The MerchantStoreDirectoryAbout UsAdd-siteLink to Us

 

428 Health - Alzheimer Resources

Misc. - Numbers

'5-D protein fingerprinting' with nanopores could give insights into Alzheimer's, Parkinson's
In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid.
January 17, 2017
Read More


Misc. - A

A blood test could predict the risk of Alzheimer's disease
High-tech analysis picks up minuscule bits of amyloid-beta floating in plasma
February 1, 2018
Read More


A decline in navigational skills could predict neurodegenerative disease
Changes in how humans map their surroundings and construct and follow directions as they age have been understudied compared to effects on memory and learning. However, age-related declines in navigational ability are independent of those more well-known cognitive downturns, and could form the basis for tools for the early diagnosis of Alzheimer's disease.
August 30, 2017
Read More


A Healthy Diet May Help Ward Off Dementia
New studies suggest that, yes, eating right could boost your brain function
July 17, 2017
Read More


A Healthy Middle-Aged Heart May Protect your Brain
Dementia expert says take up heart-healthy habits sooner rather than later
April 11, 2017
Read More


A high-salt diet produces dementia in mice
A high-salt diet reduces resting blood flow to the brain and causes dementia in mice.
January 16, 2018
Read More


A new view of twisted proteins could help scientists understand Alzheimer's
A critical molecule in the neurodegenerative disease has finally been mapped.
July 14, 2017
Read More


A salad a day may keep memory problems away, study says
A new study published yesterday in Neurology, the online medical journal of the American Academy of Neurology, Neurology, suggested that consuming about one serving of leafy vegetables per day may be associated with a slower rate of brain aging.
December 21, 2017
Read More


A star is born: Lesser-known brain cell takes center stage
A new method efficiently grows human astrocytes in a dish, advancing studies of stroke, Alzheimer's and depression.
June 6, 2017
Read More


AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies
AbbVie, a global biopharmaceutical company, and Voyager Therapeutics, Inc., a clinical-stage gene therapy company, today announced that they have entered into an exclusive strategic collaboration and option agreement to develop and commercialize vectorized antibodies directed against tau for the treatment of Alzheimer's disease and other neurodegenerative diseases.
February 20, 2018
Read More


Action-consequence feature of unitization strategy improves memory in older adults, study shows
The next time you hear about the possibility of rain on the weather forecast, try imagining the umbrella tip being lodged in your home's door lock, blocking you from locking it. This mental exercise could prevent you from leaving home without an umbrella.
August 11, 2017
Read More


ActuRx and Insillico Medicine collaborate to prevent, treat age-related illnesses
Can big data and financial engineering cure Cancer, Alzheimer's, and other age-related illnesses? ActuRx and Insillico Medicine think so. Both companies have developed complementary techniques to filter potential solutions against aging illnesses and now they think they can convert financial masses into health improvements worldwide.
July 4, 2017
Read More


AD polygenic risk score could identify younger population with mild cognitive impairment
For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer's disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI is considered a precursor to AD.
March 5, 2018
Read More


Advances in brain imaging settle debate over spread of key protein in Alzheimer's
Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads throughout the brain in Alzheimer's disease -- and hence that blocking its spread may prevent the disease from taking hold.
January 5, 2018
Read More


Aerobic exercise may be key for Alzheimer's prevention
New research recently published in the Journal of the American Geriatrics Society explores the benefits of exercising for delaying Alzheimer's disease.
January 30, 2018
Read More


Aerobic exercise may mildly delay, slightly improve Alzheimer's symptoms
Geriatrics experts have suggested that exercising can improve brain health in older adults. However, not all studies of exercise and older adults have proven the benefits of exercise. A team of researchers designed a study to learn whether exercise could delay or improve AD symptoms.
January 26, 2018
Read More


African plant extract could pave way for new drug to treat Alzheimer's disease
A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer's disease, researchers at The University of Nottingham have found.
June 19, 2017
Read More


Air pollution may lead to dementia in older women
Tiny, dirty airborne particles called PM2.5 invade the brain and wreak havoc, study suggests
January 31, 2017
Read More


Alzheimer's Association
Our vision is a world without Alzheimer's disease
Provides Information
Read More


Alzheimer's brain damage halved with gene-targeting compound
More and more studies are starting to point to the APOE gene as a gateway to halting the progression of Alzheimer's disease. But few have actually targeted APOE in living animals. New research uses a molecule against APOE in mice, and the treatment could reduce brain damage by half.
December 6, 2017
Read More


Alzheimer's could be diagnosed early with sniff tests
Testing the sense of smell of people at a high risk of Alzheimer's disease might help to provide an early diagnosis, a new study suggests.
August 17, 2017
Read More


