according to a study published in Neurology.
November 13, 2025 — Source

Health — Alzheimers — November 8th, 2025

Scientists find brain cells that could stop Alzheimer's
Researchers have identified special immune cells in the brain that help slow Alzheimer's. These microglia work to reduce inflammation and block the spread of harmful proteins. They appear to protect memory and brain health, offering a promising new direction for therapy.
November 8, 2025 — Source

Health — Alzheimers — November 7th, 2025

Why Alzheimer's patients forget loved ones
UVA's Harald Sontheimer, graduate student Lata Chaunsali and their colleagues found that when protective structures around brain cells break down, people may lose the ability to recognize loved ones. In lab studies, keeping these structures intact helped mice remember one another.
November 7, 2025 — Source

Health — Alzheimers — November 6th, 2025

5,000 steps a day may slow Alzheimer's-related brain changes
New research reveals that even modest daily walking can slow the buildup of Alzheimer's-linked proteins and delay cognitive decline, giving older adults a realistic path to protect their memory and independence.
November 6, 2025 — Source

Health — Alzheimers — November 5th, 2025

Alzheimer's can hijack communication between brain and fat tissue, potentially worsening metabolic health
Alzheimer's disease disrupts communication between nerves and blood vessels in fat tissue, impairing autonomic regulation of metabolism. This interference may worsen metabolic and cardiovascular conditions such as diabetes, heart disease, and stroke, providing insight into the broader health complications observed in individuals with Alzheimer's.
November 5, 2025 — Source

Nanobodies from camels and llamas offer promise for treating schizophrenia and Alzheimer's disease
Nanobodies—tiny proteins derived from animals in the camelid family including camels, llamas, and alpacas—could be useful in treating brain disorders like schizophrenia and Alzheimer's disease.
November 5, 2025 — Source

Protective microglia subtype offers potential therapeutic pathway in Alzheimer's disease
A distinct microglia subtype characterized by reduced PU.1 and co-expression of CD28 limits neuroinflammation and slows amyloid and tau pathology in Alzheimer's disease. Lowering PU.1 enhances protective microglial functions, while loss of CD28 increases inflammation and plaque growth. These findings highlight the PU.1--CD28 axis as a potential target for microglia-based immunotherapies.
November 5, 2025 — Source

Researchers discover why living in a deprived neighborhood may raise dementia risk
Cambridge researchers have discovered why living in a disadvantaged neighborhood may be linked to an increase in an individual's risk of dementia.
November 5, 2025 — Source

Shared synaptic mechanism for Alzheimer's and Parkinson's disease unlocks new treatment possibilities
A shared molecular cascade in Alzheimer's and Parkinson's diseases disrupts synaptic vesicle recycling by causing excess microtubule formation, which sequesters dynamin and impairs vesicle retrieval. This synaptic dysfunction underlies both memory and motor symptoms, highlighting common therapeutic targets such as protein accumulation, microtubule overproduction, and microtubule-dynamin interaction.
November 5, 2025 — Source

Study sheds light on how Alzheimer's disease may contribute to larger health issues
A recent study from Houston Methodist sheds light on how Alzheimer's disease may contribute to larger health issues by hijacking the body's ability to regulate its metabolism. Researchers have discovered that along with the negative effects an Alzheimer's diagnosis brings, the disease can also sabotage messages between nerves and blood vessels in fat tissue, which can worsen heart and metabolic conditions such as stroke, heart disease and diabetes.
November 5, 2025 — Source

Health — Alzheimers — October 31st, 2025

Predicting the risk of heart disease and dementia in older adults: Q&A
More than 70% of people over 70 years old will one day develop cardiovascular disease, highlighting the need for effective diagnosis, treatment, and care for this population.
October 31, 2025 — Source

Health — Alzheimers — October 30th, 2025

How guided cognitive training may improve brain performance
The University of Texas at Arlington is expanding its research on brain health, focusing on how people navigate their surroundings and remember information. The findings could lead to improved strategies for enhancing brain function and slowing cognitive decline in conditions such as Alzheimer's disease.
October 30, 2025 — Source

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level
Chronic traumatic encephalopathy (CTE) -- most often found in athletes playing contact sports -- is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain. New research published today in Science finds even more commonalities between the two at the genetic level, showing CTE (like AD) is linked to damage to the genome and not just caused by repeated head impact (RHI).
October 30, 2025 — Source

Health — Alzheimers — October 24th, 2025

Popular cholesterol drugs may help prevent dementia
A massive genetic study found that naturally lower cholesterol is linked to a dramatically reduced risk of dementia. The research simulated the effects of cholesterol-lowering drugs and showed up to an 80% lower risk for certain genetic profiles. Scientists believe high cholesterol may contribute to dementia through atherosclerosis and small blood clots. Long-term trials could confirm whether medications can replicate this protective effect.
October 24, 2025 — Source

Health — Alzheimers — October 20th, 2025

Helpline support eases stress for dementia caregivers
Telephone-based helpline consultations significantly improve dementia caregivers' ability to manage stress and negative emotions. Caregivers with lower initial emotional management are more likely to seek multiple consultations. Early screening can help identify those needing additional support. The most common caregiver needs include service information, communication strategies, and emotional support.
October 20, 2025 — Source

Social and environmental inequality linked to risk of Alzheimer's
Where you live could shape how your brain ages, with neighborhood inequality and environmental stressors leaving measurable biological traces linked to Alzheimer's disease.
October 20, 2025 — Source

Health — Alzheimers — October 15th, 2025

Cellular railroad switches: How the brain routes supplies to build memories
Rab4 and Rab10 proteins act as opposing switches to regulate the delivery of supplies needed for synaptic potentiation during memory formation. Rab4 activation enhances delivery of neurotransmitter receptors to neural connections, while Rab10 activation diverts them away. These mechanisms are crucial for synaptic plasticity and may inform strategies for Alzheimer's disease resilience.
October 15, 2025 — Source

Eye-tracking offers measure of change in pre-clinical Alzheimer's disease
The effectiveness of eye-tracking technology in identifying people who have a genetic tendency to Alzheimer's disease, years before their symptoms show, has been highlighted in new research.
October 15, 2025 — Source

New brain imaging technique can detect early frontotemporal dementia
An advanced MRI technique measuring water molecule diffusion in brain gray matter can detect microstructural changes associated with hereditary frontotemporal dementia (FTD) before brain atrophy or symptoms appear. This method is more sensitive than traditional imaging, enabling earlier identification of at-risk individuals and monitoring of disease progression.
October 15, 2025 — Source

People with dementia less likely to be referred to allied health services by GPs
People with dementia are significantly less likely to be referred by general practitioners to allied health services compared to individuals with stroke or Parkinson's disease. Despite evidence supporting allied health interventions for dementia, referral rates remain low, indicating a need for improved awareness, care pathways, policy support, and workforce training in dementia care.
October 15, 2025 — Source

Health — Alzheimers — October 13th, 2025

Cholesterol-lowering drugs could reduce risk of dementia, study finds
Low cholesterol can reduce the risk of dementia, a new University of Bristol-led study with more than a million participants has shown.
October 13, 2025 — Source

Health — Alzheimers — October 10th, 2025

Dementia drug raises stroke risk—even in 'low-risk' patients, study shows
A major U.K. study of more than 165,000 dementia patients has found that risperidone raises stroke risk without exception, challenging safety assumptions by leaving no "safe group."
October 10, 2025 — Source

Health — Alzheimers — October 8th, 2025

Gold nanoparticle nasal spray delivers lithium safely to the brain
A new gold nanoparticle nasal spray delivers lithium directly to the brain, targeting Alzheimer's and bipolar disorder while avoiding harmful side effects.
October 8, 2025 — Source

Largest study of African American brain tissue reveals key Alzheimer gene activity
The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry (EA) individuals living in the U.S. Some of this is due to social determinants of health such as disparities in health care access and quality of education, biases in testing and higher rates of AD risk factors such as cardiovascular disease and diabetes in those who identify as African American.
October 8, 2025 — Source or Source

Rethinking Alzheimer's: Why this common gene variant is bad for your brain
The suspected causes of Alzheimer's disease are diverse, and its cures are, today, nonexistent.
October 8, 2025 — Source

Scientists Just Reversed Alzheimer's in Mice. Could They Do It in Humans?
Instead of targeting neurons, the researchers specifically sought to repair a critical part of the brain that keeps disease-inducing toxins out.
October 8, 2025 — Source

Health — Alzheimers — September 29th, 2025

HIV mystery uncovered: How the virus reprograms host cells to create perfect hiding places
For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating—and possibly even curing—the disease a seemingly insurmountable obstacle to achieve.
September 29, 2025 — Source

New evidence shows blood-brain barrier remains intact in Alzheimer's mouse model
Scientists at TTUHSC found the blood-brain barrier remains largely intact in a mouse model of Alzheimer's disease, challenging previous assumptions about drug delivery.
September 29, 2025 — Source or Source

