Health — Alzheimers — December 20th, 2024

How to boost your brain health
Can simple diet and lifestyle changes keep your brain healthy? Do you have the power to prevent Alzheimer's disease and dementia or lower your MS risks?
December 20th, 2024 — Source

Health — Alzheimers — December 16th, 2024

Hepatitis C in Australia has more than halved in less than a decade, says report
In 2023, there were an estimated 68,890 people living with hepatitis C in Australia, down 58% from 162,590 at the end of 2015, according to a new report released by the Kirby Institute at UNSW Sydney.
December 16th, 2024 — Source

How to keep life engaging for people with Alzheimer's
Adapting activities for individuals with Alzheimer's disease is essential for maintaining their engagement and well-being. As Alzheimer's progresses, activities that were once routine can become challenging. Here's how caregivers can help loved ones enjoy meaningful and fulfilling experiences.
December 16th, 2024 — Source

Reading books over watching TV linked to lower dementia risk
It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV control, or a favorite book, your choice could have implications for your long-term brain health, say researchers at the University of South Australia.
December 16th, 2024 — Source

Health — Alzheimers — December 13th, 2024

Microglia: The double-edged sword in Alzheimer's progression
Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & Disease have unraveled the varying roles of microglia in Alzheimer's at different stages of the disease.
December 13th, 2024 — Source

You can't remember what you can't hear: The hearing loss, brain-health link
Humans by nature are social. People enjoy being with others, sharing stories, laughing at a joke, dancing to a favorite song, greeting a neighbor, discussing concerns or offering consolation. These connections, whether close or casual, are essential to emotional well-being and brain health.
December 13th, 2024 — Source

Health — Alzheimers — December 10th, 2024

Detailed mapping shows how astrocytes change throughout the progression of Alzheimer's disease
Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain barrier, and contribute to brain repair and homeostasis. The evolution of these cells throughout the progression of Alzheimer's disease (AD) is still poorly understood, particularly when compared to that of neurons and other cell types.
December 10th, 2024 — Source

Does menopause hormone therapy increase or decrease your risk of dementia? Here's the science
By 2050, around 135 million people worldwide will be living with dementia. The most common cause of dementia is Alzheimer's disease. Women are more likely than men to develop Alzheimer's disease, even after accounting for women living longer.
December 10th, 2024 — Source

New study highlights how musical interactions can support relationships for people living with dementia
More than 982,000 individuals in the U.K. are currently living with dementia, a condition that gradually erodes cognitive functions and can significantly impact daily life.
December 10th, 2024 — Source

Portable MRI shows promise for expanding brain imaging for Alzheimer's disease
Globally, approximately 139 million people are expected to have Alzheimer's disease (AD) by 2050. Magnetic resonance imaging (MRI) is an important tool for identifying changes in brain structure that precede cognitive decline and progression with disease; however, its cost limits widespread use.
December 10th, 2024 — Source

Health — Alzheimers — December 6th, 2024

Network-based analyses uncover how neuroinflammation-causing microglia in Alzheimer's disease form
Cleveland Clinic Genome Center researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study, published in the journal Alzheimer's & Dementia, also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target disease-associated microglia in Alzheimer's disease without affecting the healthy type.
December 6th, 2024 — Source

New insights into Niemann-Pick type C: A form of childhood dementia
In an article published in the journal Science Translational Medicine, scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.
December 6th, 2024 — Source or Source

Stroke survivors face much higher odds for dementia, research finds
Stroke survivors have an 80% increased risk of dementia compared to people who've never suffered a stroke, a new study finds.
December 6th, 2024 — Source

Health — Alzheimers — December 2nd, 2024

Discontinuing cholinesterase when starting memantine not tied to institutionalization care
Discontinuing cholinesterase inhibitors upon memantine initiation is not associated with an increased risk for long-term care institutionalization among older adults with dementia, according to a study published online Nov. 19 in JAMA Network Open.
December 2nd, 2024 — Source

Ketone esters help clear misfolded proteins in mouse model of aging and Alzheimer's disease
Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best be understood as powerful signaling metabolites affecting brain function in aging and Alzheimer's disease.
December 2nd, 2024 — Source or Source

Study highlights the critical role of TLR7 in sex-biased Alzheimer's-related demyelination
Inhibiting an immune signaling protein called TLR7 may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine.
December 2nd, 2024 — Source

Visceral fat found to contribute to Alzheimer's disease development
Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA). The researchers emphasized that lifestyle modifications targeted at reducing this fat could influence the development of Alzheimer's disease.
December 2nd, 2024 — Source

Health — Alzheimers — November 29th, 2024

Experts call for responsible messaging on hearing loss and dementia
The U.K.'s leading hearing loss organizations have joined forces to highlight misleading reports by some health professionals and the media that hearing loss causes dementia, and treating hearing loss will reduce our individual risk of dementia.
November 29th, 2024 — Source

Health — Alzheimers — November 27th, 2024

'Alzheimer's in dish' model shows promise for accelerating drug discovery
A new algorithm has determined that 3D models using mature brain cells accurately mimic the brain biology seen in human patients, allowing researchers to test multiple drugs at once and informing predictions about drug targets and therapies
November 27th, 2024 — Source or Source

Disruption of mechanical signaling in brain could be basis for development of Alzheimer's disease, study proposes
A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease. Researchers have shed new light on how mechanical signaling in the brain is disrupted and could lead to the condition, which accounts for 60%--80% of dementia cases worldwide.
November 27th, 2024 — Source

Holiday travel with a loved one with dementia: An expert offers tips
Thanksgiving travel is a must for millions of Americans, but those plans will be complicated for some because they're traveling with a loved one who has Alzheimer's disease or dementia.
November 27th, 2024 — Source

New discovery could offer significant answers on Alzheimer's disease
A new study represents a significant step forward in scientists' understanding of Alzheimer's disease. A team of investigators has examined the role of two proteins found in the brain and suggest the stability of their relationship to one another is crucial for memory formation and maintenance. Disruptions in this mechanical signalling pathway could lead to the disease.
November 27th, 2024 — Source

Study unveils key mechanism in Alzheimer's disease
A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease.
November 27th, 2024 — Source

Health — Alzheimers — November 25th, 2024

Brain shrinkage associated with Alzheimer's immunotherapies may show effectiveness rather than harm
A loss of brain volume associated with new immunotherapies for Alzheimer's disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a study led by UCL researchers.
November 25th, 2024 — Source

Brain volume loss linked to Alzheimer's treatment may be caused by amyloid plaque removal
A loss of brain volume associated with new immunotherapies for Alzheimer's disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a study led by UCL researchers.
November 25th, 2024 — Source

Nasal spray drug shows promise in Alzheimer's research
A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the disease.
November 25th, 2024 — Source

New study offers insights into reliable Alzheimer's diagnosis
A research group at LMU University Hospital has investigated how Alzheimer's disease can be diagnosed more reliably in the future.
November 25th, 2024 — Source

Vulnerability to financial scams in aging adults could be early indicator of Alzheimer's disease
A brain region affected very early in Alzheimer's disease may explain why some aging people are at greater risk of financial exploitation. That is the key finding of our new study, published in the journal Cerebral Cortex.
November 25th, 2024 — Source

Health — Alzheimers — November 21st, 2024

Centiloid guidelines and recommendations released for clinical context-of-use in Alzheimer's disease
The members of the Amyloid imaging to prevent Alzheimer's disease (AMYPAD) have announced the publication of a perspective review on the interpretability and clinical application of the Centiloid (CL) scale, a robust method for measuring amyloid plaques in the brain, a key hallmark of Alzheimer's disease (AD).
November 21st, 2024 — Source

Cerebral small vessel disease marker validated for wider use in dementia trials
A new neuroimaging marker of cerebral small vessel disease is related to general cognition and may serve to identify persons at risk of dementia in future clinical trials, a landmark study has found.
November 21st, 2024 — Source

Presence of white spots on MRI brain scans linked to genetic risk of dementia in older adults
They show up as bright white spots when you get a brain MRI: lesions called white matter hyperintensities, or WMH. And their presence suggests something may be wrong with your brain's white matter—there could be structural abnormalities.
November 21st, 2024 — Source

Signals of inflammation during pregnancy linked to aging and memory changes 50 years later
An estimated 13.8 million people in the U.S. will have Alzheimer's disease (AD) by 2050, two thirds of whom are projected to be women. The brain circuitry underlying memory is widely known to differ based on biological sex, but sex-based drivers of aging and AD are still unclear.
November 21st, 2024 — Source

Study links prenatal immune activity to Alzheimer's risk in later life
Findings from a Mass General Brigham-led study that has followed participants since before birth may offer clues about the origins of Alzheimer's disease.
November 21st, 2024 — Source

Health — Alzheimers — November 18th, 2024

Quick finger prick could soon make Alzheimer's testing much more accessible
A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon make Alzheimer's testing much more accessible worldwide. A European study led by researchers at the University of Gothenburg, Sweden, is paving the way for this method.
November 18th, 2024 — Source

What is 'doll therapy' for people with dementia? And is it backed by science?
The way people living with dementia experience the world can change as the disease progresses. Their sense of reality or place in time can become distorted, which can cause agitation and distress.
November 18th, 2024 — Source

Health — Alzheimers — November 15th, 2024

New drug targets for Alzheimer's identified from cerebrospinal fluid
Study pegs certain cellular activities to driving Alzheimer's disease
November 15th, 2024 — Source

Health — Alzheimers — November 12th, 2024

Cognitive decline and loneliness linked in older adults over short time periods
For years, research has shown that older adults who are lonely are at greater risk for cognitive decline and conditions like Alzheimer's disease. Those studies, however, generally treated loneliness as a stable trait of someone's life, but loneliness fluctuates from day to day and even over the course of a single day.
November 12th, 2024 — Source

TYK2 inhibition may offer new strategy to reduce tau toxicity in Alzheimer's
Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions discovered that the enzyme TYK2 transforms the normal protein tau into one that accumulates in the brain and contributes to the development of Alzheimer's disease in animal models. Published in Nature Neuroscience, the study suggests that partially restraining TYK2 could be a strategy to reduce tau levels and toxicity.
November 12th, 2024 — Source

Health — Alzheimers — November 8th, 2024

New study links genetic mosaicism to lower Alzheimer's risk in adults with Down syndrome
Researchers identified mosaicism as a possible factor influencing Alzheimer's risk in adults with Down syndrome, offering new insights into amyloid biomarkers and their broader implications for the general population.
November 8th, 2024 — Source

Slow-Wave Sleep Essential to Staving Off Dementia: Study
Losing even a little bit of slow-wave sleep on a consistent basis could raise your risk of dementia by 27%.
November 8th, 2024 — Source

Study highlights challenges of reducing risky drugs in Alzheimer's patients
Can large national health plans make an impact in reducing prescribing of high-risk medications to people with Alzheimer's disease or related dementias by mailing patients, caregivers and their health care providers educational materials?
November 8th, 2024 — Source

Traditional Chinese herb shows promise against Alzheimer's and Parkinson's
Study finds Zizyphi spinosi semen may reduce brain aging and improve cognitive function in neurodegenerative disease models.
November 8th, 2024 — Source

Health — Alzheimers — November 7th, 2024

Nasal spray made from stem cell-derived vesicles could treat Alzheimer's diseaseA new therapy may delay Alzheimer's disease progression by years, according to a study by researchers at Texas A&M University College of Medicine. Published in the Journal of Extracellular Vesicles, the research aims to explore treatment options for Alzheimer's, which constitutes the most common form of dementia and is a leading cause of death among those aged 65 or older, afflicting nearly 7 million Americans.
#2693
November 7th, 2024 — Source

Poor sleep quality linked to incident motoric cognitive risk syndrome
Poor sleep quality may be associated with incidental, but not prevalent, motoric cognitive risk syndrome (MCR), a predementia syndrome characterized by slow gait speed and cognitive complaints, according to a study published online Nov. 6 in Neurology.
November 7th, 2024 — Source

Unrecognized cognitive impairment in vulnerable older adults is ubiquitous, says study
One of the first studies to investigate the prevalence of unrecognized cognitive impairment among patients seen at Federally Qualified Health Centers, has found that it is ubiquitous, especially among minoritized older adults. These facilities provide primary care and preventive services regardless of ability to pay or health insurance status to more than 30 million patients, including a growing number of older adults.
November 7th, 2024 — Source