Alzheimer's damage in mice reduced with compound that targets APOE gene
APOE is major Alzheimer's risk gene
December 6, 2017
Read More


Alzheimer's Deaths Jump 55 Percent: CDC
More patients also dying at home, with the caregiving burden falling on loved ones
May 25, 2017
Read More


Alzheimer's disease also affects small blood vessels
A research conducted by the UAB demonstrates that mice suffering from this disease also have substantial malfunctions in small blood vessels, important in nourishing different organs and tissues and in regulating blood pressure, and which mainly affects females.
March 16, 2018
Read More


Alzheimer's disease could be triggered by breakdowns from other parts of the body
Alzheimer's disease, the leading cause of dementia, has long been assumed to originate in the brain. But research from the University of British Columbia and Chinese scientists indicates that it could be triggered by breakdowns elsewhere in the body.
October 31, 2017
Read More


Alzheimer's Disease is 'Whole Body' Problem
Scientists attached a healthy mouse to one carrying a mutant human gene that produces high levels of the protein called amyloid beta. Both ended up with Alzheimer's (via University of British Columbia)
October 31, 2017
Read More


Alzheimer's disease likely not caused by low body mass index
Research clarifies past studies on weight, common cause of dementia
May 9, 2017
Read More


Alzheimer's disease might be a 'whole body' problem
Amyloid-beta can travel, cancer-like, to brain from other parts of body
October 31, 2017
Read More


Alzheimer's disease progression predicted by gene mutation
Research, published today in the journal Neurology, describes how mutations in a specific gene that codes for a neural growth factor appear to predict how quickly memory loss will progress in people with Alzheimer's disease.
May 4, 2017
Read More


Alzheimer's disease study links brain health, physical activity
People at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have healthy patterns of glucose metabolism in their brain, according to a new study.
June 22, 2017
Read More


Alzheimer's disease: Family history may explain puzzling link to metabolic gene
For years, scientists have contemplated the link between the risk of developing Alzheimer's disease and a metabolic gene called TOMM40, which affects the function of mitochondria, the components inside cells that provide them with energy. Studies have produced mixed results, giving rise to much frustration. However, a new study now finds that a third factor, family history of Alzheimer's, may be the missing link.
May 23, 2017
Read More


Alzheimer's disease: Scientists close in on how it starts and how to stop it
Scientists identified a sequence of events involving immune cells and proteins that become abnormal in Alzheimer's disease. They suggest that this could be the starting point for the brain-wasting disorder and they identify two proteins that might serve as drug targets for stopping or even reversing its symptoms.
August 31, 2017
Read More


Alzheimer's disease: Targeting enzyme may reverse memory loss
A new study has suggested that it may be possible to reverse the memory loss that occurs in Alzheimer's disease with drugs that selectively block the ability of the HDAC2 enzyme to interfere with the communication between brain cells.
August 9, 2017
Read More


Alzheimer's Drug May Help Combat Effects of Teen Drinking
Can an Alzheimer's drug help combat the effects of teenage binge drinking?
February 20, 2018
Read More


Alzheimer's drug repairs brain damage after alcohol binges in rodents
Drug appears to reverse structural and genetic brain changes that affect memory, learning
February 15, 2018
Read More


Alzheimer's drug turns back clock in powerhouse of cell
Researchers identify molecular target of J147, which is nearing clinical trials to treat Alzheimer's disease
January 9, 2018
Read More


Alzheimer's gene poses both risk and benefits
Study suggests role of inflammation in brain disease is complicated
October 9, 2017
Read More


Alzheimer's protein can travel from blood to build up in the brain
Movement of amyloid-beta could suggest new ways to treat the disease
November 6, 2017
Read More


Alzheimer's related brain changes could start at 40
Scientists may have advanced our understanding of the brain mechanisms behind Alzheimer's disease, after uncovering a process that precedes the buildup of toxic proteins that is a hallmark of the condition.
February 5, 2018
Read More


Alzheimer's Treatment Works in Mice, But What About Humans?
Great news: Scientists are making progress in preventing Alzheimer's among mice. Humans, however, are another story.
February 8, 2018
Read More


Alzheimer's: Brain's protective mechanism revealed
Buildups of "clumpy" proteins in the brain are well-known hallmarks of Alzheimer's, but not everyone who has them goes on to develop this neurodegenerative disease. Why is that? New research investigates.
October 26, 2017
Read More


Alzheimer's: Sex matters, but so does age
A new meta-analysis corrects previous knowledge on sex-specific risk of developing Alzheimer's disease. After analyzing data from almost 58,000 individuals of both sexes, the researchers suggest that women are more at risk than men during a crucial 10-year span: between ages 65 and 75.
August 29, 2017
Read More