Q&A: Expert discusses role in brain health, impact of Prop 14
Chemistry is essential for understanding the molecular mechanisms of neurodegenerative diseases, such as protein misfolding and amyloid aggregation in Alzheimer's and Parkinson's. Advanced chemical tools enable real-time study of these processes, informing drug design. State investment through Proposition 14 could accelerate research and translation of basic discoveries into clinical therapies in Texas.
September 29, 2025 — Source

Fiber-optic method allows real-time monitoring of Alzheimer's plaques in freely behaving mice
Alzheimer's disease is marked by the buildup of amyloid plaques in the brain, but most ways of studying these deposits in mouse models require sacrificing the animals. That limits researchers' ability to follow how the disease develops or how treatments work over time.
September 29, 2025 — Source

How gene mutations drive dementia in Parkinson's disease
Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain. But a new Nature Communications study has found that the cognitive deficits arise through a different—and unexpected—mechanism.
September 29, 2025 — Source

Health — Alzheimers — September 26th, 2025

Breakthrough in predicting Parkinson's and dementia in people with REM sleep behavior disorder
An international research team led by Universite de Montreal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.
September 26, 2025 — Source

EU approves contentious Alzheimer's medication
The European Union on Thursday approved the highly contentious Alzheimer's medication Kisunla under strict conditions, with the drug's effectiveness hotly debated by the medical community.
September 26, 2025 — Source

Isolated REM sleep behavior disorder may predict Parkinson's disease and dementia
Imaging biomarkers in individuals with isolated REM sleep behavior disorder (iRBD) can predict future development of Parkinson's disease or dementia with Lewy bodies. Reduced glymphatic function in the left brain hemisphere increases Parkinson's risk, while elevated free water in the basal nucleus of Meynert signals higher risk for dementia with Lewy bodies.
September 26, 2025 — Source

Health — Alzheimers — September 25th, 2025

AstroCapsules offer a new way to reduce brain inflammation
Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease. A collaborative research team from Houston Methodist and Rice University has developed a way to fight back with a tiny, bioengineered system to deliver anti-inflammatory proteins to specific targets in the brain.
September 25, 2025 — Source

New protein interaction map sheds light on how brain cell communication breaks down in Alzheimer's disease
A new study led by the Icahn School of Medicine at Mount Sinai offers one of the most comprehensive views yet of how brain cells interact in Alzheimer's disease, mapping protein networks that reveal communication failures and point to new therapeutic opportunities.
September 25, 2025 — Source

Tiny treatment system helps fight back against neuroinflammation in the brain
Neuroinflammation is linked to a host of detrimental brain disorders, including Alzheimer's and Parkinson's disease. A collaborative research team from Houston Methodist and Rice University has developed a way to fight back with a tiny, bioengineered system to deliver anti-inflammatory proteins to specific targets in the brain.
September 25, 2025 — Source

Health — Alzheimers — September 16th, 2025

Age influences amyloid positivity in Parkinson's disease without dementia
A new research paper was published in Volume 17, Issue 8 of Aging-US on August 6, 2025, titled "Age-related trends in amyloid positivity in Parkinson's disease without dementia."
September 16, 2025 — Source

Building bridges between Alzheimer's theories: Amyloid beta and inflammation converge on the same receptor
If there's one thing that's crystal clear about Alzheimer's disease, it's this: It eats away at neurons and the links between them, ultimately destroying the neural networks that underlie our memories.
September 16, 2025 — Source

Lifestyle changes show promise in preventing cognitive decline and Alzheimer's disease
An estimated 7.2 million Americans over age 65 currently live with Alzheimer's disease (AD). That number is expected to nearly double to 13.8 million by 2060. These increases reflect more than demographic shifts; they point to a growing public health crisis that requires a new, proactive approach. While chronological age is the strongest known risk factor for cognitive decline, losing cognitive function is not an inevitable part of aging.
September 16, 2025 — Source

Training hospital staff in person-centered dementia care improves recovery outcomes
A new study led by Prof. Lynn Chenoweth from UNSW's Center for Healthy Brain Aging (CHeBA) has shown that educating hospital staff in person-centered dementia care leads to better care experiences, greater staff confidence, and improved rehabilitation outcomes for older Australians.
September 16, 2025 — Source

Health — Alzheimers — September 9th, 2025

Brain iron levels detected by MRI can predict cognitive impairment and decline
A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published in Radiology.
September 9, 2025 — Source

Changing indoor environments could improve sleep for people living with dementia
Implementing changes to indoor environments, such as cooler bedrooms at night and increasing the amount of bright light during the day, could significantly improve sleep for people living with dementia, according to a study led by the University of Surrey.
September 9, 2025 — Source

How fat disables the brain's immune shield in Alzheimer's disease 
It was long thought that fat in the brain played no role in neurodegenerative diseases, but Purdue University researchers are challenging that assumption.
September 9, 2025 — Source

Research reveals a promising new target to thwart Alzheimer's decades before symptoms star
A person will have Alzheimer's years before ever knowing it. The disorienting erasure of memories, language, thoughts—in essence, all that makes up one's unique sense of self—is the final act of this enigmatic disease that spends decades disrupting vital processes and dismantling the brain's delicate structure.
September 9, 2025 — Source

Study of identical twins links faster aging to memory decline
New research from University of Virginia psychologists has found that "epigenetic clocks"—tools scientists use to estimate a person's biological age—can predict cognitive decline. The study, which focused on middle-aged twins, also found socioeconomic status plays a role.
September 9, 2025 — Source

Zero-burden technologies show that brighter days and cooler nights could improve sleep in dementia
Implementing changes to indoor environments, such as cooler bedrooms at night and increasing the amount of bright light during the day, could significantly improve sleep for people living with dementia, according to a study led by the University of Surrey.
September 9, 2025 — Source

Health — Alzheimers — September 4th, 2025

A 3-minute brainwave test could spot Alzheimer's years before symptoms
A quick brainwave test called Fastball can detect early signs of Alzheimer's at home, opening the door to faster diagnoses and treatments.
September 4, 2025 — Source

Building bridges in a memory care desert
In rural and underserved areas—particularly Native American communities—early signs of dementia often go unrecognized. This could be because access to specialized care is limited, and symptoms are easily mistaken for normal memory loss due to aging.
September 4, 2025 — Source

Gene variant slows down removal of debris in the brain, increasing Alzheimer's risk, say researchers
A type of brain cell that plays a vital role in maintaining neural networks and repairing injuries lies at the core of a promising new study on Alzheimer's disease from the USF Health Byrd Alzheimer's Center and Research Institute.
September 4, 2025 — Source

Higher education provides limited protection from Alzheimer's disease
Cognitive reserve (CR) is the brain's ability to maintain cognitive function despite age-related brain changes, damage or disease. It reflects an individual's capacity to cope with these changes by utilizing pre-existing cognitive strategies or developing compensatory mechanisms.
September 4, 2025 — Source

Smell loss emerges as the early behavioural sign of Alzheimer's
ew research reveals that immune cells attack brainstem nerve fibers linked to smell, making loss of smell the earliest detectable sign of Alzheimer's disease, and a potential window for earlier diagnosis.
September 4, 2025 — Source

Health — Alzheimers — September 1st, 2025

'Young' immune cells reverse signs of neurodegenerative brain changes in preclinical study
"Young" immune cells created by Cedars-Sinai investigators reversed signs of aging and Alzheimer's disease in the brains of laboratory mice, according to a study published in the journal Advanced Science.
September 1, 2025 — Source

Health — Alzheimers — August 29th, 2025

Altered gut immune system in Alzheimer's mouse model provides new target for therapeutics
The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD), providing a potential new therapeutic pathway for the memory-robbing malady.
August 29, 2025 — Source

Alzheimer's research uncovers a new therapeutic pathway for the memory-robbing malady
The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady. The research, published in the August 29, 2025 issue of Cell Reports, also shows that feeding the mice a high fiber diet reduces AD-related frailty, including tremor.
August 29, 2025 — Source

Health — Alzheimers — August 25th, 2025

Brain's blood flow could change how we understand and treat Alzheimer's
Over seven million Americans are living with Alzheimer's disease (AD), and the heartbreaking day-to-day battle with the effects of cognitive decline. According to the Alzheimer's Association, the brain changes that cause the disease actually begin 20 years or more before symptoms start, highlighting the critical need for early and accurate diagnosis. However, current diagnostic tools involve painful spinal taps, expensive scans and cognitive tests that can be limited in their accuracy.
August 25, 2025 — Source

Communication between tau and amyloid-&beta proteins found to mitigate Alzheimer's toxicity
An estimated 50 million people worldwide have dementia, with Alzheimer's disease—accounting for more than 70%—being the representative neurodegenerative brain disorder. A Korean research team has, for the first time, identified at the molecular level that tau and amyloid-&beta, the two key pathological proteins of Alzheimer's disease, directly communicate to regulate toxicity.
August 25, 2025 — Source