Health — Alzheimers — November 5th, 2024

AI-based dementia prediction technology uses automatic speech recognition
Researchers in South Korea have developed an AI-based technology that can analyze the voice/speech of the elderly to screen and detect those who are at high risk of mild cognitive impairment and dementia.
November 5th, 2024 — Source

Alzheimer's and alcohol use disorder found to share similar gene expression patterns
Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, epidemiological studies suggest that lifestyle factors including alcohol use could also impact disease onset and progression.
November 5th, 2024 — Source

New criteria to avoid the over-diagnosis of Alzheimer's disease
Diagnosis of Alzheimer's disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted. To counter this problem, a global expert panel led by Hôpitaux universitaires de Genève (HUG), the University of Geneva and the Salpêtrière Hospital have drawn up recommendations.
November 5th, 2024 — Source

Revised diagnostic criteria seek to avoid over-diagnosis of Alzheimer's disease
Diagnosis of Alzheimer's Disease (AD) is currently largely based on the presence of biomarkers. This may lead to a problematic over-diagnosis if this is incorrectly interpreted.
November 5th, 2024 — Source

Health — Alzheimers — November 1st, 2024

Precision diagnostics close in on Parkinson's disease proteins in extracellular vesicles
Brain disorders like Parkinson's disease (PD) or Alzheimer's disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages. Thus far, the specific brain lesions caused by PD, for example, can only be detected by analyzing brain biopsies, which can only be obtained posthumously.
November 1st, 2024 — Source

Study links obstructive sleep apnea to increased dementia risk in women
A common yet underdiagnosed sleep disorder contributes to the development of dementia among adults -; particularly women, a Michigan Medicine study suggests.
November 1st, 2024 — Source

Study shows how education, occupation and wealth affect the risk of cognitive impairment
Socioeconomic factors such as education, occupation, and wealth influence the likelihood of developing cognitive impairment or dementia in later life and whether a person is likely to recover, finds a new study led by UCL researchers.
November 1st, 2024 — Source

Health — Alzheimers — October 28th, 2024

Alzheimer's research: Superspreader fibrils caught in the act

The treatment of dementia disorders such as Alzheimer's is still one of the greatest challenges facing modern medicine. In the course of neurodegenerative diseases, certain proteins such as the amyloid &beta protein accumulate in the brain. They are suspected of being linked to the development of the disease, which is why they are considered a promising target for therapeutic approaches.
October 28th, 2024 — Source

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

In this interview conducted at the Society for Neuroscience 2024 conference, Heather Snyder, Senior Vice President of Medical and Scientific Relations at the Alzheimer's Association, discusses the Association's key research initiatives, breakthroughs in Alzheimer's diagnostics and treatment, and the vital role of collaboration and public awareness in advancing the fight against dementia.
October 28th, 2024 — Source

Health — Alzheimers — October 25th, 2024

Semaglutide may reduce Alzheimer's risk in diabetics
Semaglutide linked to 40-70% lower risk of first-time Alzheimer's diagnosis in type 2 diabetes patients compared to other antidiabetic medications.
October 25th, 2024 — Source

Health — Alzheimers — October 22nd, 2024

Bilingualism may maintain protection against Alzheimer's, neuroimaging study finds
Bilingualism has long been known to have cognitive benefits for older adults. Research shows it helps delay the onset of Alzheimer's disease by up to five years compared to monolingual adults. This is one of several lifestyle factors that may contribute to brain resilience as we age.
October 23rd, 2024 — Source or Source

Brain blood flow resistance more common in older adults with cognitive problems
Older adults with mild cognitive impairment showed greater resistance to brain blood flow compared to those without cognitive impediments. The first-of-its-kind study is published in the Journal of Applied Physiology.
October 23rd, 2024 — Source

Health — Alzheimers — October 20th, 2024

Alzheimer's disease may damage the brain in two phases
Alzheimer's disease may damage the brain in two distinct phases, based on new research using sophisticated brain mapping tools. According to researchers who discovered this new view, the first, early phase happens slowly and silently—before people experience memory problems—harming just a few vulnerable cell types. In contrast, the second, late phase causes damage that is more widely destructive and coincides with the appearance of symptoms and the rapid accumulation of plaques, tangles, and other Alzheimer's hallmarks.
October 20th, 2024 — Source

Health — Alzheimers — October 18th, 2024

New study reveals molecular mechanism in Alzheimer's disease
A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer's patients. The study, which has been carried out in post-mortem samples of patients and in animal models of the disease, will boost the design of future therapies to address the treatment of this dementia and other neurological disorders.
October 18th, 2024 — Source

Researchers Develop Eye Scanner That Spots Signs of Diabetes, Heart Disease, Alzheimer's
One eye scanner to detect them all.
October 18th, 2024 — Source

Researchers identify molecular mechanism that could help design future therapies to treat Alzheimer's disease
A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer's patients.
October 18th, 2024 — Source

Solving a 50-year-old mystery could lead to neurodegenerative disease treatments
Scientists have gained a deeper understanding of a molecule that regulates lipid levels in the brain. This breakthrough could eventually lead to treatments for diseases like frontotemporal dementia and Alzheimer's disease.
October 18th, 2024 — Source

The molecular underpinnings by which traumatic brain injury increases Alzheimer's disease risk
Researchers found that traumatic brain injury increases synaptic dysfunction and cognitive impairments linked to developing Alzheimer's disease.
October 18th, 2024 — Source

Health — Alzheimers — October 12th, 2024

Targeting hippocampal neurons to unlock existing Alzheimer's drugs
A team of researchers at Kobe Gakuin University in Japan have genetically engineered insulin-fused proteins capable of targeting hippocampal neurons. The innovative technique capitalizes on insulin's natural tendency to accumulate in the hippocampal neuronal tissue. This new approach could unlock existing treatments for neurodegenerative disorders such as Alzheimer's disease by allowing existing drugs to be delivered on target.
October 12th, 2024 — Source

Health — Alzheimers — October 11th, 2024

High-density lipoproteins quality, not quantity, contribute to the first sign of Alzheimer's disease in women
Higher levels of HDL-C—known as the "good cholesterol"—have been shown to correlate with heightened risk for Alzheimer's disease. A new study published in the Journal of Clinical Endocrinology & Metabolism might explain why.
October 11th, 2024 — Source

Health — Alzheimers — October 10th, 2024

Heart failure, atrial fibrillation and coronary heart disease linked to cognitive impairment
Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the journal, Stroke.
October 10th, 2024 — Source

Loneliness increases dementia odds by 31%, study finds
A new study finds persistent loneliness taking a toll on aging brains and significantly raising a person's odds for dementia.
October 10th, 2024 — Source

Health — Alzheimers — October 8th, 2024

Brain network study reveals clues about dementia's behavior changes
Tau protein buildup in brain disrupts the salience network that connects multiple brain regions and helps us react to the outside world and our own thoughts
October 8th, 2024 — Source

Health — Alzheimers — October 7th, 2024

Brain network study reveals clues about dementia's behavior changes
When most people think of dementia, including Alzheimer's disease, they probably think of memory loss first. But dementia also changes the way a person behaves, whether it makes them quick to get angry or distressed, causes them to become depressed, anxious or apathetic, or even changes their whole personality.
October 7th, 2024 — Source

Imaging in neurosurgery patients reveals the brain's waste-clearance pathways for the first time
Scientists have long theorized about a network of pathways in the brain that are believed to clear metabolic proteins that would otherwise build up and potentially lead to Alzheimer's and other forms of dementia. But they had never definitively revealed this network in people—until now.
October 7th, 2024 — Source

Health — Alzheimers — September 25th, 2024

New Health Tech Aims to Reduce the Gap in Dementia Detection
Seven in ten dementia cases go undetected, leaving millions of patients in a vulnerable situation. But it is not a lack of access to healthcare and care facilities that drives this statistic. Experts say that traditional dementia diagnostic tests don't have the subtlety needed for early diagnosis.
September 25th, 2024 — Source

Health — Alzheimers — September 23rd, 2024

Astrocytes study identifies a new therapeutic target for Alzheimer's disease
Worldwide, at least 50 million people are believed to be living with a form of dementia. Alzheimer's disease is the most common type of dementia. It is a progressive and irreversible neurodegenerative disorder that primarily affects memory and cognitive functions. Symptoms include memory loss that disrupts daily life, poor judgment and taking longer to complete normal daily tasks. There is currently no cure.
September 23rd, 2024 — Source

Health — Alzheimers — September 19th, 2024

Flavonoid consumption may reduce the risk of dementia, new study shows/span>
New research has found that those who consume more foods rich in flavonoids, such as berries, tea, red wine and dark chocolate, could lower their risk of dementia.
September 19th, 2024 — Source

Health — Alzheimers — September 16th, 2024

AI-based tissue staining can detect amyloid deposits without chemical stains or polarization microscopy
Researchers at the University of California, Los Angeles (UCLA) have pioneered a groundbreaking approach in the imaging and detection of amyloid deposits in tissue samples. The innovative method leverages deep learning and autofluorescence microscopy to achieve virtual birefringence imaging and histological staining, eliminating the need for polarization imaging and traditional chemical stains like Congo red.
September 16th, 2024 — Source

Health — Alzheimers — September 14th, 2024

Researchers seek early Alzheimer's detection with MRSI
University of Virginia professor Mathews Jacob has secured a $3.9 million grant to advance his innovative research on detecting Alzheimer's disease in its early stages. Jacob, who specializes in electrical and computer engineering, is teaming up with researchers from the University of Iowa and the University of California-San Francisco to push the boundaries of imaging technology that tracks the brain's metabolic changes -; offering a fresh perspective on studying neurodegenerative disorders.
September 14th, 2024 — Source

Health — Alzheimers — September 13th, 2024

New therapy that targets and destroys tau tangles: A promising Alzheimer's disease treatment
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
September 13th, 2024 — Source

Health — Alzheimers — September 10th, 2024

Study finds link between nighttime light exposure and increased Alzheimer's disease risk
Startling new study reveals nighttime light pollution may spike Alzheimer's risk, with younger adults most affected.
September 10th, 2024 — Source

Trauma exposure accelerates brain aging which can lead to Alzheimer's disease, study suggests
As the median age of our population rises, so does the number of people diagnosed with Alzheimer's disease. With advances in technology, it's easier to determine brain age and identify blood-based Alzheimer's disease biomarkers.
September 10th, 2024 — Source

Health — Alzheimers — September 9th, 2024

Alzheimer's study: Drug combination improves memory skills in mice
Laboratory mice with cognitive issues including Alzheimer's disease showed improved memory skills within a couple of weeks of treatment with a new medicine tested at Colorado State University.
September 9th, 2024 — Source

Health — Alzheimers — September 6th, 2024

Alzheimer's study reveals critical differences in memory loss progression based on the presence of specific proteins
A study from Karolinska Institutet, published in the journal Molecular Psychiatry, offers new insights into the progression of Alzheimer's disease (AD). The research reveals critical differences in the progression of memory loss based on the presence of specific proteins in the brain.
September 6th, 2024 — Source

Cognitive training sessions helps seniors cope with memory loss, study finds
Can training your brain to remember things help you ward off the symptoms of Alzheimer's disease? A new Canadian study suggests that yes, it can—even five years after you received the training.
September 6th, 2024 — Source

Study of older patients suggests 1 in 5 cases of dementia may be attributable to vision impairment
Prior research has found that there may be a connection between hearing loss in aging people and the onset of dementia. In a new study, a team of health care researchers and geriatric specialists affiliated with Johns Hopkins Bloomberg School of Public Health, the University of Michigan and the Duke University School of Medicine surveyed patient health care records and reported that approximately 1 in 5 cases of dementia could also be attributable to vision impairment in community-dwelling U.S. adults aged 71 years or older.
September 6th, 2024 — Source

Study uncovers critical biomarker differences, advocates for more inclusive Alzheimer's diagnostics
The Emory Goizueta Brain Health Institute (GBHI) has prioritized involving African American volunteers in its research, working to create more inclusive tools for diagnosing Alzheimer's disease and related disorders. Today, about half of the Institute's new volunteers are African American.
September 6th, 2024 — Source