Alzheimer's: Low serotonin levels may drive development
Could Alzheimer's disease be caused by low levels of serotonin, the brain chemical known to affect mood and sleep? New research investigates.
August 15, 2017
Read More


Alzheimer's: Preserving neurons may prevent depression, cognitive decline
A compound that stopped brain cells from dying in an animal model of Alzheimer's disease could lead to new treatments for people with the condition who live with depression and deterioration in memory and thinking.
November 7, 2017
Read More


Alzheimer's: Protein from outside the brain may be involved
A study in mice has discovered that amyloid beta, the protein that causes one of the hallmarks of Alzheimer's disease in the brain, may also come from other parts of the body.
October 31, 2017
Read More


Alzheimer's: 'Triple-action' diabetes drug shows promise as treatment
Scientists in the United Kingdom and China find that a new drug for type 2 diabetes may protect the brain from damage caused by Alzheimer's disease, after testing it in mice.
January 2, 2018
Read More


Alzheimer's: Word processing duration may predict onset
Recent research published in the journal NeuroImage Clinical suggests that the time it takes for someone to process written words may be a reliable predictor of their risk of developing Alzheimer's disease.
October 20, 2017
Read More


Another Alzheimer's Drug Fails; Scientists Stymied
As more experimental drugs fail to stop Alzheimer's from destroying human memory, experts now wonder whether research into the devastating brain disease has been marching in the wrong direction.
January 25, 2018
Read More


Anti-seizure drug could have beneficial effect in patients with mild Alzheimer's disease
In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer's disease. Patients with Alzheimer's disease have an increased risk of epilepsy and nearly half may experience subclinical epileptic activity -- disrupted electrical activity in the brain that doesn't result in a seizure but which can be measured by electroencephalogram (EEG) or other brain scan technology.
June 23, 2017
Read More


Anti-epilepsy drug restores normal brain activity in mild Alzheimer's disease
Feasibility study suggests suppressing seizure-like activity may help patients
June 23, 2017
Read More


Antidepressant use increases hip fracture risk among elderly
Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer's disease, according to a new study. the increased risk was highest at the beginning of antidepressant use and remained elevated even 4 years later.
January 11, 2017
Read More


Antidepressant use increases risk of head injuries among persons with Alzheimer's disease
Antidepressant use is associated with an increased risk of head injuries and traumatic brain injuries among persons with Alzheimer's disease, according to a new study. Antidepressant use has previously been linked with an increased risk of falls and hip fractures, but the risk of head injuries has not been studied before.
August 9, 2017
Read More


Antidepressant use linked to higher risk of head injuries among persons with Alzheimer's disease
Antidepressant use is associated with an increased risk of head injuries and traumatic brain injuries among persons with Alzheimer's disease, according to a new study from the University of Eastern Finland. Antidepressant use has previously been linked with an increased risk of falls and hip fractures, but the risk of head injuries has not been studied before.
August 9, 2017
Read More


Antiulcer drugs do not increase risk of Alzheimer's disease
The use of proton pump inhibitors does not increase the risk of Alzheimer's disease, according to a recent study. Proton pump inhibitors are a type of antiulcer drug that is commonly used among older people.
August 7, 2017
Read More


Any Alzheimer's Breakthrough Could Bypass Millions
Even if researchers were to find a groundbreaking new treatment for Alzheimer's disease, millions of people might not benefit from it, new research reveals.
November 15, 2017
Read More


Artificial intelligence predicts dementia before onset of symptoms
New technology could improve patient care, accelerate search for Alzheimer's treatments
August 22, 2017
Read More


Artificial intelligence technique recognizes signatures of dementia two years before onset
Imagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and their families time to plan and manage treatment and care. Thanks to artificial intelligence research conducted at McGill University, this kind of predictive power could soon be available to clinicians everywhere.
August 22, 2017
Read More


Autoimmune disease discovery could spark new treatments
Researchers have developed a drug-like compound that inhibits key protein
November 21, 2017
Read More


Misc. - B

Bad sleep increases Alzheimer's-related brain proteins
Researchers from the United States and the Netherlands have shown that bouts of bad sleep can significantly increase the amount of tau and amyloid beta in the brain, which are linked to a higher risk of Alzheimer's disease.
July 11, 2017
Read More


Being unaware of memory loss predicts Alzheimer's disease, new study shows
While memory loss is an early symptom of Alzheimer's disease, its presence doesn't mean a person will develop dementia. A new study has found a clinically useful way to predict who won't develop Alzheimer's disease, based on patients' awareness of their memory problems.
October 10, 2017
Read More