Having a sense of purpose may protect against dementia
Research into Blue Zones—regions of the world where people tend to live longer—shows that having a sense of purpose in life may help people live longer.
August 25, 2025 — Source

Health — Alzheimers — August 22nd, 2025

A startling omega-3 deficiency may explain women's Alzheimer's risk
Researchers discovered that women with Alzheimer's show a sharp loss of omega fatty acids, unlike men, pointing to sex-specific differences in the disease. The study suggests omega-rich diets could be key, but clinical trials are needed.
August 22, 2025 — Source

Berlin's waters carry bacterial traces of the city's population—with potential implications for the ecological status
A research team from the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) has investigated the interplay between hydrology and microbial communities in small water bodies in Berlin.
August 22, 2025 — Source

How a gift card could help speed up Alzheimer's clinical research
Effective strategies are needed to improve representation of marginalized groups in Alzheimer's clinical trials. Despite ongoing debate among researchers about the ethics of financial incentives for clinical trial enrollment, there has been little consensus on the appropriate use and size of incentives.
August 22, 2025 — Source

Health — Alzheimers — August 21st, 2025

Comorbidities in HIV: Big data study reveals molecular links
Why do people infected with the human immunodeficiency virus (HIV) often suffer from cardiovascular, liver, and other comorbidities? Researchers at the Center for Individualized Infection Medicine (CiiM) investigated this question as part of the 2000HIV study, a multi-omics cohort coordinated by several research centers in the Netherlands.
August 21, 2025 — Source

Do you take your own blood pressure at home? Here's how to choose the device that fits your arm best
Doctors are increasingly using blood pressure measurements taken at home to guide decisions about managing hypertension, such as whether you have hypertension in the first place, and whether you need to start or change medications. These readings can complement measurements taken in a doctor's office and can be done more often.
August 21, 2025 — Source

Midkine found to prevent Alzheimer's-related protein assemblies
Scientists at St. Jude Children's Research Hospital demonstrated for the first time that the protein midkine plays a preventative role against Alzheimer's disease. Midkine is known to accumulate in Alzheimer's disease patients. Now, researchers have connected it with amyloid beta, a protein that accumulates in the brain, causing assemblies that are a hallmark of Alzheimer's.
August 21, 2025 — Source or Source

Study finds adults with hearing loss using hearing aids have reduced dementia risk
Lily Francis, M.B.B.S., from the University of Texas Health Science Center at San Antonio, and colleagues conducted a prospective association study to examine whether hearing aid use by people with HL is associated with a lower risk for incident dementia in the Framingham Heart Study original and offspring cohorts.
August 21, 2025 — Source

Health — Alzheimers — August 19th, 2025

Eye movement patterns reveal subtle signs of cognitive and memory decline
A multi-institution team across Canada and the West Indies reports that gaze patterns can serve as a sensitive marker of cognitive decline, with associated reductions in explorative, adaptive, and differentiated visual sampling of the environment
August 19, 2025 — Source

Health — Alzheimers — August 17th, 2025

Dementia-like protein clumping found in early pancreatic cancer cells
Cancer Research UK-funded scientists have uncovered dementia-like behavior in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.
August 17, 2025 — Source

Health — Alzheimers — August 11th, 2025

Alzheimer's disease: The complexities of clinical trials
Cedars-Sinai physician-scientists joined peers from around the world at the Alzheimer's Association International Conference in July. The scientific presentations at the conference included data from clinical trials of potential therapies for the neurodegenerative disease.
August 11, 2025 — Source

Cost-effective AI tool can predict markers of Alzheimer's disease
Researchers at Boston University Chobanian & Avedisian School of Medicine have built an artificial intelligence (AI) tool that can accurately predict key signs of Alzheimer's disease—such as the presence of sticky proteins called amyloid beta and tau—using common and less expensive tests like brain scans, memory checks and health records.
August 11, 2025 — Source

Nuclear speckle rejuvenation could be the next frontier for treating neurodegeneration
Targeting cellular structures called nuclear speckles could be a completely new approach for treating proteinopathies—diseases driven by abnormal accumulation of misfolded proteins—such as Alzheimer's, Parkinson's and prion diseases, according to new research published in Nature Communications and led by the University of Pittsburgh.
August 11, 2025 — Source

Wildfire smoke increases risks of dementia, asthma and other ailments, researchers say
moke that has blanketed the state this month could take a toll on the health of Michiganians long after clearing.
August 11, 2025 — Source

Health — Alzheimers — August 8th, 2025

'A tipping point': Expert gives update from frontiers of Alzheimer's disease research
One-third of people older than 85 in the United States are estimated to live with Alzheimer's disease today, according to the National Institute on Aging. The condition's characteristic long, slow decline places an enormous burden on families and on society. While the need for new treatments is urgent, Alzheimer's is a complex disease that requires multidisciplinary research across a wide range of specialties.
August 8, 2025 — Source

Health — Alzheimers — July 25th, 2025

Heavy smoking linked to atrophy in Alzheimer's brain regions
New MRI research reveals that heavy smoking can shrink key brain regions tied to memory and cognition, and excess weight might intensify the damage, raising fresh questions about dementia prevention.
July 25, 2025 — Source

Health — Alzheimers — July 22nd, 2025

Dementia risk does not differ with GLP-1 RAs, DPP4is for seniors with type 2 diabetes, study finds
For older adults with diabetes, there is no clear evidence to suggest that the incidence of dementia differs for those using glucagon-like peptide 1 receptor agonists (GLP-1 RAs) versus dipeptidyl peptidase-4 inhibitors (DPP4is), according to a study published online in the Annals of Internal Medicine.
July 22, 2025 — Source

Inflammatory bowel disease possibly accelerates dementia
"Our results indicate that inflammatory bowel disease (IBD) can worsen cognitive function in people with dementia," says principal investigator Hong Xu, assistant professor at the Department of Neurobiology, Care Sciences and Society at Karolinska Institutet in Sweden. "This opens the door to more effective care strategies with closer monitoring and targeted treatment, which will hopefully be able to improve the quality of these individuals' lives."
July 22, 2025 — Source

Health — Alzheimers — July 19th, 2025

Doctors used music instead of medication—what they saw in dementia patients was remarkable
Research finds music therapy could be used on NHS wards as an alternative to drugs
July 19, 2025 — Source

Health — Alzheimers — July 17th, 2025

AI-guided patient stratification boosts Alzheimer's trial outcomes and efficiency
Scientists have used an AI model to reassess the results of a completed clinical trial for an Alzheimer's disease drug. They found the drug slowed cognitive decline by 46% in a group of patients with early stage, slow-progressing mild cognitive impairment -- a condition that can progress to Alzheimer's.
July 17, 2025 — Source

Health — Alzheimers — July 14th, 2025

Blood test detects early signs of Alzheimer's in middle age
A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease could allow earlier detection of the disease. This would allow preventive treatment to be targeted at the right individuals while the disease is still at the mild stage.
July 14, 2025 — Source

Brain biomarkers of Alzheimer's disease can be detected as early as middle age
A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease could allow earlier detection of the disease. This would allow preventive treatment to be targeted at the right individuals while the disease is still at the mild stage.
July 14, 2025 — Source

Demystifying the link between major depression and Alzheimer's disease
More than 7 million people in the United States live with Alzheimer's disease and related dementia (ADRD). Some risk factors for ADRD, like genetics, can't be controlled, but others can be treated. One of the most prevalent is depression (known clinically as major depressive disorder, or MDD). Between 11.1% and 14.7% of ADRD cases—affecting roughly 1 million individuals in the US—are attributable to MDD.
July 14, 2025 — Source

SARS-CoV-2 can cause buildup of Alzheimer's-related peptides in retina
A new Yale study has found a promising target for treating the brain fog that can follow COVID-19 and offers new insight into a hypothesis about the origin of Alzheimer's disease.
July 14, 2025 — Source

This Common Pain Med Could Be Raising Dementia Risk
Gabapentin is routinely used to treat nerve pain and restless leg syndrome, but it might be riskier to our brain health than currently thought.
July 14, 2025 — Source

Health — Alzheimers — July 12th, 2025

Scientists just found 200+ hidden proteins that may drive Alzheimer's
New Johns Hopkins study of rats suggests A-beta and tau amyloids are 'just the tip of the iceberg'.
July 12, 2025 — Source

Health — Alzheimers — July 10th, 2025

Q&A: Team discusses uncovering ApoE3 Christchurch's multi-pathway defense against Alzheimer's
Researchers have published a paper in Alzheimer's & Dementia, titled "ApoE3 Christchurch and tau interaction as a protective mechanism against Alzheimer's disease."
July 10, 2025 — Source