Health — Alzheimers — September 2nd, 2024

Researchers pinpoint key gene mutations, new mechanisms that cause brain bleeding and dementia
Scientists have revealed new insights into the mechanisms behind cerebral small vessel disease, a condition that affects the smaller blood vessels in the brain and causes approximately half of all dementia cases.
September 2nd, 2024 — Source

Health — Alzheimers — August 27th, 2024

Dementia Australia welcomes UK approval of lecanemab to tackle Alzheimer's
Dementia Australia welcomes the decision by the Medicines and Healthcare Products Regulatory Agency to approve Lecanemab for use in the UK.
August 27th, 2024 — Source

FDA-approved Alzheimer's drug induces torpor-like state in tadpoles
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer's.
August 27th, 2024 — Source

Risk for dementia found to be similar with SGLT2 inhibitors, dulaglutide in type 2 diabetes
For older adults with type 2 diabetes, the risk for dementia seems similar with sodium-glucose cotransporter 2 (SGLT2) inhibitors and the glucagon-like peptide 1 receptor agonist (GLP-1 RA) dulaglutide, according to a study published online Aug. 27 in the Annals of Internal Medicine.
August 27th, 2024 — Source

Health — Alzheimers — August 22nd, 2024

Alzheimer's drug may someday help save lives by inducing a state of 'suspended animation'
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University report that they were able to successfully put tadpoles of Xenopus laevis frogs into a hibernation-like torpor state using donepezil (DNP), a drug approved by the FDA to treat Alzheimer's.
August 22nd, 2024 — Source

Egg consumption linked to slower cognitive decline in women
In a recent study published in Nutrients, researchers investigated the effects of egg consumption on cognitive function in older adults.
August 22nd, 2024 — Source

New study reveals dopamine analog CA140 mitigates Alzheimer's disease pathology
The small molecule dopamine analog (DA) CA140, which binds to Amyloid-β (Aβ), presents new possibilities for the treatment of degenerative brain diseases.
August 22nd, 2024 — Source

UK drug regulator approves Alzheimer's drug but government likely won't pay for it
Britain's drug regulator authorized the Alzheimer's drug Leqembi on Thursday, saying it's the first medicine to show some impact in slowing the progression of the neurodegenerative disease.
August 22nd, 2024 — Source

Health — Alzheimers — August 21st, 2024

Discovery of 'item memory' brain cells offers new Alzheimer's treatment target
Researchers from the University of California, Irvine have discovered the neurons responsible for "item memory," deepening our understanding of how the brain stores and retrieves the details of "what" happened and offering a new target for treating Alzheimer's disease.
August 21st, 2024 — Source

Promising peptide compound can decrease appetite and protect the brain against Alzheimer's-type diseases
Scientists on the team of Dr. Lenka Maletínská have developed a promising new compound derived from one of the peptides naturally occurring in the brain. Its application may address two major health challenges: obesity and Alzheimer's disease.
August 21st, 2024 — Source

Health — Alzheimers — August 16th, 2024

National study shows varying ability across US to get Alzheimer's or other dementia diagnosis
With new medications on the market or in the works for Alzheimer's disease and other kinds of dementia, a new study suggests that getting the diagnosis needed to access these new treatments may depend on where you live.
August 16th, 2024 — Source

Same person, Different place: Twice the odds of a dementia diagnosis
With new medications on the market or in the works for Alzheimer's disease and other kinds of dementia, a new study suggests that getting the diagnosis needed to access these new treatments may depend on where you live.
August 16th, 2024 — Source

Health — Alzheimers — August 14th, 2024

Alzheimer's cognitive decline predicted by patient's age, sex and irregular heart rhythm
Older age, female sex, irregular heart rhythms, and daily activity levels can help to predict how much Alzheimer's disease patients' cognitive function will decline, and how much they will depend on their caregivers over the next two years.
August 14th, 2024 — Source

Is it OK to lie to someone with dementia?
There was disagreement on social media recently after a story was published about an aged care provider creating "fake-away" burgers that mimicked those from a fast-food chain, to a resident living with dementia.
August 14th, 2024 — Source

Scientists target amyloid beta molecule in search for preventive treatment strategy for Alzheimer's
In the fight against Alzheimer's, researchers at the Technical University of Munich (TUM) have developed a promising, preventative therapeutic approach. They specifically targeted the amyloid beta biomolecule, which triggers the hyperactivity of nerve cells typical of the brain disease in its early stages.
August 14th, 2024 — Source

Health — Alzheimers — August 8th, 2024

Memory loss in aging and dementia: Dendritic spine head diameter predicts memory in old ageOver the course of life, memory fades with varying degrees, robbing older people of the ability to recollect personal experiences. This progressive, nearly inevitable process has long been hypothesized as a consequence of nature's removal of dendritic spines, a key component of synapses, from brain neurons as they age.

August 8th, 2024 — Source

Molecule restores cognition, memory in Alzheimer's disease model mice
In a study, published in the journal The Proceedings of the National Academy of Sciences, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer's disease by effectively jump-starting the brain's memory circuitry.
August 8th, 2024 — Source

Health — Alzheimers — August 3rd, 2024

Can targeted therapies be applied to patients with Alzheimer's?
Alzheimer's disease, a debilitating brain disorder with limited treatment options, has long challenged researchers. Specifically, researchers have struggled with slowing the buildup of amyloid beta plaques, harmful clumps of proteins that exacerbate the disease by damaging brain cells and causing memory loss.
August 3rd, 2024 — Source

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors
Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, according to a new report led by UCL researchers.
August 3rd, 2024 — Source

Health — Alzheimers — August 2nd, 2024

Mouth and dental care for people with dementia often overlooked, study finds
An England-wide study has found the health of people's mouths and teeth is often overlooked by home care services.
August 2nd, 2024 — Source

Novel sequencing approaches highlight role of brain gene activity in Alzheimer's disease
Innovative new research has revealed that the activity of different versions of genes expressed in the brain is associated with the accumulation of the protein tau, which is a hallmark of Alzheimer's disease.
August 2nd, 2024 — Source

Health — Alzheimers — July 31st, 2024

AI boosts the power of EEGs, enabling neurologists to quickly, precisely pinpoint signs of dementia
Mayo Clinic scientists are using artificial intelligence (AI) and machine learning to analyze electroencephalogram (EEG) tests more quickly and precisely, enabling neurologists to find early signs of dementia among data that typically go unexamined.
July 31st, 2024 — Source

Blood proteins may help to track the pathological progression of Lewy body disease
Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-&beta (A&beta) and phosphorylated tau (p-tau) proteins. Researchers at Nagoya University in Japan have also discovered that the blood levels of neurofilament light chain (NfL) protein are elevated at an early stage of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). This discovery may provide a method to identify potential patients and to make early interventions.
July 31st, 2024 — Source or Source

Improving Alzheimer's disease imaging, with fluorescent sensors
Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's. However, the protective blood-brain barrier (BBB) makes delivering fluorescent sensors that can detect these small molecules to the brain difficult.
July 31st, 2024 — Source or Source

Health — Alzheimers — July 29th, 2024

Blood test 91% accurate at predicting Alzheimer's, outperforming doctors
A new test gauging levels of key proteins in the blood was far more accurate than doctor assessments in spotting Alzheimer's disease in people with early-stage illness.
July 29th, 2024 — Source

Blood tests for Alzheimer's may be coming to your doctor's office. Here's what to know
New blood tests could help doctors diagnose Alzheimer's disease faster and more accurately, researchers reported Sunday—but some appear to work far better than others.
July 29th, 2024 — Source

Q&A: Signs that cognitive changes are worrisome — and what you can do about it
Amid ongoing conversations about the United States presidential race, a recurring topic has been the cognitive capacity of candidates and some speculation about "cognitive decline"—but what does this mean in terms of a person's health?
July 29th, 2024 — Source

Social isolation change associated with increased risk of mortality, disability, and dementia
In a recent study published in JAMA Network Open, researchers evaluated the relationship between social isolation and health outcomes such as cognitive and physical function decline, cardiovascular disease (CVD), stroke, and mortality in older adult residents of the United States (US).
July 29th, 2024 — Source

Health — Alzheimers — July 26th, 2024

Anxiety's Long-Term Impact on Dementia Development
In a recent study published in the Journal of the American Geriatrics Society, a group of researchers assessed the longitudinal relationship between chronic, resolved, and new onset anxiety and the risk of all-cause dementia (Progressive cognitive decline affecting memory and thinking).
July 26th, 2024 — Source

European medicines watchdog rejects new Alzheimer's drug
Europe's medicines watchdog on Friday rejected a marketing request for a new Alzheimer's disease treatment, saying the risks of the medicine's side effects, including potential brain bleeding, outweighed the benefits.
July 26th, 2024 — Source

Nasal spray clears proteins linked to Alzheimer's, study finds
Scientists in America have developed a nasal spray that can remove proteins in the brain associated with Alzheimer's disease—at least, in mice.
July 26th, 2024 — Source

Researchers move a step closer to developing at-home test to detect dementia
Tasmanian scientists are a step closer to developing a computer test that can detect dementia, decades before any memory symptoms emerge, recent research has found.
July 26th, 2024 — Source

Health — Alzheimers — July 24th, 2024

Body composition can affect risk of dementia or Parkinson's, research suggests
People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology.
July 24th, 2024 — Source

Building a molecular brain map to understand Alzheimer's disease
Resulting atlas of the aging human brain holds molecular insights into the brain's vulnerability and resilience.
July 24th, 2024 — Source

Chronic and new anxiety tied to increased dementia risk
In a study published in the Journal of the American Geriatrics Society, both chronic and new anxiety were associated with an increased risk of dementia. However, where anxiety had resolved, there was no association with dementia risk.
July 24th, 2024 — Source

Comprehensive dataset from A4 study yields key insights about Alzheimer's disease
Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition. The comprehensive dataset has already yielded key insights about Alzheimer's disease, which affects nearly seven million people in the United States, and sharing the data opens avenues for further progress.
July 24th, 2024 — Source

New analysis offers most comprehensive roadmap to date for more targeted Alzheimer's research, drug discovery
From studying the human genome to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin dementia. But there's a catch: While new technologies are revealing myriad avenues for Alzheimer's research, it's impossible to know in advance which research pathways will lead to effective treatments.
July 24th, 2024 — Source

Six ways to look after your brain health in your 20s and 30s
Dementia is not an inevitable consequence of aging. It's thought that around 40% of dementia cases could be prevented (or at least delayed) by changing certain lifestyle habits.
July 24th, 2024 — Source

Study across multiple brain regions discerns Alzheimer's vulnerability and resilience factors
An MIT study published in Nature provides new evidence for how specific cells and circuits become vulnerable in Alzheimer's disease, and hones in on other factors that may help some people show resilience to cognitive decline, even amid clear signs of disease pathology.
July 24th, 2024 — Source or Source

Unique neutrophil type associated with Alzheimer's disease identified
Researchers have identified a unique type of neutrophil significantly associated with Alzheimer's disease (AD) pathology and mapped the transcriptome of neutrophils in the peripheral blood of AD mice.
July 24th, 2024 — Source

Health — Alzheimers — July 22nd, 2024

Empowering human intelligence: Strategies for healthy aging and memory
People can reduce their risk of age-related dementia by exercising their brains properly instead of Googling, according to a leading Canadian academic.
July 22nd, 2024 — Source

Study identifies new biomarkers of Alzheimer's disease
Recent advances in the study of proteomes (i.e., the entire range of proteins expressed by human cells and tissues) have opened new opportunities for identifying the biological markers of specific diseases or mental disorders. This could in turn inform the prevention, diagnosis and treatment of these medical conditions.
July 22nd, 2024 — Source

Health — Alzheimers — July 19th, 2024

Does hormone-modulating therapy for breast cancer treatment affect risk for Alzheimer disease and related dementias?
In a recent study published in JAMA Network Open, researchers investigated the association between hormone-modulating therapy (HMT) for breast cancer treatment and the risk of developing Alzheimer's disease and related dementias (ADRD) (a group of cognitive disorders causing memory loss and impaired thinking) in women aged 65 years or older.
July 19th, 2024 — Source