Benzodiazepines increase mortality in persons with Alzheimer's disease
Benzodiazepine and related drug use is associated with a 40 percent increase in mortality among persons with Alzheimer's disease, according to a new study.
November 20, 2017
Read More


Benzodiazepines, related drugs increase stroke risk among persons with Alzheimer's disease
The use of benzodiazepines and benzodiazepine-like drugs was associated with a 20 per cent increased risk of stroke among persons with Alzheimer's disease, shows a recent study. Benzodiazepines were associated with a similar risk of stroke as benzodiazepine-like drugs.
January 16, 2017
Read More


Better support needed for thousands of informal dementia carers
Directly involving the thousands of family members and friends who serve as 'informal carers' for people with dementia in the evaluation of patients' symptoms and behavior could offer improved insights for healthcare professionals and help alleviate feelings of stress, guilt and isolation felt by many who fulfill these duties, a new study has found.
February 2, 2018
Read More


Bilingualism could offset brain changes in Alzheimer's
A study sheds light on how language history relates to brain plasticity
February 6, 2018
Read More


Bill Gates Donates $50 Million to Alzheimer's Research
Bill Gates says he will provide $50 million for research into efforts to find a cure for Alzheimer's disease.
November 13, 2017
Read More


Bill Gates putting up $100 million to fight Alzheimer's
Billionaire Microsoft founder is investing a chunk of his own money to fund research into Alzheimer's disease.
November 13, 2017
Read More


Blood screening tests could predict Alzheimer's disease
Researchers from Missouri reveal that blood test screening may identify markers of Alzheimer's disease before individuals begin to experience memory loss and confusion. This finding is a significant step toward predicting disease risk.
July 19, 2017
Read More


Blood Thinners May Protect A-Fib Patients' Brains
Blood thinners may pull double duty for people with the heart rhythm disorder atrial fibrillation: New research suggests they help prevent dementia as well as stroke.
October 26, 2017
Read More


Blood thinners slash dementia risk in A-fib patients
New research published in the European Heart Journal suggests that blood-thinning drugs such as warfarin may protect not only against stroke, but also against dementia in people who have atrial fibrillation.
October 25, 2017
Read More


Blood vessels also affected by Alzheimer's disease
New research demonstrates that mice suffering from this disease also have substantial malfunctions in small blood vessels, important in nourishing different organs and tissues and in regulating blood pressure, and which mainly affects females.
March 16, 2018
Read More


BMI status of older adults influences benefits accrued from memory training, study finds
In the first study to compare the results of cognitive training by body mass index (BMI) category, scientists from the Indiana University Center for Aging Research found that memory training provided only one-third the benefit to older adults with obesity than the benefit it provided to older adults without obesity.
January 10, 2017
Read More


BMI: A double-edged sword in your risk of dementia
An analysis of international data on more than a million people who were followed over time confirms two links between BMI and dementia -- one ties midlife obesity to higher risk, and the other ties being underweight near disease onset to higher risk.
December 4, 2017
Read More


Body clock disruptions may be an early sign of Alzheimer's
New research published in JAMA Neurology suggests that those people whose memory is intact and who do not show any signs of Alzheimer's can have disrupted circadian rhythms -- which may be a very early sign of Alzheimer's.
January 30, 2018
Read More


Body clock disruptions occur years before memory loss in Alzheimer's
People with Alzheimer's disease have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Researchers have found that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer's.
January 26, 2018
Read More


'Boot Camp' helps Alzheimer's, dementia caregivers take care of themselves, too
Gary Carmona thought he could do it all. He's run companies and chaired nonprofit boards. But since his wife was diagnosed with dementia, Carmona, 77, has felt overwhelmed.
May 9, 2017
Read More


'Brain training' app found to improve memory in people with mild cognitive impairment
A 'brain training' game could help improve the memory of patients in the very earliest stages of dementia, suggests a new study.
July 3, 2017
Read More


Brain activity higher in women than men, study finds
Some brain disorders are much more common in women than men, but why? A new study may help to shed light on this sex difference, after finding that many brain regions are much more active in women.
August 8, 2017
Read More


Brain 'Pacemaker' Could Lessen Alzheimer's Effects
For decades, LaVonne Moore hosted talk shows on WBCO, the Bucyrus, OH, radio station that she and her husband, Tom Moore, founded in 1962. About 5 years ago, she asked her husband to take her off the air.
February 2, 2018
Read More


Brain stimulation enhances long-term memory for first time
Scientists find that directly stimulating the amygdala can improve memory the next day, marking the first time ever that electrical stimulation has boosted memory for more than a few minutes.
December 19, 2017
Read More