Study links COVID-19 and bacterial infection to Alzheimer's disease
A recent review by researchers at Philadelphia College of Osteopathic Medicine (PCOM) shows Chlamydia pneumoniae (Cpn) and SARS-CoV-2 infections may play a role in the pathogenesis of Alzheimer's disease.
July 10, 2025 — Source

Your Brain's Hidden Defenses Against Alzheimer's
UCSF researchers create "Google Maps" for how tau moves in the brain of Alzheimer's patients.
July 10, 2025 — Source

Health — Alzheimers — July 7th, 2025

New blood biomarker predicts progression of Alzheimer's disease even in its earliest stages
A team of researchers at the Sant Pau Research Institute (IR Sant Pau) has demonstrated that the plasma biomarker p-tau217, obtained through a simple blood test, can predict the clinical progression of Alzheimer's disease even in its earliest stages, when symptoms are not yet evident.
July 7, 2025 — Source

New study maps four key pathways to Alzheimer's disease
UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated risk factors.
July 7, 2025 — Source

UCLA Health researchers discover four pathways leading to Alzheimer's disease
UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over time rather than from isolated risk factors.
July 7, 2025 — Source

Health — Alzheimers — July 2nd, 2025

Alzheimer's-related protein found to drive lung cancer spread to brain
Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer's disease helps lung cancer spread to the brain—a discovery that offers hope that existing Alzheimer's drugs could be repurposed in preventing cancer's spread.
July 2, 2025 — Source

Blood stem cell mutations linked to lower risk of late-onset Alzheimer's disease
A team led by researchers at Baylor College of Medicine discovered that both a mouse model and people carrying blood stem cells with mutations in the gene TET2, but not in the gene DNMT3A, had a lower risk of developing Alzheimer's disease. Their study proposes a mechanism that can protect against the disease and opens new avenues for potential strategies to control the emergence and progression of this devastating condition.
July 2, 2025 — Source

Health — Alzheimers — June 30th, 2025

A new blood test detects Alzheimer's with single-molecule precision
Researchers have developed a blood test that detects Alzheimer's biomarkers at single-molecule levels, enabling earlier, non-invasive diagnosis using extracellular vesicles.
June 30, 2025 — Source

Discovery of key brain repair mechanism in vascular dementia reveals promising therapeutic target
A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice.
June 30, 2025 — Source

Low-intensity brain stimulation may restore neuron health in Alzheimer's disease
Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people worldwide. Synapses are points of communication between neural cells that are malleable to change based on our experiences. By adding, removing, strengthening, or weakening synaptic contacts, our brain encodes new events or forgets previous ones.
June 30, 2025 — Source

Scientists just found a sugar switch that protects your brain from Alzheimer's
In addition to a new approach in Alzheimer's research, study from Buck Institute could explain why GLP-1 drugs show promise against dementia
June 30, 2025 — Source

Health — Alzheimers — June 29th, 2025

An exercise drug? Harnessing the cognitive benefits of a workout for Alzheimer's patients with mobility issues
For years, researchers have seen a connection between exercise and the progression of cognitive disorders such as Alzheimer's—but ramping up movement isn't possible for many patients. A new study published in Nature Neuroscience looks at how to mimic those benefits without having to hit the gym.
June 29, 2025 — Source

Health — Alzheimers — June 28th, 2025

AI tool detects 9 types of dementia from a single brain scan
Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely available scan—a transformative advance in early, accurate diagnosis.
June 28, 2025 — Source

Health — Alzheimers — June 25th, 2025

Dementia cells' misplaced genetic messages may be re-established by drug currently in clinical trials
Researchers at the Francis Crick Institute and UCL have shown that genetic messages are misplaced in nerve cells in a model of Alzheimer's disease and frontotemporal dementia. These messages mostly affect the function of the mitochondria, the cell's energy producers, and can be re-established using a drug currently in clinical trials.
June 25, 2025 — Source

Dementia: Are younger generations really less likely to develop the disorder, as a recent study has claimed?
Dementia affects over 57 million people worldwide—and this number is only projected to grow. By 2030, 78 million people are estimated to have dementia. By 2050, it's projected that number will reach 139 million people.
June 25, 2025 — Source

Early biomarkers of brain damage progression in Alzheimer's disease revealed
A new study led by scientists from BGI Genomics' Institute of Intelligent Medical Research (IIMR) has identified early biomarkers and disease neurons associated with Alzheimer's Disease (AD) pathology.
June 25, 2025 — Source

Critical brain link could explain how Alzheimer's takes hold
A crucial link between the brain's cleaning system and deterioration of neurons associated with Alzheimer's disease has been discovered by University of Queensland researchers.
June 25, 2025 — Source

Living in more disadvantaged neighborhoods may increase risk of inflammation and dementia biomarkers
People living in more disadvantaged neighborhoods may be more likely to have biomarkers for inflammation and Alzheimer's disease, according to a study published in Neurology. The study does not prove that neighborhood factors cause these biomarkers: it only shows an association.
June 25, 2025 — Source

Q&A: Researcher discusses quest to halt neurodegenerative disorders such as Alzheimer's disease
Misplaced car keys, forgotten names and other lapses in memory are a normal part of life, especially as you age. However, more serious memory problems can be a sign of cognitive impairment or dementia like Alzheimer's disease.
June 25, 2025 — Source

Space-based experiment opens new avenues in Alzheimer's research
A collaborative team of researchers has succeeded in revealing the high-resolution structures of amyloid &beta (A&beta40) fibrils carrying the Tottori-type familial mutation (D7N) by leveraging the microgravity environment aboard the International Space Station's "Kibo" module.
June 25, 2025 — Source

Study reveals how Alzheimer's disease and attention shape our ability to remember
Why do some older adults easily remember the name of a new acquaintance or the location of their keys, while others struggle with everyday recall—despite appearing equally healthy?
June 25, 2025 — Source

The brain's sweet spot: How criticality could unlock learning, memory—and prevent Alzheimer's
Our brains may work best when teetering on the edge of chaos. A new theory suggests that criticality a sweet spot between order and randomness is the secret to learning, memory, and adaptability. When brains drift from this state, diseases like Alzheimer s can take hold. Detecting and restoring criticality could transform diagnosis and treatment.
June 25, 2025 — Source

Why NICE was right to say no—for now—to new Alzheimer's drugs
The UK's National Institute for Health and Care Excellence (NICE) has declined to recommend two new Alzheimer's drugs for routine NHS use in England. While disappointing for some families affected by dementia, this decision reflects a cautious and evidence-based approach that protects patients and public funds.
June 25, 2025 — Source

Health — Alzheimers — June 23rd, 2025

Protective gene variant slows Alzheimer’s by taming brain inflammation
A rare gene mutation that delays Alzheimer's disease does so by damping inflammatory signaling in brain-resident immune cells, according to a preclinical study led by investigators at Weill Cornell Medicine. The finding adds to growing evidence that brain inflammation is a major driver of neurodegenerative disorders such as Alzheimer's-and that it may be a key therapeutic target for these disorders.
June 23, 2025 — Source

Sugary drinks in older age show no effect on dementia, large study finds
Dementia, marked by neurodegeneration and life-disrupting cognitive decline, burdens individuals and health-care systems. Modifiable factors, particularly diet, are considered prime targets for prevention efforts. Excessive sugar intake fuels obesity and diabetes, which are known dementia risk factors. Sugar-sweetened drinks are a major sugar source for roughly 20% of older Americans.
June 23, 2025 — Source

Health — Alzheimers — June 21st, 2025

Dementia caregivers have modifiable risk factors increasing their own risk
Six in 10 dementia caregivers report having at least one modifiable risk factor that could increase their own chances of developing dementia, according to a report issued June 12 by the Alzheimer's Association.
June 21, 2025 — Source

Health — Alzheimers — June 20th, 2025

How an Alzheimer's peptide and a blood protein may combine to drive early disease pathology
Scientists have long known that the Alzheimer's brain often features abnormal plaques and tangles, and recent studies have highlighted the role that the brain's vascular system plays in disease progression. But for decades, this knowledge has failed to translate into fully effective treatments. The lack of progress is largely due to the fact that, despite landmark findings, the precise pathway of neurodegeneration is still unclear.
June 20, 2025 — Source

Retinal asymmetry between eyes may serve as early indicator of cognitive frailty
A new study led by researchers at National Taiwan University (NTU) reveals that subtle differences in retinal thickness between the eyes—known as inter-eye retinal asymmetry—may serve as an early and accessible biomarker for cognitive frailty, a high-risk condition combining mild cognitive impairment with physical frailty.
June 20, 2025 — Source

Targeting ST6Gal-I shows promise in reducing Alzheimer's disease pathology
Alzheimer's disease is a progressive neurodegenerative disorder characterized by the gradual loss of memory and cognitive functions.
June 20, 2025 — Source