Health — Alzheimers — July 18th, 2024

A reliable artificial intelligence-guided marker for early dementia prediction
A recent eClinicalMedicine study utilized machine learning (ML) techniques to develop and test a predictive prognostic model (PPM) for early dementia prediction using real-world patient data.
July 18th, 2024 — Source

Health — Alzheimers — July 5th, 2024

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology
In a recent study published in IScience, a team of researchers from the United States examined the impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways in mitochondrial function, autophagy, and liposomes using mouse astrocytes and human cells.
July 5th, 2024 — Source

Health — Alzheimers — July 2nd, 2024

New protein target identified for early Alzheimer's treatment
A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State. They found that disrupting necessary sugar modifications of these proteins promotes cell repair and reverses cellular abnormalities that occur in neurodegenerative diseases.
July 2nd, 2024 — Source

Health — Alzheimers — June 28th, 2024

Biology-based criteria for diagnosis, staging of Alzheimer's disease
The Alzheimer's Association has published revised criteria for the diagnosis and staging of Alzheimer's disease that are based on the biology of the disease and reflect recent advancements in research, diagnostics and treatment.
June 28th, 2024 — Source

Protein maps created using scanning technology on cerebrospinal fluid to find markers for Alzheimer's
A large team of neuroscientists, biochemists and Alzheimer's specialists affiliated with institutions in the U.S. and Iceland has created a protein map to look for patterns in cerebrospinal fluid that may serve as markers for the onset of Alzheimer's disease decades before diagnosis.
June 28th, 2024 — Source

Serotonin 2C receptor regulates memory in mice and humans: Implications for Alzheimer's disease
Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and animal models. The findings, published in the journal Science Advances, not only provide new insights into the factors involved in healthy memory but also in conditions associated with memory loss, like Alzheimer's disease, and suggest novel avenues for treatment.
June 28th, 2024 — Source

Health — Alzheimers — June 26th, 2024

Differences in effectiveness among antihyperglycemic drugs on dementia risk identified in recent study
A recent study published in eClinical Medicine compares the effectiveness of anti-diabetes medications in reducing the risk of dementia in older diabetics.
June 26th, 2024 — Source

Eye disease links potential biomarker to Alzheimer's disease found in the retina
Researchers at the University of Alabama at Birmingham have found a potential link between putative retinal gliosis and Alzheimer's disease. The study, published in Investigative Ophthalmology & Visual Science, demonstrates that putative retinal gliosis could be a sign of Alzheimer's disease-related neuroinflammation, an inflammatory response within the brain or spinal cord.
June 26th, 2024 — Source

Researchers identify vascular changes in the brain linked to Alzheimer's disease
The blood-brain barrier—a network of blood vessels and tissues that nurtures and protects the brain from harmful substances circulating in the blood—is disrupted in Alzheimer's disease. Now, researchers at Mayo Clinic and collaborators have uncovered unique molecular signatures of blood-brain barrier dysfunction that could point to new ways to diagnose and treat the disease.
June 26th, 2024 — Source

Researchers uncover molecular signatures of blood-brain barrier dysfunction in Alzheimer's disease
The blood-brain barrier -; a network of blood vessels and tissues that nurtures and protects the brain from harmful substances circulating in the blood -; is disrupted in Alzheimer's disease. Now, researchers at Mayo Clinic and collaborators have uncovered unique molecular signatures of blood-brain barrier dysfunction that could point to new ways to diagnose and treat the disease.
June 26th, 2024 — Source

University of Minnesota retracts pioneering studies in stem cells, Alzheimer's disease
Years after questions were raised about their integrity, two of the University of Minnesota's highest-profile scientific discoveries have been retracted in one week—one that offered hope over the therapeutic potential of stem cells and the other that offered a promising path toward treating Alzheimer's disease.
June 26th, 2024 — Source

Health — Alzheimers — June 24th, 2024

Bank statements reveal clues to excessive spending and cognitive decline
Early memory loss has been linked to wealth loss, but research has mostly focused on investments. Four years ago, clinical geropsychologist Peter Lichtenberg, Ph.D., wondered what clues might be found in an older person's financial decisions to indicate their vulnerability to financial victimization.
June 24th, 2024 — Source

'Fit2Drive' transforms assessing older drivers with cognitive decline
As the world's population ages, so does the proportion of older drivers on the road. Safe driving requires adequate memory, perceptual and motor skills, and executive function abilities. Although individuals with severe Alzheimer's disease and related dementias (ADRD) are no longer able to drive safely, changes in driving performance may start at the preclinical stage of AD.
June 24th, 2024 — Source

Meet CARMEN, a robot that helps people with mild cognitive impairment
Meet CARMEN, short for Cognitively Assistive Robot for Motivation and Neurorehabilitation—a small, tabletop robot designed to help people with mild cognitive impairment (MCI) learn skills to improve memory, attention, and executive functioning at home.
June 24th, 2024 — Source or Source

Signaling pathway in brain helps maintain balance in microglia, prevent cognitive deficit
A new study led by University of Cincinnati researchers sheds new light on the role of a signaling pathway in the brain to maintain health and prevent inflammation and cognitive deficits.
June 24th, 2024 — Source

Health — Alzheimers — June 21st, 2024

Brain health is rooted in state of mind, finds study
Having more positive experiences in life is associated with lower odds of developing brain disorders like Alzheimer's disease, slower cognitive decline with age, and even a longer life.
June 21st, 2024 — Source

Clinical trial reports promising new treatment reduces suffering in Sanfilippo syndrome
As a neurodegenerative disease characterized by childhood onset dementia, Sanfilippo syndrome causes immense suffering in many ways, including pain, loss of speech, extreme agitation, and distress, gastrointestinal symptoms, and profound sleep disturbance. With no approved treatment, clinical specialists have had few options to help alleviate this suffering until now.
June 21st, 2024 — Source

Genetics of Alzheimer's disease: First identification of a strong recessive component
A new study from deCODE genetics and collaborators is the first to uncover a strong recessive component in Alzheimer's disease.
June 21st, 2024 — Source

New genetic clue in understanding increased Alzheimer's risk
Scientists have discovered a new piece of the puzzle in understanding why some people are more susceptible to Alzheimer's disease. The research has been published in the journal Nature Communications.
June 21st, 2024 — Source

Study finds causal evidence tying cerebral small-vessel disease to Alzheimer's and dementia
Research led in part by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) finds that the most common cerebral small-vessel disease feature seen in brain magnetic resonance imaging is a primary vascular factor associated with dementia risk.
June 21st, 2024 — Source

Health — Alzheimers — June 20th, 2024

Novel treatment effectively treats cognitive decline in mice with Alzheimer's disease
Alzheimer's disease is a progressive, neurodegenerative disorder that is the leading cause of dementia, and it involves cognitive decline, memory loss, and ultimately the inability to perform daily tasks.
June 20th, 2024 — Source

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease
A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals -; Mass Eye and Ear and Massachusetts General Hospital (MGH)-; reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.
June 20th, 2024 — Source

Removal of ovaries before menopause associated with reduced white matter in brain
Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life. White matter refers to the nerve fibers that connect neurons in different areas of the brain.
June 20th, 2024 — Source

Self-administered test in primary care offices found to increase early diagnosis of cognitive disorders
Primary care providers often are the first to identify and evaluate patients with neurocognitive disorders such as mild cognitive impairment, Alzheimer's and dementia.
June 20th, 2024 — Source

Health — Alzheimers — June 17th, 2024

A new drug could slow Alzheimer's: But can patients get it?
It's welcome news for Alzheimer's patients and their families: A Food and Drug Administration advisory panel unanimously recommended approval for Eli Lilly & Co.'s treatment donanemab. If given the agency's green light later this year, it would be the second drug to target amyloid plaques in the brain, which have been associated with the memory-destroying disease.
June 17th, 2024 — Source

Study suggests maternal inheritance of Alzheimer's disease tied to increased risk of developing disease
A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences the risk of biological changes in the brain that lead to the disease. By evaluating 4,400 cognitively unimpaired adults ages 65--85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains.
June 17th, 2024 — Source

Health — Alzheimers — June 14th, 2024

Is it really possible to have Alzheimer's disease, yet no symptoms?
Some people seem to be more resilient to developing Alzheimer's disease, despite having the biological hallmarks of the devastating disease. For obvious reasons, scientists are very interested in studying this special group of people.
June 14th, 2024 — Source

New metric for blood circulation in brain to better understand dementia
Each time the heart beats, it pumps blood through the brain vessels, causing them to expand slightly and then relax, much like the rise and fall of the blood pulsing through your veins when you feel your pulse in your wrist. This pulsation in the brain helps distribute blood evenly across different areas of the brain, ensuring that all parts receive the oxygen and nutrients they need to function properly.
June 14th, 2024 — Source

Study reveals FUS protein's role in two neurodegenerative diseases
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might play a role, but the exact mechanism remained a mystery.
June 14th, 2024 — Source

Survey shows 4.0 percent of seniors received dementia diagnosis in 2022
In 2022, 4.0 percent of adults aged 65 years and older reported ever having received a dementia diagnosis, with similar percentages seen for men and women, according to a study published online June 13 in the National Health Statistics Reports, a publication from the National Center for Health Statistics (PDF).
June 14th, 2024 — Source

Health — Alzheimers — June 12th, 2024

Does having a child with low birth weight increase a person's risk of dementia?
People who give birth to infants less than 5.5 pounds may be more likely to have memory and thinking problems later in life than people who give birth to infants who do not have a low birth weight, according to a study published in the June 12, 2024, online issue of Neurology. The effect on memory and thinking skills was equivalent to one to two years of aging for those with low-birth-weight deliveries.
June 12th, 2024 — Source

How perceived age impacts dementia caregivers and their loved ones
The felt age of spousal caregivers is connected to the felt age of their loved ones living with dementia, according to a study from the University of Surrey. This perceived age in people with dementia and their caregivers is related to their own well-being, satisfaction with life, and self-confidence.
June 12th, 2024 — Source

When mice with Alzheimer's inhaled menthol, their cognitive abilities improved
Imagine a future where the smell of menthol could alleviate some of the worst symptoms of Alzheimer's disease. This might sound like science fiction, but innovative new research is making it a potential reality.
June 12th, 2024 — Source

Health — Alzheimers — June 10th, 2024

New brain connectivity model predicts dementia years before diagnosis
In a recent study published in Nature Mental Health, a group of researchers evaluated if a neurobiological model of the default-mode network (DMN) effective connectivity can predict future dementia diagnosis at the individual level.
June 10th, 2024 — Source or Source

Tips to making your home safer for people with Alzheimer's
Bright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.
June 10th, 2024 — Source

Vigorous exercise linked to lower dementia risk in hypertensive individuals
In a recent study published in Alzheimer's and Dementia, a group of researchers investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension.
June 10th, 2024 — Source

Health — Alzheimers — June 8th, 2024

Can Alzheimer's really be reversed, as a new documentary claims?
Two people diagnosed with Alzheimer's claim to have conquered the disease through simple lifestyle changes.
June 8th, 2024 — Source

Health — Alzheimers — June 7th, 2024

New study reveals Viagra improves brain blood flow and could help prevent dementia
A new trial conducted by the University of Oxford reveals that sildenafil, commonly known as Viagra, enhances blood flow to the brain and improves the function of brain blood vessels in patients at a heightened risk of vascular dementia.
June 7th, 2024 — Source

New therapeutic approach for frontotemporal dementia uses modified viruses to replace a missing protein in the brain
Frontotemporal dementia is a currently incurable brain disease causing memory loss, speech disorders, and changes in personality. In 5–12% of cases, a decline in progranulin triggers the disease. The loss of this protein leads to deficiencies in protein breakdown, resulting in the deposition of insoluble toxic proteins. This leads to inflammation of the brain, neuronal death, and associated massive functional disorders of the central nervous system.
June 7th, 2024 — Source

Health — Alzheimers — June 6th, 2024

First-of-its-kind test can predict dementia up to nine years before diagnosis
Researchers at Queen Mary, University of London have developed a new method for predicting dementia with over 80% accuracy and up to nine years before a diagnosis. The new method provides a more accurate way to predict dementia than memory tests or measurements of brain shrinkage, two commonly used methods for diagnosing dementia.
June 6th, 2024 — Source or Source