Brain's immune cells linked to Alzheimer's, Parkinson's, schizophrenia
Scientists conducted a vast microglia survey, revealing links to neurodegenerative diseases and psychiatric illnesses.
May 31, 2017
Read More


Brain's power to adapt offers short-term gains, long-term strains
Like air-traffic controllers scrambling to reconnect flights when a major hub goes down, the brain has a remarkable ability to rewire itself after suffering an injury. However, maintaining these new connections between brain regions can strain the brain's resources, which can lead to serious problems later, including Alzheimer's Disease, according to researchers.
April 24, 2017
Read More


Brain's response to mid-life surge in cell aging starts or ends a path to dementia
Researchers have discovered a previously unknown characteristic of brain-cell aging that could help detect late-onset Alzheimer's disease decades before symptoms begin.
October 30, 2017
Read More


Brain-training games 'do not boost cognition'
The past decade has seen a rise in popularity of brain-training games that claim to improve a range of mental skills. However, a recent study that measured brain activity, decision-making, and cognitive ability found that playing commercial brain games offered no benefits above those of playing online video games.
July 12, 2017
Read More


Breakdown of brain cells' metabolic collaboration linked to Alzheimer's disease
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration.
September 29, 2017
Read More


Butterflies of the soul: Developmental origins of interneurons
A new study reveals how interneurons, dubbed 'the butterflies of the soul,' emerge and diversify in the brain. The findings may help inform the development of new classes of drugs for diseases such as autism, schizophrenia and Alzheimer's.
March 30, 2018
Read More


Misc. - C

Caffeine may be able to block inflammation, new research says
This could help explain why caffeine is correlated with health benefits
January 16, 2017
Read More


Can A Zap to the Brain Recharge Your Memory?
Carefully targeted deep brain stimulation might one day enhance long-term memory, a small study suggests.
December 19, 2017
Read More


Can Air Pollution Heighten Alzheimer's Risk?
Fine particles from power plants and cars may be to blame for about 20 percent of cases, study suggests
February 1, 2017
Read More


Can beets tackle Alzheimer's at its root?
Alzheimer's disease is characterized by beta-amyloid plaques in the brain that disrupt the normal functioning of neurons. Could a common vegetal pigment provide the fix?
March 22, 2018
Read More


Can we end damaging dementia psychosis cycle?
A new research report calls for a change in approach in the treatment of psychosis in dementia, to find alternatives to highly damaging antipsychotics.
September 29, 2017
Read More


Cancer-protecting enzyme is 'also promoting its growth'
The NEIL3 enzyme has long been known to repair 'day-to-day' oxidative damage to DNA that is implicated in diseases of ageing, including dementia and cancer.
December 12, 2017
Read More


Cell therapy could improve brain function for Alzheimer's disease
Transplanting a special type of neuron into the brain restores cognitive functions in Alzheimer's models, shows a new study
March 15, 2018
Read More


Cellular recycling caught in the act
Researchers have observed a normal physiological process, called "self-eating", that cells use to recycle their components. They developed an accurate technique that visualizes how mitochondria, cells' energy factories, are fused with lysosomes, cells' recycling machines, in order to get material destroyed and recycled. Since irregularities in this mechanism can lead to Alzheimer's, Parkinson's, and other complications, this research could help future advances in degenerative brain disease diagnosis and drug development.
February 19, 2018
Read More


Circadian rhythm disruptions occur much earlier in people at risk of Alzheimer's
People with Alzheimer's disease are known to have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Now, new research at Washington University School of Medicine in St. Louis indicates that such circadian rhythm disruptions also occur much earlier in people whose memories are intact but whose brain scans show early, preclinical evidence of Alzheimer's.
January 26, 2018
Read More


Cognitive decline: Is low blood sodium a risk factor?
Low sodium levels in the blood have been linked to declines in cognitive function among otherwise healthy older men in a new study, which has now been published in the Clinical Journal of the American Society of Nephrology.
February 9, 2018
Read More


Cognitive training holds potential to strengthen the aging brain
Relentless cognitive decline as we age is worrisome, and it is widely thought to be an unavoidable negative aspect of normal aging. Researchers at the Center for BrainHealth at The University of Texas at Dallas, however, say their research could provide new hope for extending our brain function as we age.
January 23, 2018
Read More


Combustion-derived nanoparticles in brain cells concern for Alzheimer's disease development
A new study by researchers at the University of Montana, Universidad del Valle de Mexico, Instituto Nacional de Pediatría, Boise State, and Universidad Nacional Autónoma de Mexico, heightens concerns over the detrimental short- and long-term impact of airborne iron-rich strongly magnetic combustion-derived nanoparticles (CDNPs) present in young urbanites' brains.
June 8, 2017
Read More