Health — Alzheimers — June 18th, 2025

Could a busier social life be a very early sign of Alzheimer's?
Many experts believe that social isolation is a risk factor for Alzheimer's disease. But a new study, led by UC San Francisco and Boston University, examined the social habits and genetic data of half a million Britons whose average age was 56, and found that the disease may make them more sociable rather than less—at least in the early stages.
June 18, 2025 — Source

Health — Alzheimers — June 16th, 2025

Indiana University researcher helps develop FDA-approved Alzheimer's test
A first-of-its-kind blood test to detect amyloid plaques in the brain associated with Alzheimer's disease recently received clearance from the U.S. Food and Drug Administration. An Indiana University School of Medicine researcher who helped lead the discovery and development of one of the biomarkers the test identifies hopes it will provide greater access and a more accurate diagnosis for patients.
June 16, 2025 — Source

Key blood proteins which predict future cognitive decline identified
In a study that holds significance for individuals with cerebrovascular disease, scientists from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have found proteins in the blood that predict future cognitive decline and dementia.
June 16, 2025 — Source

Most niece and nephew dementia caregivers take on role without prior planning, study finds
A Virginia Tech study provides new insights about nieces and nephews taking care of aging relatives living with dementia.
June 16, 2025 — Source

Nanoneedle patch offers painless alternative to traditional cancer biopsies
A patch containing tens of millions of microscopic nanoneedles could soon replace traditional biopsies, scientists have found. The patch offers a painless and less invasive alternative for millions of patients worldwide who undergo biopsies each year to detect and monitor diseases like cancer and Alzheimer's.
June 16, 2025 — Source or Source

Health — Alzheimers — June 13th, 2025

How a neurologist faces the disease that is slowly stealing his cognitive powers: Q&A
It was 2006 when Dr. Daniel Gibbs first noticed he was losing his sense of smell. But it wasn't what he didn't smell that tipped him off that something might be wrong.
June 13, 2025 — Source

UK study finds small proportion of early Alzheimer's patients suitable for latest treatments
UK study finds small proportion of early Alzheimer's patients suitable for latest treatments
June 13, 2025 — Source

Health — Alzheimers — June 6th, 2025

Blood test shows 95% accuracy for Alzheimer's disease diagnosis in outpatient memory clinics
Alzheimer's disease, marked by memory loss, trouble concentrating and thinking, and changes in personality and behavior, devastates patients, their families and loved ones. With new treatments available for people with early signs of Alzheimer's disease, there is a growing need for accessible and cost-effective tests to diagnose Alzheimer's disease sooner.
June 6, 2025 — Source

Hong Kong health service leverages world's first retinal imaging AI for Alzheimer's detection
The AI, trained on around 13,000 fundus images from over 600 Alzheimer's patients, has demonstrated up to 92% accuracy.
June 6, 2025 — Source

Health — Alzheimers — June 3rd, 2025

Digital screening during primary care visits may lead to earlier dementia detection and care
A trio of studies led by Indiana University School of Medicine researchers has found that digital testing during primary care visits showed some promise as a tool for early identification of Alzheimer's disease and dementia in older adults.
June 3, 2025 — Source

Epilepsy is more common in patients with frontotemporal dementia than expected
According to a recent study, in patients with frontotemporal dementia (FTD), epileptic seizures are significantly more common than previously known. The discovery deepens understanding of the symptoms of this memory disorder and emphasises the importance of taking epileptic seizures into account in the treatment and monitoring of patients.
June 3, 2025 — Source

MIND diet linked to lower risk of dementia across diverse populations
As the U.S. population ages and dementia cases rise, many people are asking whether it is possible to prevent this devastating disease. According to a new study, the answer may be on your plate: People who followed a dietary pattern known as the MIND diet were significantly less likely to develop Alzheimer's disease or related forms of dementia.
June 3, 2025 — Source

Health — Alzheimers — May 30th, 2025

Common gene variant doubles dementia risk for men, study suggests
New research has found that men who carry a common genetic variant are twice as likely to develop dementia in their lifetime compared to women.
May 30, 2025 — Source

Health — Alzheimers — May 28th, 2025

A common sleep aid blocks neurodegeneration in mice
A common sleep aid restores healthier sleep patterns and protects mice from the brain damage seen in neurodegenerative disorders, such as Alzheimer's disease, according to new research from Washington University School of Medicine in St. Louis. The drug, lemborexant, prevents the harmful buildup of an abnormal form of a protein called tau in the brain, reducing the inflammatory brain damage tau is known to cause in Alzheimer's.
May 28, 2025 — Source

Health — Alzheimers — May 27th, 2025

Rural Georgians lack access to Alzheimer's disease treatment
Rural Georgians may find it difficult to access medication that could slow the progression of Alzheimer's disease, according to a new study from the University of Georgia.
May 27, 2025 — Source

Untreated sleep apnea may be risk factor for vascular dementia
People who have obstructive sleep apnea may have an increased risk of dementia if left untreated, according to a new study of UK electronic health care records.
May 27, 2025 — Source

Health — Alzheimers — May 22nd, 2025

Potential new drug that protects blood-brain barrier shows promise against Alzheimer's
Worldwide, more than 55 million people suffer from dementia caused by Alzheimer's disease (AD) and other conditions that destroy cells in the brain and nervous system.
May 22, 2025 — Source

Health — Alzheimers — May 13th, 2025

Dementia risk depends on more than lifestyle factors: Overstating this can cause stigma and blame
As public awareness of dementia grows, so too does the appetite for prevention. Global headlines tout the benefits of exercise, diet, brain training and social activity in reducing dementia risk.
May 13, 2025 — Source

Molecule reverses cognitive deficits associated with aging and dementia in animal tests
In Brazil, researchers from the Federal University of Rio de Janeiro (UFRJ) and collaborators from the University of São Paulo (USP) have discovered that a molecule called Hevin can reverse cognitive impairment. The study, conducted in mice, showed that this glycoprotein produced by brain cells (astrocytes) is able to increase the connections between neurons (synapses) in aged rodents and in animal models of Alzheimer's disease.
May 13, 2025 — Source

Sedentary behavior is an independent risk factor for Alzheimer's disease, 7-year study reveals
Over 6 million Americans are impacted by Alzheimer's disease, and researchers from Vanderbilt University Medical Center and the University of Pittsburgh are discovering how lifestyle habits can impact the likelihood of developing the disease.
May 13, 2025 — Source or Source

Health — Alzheimers — May 9th, 2025

Cell's protein cleanup fails when crucial enzyme is blocked, study finds
In neurodegenerative diseases such as Alzheimer's or Parkinson's, proteins accumulate in the body's cells, fold incorrectly and clump together to form larger aggregates.
May 9, 2025 — Source

Health — Alzheimers — May 6th, 2025

Alzheimer's risk: Many say they want answers, but fewer choose to know the truth
As researchers make progress in understanding how Alzheimer's disease develops, there are growing opportunities for healthy research participants to learn their risk of developing Alzheimer's disease dementia in the future. While many organizations often advocate for investigators to share risk estimates with individual participants, there are ethical concerns around doing so, given that there are no medical interventions to change that risk.
May 6, 2025 — Source

Alzheimer's: Certain combinations of prescription drugs may slow progression of disease, according to mice study
Millions of older adults take five or more prescription drugs every day to manage chronic illnesses. While polypharmacy is often necessary, this practice has also been linked to many negative health outcomes in older adults—including memory problems, increased risk of falls and greater frailty.
May 6, 2025 — Source

Developing a probiotic cocktail that may help ward off dementia
Hariom Yadav, Ph.D., can't get a particular cocktail off his mind—especially because our aging population potentially could benefit from the benefits for brain health that this punch may pack.
May 6, 2025 — Source

Most people say they want to know their risk for Alzheimer's dementia, fewer follow through
Among reasons for declining, research participants say knowing would be a burden to themselves, family members
May 6, 2025 — Source

Health — Alzheimers — May 5th, 2025

Alzheimer's 'genetic clock' model offers timeline for disease onset in families
A group of researchers in the lab of Prof. Lucía Chávez Gutierrez (VIB-KU Leuven) has unraveled the genetic contributions to familial Alzheimer's Disease development and revealed how specific mutations act as a clock to predict the disease age of onset.
May 5, 2025 — Source

Boosting glucose metabolism in glial cells reduces neurodegeneration in fruit flies
Researchers from Tokyo Metropolitan University have discovered that impaired glucose metabolism in glial cells, a type of cell in our nervous system, plays a key role in the degeneration caused by Alzheimer's disease. Using fruit fly retinas, they showed that promoting glucose metabolism in glial cells with tau protein build-up, like in Alzheimer's patients, helps relieve inflammation and photoreceptor degeneration. Their findings present an exciting new therapeutic target for treating neurodegenerative conditions.
May 5, 2025 — Source