Long-read RNA sequencing reveals key gene expressions in Alzheimer's disease
Researchers at the University of Kentucky Sanders-Brown Center on Aging are working to develop a pre-symptomatic disease diagnostic tool for Alzheimer's disease.
June 6th, 2024 — Source

Ohio State creates user-friendly repository to help study Alzheimer's disease
Neuroscience and biomedical informatics researchers at The Ohio State University Wexner Medical Center and College of Medicine created the comprehensive, user-friendly repository.
June 6th, 2024 — Source

Research team develops searchable database for Alzheimer's research
Neuroscience and biomedical informatics researchers at The Ohio State University Wexner Medical Center and College of Medicine created the comprehensive, user-friendly repository.
June 6th, 2024 — Source

Health — Alzheimers — May 30th, 2024

Memory decline reported by patients and partners may signal early Alzheimer's changes
A new study adds further evidence that when a patient or family member notices signs of persistent memory loss, it's important to speak with a doctor. While there are many reasons why someone's memory may change, researchers from Mass General Brigham who are studying patients prior to diagnosis with Alzheimer's disease found changes in the brain when patients and their study partners-;those who could answer questions about their daily cognitive function-;reported a decline in cognition.
May 30th, 2024 — Source

Health — Alzheimers — May 29th, 2024

Dementia fighter: Orienteering helps brain and body alike, with greater benefits for those who move quickest
The sport of orienteering, which simultaneously combines exercise with challenging navigation, may be better for the brain than exercise alone, according to new research from kinesiologists at McMaster University.
May 29th, 2024 — Source

Health — Alzheimers — May 28th, 2024

New Help for Dealing With Aggression in People With Dementia
Caring for older adults with dementia is stressful, especially when they become physically or verbally aggressive, wander away from home, develop paranoia or hallucinations, engage in inappropriate or repetitive behaviors, or refuse to let caregivers help them.
May 28th, 2024 — Source or Source

Health — Alzheimers — May 23rd, 2024

Tips for traveling with a loved one with Alzheimer's
Experts are expecting this Memorial Day weekend to be the busiest yet, with nearly 44 million Americans projected to travel between Thursday and Monday.
May 23rd, 2024 — Source

Tracking the cellular and genetic roots of neuropsychiatric disease
A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.
May 23rd, 2024 — Source

Health — Alzheimers — May 21st, 2024

Can a coach-supported mobile health intervention reduce dementia risk?
In a recent study published in The Lancet Healthy Longevity, researchers conducted an open-label, hybrid effectiveness-implementation, blinded endpoint randomized controlled trial (RCT) to evaluate whether a coach-supported mobile health (mHealth) intervention can reduce dementia risk factors in high-risk, underserved populations.
May 21st, 2024 — Source

National University Hospital testing predictive AI for Alzheimer's diagnosis and more AI briefs
Also, IHH Healthcare is now offering AI-based sleep monitoring solutions.
May 21st, 2024 — Source

People with dementia aren't currently eligible for voluntary assisted dying. Should they be?
Dementia is the second leading cause of death for Australians aged over 65. More than 421,000 Australians currently live with dementia and this figure is expected to almost double in the next 30 years.
May 21st, 2024 — Source

Scientists aim to stop harmful gut bacteria triggering Alzheimer's
The phrase 'you are what you eat' was coined almost a century before Alois Alzheimer made his breakthrough in identifying brain disease, but the evidence is now clear that diet as well as age influences the brain.
May 21st, 2024 — Source

Social mobility extends years lived without dementia, Japanese study reveals
Upward social mobility may ward off dementia, according to a new study. Dementia, a collective term for conditions marked by memory loss and diminished cognitive functioning, strains health care systems and devastates quality of life for patients and their families.
May 21st, 2024 — Source

Health — Alzheimers — May 17th, 2024

Black adults at risk for Alzheimer's disease live in more polluted areas, study finds
A study by Duke and Columbia Universities finds older, non-white adults are more likely to live in areas with higher air pollution and near toxic disposal sites, among or environmental injustices, potentially underlying their cognitive health.
May 17th, 2024 — Source

Researcher discovers drug that may delay onset of Alzheimer's, Parkinson's disease and treat hydrocephalus
A researcher in the Keck School of Medicine of USC's department of surgery has discovered a potential breakthrough in delaying the onset of Alzheimer's and Parkinson's disease and treating hydrocephalus. Young-Kwon Hong, Ph.D., the chief of basic science research in the department of surgery, and his team have developed a drug that can help clear fluid and cellular debris from the brain.
May 17th, 2024 — Source

Study suggests that air pollution promotes inflammation in the brain, accelerating consequences for dementia
Results from a new study suggest that long-term exposure to air pollution leads to increased risk in dementia in Denmark.
May 17th, 2024 — Source

Health — Alzheimers — May 14th, 2024

Innovative 'mini-brains' could revolutionize Alzheimer's treatment
New research could revolutionize the way Alzheimer's and other brain-related diseases are diagnosed and treated -- by building tiny brains in a petri dish.
May 14th, 2024 — Source

'MUSIC map' reveals some brain cells age faster and are more prevalent in Alzheimer's
Engineers at the University of California San Diego have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer's disease. Additionally, researchers observed sex-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of "old" oligodendrocytes to "old" neurons compared to the male cortex.
May 14th, 2024 — Source

New research presents 'mini-brains' that could advance Alzheimer's treatment
Using an innovative new method, a University of Saskatchewan (USask) researcher is building tiny pseudo-organs from stem cells to help diagnose and treat Alzheimer's.
May 14th, 2024 — Source

Over 20,000 people join UK search for new dementia treatments
More than 20,000 volunteers have been recruited to a resource aimed at speeding up the development of much-needed dementia drugs. The cohort will enable scientists in universities and industry to involve healthy individuals who may be at increased risk of dementia in clinical trials to test whether new drugs can slow the decline in various brain functions including memory and delay the onset of dementia.
May 14th, 2024 — Source

Research links sleep apnea severity during REM stage to verbal memory decline
A research team led by the University of California, Irvine has revealed the link between the frequency of sleep apnea events during the rapid-eye-movement stage and the severity of verbal memory impairment in older adults at risk for Alzheimer's disease. Verbal memory refers to the cognitive ability to retain and recall information presented through spoken words or written text and is particularly vulnerable to Alzheimer's.
May 14th, 2024 — Source

Study explores role of epigenetics, environment in differing Alzheimer's risk between Black and white communities
A study from North Carolina State University has found that environmentally caused alterations to specific areas of the genome—known as imprint control regions—during early development may contribute to the risk of developing Alzheimer's disease, and that Black people may be more affected than white people. The work adds to our understanding of the ways in which environmental factors can contribute to genetic alterations and disease susceptibility.
May 14th, 2024 — Source

Study reveals racial disparities in diagnosis and drug use for dementia symptoms
Compared to Black and Asian people, white and Hispanic people with Alzheimer's disease and related dementias were most likely to be diagnosed with symptoms like depression and agitation, according to a new study from the USC Schaeffer Center for Health Policy & Economics.
May 14th, 2024 — Source

Study sheds light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's disease
A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease.
May 14th, 2024 — Source

Health — Alzheimers — May 12th, 2024

Study suggests two copies of APOE4 gene behind up to 20% of Alzheimer's cases
A team of neurologists affiliated with multiple institutions in Spain and the U.S. has found evidence that suggests up to 20% of all cases of Alzheimer's disease (AD) may be attributable to double copies of the APOE4 gene.
May 12th, 2024 — Source

Health — Alzheimers — May 10th, 2024

Flicker stimulation shines in clinical trial for epilepsy
Biomedical engineer Annabelle Singer has spent the past decade developing a noninvasive therapy for Alzheimer's disease that uses flickering lights and rhythmic tones to modulate brain waves. Now she has discovered that the technique, known as flicker, also could benefit patients with a host of other neurological disorders, from epilepsy to multiple sclerosis.
May 8th, 2024 — Source

Health — Alzheimers — May 8th, 2024

'Mathematical microscope' reveals novel, energy-efficient mechanism of working memory that works even during sleep
Researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and where Alzheimer's disease begins.
May 8th, 2024 — Source

New tool links Alzheimer's disease types to rate of cognitive decline
Mayo Clinic researchers have discovered a series of brain changes characterized by unique clinical features and immune cell behaviors using a new corticolimbic index tool for Alzheimer's disease, a leading cause of dementia.
May 8th, 2024 — Source

Study suggests daily consumption of olive oil reduces chances of developing dementia
A team of nutritionists and medical researchers at the Harvard T.H. Chan School of Public Health has found evidence that daily consumption of olive oil may reduce the chances of developing dementia.
May 8th, 2024 — Source

Health — Alzheimers — May 7th, 2024

Terminal lucidity: Why do loved ones with dementia sometimes 'come back' before death?
Dementia is often described as "the long goodbye." Although the person is still alive, dementia slowly and irreversibly chips away at their memories and the qualities that make someone "them."
May 7th, 2024 — Source

Health — Alzheimers — May 3rd, 2024

Worried about dementia? Here's why I'm ditching GPS for a road atlas
The thinning of the hippocampi, a part of the brain responsible for spatial navigation, has been conclusively linked to the onset of dementia due to its under-utilization thanks to an over-dependence on GPS-enabled maps.
May 3rd, 2024 — Source

Health — Alzheimers — April 30th, 2024

Does obesity really increase your risk of dementia?
Many dementia charities advise people to maintain a healthy weight to reduce their risk of dementia. But some studies have suggested that obesity might actually protect against dementia. What does the science say?
April 30th, 2024 — Source

Neuroscientists find integrity of white brain matter in superagers does not deteriorate, explains sharp memory
A team of neuroscientists from Universidad Politecnica de Madrid and Queen Sofia Foundation Alzheimer Center, both in Spain, has found that so-called superagers maintain memory as they grow older because they do not experience a decline in the integrity of their white brain matter.
April 30th, 2024 — Source

Seattle startup Rippl acquires Kinto to boost dementia care services
Rippl, a Seattle startup that supports dementia care, acquired Kinto, a Boston startup that provides coaching services to family caregivers.
April 30th, 2024 — Source

Health — Alzheimers — April 26th, 2024

Clients got HIV through 'Vampire facial' microneedling treatments
Between 2018 and the spring of 2023, a cluster of clients who had gotten 'vampire facial' microneedling skin treatments at a New Mexico spa were diagnosed with HIV, probably via poorly cleaned instruments, a new report finds.
April 26th, 2024 — Source

What is childhood dementia? And how could new research help?
"Childhood" and "dementia" are two words we wish we didn't have to use together. But sadly, around 1,400 Australian children and young people live with currently untreatable childhood dementia.
April 26th, 2024 — Source

Health — Alzheimers — April 24th, 2024

Longest study to date assesses cognitive impairment over time in adults with essential tremor
Essential tremor, a nervous system disorder that causes rhythmic shaking, is one of the most common movement disorders. A new study published in the Annals of Neurology reveals details on the increased risk of mild cognitive impairment (MCI) and dementia that individuals with essential tremor may face.
April 24th, 2024 — Source

Health — Alzheimers — April 22nd, 2024

Grindr sued for allegedly sharing users' HIV status and other info with ad companies
The service is accused of divulging sensitive information without consent.
April 22th, 2024 — Source or Source

Mitochondrial depletion in axons linked to protein accumulation in neurodegenerative diseases
Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's. They used fruit flies to show that depletion of mitochondria in axons can directly lead to protein accumulation.
April 22th, 2024 — Source

Study shows how depletion of mitochondria in axons can directly lead to protein accumulation
Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's.
April 22th, 2024 — Source

Using AI to improve Alzheimer's treatment through the 'gut-brain axis'
Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.
April 22th, 2024 — Source

Health — Alzheimers — April 19th, 2024

A new therapeutic target for traumatic brain injury
For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, but they come with an amplified risk of developing dementia in the future.
April 19th, 2024 — Source

Health — Alzheimers — April 17th, 2024

How Alzheimer's disease progresses faster in people with Down syndrome
Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age. A new study by researchers at Washington University School of Medicine in St. Louis shows that the disease both starts earlier and moves faster in people with Down syndrome, a finding that may have important implications for the treatment and care of this vulnerable group of patients.
April 17th, 2024 — Source