Common cause of both neurological diseases such as dementia and motor neuron diseases
Currently, most scientists do not see a link between ALS and Alzheimer's disease, frontotemporal dementia (FTD), or other dementias. new research confirms the relevance of a certain neurotoxic pathway. the article also confirms TDP-43 inhibition as a viable therapeutic option for the treatment of neurologic disorders, including Alzheimer disease.
January 23, 2017
Read More


Common sedatives linked to increased risk of pneumonia in people with Alzheimer's disease
Commonly used sedatives called benzodiazepines are associated with an increased risk of pneumonia when used in people with Alzheimer's disease, according to a study.
April 10, 2017
Read More


Common sedatives raise pneumonia risk in Alzheimer's patients
New research suggests that a sedative commonly prescribed to Alzheimer's patients may significantly increase their risk of developing pneumonia.
April 10, 2017
Read More


Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer's disease
Mouse nicotinamide riboside study shows potential for human research.
February 6, 2018
Read More


Computer game may improve symptoms of mild cognitive impairment
Scientists have designed a brain training app that might boost episodic memory in people living with amnestic mild cognitive impairment - a potential precursor to dementia.
July 3, 2017
Read More


Computer-designed antibodies target toxins associated with Alzheimer's disease
The researchers used computer-based methods to develop antibodies -- the star players of the body's natural defence system -- to target the deposits of misfolded proteins which are a hallmark of Alzheimer's disease. Early tests of the antibodies in test tubes and in nematode worms showed an almost complete elimination of these pathogens.
June 23, 2017
Read More


Computerized speed of processing training results in decreased risk of dementia
Computerized brain-training is now the first intervention of any kind to reduce the risk of dementia among older adults. The breakthrough results from a randomized controlled trial were just published in the journal Alzheimer's & Dementia: Translational Research & Clinical Interventions.
November 16, 2017
Read More


Concussions Drive Dementia Risk Decades Later
A serious head injury may increase the risk for dementia even decades later, a new, large study suggests.
January 30, 2018
Read More


Cognitive tests can detect early Alzheimer's in people without symptoms, study suggests
Long before symptoms of Alzheimer's disease become apparent to patients and their families, biological changes are occurring within the brain. Amyloid plaques, which are clusters of protein fragments, along with tangles of protein known as tau, form in the brain and grow in number, eventually getting in the way of the brain's ability to function.
May 31, 2017
Read More


Contrary to decades of hype, curcumin alone is unlikely to boost health
Curcumin, a compound in turmeric, continues to be hailed as a natural treatment for a wide range of health conditions, including cancer and Alzheimer's disease. But a new review of the scientific literature on curcumin has found it's probably not all it's ground up to be. the report instead cites evidence that, contrary to numerous reports, the compound has limited -- if any -- therapeutic benefit.
January 11, 2017
Read More


Couch potatoes face same chance of dementia as those with genetic risk factors: Research
Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.
January 10, 2017
Read More


Could Alzheimer's be prevented with a vaccine?
Scientists have devised a vaccine that has shown promise in the treatment of psoriasis and cat allergies, as well as in the prevention of Alzheimer's disease.
October 24, 2017
Read More


Could an epilepsy drug help to slow Alzheimer's?
A drug currently used for the treatment of epilepsy may help to slow the progression of Alzheimer's disease, suggest the results of a new study.
June 26, 2017
Read More


Could blueberry vinegar tackle memory loss?
Scientists might have discovered a potential new treatment for dementia, in the form of blueberry vinegar. In the recent study, researchers show how the fermented product improved short-term memory in mice with amnesia.
December 20, 2017
Read More


Could inflammation in midlife predict dementia?
Newly published research concludes that inflammation in our 40s and 50s might be linked with increased brain shrinkage decades later. The ties between inflammation and dementia grow stronger.
November 2, 2017
Read More


Could lithium help to prevent dementia?
Lithium is a medication approved for the treatment of bipolar disorder, but a new study suggests that its therapeutic benefits may not stop there. Researchers have uncovered a link between lithium in drinking water and reduced risk of dementia.
August 23, 2017
Read More


Could lupus raise dementia risk?
People living with lupus may be at significantly greater risk of developing dementia than those without the autoimmune disease, a new study suggests.
November 9, 2017
Read More


Could olfactory loss point to Alzheimer's disease?
Odor identification tests may help scientists track the evolution of the disease in persons at risk
August 16, 2017
Read More