Menopause symptoms may be critical to understanding Alzheimer's disease risk in women
Hot flashes, night sweats, vaginal dryness, urinary tract infections, irregular periods, low libido, trouble sleeping, brain fog, mood swings—and in rare cases, even a burning tongue sensation. What might all these symptoms have in common?
May 5, 2025 — Source

New brain mapping technique sheds light on Alzheimer's development
Researchers at Tulane University have created a first-of-its-kind subcellular map of an area of the brain commonly affected by Alzheimer's disease, a key step toward unraveling the mysteries of how the degenerative brain disease develops.
May 5, 2025 — Source

Health — Alzheimers — May 2nd, 2025

Estimated 7.2 million Americans 65 years and older have Alzheimer's dementia
An estimated 7.2 million Americans aged 65 years and older are living with Alzheimer's dementia, and almost all adults feel it is important to diagnose the disease in the early stages, according to a report published by the Alzheimer's Association.
May 2, 2025 — Source

Health — Alzheimers — April 28th, 2025

When they don't recognize you anymore
It happened more than a decade ago, but the moment remains with her.
April 28, 2025 — Source or Source

Health — Alzheimers — April 25th, 2025

AI helps unravel a cause of Alzheimer's disease and identify a therapeutic candidate
A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function. Researchers at the University of California San Diego used artificial intelligence to help both unravel this mystery of Alzheimer's disease and discover a potential treatment that obstructs the gene's moonlighting role.
April 25, 2025 — Source

Health — Alzheimers — April 22nd, 2025

Hearing loss in older adults linked to nearly one-third of dementia cases
A multi‑institution research team including Columbia, Vanderbilt, Johns Hopkins and others, report that nearly one in three new dementia cases in older adults is associated with hearing loss, based on statistical modeling of population data.
April 22, 2025 — Source

How to Protect Your Memory
It's natural to sometimes lose your train of thought or misplace your keys. But there are strategies for improving your recall.
April 22, 2025 — Source

Health — Alzheimers — April 11th, 2025

First participant with Down syndrome joins Alzheimer's prevention trial
Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein (APP) for the potential treatment of Alzheimer's disease (AD), which is initially being studied in adults with Down syndrome (DS) who have a genetic risk of developing AD.
April 11, 2025 — Source

Health — Alzheimers — April 7th, 2025

Exploring the link between blood flow, brain stiffness and Alzheimer's risk
Researchers have discovered that increased blood flow leads to stiffness in the hippocampus, a region of the brain that plays important roles in learning and memory. The hippocampus is one of the first areas in the brain affected by Alzheimer's disease, a brain disorder that erodes memory and thinking skills, as well as the ability to do daily tasks.
April 7, 2025 — Source

Lower LDL cholesterol linked to reduced dementia risk
New research shows that maintaining LDL-C levels below 70 mg/dL is associated with a significantly lower risk of all-cause and Alzheimer's-related dementia—even among statin users.
April 7, 2025 — Source

Health — Alzheimers — April 2nd, 2025

Blood test can predict dementia risk up to 10 years in advance, study shows
Researchers at Karolinska Institutet have demonstrated how specific biomarkers in the blood can predict the development of dementia up to 10 years before diagnosis, among older adults living independently in the community.
April 2, 2025 — Source

One in five people with dementia receive no care, global study finds
As the world's population rapidly ages, a new study led by researchers at the Yale School of Public Health finds that people living with dementia are struggling at an alarming rate. Heightening the sense of despair was an additional finding that this lack of care has persisted for years.
April 2, 2025 — Source

Study strengthens link between shingles vaccine and lower dementia risk
An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia. In a new study led by Stanford Medicine, researchers analyzing the health records of Welsh older adults discovered that those who received the shingles vaccine were 20% less likely to develop dementia over the next seven years than those who did not receive the vaccine.
April 2, 2025 — Source or Source

Health — Alzheimers — March 28th, 2025

Protein 'seeds' trigger key pathological features of ALS and frontotemporal dementia
Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a study published in Neuron, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.
March 28, 2025 — Source

Health — Alzheimers — March 21st, 2025

Renewal processes in the cell: Disruptions favor diseases such as Alzheimer's and Parkinson's, study finds
In an international research collaboration involving the University Medical Center Göttingen (UMG), researchers have produced the most complete map to date of how long different proteins persist in many tissues of the body. They were able to identify a mechanism that increases the stability of proteins and thus favors neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
March 21, 2025 — Source

Unlocking dopamine's hidden role: Protective modification of Tau revealed
Using a novel quantitative chemoproteomic strategy, a research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University has uncovered a protective role of dopamine (DA) in regulating the function of the microtubule-associated protein Tau. This discovery deepens our understanding of dopamine's physiological and pathological roles in the human brain.
March 21, 2025 — Source

Health — Alzheimers — March 17th, 2025

How does education affect Alzheimer's and dementia risk? It's about more than degree attainment
Education has long been associated with reduced risk of Alzheimer's disease and related dementias, but a new study reveals that this protection extends far beyond diplomas and degrees. Co-led by researchers at The University of Texas at Austin, the University of Minnesota, the University of Wisconsin-Madison and Columbia University, the study investigated how high school contexts, opportunities and outcomes shape midlife cognition even among people with the same completed degrees.
March 17, 2025 — Source

Health — Alzheimers — March 14th, 2025

Decreased levels of TDP-43 gene may be contributing to neurodegenerative diseases like Alzheimer's and ALS
In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease, and the progressive damage to the brain's frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).
March 14, 2025 — Source

Researchers develop computational tools to safeguard privacy without degrading voice-based cognitive markers
Digital voice recordings contain valuable information that can indicate an individual's cognitive health, offering a non-invasive and efficient method for assessment. Research has demonstrated that digital voice measures can detect early signs of cognitive decline by analyzing features such as speech rate, articulation, pitch variation and pauses, which may signal cognitive impairment when deviating from normative patterns.
March 14, 2025 — Source

Health — Alzheimers — March 11th, 2025

Blood test shows promise for early detection of dementia in people with a certain sleep disorder
For people with a certain sleep disorder, a simple blood test could help predict the development of dementia years before symptoms appear, a new study indicates.
March 11, 2025 — Source

New technique reveals how axon swellings could be treated in Alzheimer's disease
For decades, scientists have focused on amyloid plaques—abnormal clumps of misfolded proteins that accumulate between neurons—as a therapeutic target for Alzheimer's disease. But anti-amyloid therapies haven't made strong headway in treating the devastating condition.
March 11, 2025 — Source

Health — Alzheimers — March 10th, 2025

Regular updates to cognitive data improve Alzheimer's prediction accuracy
In a study led by Honghuang Lin, Ph.D., professor of medicine and co-director of the Program in Digital Medicine at UMass Chan Medical School, researchers developed a dynamic prediction model for Alzheimer's disease based on continually monitoring and updating information on cognitive functions.
March 10, 2025 — Source

Health — Alzheimers — February 28th, 2025

Key form of tau protein identified for understanding and treating Alzheimer's disease
A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells (iPSCs), the international team has been able to show that a specific form of the tau protein, known as the 1N4R isoform, is responsible for mediating the toxic effects of protein clumps in human brain cells.
February 28, 2025 — Source or Source

Health — Alzheimers — February 17th, 2025

Alzheimer's brain inflammation: Immune cells react differently to amyloid-beta, research suggests
Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease. Unlike the acute, short-lived inflammation that combats infection, the inflammation associated with Alzheimer's becomes chronic and persistent. Scientists have been trying to understand why this happens.
February 17, 2025 — Source

Lecanemab and donanemab slow Alzheimer's decline, but is the benefit worth the cost?
New research shows that lecanemab and donanemab can slow cognitive decline and extend patients' independence in daily activities. But with high costs and risks, are these treatments truly meaningful for Alzheimer's patients and their families?
February 17, 2025 — Source

Novel antibody discovery platform may inform Alzheimer's and Parkinson's research
In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and researchers have developed novel methods to generate aggregate-specific antibodies as specific probes or modulators of the aggregation process.
February 17, 2025 — Source

Health — Alzheimers — February 7th, 2025

Cerebrospinal biomarker test can detect Alzheimer's pathology earlier, study shows
Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research published today in Nature Medicine suggests.
February 10, 2025 — Source

Decline in BMI, waist circumference seen in decade before dementia
Zimu Wu, Ph.D., from Monash University in Melbourne, Australia, and colleagues conducted a case-control study involving a sample drawn from community-dwelling participants in the Aspirin in Reducing Events in the Elderly study. Dementia cases were matched to dementia-free controls for sociodemographic characteristics and time of diagnosis.
February 7, 2025 — Source

Epistasis: Unlocking the secrets of complex diseases
Imagine your doctor calls you to discuss the results of your genetic testing. They tell you your results indicate you are highly likely to develop Alzheimer's disease. But not to worry, because they caught it early, you can start a personalized course of treatment tailored to your unique genetic makeup right away.
February 7, 2025 — Source