Health — Alzheimers — April 15th, 2024

Local greenery and low crime rates may reduce dementia risk factors
Living in areas with shorter distances to greenspace and lower crime rates are associated with having fewer modifiable dementia risk factors, Monash University-led research has found.
April 15th, 2024 — Source

Health — Alzheimers — April 12th, 2024

Brain Boosters: 12 Memory-Enhancing Foods for Your Cognitive Health
These foods will help you maintain a healthy brain and may even prevent conditions like dementia.
April 12th, 2024 — Source

Health — Alzheimers — April 10th, 2024

Young-onset Alzheimer's: When symptoms begin before age 65
When Alzheimer's begins in middle age, misdiagnosis may be more likely. This rare form of Alzheimer's affects work, finances and family.
April 10th, 2024 — Source

Health — Alzheimers — April 5th, 2024

Human neuron model paves the way for new Alzheimer's therapies
Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia. This new model has led to the identification of novel therapeutic targets that could potentially block tau spread.
April 5th, 2024 — Source or Source

Health — Alzheimers — April 2nd, 2024

Hospice care for those with dementia falls far short of meeting people's needs at the end of life, says physician
Jimmy Carter, who chose to forgo aggressive medical care for complications of cancer and frailty in February 2023, recently reached his one-year anniversary since enrolling in hospice care. During this time, he celebrated his 99th birthday, received tributes far and wide and stood by the side of his beloved wife, Rosalynn, who died in November 2023.
April 2nd, 2024 — Source

Ultrasound alone improves cognitive function in neurodegenerative disorders, UQ study finds
University of Queensland researchers have found targeting amyloid plaque in the brain is not essential for ultrasound to deliver cognitive improvement in neurodegenerative disorders.
April 2nd, 2024 — Source or Source

Health — Alzheimers — March 29th, 2024

High-resolution images reveal similarities in protein structures between Alzheimer's disease and Down syndrome
More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55--60.
March 29th, 2024 — Source

Health — Alzheimers — March 28th, 2024

Familial Alzheimer's disease transferred via bone marrow transplant in mice
Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show in the journal Stem Cell Reports. When the team transplanted bone marrow stem cells from mice carrying a hereditary version of Alzheimer's disease into normal lab mice, the recipients developed Alzheimer's disease—and at an accelerated rate.
March 28th, 2024 — Source

Generation of tau dephosphorylation-targeting chimeras for the treatment of tauopathies
Accumulation of pathologic tau protein plays a pivotal role in the neurodegeneration of Alzheimer's disease (AD) and many other tauopathies. Thus, amelioration of pathological tau aggregates in the brain is an important direction for the development of drugs.
March 28th, 2024 — Source

Patients with delirium more likely to develop dementia, finds study
University of Queensland researchers have found older patients who experience delirium are three times more likely to develop dementia. Professor Ruth Hubbard from UQ's Center for Health Services Research (CHSR) said the study also found that every episode of delirium increased the chance of developing dementia by 20%.
March 28th, 2024 — Source

Research links age-related inflammation, microglia and Alzheimer's disease
Stanford researchers have uncovered a potential role for a protein called TREM1 in the development of age-related inflammation, cognitive decline, and Alzheimer's disease. This discovery could pave the way for new therapeutic strategies to combat these conditions.
March 28th, 2024 — Source

Unlocking how to use mRNA to target Alzheimer's disease
Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.
March 28th, 2024 — Source

Health — Alzheimers — March 27th, 2024

Evolving brain sizes from 1930 to 1970 could signal decreased dementia risk, researchers say NewsGuard 100/100 Score
The development and upkeep of the human brain are influenced by both genetic factors and environmental conditions, which may subsequently impact the risk of dementia later in life. Thus, a recent study published in JAMA Neurology assessed whether there were changes in skull and brain size, as well as the thickness of the cortex, across individuals born between the years 1930 and 1970.
March 27th, 2024 — Source

Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham heart study
Dementia refers to a set of symptoms marked by a decline in cognitive abilities, including memory, language, reasoning and everyday tasks. It can result from various causes, such as Alzheimer's disease, vascular problems, traumatic brain injuries and other health issues.
March 27th, 2024 — Source

Xenotransplantation model used for studying microglial response to Alzheimer's disease
Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's. The exact mechanism behind this contribution is not yet fully understood due to the complexities involved in studying them in human brain samples.
March 27th, 2024 — Source

Health — Alzheimers — March 25th, 2024

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer
Researchers at the USC Leonard Davis School of Gerontology have discovered a genetic mutation in a small mitochondrial protein that may promote longevity, preserve cognitive function, and protect against Alzheimer's disease among carriers of APOE4, a gene associated with a dramatic increase in the risk of developing Alzheimer's disease.
March 25th, 2024 — Source

Study adds new evidence on the link between Type 2 diabetes and Alzheimer's disease
New research conducted in mice offers insights into what's going on at the molecular level that could cause people with diabetes to develop Alzheimer's disease.
March 25th, 2024 — Source

Health — Alzheimers — March 22nd, 2024

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease
Review of drugs targeting CaMKII will help better investigate its function
March 22nd, 2024 — Source

Health — Alzheimers — March 20th, 2024

Investigating racial and ethnic differences in Medicare costs for older adults with dementia
In an analysis of information on Medicare beneficiaries with dementia, Medicare expenditures were higher for Black and Hispanic individuals compared with whites. The Journal of the American Geriatrics Society analysis also found that expenditures were highest for Black beneficiaries in every phase of care.
March 20th, 2024 — Source

Nutrition and Alzheimer's disease may be linked, study finds
Malnutrition may increase a person's chances of contracting Alzheimer's disease, which in turn exacerbates malnutrition. That's according to a March 2024 study out of China published in Frontiers in Nutrition.
March 20th, 2024 — Source

Rural and minority dementia patients face disparities in access to neurologists, study finds
Getting dementia diagnosed can be a long and difficult process for anyone, but some may face additional challenges based on race or ethnicity and where they live, according to a study led by Washington State University researchers.
March 20th, 2024 — Source

Study shows barriers to dementia diagnosis based on race, ethnicity, and location
Getting dementia diagnosed can be a long and difficult process for anyone, but some may face additional challenges based on race or ethnicity and where they live, according to a study led by Washington State University researchers.
March 20th, 2024 — Source

The middle-aged brain changes a lot—and it's key to understanding dementia
Our brains change more rapidly at various times of our lives, as though life's clock was ticking faster than usual. Childhood, adolescence and very old age are good examples of this. Yet for much of adulthood, the same clock seems to tick fairly regularly. One lap around the sun; one year older.
March 20th, 2024 — Source

X-Ray activated nanoparticles halt Alzheimer's in study
A novel approach in the field of Alzheimer's research is emerging that could potentially transform how we tackle this debilitating disease. Recent studies have revealed a paradigm shift in understanding Alzheimer's pathology, emphasizing the importance of targeting the early-stage aggregation of the pathogenic amyloid beta (A-beta) protein, specifically focusing on its soluble oligomeric form.
March 20th, 2024 — Source

Health — Alzheimers — March 18th, 2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases that commonly occur in middle-aged people. FTD is second only to Alzheimer's disease in terms of dementia prevalence. Both ALS and FTD arise from neuronal degeneration through mechanisms that remain unclear.
March 18th, 2024 — Source

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease
A new Viewpoint article published in the Journal of the American Medical Association (JAMA), titled " Use of Lecanemab for Patients with Cardiovascular Disease—The Challenge of Uncertainty," advocates for additional research to improve decision making prior to initiating lecanemab, commercially known as Leqembi, an FDA-approved Alzheimer's Disease drug.
March 18th, 2024 — Source

New fluid biomarker may one day detect ALS and FTD before symptoms appear
Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning -; the former affecting nerves in the brain and spinal cord leading to loss of movement, the latter eroding the brain regions controlling personality, behavior and language.
March 18th, 2024 — Source

Health — Alzheimers — March 15th, 2024

Researchers identify mutation that alters Alzheimer's disease progression
The scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of research and brings together 100 multidisciplinary specialists, identifying a mutation that alters Alzheimer's disease progression.
March 14th, 2024 — Source

Zebrafish discovery could speed testing of motor neuron diseas
Tiny, transparent fish have made it possible for Macquarie University neuroscientists to observe damaging protein clusters forming in real time, opening the way for testing potential early interventions for motor neuron disease (MND) and dementia.
March 14th, 2024 — Source

Health — Alzheimers — March 14th, 2024

A healthier diet is linked with a slower pace of aging, reduced dementia risk, study shows
A healthier diet is associated with a reduced dementia risk and slower pace of aging, according to a new study. The findings show that a diet-dementia association was at least partially facilitated by multi-system processes of aging. Until now, the biological
March 14th, 2024 — Source

Alzheimer's drug fermented with help from AI and bacteria moves closer to reality
Galantamine is a common medication used by people with Alzheimer's disease and other forms of dementia around the world to treat their symptoms. Unfortunately, synthesizing the active compounds in a lab at the scale needed isn't commercially viable. The active ingredient is extracted from daffodils through a time-consuming process, and unpredictable factors, such as weather and crop yields, can affect supply and price of the drug.
March 14th, 2024 — Source or Source

Concussion from explosive blasts may induce Alzheimer's biomarkers in middle-aged veterans
Middle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid similar to people who develop Alzheimer's disease, according to a new study published in the March 13, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
March 14th, 2024 — Source

One step back: Why the new Alzheimer's plaque-attack drugs don't work
On Jan. 31, aducanumab, a pricey drug approved for treatment of early-stage Alzheimer's disease, was withdrawn from the market. And in early March, the Food and Drug Administration delayed its decision regarding whether to approve a separate, closely similar drug. A prescient commentary by Stanford Medicine neurologist Mike Greicius, MD, in the Journal of Alzheimer's Disease goes a long way toward explaining why.
March 14th, 2024 — Source

Poor neighborhoods linked to elevated dementia risk and faster brain aging
Living in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education, a Duke University-led study finds.
March 14th, 2024 — Source

Study highlights potential of p-tau217 assays in Alzheimer's clinical trials and diagnosis
In a recent study published in eBioMedicine, researchers compared the performance of two commercial phospho-tau217 (p-tau217) assays.
March 14th, 2024 — Source

Study shows a healthy diet is linked with a slower pace of aging, reduced dementia risk
A healthier diet is associated with a reduced dementia risk and a slower pace of aging, according to a new study at Columbia University Mailman School of Public Health and The Robert Butler Columbia Aging Center. The findings show that multi-system processes of aging at least partially facilitated a diet-dementia association.
March 14th, 2024 — Source

Health — Alzheimers — March 11th, 2024

Wrist device that monitors activity could help provide early warning of Alzheimer's
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer's disease, according to a recent study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
March 11th, 2024 — Source

Wristwatch-like devices detect early signs of Alzheimer's
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer's disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
March 11th, 2024 — Source

Health — Alzheimers — March 8th, 2024

FDA delays decision on new Alzheimer's drug
Instead of approving the new Alzheimer's drug donanemab this month, as was expected, the U.S. Food and Drug Administration will now require the experimental medication be scrutinized more closely by an expert panel, the drug's maker said Friday.
March 8th, 2024 — Source

Highly awaited Alzheimer's drug hit by delays
Eli Lilly's highly anticipated Alzheimer's drug has been held back for further review by regulators, the US pharmaceutical giant said Friday, in a blow for patients with the devastating brain disorder.
March 8th, 2024 — Source

Health — Alzheimers — March 6th, 2024

People with essential tremor may have increased risk of dementia
Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024.
March 6th, 2024 — Source

Social determinants of health increase Alzheimer's risk
Social determinants of health are increasing the risk of Alzheimer's disease and related dementia, finds a recent study from the Brown School and the School of Medicine at Washington University in St. Louis.
March 6th, 2024 — Source

Study could lead to new way to detect brain changes associated with Alzheimer's risk
New research suggests there is a link between abnormal blood levels of amyloid—a protein associated with Alzheimer's disease—and subtle changes in brain microstructures on a type of MRI, findings that could lead to a new way to detect Alzheimer's earlier in people with no clinical signs.
March 6th, 2024 — Source