Could our blood reveal our future dementia risk?
After analyzing data from eight large studies, researchers have identified certain molecules in the blood that might serve as early biomarkers for the risk of developing dementia and Alzheimer's disease.
March 8, 2018
Read More


Could this hormone rejuvenate memory?
A new study published in The Journal of Experimental Medicine suggests that increased levels of a bone-produced hormone may prevent cognitive decline in older adults.
September 1, 2017
Read More


Could this protein hold the key to memory?
Researchers have identified a protein that plays a crucial role in whether we keep or discard memories. In the future, we might be able to use this knowledge to develop better drugs for memory loss, they say.
February 2, 2018
Read More


CRISPR helps find new genetic suspects behind ALS/FTD
Study provides roadmap for using CRISPR to investigate neurological disorders.
March 12, 2018
Read More


CRISPR helps find new genetic suspects behind ALS/FTD
Study provides roadmap for using CRISPR to investigate neurological disorders
March 12, 2018
Read More


Misc. - D

Deep brain stimulation studies in Alzheimer's disease pose ethical challenges
Researchers propose guidelines to better protect patients in DBS clinical trials
January 24, 2017
Read More


Delayed anticoagulation treatment for atrial fibrillation patients increases dementia risk, study finds
A new study has found that dementia rates increase when anticoagulation treatment is delayed for patients with atrial fibrillation, the most common heart arrhythmia in the world that affects more than 2.7 million American adults.
May 12, 2017
Read More


Delayed word processing could indicate MCI patients' likelihood of developing Alzheimer's
A delayed neurological response to processing the written word could be an indicator that a patient with mild memory problems is at an increased risk of developing Alzheimer's disease, research led by the University of Birmingham has discovered.
October 20, 2017
Read More


Delayed word processing could predict patients' potential to develop Alzheimer's disease
A delayed neurological response to processing the written word could be an indicator that a patient with mild memory problems is at an increased risk of developing Alzheimer's disease, research has discovered.
October 20, 2017
Read More


Delaying blood thinning treatment may raise dementia risk
Atrial fibrillation is a common form of heart abnormality, and patients who have it are often prescribed anticoagulants, or blood thinners. new research suggests that dementia rates increase in patients with atrial fibrillation whose anticoagulation treatment is delayed.
May 12, 2017
Read More


Dementia breakthrough? Brain-training game 'significantly reduces risk'
A recent study has been hailed as a "breakthrough" in dementia prevention, after finding that a brain-training exercise can lower the risk of the condition by more than a quarter.
November 16, 2017
Read More


Dementia Care a Huge Financial Hit for Families
Annual costs may top $320,000, study estimates
August 22, 2017
Read More


Dementia care improved by just one hour of social interaction each week
Increasing the amount of social interaction for people with dementia living in care homes to just one hour a week improves quality of life when combined with personalized care
February 6, 2018
Read More


Dementia-related brain changes observed before memory or thinking problems are noticeable
Scientists discover a potential predictor for early dementia that could inform the development of drug and therapeutic interventions to treat or slow down the disease.
May 12, 2017
Read More


Dementia: BACE inhibitor improves brain function
BACE inhibitor successfully tested in Alzheimer's animal model
July 28, 2017
Read More


Dementia: Study helps to unravel the cause of brain cell death
Dementia arises as a result of brain cell death, which may lead to a decline in learning, memory, and other cognitive functions, but precisely what triggers this process has been unclear. Now, a new study helps to shed some light.
October 9, 2017
Read More


Dementia: Unprecedented detail of brain damage revealed
Using extremely powerful cutting-edge technology, a new study shows in great detail how dementia with Lewy bodies affects synapses, the important connections between neurons.
November 22, 2017
Read More


Diabetes drug 'significantly reverses memory loss' in mice with Alzheimer's
A drug developed for diabetes could be used to treat Alzheimer's after scientists found it
January 1, 2018
Read More


Different genres of video games may affect cognitive training
Video games are quickly becoming a hot topic in cognitive training. Many see them as a potential tool to help patients improve their performance and memory, yet little is known about how different types of video games may affect white matter in the brain and cognition. In a new study in Restorative Neurology and Neuroscience investigators analyzed learning on two different types of video games--action and strategy--to determine if they were functionally different. They found that cognitive performance and white matter connectivity in the brain predicted how best we can learn to play the two types of games.
October 3, 2017
Read More


Discovery lights path for Alzheimer's research
Researchers identify binding site on amyloid beta peptide, learn to modify its structure
October 25, 2017
Read More


Discovery reveals way to stop inflammation in Alzheimer's, arthritis, more
Doctors could target electrical switch in immune system to battle many conditions, including deadly sepsis
February 26, 2018
Read More