Experts outline key research areas in neuropalliative care
Neurological disease, from Alzheimer's disease to stroke and epilepsy, can impact a person's life in many ways. It can alter their ability to speak, move, think or lead an independent life. And it can have a significant impact on their families and loved ones, too.
February 7, 2025 — Source

Lab holding Ebola in DRC's Goma 'safe': WHO
A laboratory holding Ebola and other dangerous pathogens in the eastern DR Congo city of Goma—which has been seized by the M23 armed group—is safe, WHO said Friday.
February 7, 2025 — Source

Measles outbreak mounts among children in one of Texas' least vaccinated counties
A measles outbreak is growing in a Texas county with dangerously low vaccination rates.
February 7, 2025 — Source

New biomarker test detects early tau tangles in Alzheimer's disease
Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research published today in Nature Medicine suggests.
February 10, 2025 — Source

Health — Alzheimers — February 5th, 2025

Diet may influence risk of depression and Alzheimer's disease
New research from Edith Cowan University (ECU) has shown that diet could influence the risk of both depression and Alzheimer's disease (AD). Evidence suggests that depressive symptoms are both a risk factor for AD and a reaction to early memory problems.
February 5th, 2025 — Source

Health — Alzheimers — February 3rd, 2025

A neurovascular approach to detecting Alzheimer's disease
Research led by Lancaster University has revealed clear evidence that changes in the orchestration of brain oxygenation dynamics and neuronal function in Alzheimer's disease contribute to the neurodegeneration.
February 3rd, 2025 — Source

Alzheimer's disease linked to disrupted brain oxygenation and neuronal function
Research led by Lancaster University has revealed clear evidence that changes in the orchestration of brain oxygenation dynamics and neuronal function in Alzheimer's disease contribute to the neurodegeneration.
February 3rd, 2025 — Source

Health — Alzheimers — January 22nd, 2025

Editing embryos to prevent genetic diseases: Study sparks ethical debate
Scientists from a collaboration of Australian research institutions have proposed that editing multiple genetic variants in human embryos could significantly lower the likelihood of developing complex diseases such as coronary artery disease, Alzheimer's, major depressive disorder, diabetes, and schizophrenia.
January 22nd, 2025 — Source

Processed red meat isn't just bad for your heart, it's also associated with dementia
Less red meat is good for the planet and a rowing number of people have started the new year resolving to pursue a meat-free diet.
January 22nd, 2025 — Source

Health — Alzheimers — January 20th, 2025

Do big personality changes predict Alzheimer's? Not necessarily, study says
For decades, scientists have been trying to identify early signs of memory impairment in adults in an attempt to screen for or even slow down the onset of cognitive decline. Some clinicians believe that major personality changes, such as an increase in neuroticism, could be a canary in the coal mine for Alzheimer's disease and other types of dementia.
January 20th, 2025 — Source

Molecular mechanism of ergothioneine decoded: Mushroom compound may lead to prolonged health
Many people wish not only to live as long as possible, but above all to do so without any health restrictions. However, with increasing age, the risk of age-related diseases such as Alzheimer's or sarcopenia (loss of muscle mass and muscle strength with age) also increases.
January 20th, 2025 — Source

Health — Alzheimers — January 17th, 2025

Fluorescent probes illuminate cholesterol and Alzheimer's research
The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.
January 17th, 2025 — Source

Genetically modified mice hint at tau hyperphosphorylation's early role in neurodegenerative diseases
Tau is a microtubule-associated protein that helps to stabilize the structure of neurons, specifically by supporting microtubules, cylindrical structures that contribute to cell motility, intracellular transport and the maintenance of a cell's shape over time. While tau has an important neurophysiological function, when it undergoes pathological changes and accumulates in the brain, this protein has been found to contribute to some neurodegenerative diseases, broadly defined as tauopathies.
January 17th, 2025 — Source

Hanging up the car keys hard for people with young onset dementia: Study highlights need for support
University of Queensland research has highlighted the need for specialized support services to help people with young onset dementia cope with giving up driving. The research was published in BMC Geriatrics.
January 17th, 2025 — Source

New criteria developed for appropriate use of cognitive impairment imaging tools
Appropriate use criteria (AUC) for the use of amyloid and tau positron emission tomography (PET) have been issued by the Alzheimer's Association and the Society for Nuclear Medicine and Molecular Imaging and published online Jan. 8 in both Alzheimer's & Dementia and the Journal of Nuclear Medicine.
January 17th, 2025 — Source

New diagnostic criteria for LATE dementia offer hope for improved care
Researchers at the University of Kentucky's Sanders-Brown Center on Aging are at the forefront of advancing dementia research with groundbreaking work on a condition known as LATE, or "limbic predominant age-related TDP-43 encephalopathy."
January 17th, 2025 — Source

Health — Alzheimers — January 13th, 2025

Brain connectome phenotype linked to cerebrovascular disease can track cognitive decline
Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.
January 13th, 2025 — Source or Source

Brain degeneration in dementia with Lewy bodies begins early, study shows
DLB is a common cause of dementia. It starts with the abnormal accumulation of the protein alpha-synuclein in the brain. This produces degeneration of the brain and causes problems with thinking, movement, and behavior. Eventually, the disease leads to dementia and death. Doctors use an imaging technique called FDG-PET to assess how the brain is affected in DLB. However, until now, there was no information on how these brain changes develop over time.
January 13th, 2025 — Source

Depression in older adults could signal early dementia, study suggests
Having depression is known to increase a person's risk of developing dementia, but depression is also an early indicator of dementia—particularly in older people—according to new research led by Queen Mary University of London and published in the Journal of Neurology, Neurosurgery & Psychiatry.
January 13th, 2025 — Source

Genetic risk for dementia shapes parenting and family planning choices
Living in a family where there is genetic risk for dementia significantly affects choices about having children and how to parent, finds a new study led by UCL researchers.
January 13th, 2025 — Source

Introducing FDI, the Florey Dementia Index for Alzheimer's onset prediction
A predictive tool for determining the age at which individuals may develop mild cognitive impairment (MCI) or Alzheimer's dementia (AD) has demonstrated the ability to predict MCI onset within 2.78 years and AD onset within 1.48 years.
January 13th, 2025 — Source

Link between gum disease and brain function exists, small study says
Gum disease appears to disrupt brain activity, potentially increasing a person's risk of cognitive decline.
January 13th, 2025 — #2693
#2693
January 13th, 2025 — Source

Survey shows previous experience affects family planning decisions of people with hereditary dementia
Living in a family where there is genetic risk for dementia significantly affects choices about having children and how to parent, finds a study led by UCL researchers.
January 13th, 2025 — Source

Three psychological profiles could determine the evolution of mental, cognitive and brain health in aging
The study, which analyzed more than 1,000 middle-aged and older adults, shows that the specific psychological characteristics of each profile may influence the risk of developing dementia, as well as aspects such as the speed of brain decline and sleep quality. These findings open new perspectives for the design of more personalized prevention strategies.
January 13th, 2025 — Source

U.S. dementia cases expected to surge with aging population
A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.
January 13th, 2025 — Source or Source

Health — Alzheimers — January 9th, 2025

Genetic changes in brain cells link aging and Alzheimer's
Genetic differences that contribute to how long a person will live and their risk of Alzheimer's disease have been identified by researchers at UCL and the UK Dementia Research Institute (UK DRI).
January 9th, 2025 — Source

Dementia diagnosis: How long do patients really live?
The average life expectancy of people diagnosed with dementia ranges from nine years at age 60 to 4.5 years at age 85 for women and from 6.5 to just over two years, respectively, in men, finds a systematic review of the latest evidence in The BMJ.
January 9th, 2025 — Source

Health — Alzheimers — January 8th, 2025

Blood test could help track Alzheimer's disease progression and severity
Declining blood levels of two molecules that occur naturally in the body track closely with worsening Alzheimer's disease, particularly in women. Levels were found to drop gradually, from women with no signs of memory, disorientation, and slowed thinking to those with early signs of mild cognitive impairment. Decreases were more prominent in women with moderate or severe stages of the disease. Declines in men were evident in only one molecule, revealing a disease-specific difference between the sexes.
January 8th, 2025 — Source

Common sleep aid may disrupt system that clears brain waste linked to Alzheimer's
Getting a good night's sleep is a critical part of our daily biological cycle and is associated with improved brain function, a stronger immune system, and a healthier heart. Conversely, sleep disorders like insomnia and sleep apnea can significantly impact health and quality of life. Poor sleep often precedes the onset of neurodegenerative diseases and is a predictor of early dementia.
January 8th, 2025 — Source