Health — Alzheimers — March 1st, 2024

Better sleep is a protective factor against dementia
Dementia is a progressive loss of cognitive abilities, such as memory, that is significant enough to have an impact on a person's daily activities.
March 1st, 2024 — Source

Is posttraumatic epilepsy associated with long-term dementia risk?
Long-term dementia risk is associated with both head injury and epilepsy. However, research has thus far documented the links between post-traumatic epilepsy (PTE) and short-term cognitive outcomes.
March 1st, 2024 — Source

Study finds daily fiber supplement improves older adults' brain function in just 12 weeks
A daily fiber supplement improved brain function in people over 60 in just 12 weeks. The study, published recently in Nature Communications by researchers from the School of Life Course & Population Sciences showed that this simple and cheap addition to diet can improve performance in memory tests associated with early signs of Alzheimer's disease.
March 1st, 2024 — Source

Tiny magnetic particles in air pollution linked to development of Alzheimer's
Magnetite, a tiny particle found in air pollution, can induce signs and symptoms of Alzheimer's disease, new research suggests.
March 1st, 2024 — Source

Health — Alzheimers — February 28th, 2024

AI finds key signs that predict patient survival across dementia types
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients.
February 28th, 2024 — Source

ChatGPT aids in discovering potential Alzheimer's treatments through drug repurposing
In a recent proof-of-concept study published in the journal npj Digital Medicine, researchers from the United States of America used generative artificial intelligence (GAI) in the form of ChatGPT-4 (short for Chat generative pre-trained transformer 4) to identify drug repurposing candidates against Alzheimer's disease (AD).
February 28th, 2024 — Source

How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice
Studies at MIT and elsewhere are producing mounting evidence that light flickering and sound clicking at the gamma brain rhythm frequency of 40 Hz can reduce Alzheimer's disease (AD) progression and treat symptoms in human volunteers as well as lab mice.
February 28th, 2024 — Source

Promising pathways to simplified Alzheimer's diagnosis unveiled in new study
The Global Alzheimer's Platform Foundation (GAP) is releasing the first results from the Bio-Hermes-001 Study. This study of more than 1,000 community-based participants from throughout the U.S. compared the results of blood and digital biomarkers with brain amyloid PET scans or cerebrospinal fluid assays.
February 28th, 2024 — Source

Using machine learning to identify key predictors of mortality in dementia patients
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients.
February 28th, 2024 — Source

Health — Alzheimers — February 27th, 2024

Abdominal fat depots can impact brain health and cognition in individuals at high risk for Alzheimer's disease
The impact of abdominal fat on brain health and cognition is generally more pronounced in middle-aged men at high risk of Alzheimer's disease than in women, according to researchers at Rutgers Health.
February 27th, 2024 — Source or Source

How frontotemporal dementia changes the brain: Research is untangling its genetic causes
About 55 million people worldwide suffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was revealed that former talk show host Wendy Williams had been diagnosed with frontotemporal dementia, or FTD, a rare type of dementia that typically affects people ages 45 to 64.
February 27th, 2024 — Source

Health — Alzheimers — February 26th, 2024

A clearer image of glaucoma: The relationship between unfolding and aggregation for glaucoma-associated myocilin
From Parkinson's and Alzheimer's to cardiac arrhythmia, amyloids are linked to a number of diseases. These aggregates of proteins form in the body when a protein loses its normal structure and misfolds or mutates. And since many of these proteins are large and complicated, just how some of these mutations occur and aggregate remains a mystery—as does the creation of effective treatments.
February 26th, 2024 — Source

May I have a quick word? Study shows talking faster is linked to better brain health as we age
As we get older, we may start to notice it takes us longer to find the right words. This can lead to concerns about cognitive decline and dementia.
February 26th, 2024 — Source

Unlocking Alzheimer's secrets by studying neuropsychiatric symptoms
As the years add up, it's common to notice slight changes in our ability to remember and think. Older people who have more marked changes than their peers can be diagnosed with mild cognitive impairment (MCI). Currently, we can't easily predict which of these patients will develop Alzheimer's disease and which will not.
February 26th, 2024 — Source

What is frontotemporal dementia?
Frontotemporal dementia (FTD) is a group of neurologic disorders associated with changes in personality, behavior, language or movement. Some FTD forms are inherited, and some are not. Typically, people develop FTD symptoms before age 60.
February 26th, 2024 — Source

Yoga provides unique cognitive benefits to older women at risk of Alzheimer's disease, study finds
A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer's disease, including restoring neural pathways, preventing brain matter decline, and reversing aging and inflammation-associated biomarkers—improvements not seen in a group who received standard memory training exercises.
February 26th, 2024 — Source

Health — Alzheimers — February 23rd, 2024

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease
In experiments with lab-grown brain cells and mouse models, scientists at Johns Hopkins Medicine say they have discovered that a cell surface protein called Lag3 is not only a biological target for FDA-approved drugs that stimulate the immune system to attack cancer, but also may be a target for a drug designed to clean up "misfolded" Tau proteins linked to Alzheimer's disease.
February 23rd, 2024 — Source

Mouse study shows long COVID-19 infection linked with tangled protein that causes Alzheimer's disease
With a newly developed mouse model that more accurately represents human infection with COVID-19, Johns Hopkins scientists say they have found long-term infection with SARS-CoV-2 results in brain deposits of clumped and tangled Tau proteins commonly found in people with Alzheimer's disease.
February 23rd, 2024 — Source

Health — Alzheimers — February 21st, 2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings
A recent study reported that sildenafil, sold under the brand name Viagra, and other medicines from the same group called phosphodiesterase type-5 inhibitors may reduce the risk of Alzheimer's disease. But other research has found no effect.
February 21st, 2024 — Source

Heavy alcohol, drug use linked to increased risk of falls among people with HIV
The consequences of a fall can be devastating, particularly among people who are at higher risk of a fracture such as people with HIV. Alcohol consumption and drug use are important risk factors for falls or fractures, but there are no standard medical guidelines on the level of consumption or type of alcohol or other drug use (AOD) that increases one's risk for falls and fall-related injuries, particularly among populations with conditions that already affect balance.
February 21st, 2024 — Source

How AI can help spot early risk factors for Alzheimer's disease
UC San Francisco scientists have found a way to predict Alzheimer's disease up to seven years before symptoms appear by analyzing patient records with machine learning.
February 21st, 2024 — Source

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact
University of North Carolina at Chapel Hill researchers have developed a new drug delivery platform that harnesses helical amyloid fibers designed to untwist and release drugs in response to body temperatures.
February 21st, 2024 — Source

Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
About a decade ago, researchers in UC Santa Barbara chemistry professor Guillermo Bazan's lab began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes. Not good if the objective of the project was to harness the metabolism of living bacteria to produce electricity.
February 21st, 2024 — Source

Health — Alzheimers — February 19th, 2024

Drug repairs systems that remove Alzheimer's-causing waste from the brain, study shows
A team of Rutgers undergraduates has shown that an experimental drug known as Yoda1 may help drain cranial waste plus neurotoxins that cause Alzheimer's disease and other forms of dementia.
February 19th, 2024 — Source

Inside the plan to diagnose Alzheimer's in people with no memory problems and who stands to benefit
In a darkened Amsterdam conference hall this summer, a panel of industry and academic scientists took the stage to announce a plan to radically expand the definition of Alzheimer's disease to include millions of people with no memory complaints.
February 19th, 2024 — Source

Team develops highly accurate universal diagnostic blood test for Alzheimer's disease and mild cognitive impairment
An HKUST-led international research collaboration has achieved a significant milestone in Alzheimer's disease (AD) diagnosis and management. The team has developed a cutting-edge blood test for the early detection of AD and mild cognitive impairment (MCI), surpassing remarkable accuracy rates of over 96% and 87% respectively.
February 19th, 2024 — Source

Health — Alzheimers — February 16th, 2024

Exploring the potential of a novel PET-tracer in spotting early signs of Alzheimer's disease
Researchers at Karolinska Institutet have made exciting discoveries about Alzheimer's disease, a common form of dementia affecting millions of people around the world. In a study published in Alzheimer's & Dementia, they have explored the potential of novel synaptic PET-tracer UCB-J as an important early diagnostic biomarker/tool for Alzheimer's disease.
February 16th, 2024 — Source

New genetic therapy shows promise for motor neuron disease and frontotemporal dementia
Macquarie University neuroscientists have developed a single-dose genetic medicine that has been proven to halt the progression of both motor neuron disease (MND) and frontotemporal dementia (FTD) in mice—and may even offer the potential to reverse some of the effects of the fatal diseases.
February 16th, 2024 — Source

Health — Alzheimers — February 14th, 2024

New study confirms double the risk of dementia after mouth herpes simplex virus
People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study from Uppsala University confirms previous research on whether herpes can be a possible risk factor for dementia.
February 14th, 2024 — Source

Health — Alzheimers — February 12th, 2024

Protein biomarkers predict dementia 15 years before diagnosis, according to new study
In the largest study of its kind, scientists have shown how protein "biomarkers" predict dementia 15 years before diagnosis.
February 12th, 2024 — Source

Protein modifications found to be key influencers in neurodegenerative diseases
Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the accumulation of misfolded protein aggregates in the brain, known as amyloid fibrils, which disrupt normal cell function and eventually lead to cell death.
February 12th, 2024 — Source

Health — Alzheimers — February 9th, 2024

Dementia care costs can quickly burn through people's savings: Study
Dementia care can eat through the savings of cash-strapped seniors, a new study warns.
February 9th, 2024 — Source

Language barriers could contribute to higher aggression in people with dementia
Researchers from ECU's Center for Research in Aged Care and HammondCare's The Dementia Center noted that behaviors and psychological symptoms of dementia (BPSD), such as agitation and aggression, are common; however, its presentation may be influenced by the cultural background of the person.
February 9th, 2024 — Source

Men using erectile dysfunction drugs less likely to develop Alzheimer's disease
Drugs commonly used to treat erectile dysfunction may reduce the risk of Alzheimer's disease, finds a new study led by UCL researchers.
February 9th, 2024 — Source

Protein accumulation on fat droplets implicated in late-onset Alzheimer's disease
UNC School of Medicine researcher Sarah Cohen, Ph.D., and Ian Windham, a former Ph.D. student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE)—the biggest genetic risk factor for late-onset Alzheimer's disease.
February 9th, 2024 — Source

Health — Alzheimers — February 7th, 2024

Do lifestyle factors affect late-life cognition and dementia pathology impact?
In a recent study published in the journal JAMA Neurology, scientists from the Rush University Medical Center in Chicago, United States, investigated whether brain pathology related to dementia, such as cerebrovascular pathology, phosphorylated tau fibril tangles, and &beta-amyloid accumulation, modify the association between healthy lifestyle choices and cognition during the later years in life.
February 7th, 2024 — Source

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease
The drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study published in Neurology. The study does not prove that erectile dysfunction drugs reduce the risk of Alzheimer's disease. It only shows an association.
February 7th, 2024 — Source

Health — Alzheimers — February 5th, 2024

Hearing impairment may lead to depression, isolation, dementia
If you've ever found yourself repeating parts of a conversation for an older person or walking into a room where they've turned the TV up full blast, you might have discovered more than just a typical byproduct of aging.
February 5th, 2024 — Source

Health — Alzheimers — February 2nd, 2024

How a natural protein can help fight Alzheimer's disease
A new study published in Nature Communications gives insights into the underlying mechanisms of the formation of protein clumps in Alzheimer's disease. The study, led by researchers from Karolinska Institutet, could pave the way for new treatments for this devastating neurodegenerative disorder.
February 2nd, 2024 — Source

What are the early signs of dementia, and how does it differ from normal aging?
Forgetting names and misplacing items happen to us all, more so as we age.
February 2nd, 2024 — Source

Health — Alzheimers — February 1st, 2024

Dementia risk can be the highest in the first year after stroke
Having a stroke may significantly increase the risk of developing dementia. The risk of dementia was the highest in the first year after a stroke and remained elevated over a period of twenty years, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2024.
February 1st, 2024 — Source

Research finds risk of dementia nearly three times higher the first year after a stroke
Having a stroke may significantly increase the risk of developing dementia.
February 1st, 2024 — Source