Study advances possible blood test for early-stage Alzheimer's disease, explains why women may be at higher risk
Declining blood levels of two molecules that occur naturally in the body track closely with worsening Alzheimer's disease, particularly in women. Levels were found to drop gradually, from women with no signs of memory, disorientation, and slowed thinking to those with early signs of mild cognitive impairment. Decreases were more prominent in women with moderate or severe stages of the disease.
January 8th, 2025 — Source

Health — Alzheimers — January 7th, 2025

Exploring genetic sex differences in Alzheimer's: Scientists investigate duplicate X chromosome impact
An international team of scientists has uncovered new insights into how the previously understudied duplicate X chromosome in women may contribute to Alzheimer's disease risk, according to a multicenter study published in the journal Molecular Psychiatry.
January 7th, 2025 — Source

New evidence links dementia to problems with the brain's waste clearance system
A study from the Keck School of Medicine of USC has tested a biomarker linked to vascular dementia across four separate groups and proposed an explanation for how cognitive impairment arises.
January 7th, 2025 — Source

Health — Alzheimers — January 6th, 2025

Seven tips to help people with dementia during a cold snap
Many parts of the U.K. are facing a dramatic drop in temperature throughout the coming week with the Met Office issuing an amber cold weather alert lasting until 8 January. This cold snap could be challenging for almost 1 million people living with dementia across the U.K.
January 6th, 2025 — Source

Health — Alzheimers — January 3rd, 2025

Addressing barriers to healthcare delivery for people with Alzheimer's disease and related dementias
Kosali Simon, PhD, M.A., a professor with the Paul H. O'Neill School of Public and Environmental Affairs and a Regenstrief Institute research scientist; and Katherine Baicker, PhD, University of Chicago provost, will co-lead an expected nearly $16 million National Institutes of Health's (NIH) National Institute on Aging (NIA) program to explore critical aspects of healthcare delivery for individuals living with Alzheimer's disease and related dementias (ADRD).
January 3rd, 2025 — Source

Exploring avoidable nursing home-to-hospital transfers for dementia patients
For many nursing home residents, a trip to the hospital can be a jarring experience -; one that leaves them confused and stressed. Yet avoidable transfers happen far too often, not only disrupting a resident's routine but also costing the U.S. healthcare system $2.6 billion annually.
January 3rd, 2025 — Source

Prevalence of dementia diagnoses increased in individuals with autism diagnosis
Individuals with an autism spectrum disorder (ASD) diagnosis have an increased prevalence of identified dementia diagnoses, according to a research letter published online Jan. 2 in JAMA Network Open.
January 3rd, 2025 — Source

Researchers aim to reduce avoidable hospitalizations for nursing home residents with dementia
For many nursing home residents, a trip to the hospital can be a jarring experience—one that leaves them confused and stressed. Yet avoidable transfers happen far too often, not only disrupting a resident's routine but also costing the U.S. health care system $2.6 billion annually.
January 3rd, 2025 — Source

Study shows 'good' cholesterol may protect against brain atrophy, dementia
High-density lipoprotein (HDL), or "good" cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report. The findings, published in the Journal of Clinical Medicine, could give doctors and patients more insight into factors that affect cognitive health in aging adults.
January 3rd, 2025 — Source

Syringe exchange fears hobble fight against West Virginia HIV outbreak
More than three years have passed since federal health officials arrived in central Appalachia to assess an alarming outbreak of HIV spread mostly between people who inject opioids or methamphetamine.
January 3rd, 2025 — Source

Unlocking proteostasis: A new frontier in the fight against neurodegenerative diseases like Alzheimer's
Scientists have uncovered a powerful ally in the fight against neurodegenerative diseases: a nucleolar complex that plays a pivotal role in maintaining cellular health through protein homeostasis (proteostasis), by which cells maintain the balance and proper functioning of their proteins.
January 3rd, 2025 — Source

Health — Alzheimers — December 27th, 2024

Study reveals how societal inequities influence brain aging and dementia
Researchers from Trinity College Dublin have collaborated with international partners to explore if societal inequality affects our brain. Their research paper is published in Nature Aging today, [Friday, December 27th] by an international team of researchers from the Multipartner Consortium to expand dementia research in Latin America (ReDLat), the Latin American Brain Health Institute (BrainLat), the GIobal Brain Health Institute (GBHI) at Trinity College Dublin, and other centres across the globe.
December 27th, 2024 — Source

Societal inequality linked to reduced brain health in aging and dementia
Researchers from Trinity College Dublin have collaborated with international partners to explore if societal inequality affects the brain.
December 27th, 2024 — Source

Health — Alzheimers — December 20th, 2024

How to boost your brain health
Can simple diet and lifestyle changes keep your brain healthy? Do you have the power to prevent Alzheimer's disease and dementia or lower your MS risks?
December 20th, 2024 — Source

Health — Alzheimers — December 16th, 2024

Hepatitis C in Australia has more than halved in less than a decade, says report
In 2023, there were an estimated 68,890 people living with hepatitis C in Australia, down 58% from 162,590 at the end of 2015, according to a new report released by the Kirby Institute at UNSW Sydney.
December 16th, 2024 — Source

How to keep life engaging for people with Alzheimer's
Adapting activities for individuals with Alzheimer's disease is essential for maintaining their engagement and well-being. As Alzheimer's progresses, activities that were once routine can become challenging. Here's how caregivers can help loved ones enjoy meaningful and fulfilling experiences.
December 16th, 2024 — Source

Reading books over watching TV linked to lower dementia risk
It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV control, or a favorite book, your choice could have implications for your long-term brain health, say researchers at the University of South Australia.
December 16th, 2024 — Source

Health — Alzheimers — December 13th, 2024

Microglia: The double-edged sword in Alzheimer's progression
Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & Disease have unraveled the varying roles of microglia in Alzheimer's at different stages of the disease.
December 13th, 2024 — Source

You can't remember what you can't hear: The hearing loss, brain-health link
Humans by nature are social. People enjoy being with others, sharing stories, laughing at a joke, dancing to a favorite song, greeting a neighbor, discussing concerns or offering consolation. These connections, whether close or casual, are essential to emotional well-being and brain health.
December 13th, 2024 — Source

Health — Alzheimers — December 10th, 2024

Detailed mapping shows how astrocytes change throughout the progression of Alzheimer's disease
Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain barrier, and contribute to brain repair and homeostasis. The evolution of these cells throughout the progression of Alzheimer's disease (AD) is still poorly understood, particularly when compared to that of neurons and other cell types.
December 10th, 2024 — Source

Does menopause hormone therapy increase or decrease your risk of dementia? Here's the science
By 2050, around 135 million people worldwide will be living with dementia. The most common cause of dementia is Alzheimer's disease. Women are more likely than men to develop Alzheimer's disease, even after accounting for women living longer.
December 10th, 2024 — Source

New study highlights how musical interactions can support relationships for people living with dementia
More than 982,000 individuals in the U.K. are currently living with dementia, a condition that gradually erodes cognitive functions and can significantly impact daily life.
December 10th, 2024 — Source

Portable MRI shows promise for expanding brain imaging for Alzheimer's disease
Globally, approximately 139 million people are expected to have Alzheimer's disease (AD) by 2050. Magnetic resonance imaging (MRI) is an important tool for identifying changes in brain structure that precede cognitive decline and progression with disease; however, its cost limits widespread use.
December 10th, 2024 — Source

Health — Alzheimers — December 6th, 2024

Network-based analyses uncover how neuroinflammation-causing microglia in Alzheimer's disease form
Cleveland Clinic Genome Center researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study, published in the journal Alzheimer's & Dementia, also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target disease-associated microglia in Alzheimer's disease without affecting the healthy type.
December 6th, 2024 — Source

New insights into Niemann-Pick type C: A form of childhood dementia
In an article published in the journal Science Translational Medicine, scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.
December 6th, 2024 — Source or Source

Stroke survivors face much higher odds for dementia, research finds
Stroke survivors have an 80% increased risk of dementia compared to people who've never suffered a stroke, a new study finds.
December 6th, 2024 — Source

Health — Alzheimers — December 2nd, 2024

Discontinuing cholinesterase when starting memantine not tied to institutionalization care
Discontinuing cholinesterase inhibitors upon memantine initiation is not associated with an increased risk for long-term care institutionalization among older adults with dementia, according to a study published online Nov. 19 in JAMA Network Open.
December 2nd, 2024 — Source

Ketone esters help clear misfolded proteins in mouse model of aging and Alzheimer's disease
Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best be understood as powerful signaling metabolites affecting brain function in aging and Alzheimer's disease.
December 2nd, 2024 — Source or Source

Study highlights the critical role of TLR7 in sex-biased Alzheimer's-related demyelination
Inhibiting an immune signaling protein called TLR7 may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine.
December 2nd, 2024 — Source

Visceral fat found to contribute to Alzheimer's disease development
Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA). The researchers emphasized that lifestyle modifications targeted at reducing this fat could influence the development of Alzheimer's disease.
December 2nd, 2024 — Source

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