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease
While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory. What is needed are more treatment options targeted to restore memory, said Buck Institute for Research on Aging Assistant Professor Tara Tracy, Ph.D., the senior author of a study that proposes an alternate strategy for reversing the memory problems that accompany Alzheimer's disease and related dementias.
February 1st, 2024 — Source

Health — Alzheimers — January 31st, 2024

Abnormal proteins found in the spinal fluid of people with ALS and frontotemporal dementia
Proteins could serve as biomarkers that improve diagnosis and guide the development of novel therapies.
January 31, 2024 — Source

Biogen pulls controversial Alzheimer's drug Aduhelm
A controversial Alzheimer's drug that was trumpeted as the first to ever treat the cognitive decline associated with the devastating brain disorder has been pulled from the market, its maker Biogen announced Wednesday.
January 31, 2024 — Source

Computer-designed proteins allow for tunable hydrogels that can form both inside and outside of cells
When researchers want to study how COVID makes us sick, or what diseases such as Alzheimer's do to the body, one approach is to look at what's happening inside individual cells. Researchers sometimes grow the cells in a 3D scaffold called a "hydrogel." This network of proteins or molecules mimics the environment the cells would live in inside the body.
January 31, 2024 — Source

Meat-based and processed foods foods linked to Alzheimer's
A study has found a strong link between Alzheimer's disease and the daily consumption of meat-based and processed foods. Researchers at Bond University came to the conclusion after examining the diets of 438 Australians—108 with Alzheimer's and 330 in a healthy control group.
January 31, 2024 — Source

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings
The AD-RIDDLE programme will offer healthcare professionals a suite of validated solutions for timely detection and diagnosis of Alzheimer's disease and dementias, to match individuals with the right interventions at the right time, enabling people to better understand what they can do to reduce risk and prevent cognitive decline.
January 31, 2024 — Source

Researchers hack neurons' internal clocks to accelerate the study of neurological diseases
The neurons that make up our brains and nervous systems mature slowly over many months. And while this may be beneficial from an evolutionary standpoint, the slow pace makes growing cells to study neurodegenerative and neurodevelopmental diseases—like Parkinson's disease, Alzheimer's disease, and autism—in the laboratory quite challenging.
January 31, 2024 — Source

Study finds 1 in 10 veterans diagnosed with dementia may instead have cognitive decline from cirrhosis
As many as 10% of older U.S. veterans diagnosed with dementia may suffer instead from reversible cognitive decline caused by advanced liver disease, according to an analysis from the Virginia Commonwealth University's School of Medicine and the Richmond VA Medical Center.
January 31, 2024 — Source

Health — Alzheimers — January 29th, 2024

Alzheimer's disease acquired from historic medical treatments
Five cases of Alzheimer's disease are believed to have arisen as a result of medical treatments decades earlier, reports a team researchers.
January 29, 2024 — Source

Overcoming the stigma: Study recommends steps to move past barriers of brain health conversation
Approximately four of five primary care clinicians consider themselves on the front lines of brain health. In the U.S., clinicians are the first point of contact for patients worried about memory loss and are most likely the first to detect and evaluate patients experiencing mild cognitive impairment, Alzheimer's disease or related dementias.
January 29, 2024 — Source

Re-energizing mitochondria to treat Alzheimer's disease
Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer's disease, the ability to make energy is compromised, and the connections between nerve cells (called synapses) eventually come apart and wither, causing new memories to fade and fail.
January 29, 2024 — Source

Researchers discover Alzheimer's disease cases acquired from past medical treatments
Five cases of Alzheimer's disease are believed to have arisen as a result of medical treatments decades earlier, reports a team of UCL and UCLH researchers.
January 29, 2024 — Source

Health — Alzheimers — January 26th, 2024

Nasopharyngeal lymphatics found to be crucial for draining cerebrospinal fluid from the brain
In a study published in Nature, South Korean researchers led by Director Koh Gou Young of the Center for Vascular Research within the Institute for Basic Science (IBS) have uncovered a distinctive network of lymphatic vessels at the back of the nose that plays a critical role in draining cerebrospinal fluid (CSF) from the brain.
January 26, 2024 — Source

New tool helps predict progression of Alzheimer's
About 55 million people worldwide are living with dementia, according to the World Health Organization. The most common form is Alzheimer's disease, an incurable condition that causes brain function to deteriorate.
January 26, 2024 — Source

Health — Alzheimers — January 24th, 2024

Protein TDP-43 keeps genetic zombies at bay: New insights into neurodegenerative disease mechanisms
A new Cell Reports paper from Bing Yao's lab in Emory's Department of Human Genetics provides insights into mechanisms underlying several neurodegenerative diseases, such as ALS (amyotrophic lateral sclerosis) and Alzheimer's.
January 24, 2024 — Source

Health — Alzheimers — January 22nd, 2024

A newly characterized form of tau may be involved in initiating Alzheimer's disease
The tau protein accumulates in abnormal shapes in the brains of individuals with Alzheimer's disease (AD), but the early steps of tau misfolding and aggregation are unknown.
January 22, 2024 — Source

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity
In a recent study published in Nature Communications, a group of researchers explored how Death Induced by Survival gene Elimination (DISE) through the analysis of ribonucleic acid (RNA)-induced silencing complex (RISC)-bound short RNAs (R-sRNAs) in Alzheimer's disease (AD) models, influences neuronal survival and correlates with neurotoxicity in AD.
January 22, 2024 — Source

How To Restore Your Facebook Account If You Can't Get Into Your Old Email Address
Most of us have had our Facebook accounts for so long that we may not even know what email address we used to sign up, or if we do know the address, we may no longer have access to it. For example, if you opened your account with a work or college issued email address, you may have lost access to the one associated with your Facebook account post-graduation or after changing jobs
January 22, 2024 — Source

Neuroticism Isn't Funny and May Impact Your Health
In the 1979 comedy Manhattan, Mary (played by Diane Keaton) tells Isaac (Woody Allen) to vent his frustrations so they can finally get their feelings out in the open. “I don't get angry,” Isaac replies. “I grow a tumor instead.”
January 22, 2024 — Source

Thinning brain tissue predicts dementia up to a decade before symptoms
A ribbon of brain tissue called cortical gray matter grows thinner in people who go on to develop dementia, and this appears to be an accurate biomarker of the disease five to 10 years before symptoms appear, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported.
January 22, 2024 — Source

Thinning of brain region may signal dementia risk 5–10 years before symptoms
A ribbon of brain tissue called cortical gray matter grows thinner in people who go on to develop dementia, and this appears to be an accurate biomarker of the disease five to 10 years before symptoms appear, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) report.
January 22, 2024 — Source

Health — Alzheimers — January 19th, 2024

Don't look back: The aftermath of a distressing event is more memorable than the lead-up
The moments that follow a distressing episode are more memorable than the moments leading up to it
January 19, 2024 — Source

New links revealed between late-onset Alzheimer's disease and the immune system
Researchers have revealed new links between Alzheimer's disease and the blood-brain barrier, finding connections between variants of a gene called EphA1 and the disease.
January 19, 2024 — Source

Treating Alzheimer's, Parkinson's, type 2 diabetes by eliminating protein aggregation in brain, pancreas
Purdue University researchers have taken the first steps to treat Alzheimer's disease, Parkinson's disease and Type 2 diabetes by creating multiple patent-pending compounds shown to inhibit protein aggregation associated with those diseases.
January 19, 2024 — Source

Understanding the impact of a dementia board game
Specialist dementia researchers from the University of Liverpool have seen positive initial findings when analyzing the outcomes of a board game that shines a light on dementia inequalities. Their paper, "Co-producing a boardgame to learn and engage about dementia inequalities: First impacts on knowledge in the general population," was published in Health Expectations.
January 19, 2024 — Source

Health — Alzheimers — January 12th, 2024

Study reveals function of little-understood synapse in the brain
New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma.
January 12, 2024 — Source

The FDA has reportedly approved an AI product that predicts cognitive decline
BrainSee assigns a score forecasting the advancement of memory loss within five years.
January 12, 2024 — Source

Health — Alzheimers — January 13th, 2024

Differences in cerebrospinal fluid of Alzheimer's patients suggests possibility of variants
A large team of neuroscientists and neurodegenerative disease specialists affiliated with multiple entities across the Netherlands, working with colleagues from the U.S., Belgium, the U.K. and Sweden, has found five categories of fluid surrounding the brain in Alzheimer's patients.
January 13, 2024 — Source

Health — Alzheimers — January 11th, 2024

Flagging dementia patients for better hospital care
Cedars-Sinai investigators are using electronic health records to identify hospitalized patients likely to have dementia. The method they developed, detailed in a study published in the Journal of the American Geriatrics Society, is designed to help medical staff tailor care to best serve these patients.
January 11, 2024 — Source

Health — Alzheimers — January 10th, 2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe
Researchers have created the world's largest ancient human gene bank by analyzing the bones and teeth of almost 5,000 humans who lived across western Europe and Asia up to 34,000 years ago.
January 10, 2024 — Source

'Exhausted' immune cells may drive Alzheimer's
Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually exhibiting signs of Alzheimer's disease not unlike that of many elderly humans.
January 10, 2024 — Source

Study: Amyloid-&beta protein affects cognitive decline after small-sized cerebral infarction
A research team has confirmed that brain amyloid-&beta (A&beta) deposition, a biomarker for Alzheimer's disease, is an essential predictor for post-stroke cognitive impairment (PSCI) development and cognitive decline after small-sized cerebral infarction.
January 10, 2024 — Source

Health — Alzheimers — January 9th, 2024

Different biological variants discovered in Alzheimer's disease
Dutch scientists have discovered five biological variants of Alzheimer's disease, which may require different treatments. As a result, previously tested drugs may incorrectly appear to be ineffective or only minimally effective. This is the conclusion of researcher Betty Tijms and colleagues from Alzheimer Center Amsterdam, Amsterdam UMC and Maastricht University.
January 9, 2024 — Source

Examining molecular biomarkers to diagnose vascular cognitive impairment and dementia
A recent study from UNSW Sydney's Center for Healthy Brain Aging (CHeBA) suggests that the research pace into understanding biomarkers for the diagnosis of vascular cognitive impairment and dementia needs to be accelerated.
January 9, 2024 — Source

Photostimulation of lymphatic clearance of &beta-amyloid: A new strategy for Alzheimer's disease therapy
Alzheimer's disease (AD) is an age-related neurodegenerative disorder. &beta-amyloid (A&beta) deposition in the brain is a crucial contributor to the pathogenesis of AD, mitigating excessive cerebral A&beta burden has been considered as a possible therapeutic strategy for AD.
January 9, 2024 — Source

Health — Alzheimers — January 8th, 2024

A new platform to fast-track lifesaving brain research
An international team led by Australian researchers has developed a platform that could transform neuroimaging data analysis worldwide. The Neurodesk platform will enable scientists to accelerate research on conditions such as epilepsy, dementia, schizophrenia and traumatic brain injury by enabling faster processing and analysis of neuroimaging data.
January 8, 2024 — Source

Bariatric surgery may mitigate the natural history of cognitive decline in people with obesity
Within the next 10 years, it's projected that up to 50% of United States adults will be affected by obesity, which is associated with cognitive impairment and dementia.
January 8, 2024 — Source or Source

'Disease in a dish' model sheds light on the triggers for some forms of dementia
New understanding of a gene that is linked to some forms of dementia and other age-related diseases gives scientists fresh hope that action can be taken against these diseases long before the onset of symptoms.
January 8, 2024 — Source

High-quality nursing home dementia care is not only a matter of adding staff, says study
Additional staffing alone will not be sufficient to bridge the quality-of-care and health outcome disparities among nursing home facilities with varying percentages of residents with dementia, according to a first-of-its-kind study led by the University of California, Irvine. Specialized training, an easy-to-navigate environment and staff stability are also critical to meeting the unique challenges presented by this population.
January 8, 2024 — Source

Health — Alzheimers — January 5th, 2024

Hearing loss increases the risk of dementia
In a new study featuring data from 573,088 people, researchers have found a link between hearing loss and the development of dementia. The study is the largest of its kind to date.
January 5, 2024 — Source

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