Discovery sheds new light on pathology of Alzheimer's disease
Study offers new insights into how brain and rest of body communicate
February 6, 2018
Read More


Disrupted fat breakdown in the brain makes mice dumb
A new study opens a new perspective with regard to the development of dementia. The scientists blocked the breakdown of a certain fat molecule in the mouse brain. As a result the animals exhibited learning and memory problems. Also the quantity of Alzheimer-specific proteins in their brains increased significantly. The researchers now have a clue as to why the mice become dumb.
May 19, 2017
Read More


Disruption of 'slow waves' can lead to cognitive decline similar to Alzheimer's in mice
While unconscious during deep sleep, millions of neurons' activity travels across the cerebral cortex. This phenomenon, known as slow waves, is related to the consolidation of memory. The European project called SloW Dyn, led by Spanish scientists, has now revealed anomalies in this activity in mice displaying a decline similar to Alzheimer's.
September 5, 2017
Read More


Distorted memories play role in preserving knowledge for dementia patients, researchers say
Some memories containing inaccurate information can be beneficial to dementia sufferers because it enables them to retain key information researchers say.
March 6, 2018
Read More


DNA vaccine protects against toxic proteins linked to Alzheimer's
A new DNA vaccine, when delivered to the skin, prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer's disease -- without triggering severe brain swelling that earlier antibody treatments caused in some patients.
May 23, 2017
Read More


Does blood flow from the heart affect memory?
New research based on a large longitudinal study has revealed that reduced blood flow from the heart in old age also leads to poorer circulation in the temporal lobes of the brain, which constitute our memory "hub."
November 9, 2017
Read More


Dolls May Comfort People With Alzheimer's
Toy dolls can bring children comfort. And they may provide a similar perk later in life for people with dementia.
March 27, 2018
Read More


Dozens of Potential Alzheimer's Meds in the Pipeline
Last new drug for the memory-robbing disease was introduced in the United States in 2003
July 18, 2017
Read More


Dreaming may keep dementia at bay
According to new research, the rapid eye movement stage of sleep - which is when most of our dreaming occurs - may raise the risk of dementia if this phase is insufficiently entered.
August 23, 2017
Read More


Drug candidate stabilizes essential transport mechanism in nerve cells
NAP blocks formation of 'tangles' that contribute to Alzheimer's disease
January 31, 2017
Read More


Drug compound halts Alzheimer's-related damage in mice
Appears to reverse some neurological harm
January 25, 2017
Read More


Drugs already in medicine cabinets may fight dementia, early data suggests
In mouse and cell studies, drugs shut down damaging stress response, protected brain.
April 25, 2017
Read More


Dysfunctional microglia cells contribute to loss of synapses in Alzheimer's disease
Similar to other neurodegenerative disorders, Alzheimer's is a disease in which the cognitive abilities of afflicted persons continuously worsen. The reason is the increasing loss of synapses, the contact points of the neurons, in the brain. In the case of Alzheimer's, certain protein fragments, the β-amyloid peptides, are suspected of causing the death of neurons. These protein fragments clump together and form the disease's characteristic plaques.
June 30, 2017
Read More


Misc. - E

E-Scape Bio announces extension of funding to develop novel drug for Alzheimer's disease
E-Scape Bio announced an extension of its Series A funding to a total of $63 million. Created as a spin-off from research conducted at the Gladstone Institutes, E-Scape Bio is a biopharmaceutical company with a mission to develop new therapies to treat neurodegenerative disorders such as Alzheimer's disease.
July 12, 2017
Read More


Early life physical activity may prevent cognitive decline
Could early life physical exercise protect against age-related cognitive decline by creating a so-called cognitive reserve? A study in rodents investigates.
August 15, 2017
Read More


Educational materials released by Eisai for understanding dementia
Eisai Co., Ltd. announced that it has created educational materials for understanding dementia and thinking about what one can do for elementary and secondary school students, and has commenced marketing these materials primarily to local governments, educational institutions as well as medical and nursing care professionals from today.
December 18, 2017
Read More


Elderly people with MCI have weakened ability to memorize human faces, research reveals
A Japanese research group has revealed that elderly people with mild cognitive impairment (MCI) have a particularly weakened ability to memorize human faces in the short term when compared to healthy elderly people. MCI patients also had a different gaze behavior when trying to memorize a face. This research may lead to the early detection of dementia.
November 22, 2017
Read More


Elderly who have trouble identifying odors face risk of dementia
Smell loss predicts cognitive decline in healthy older people
September 29, 2017
Read More


Electrically Stimulating a Specific Brain Region using Ultrafine Wires Enhances Memory
Neuroscientists at UCLA have found that electrically stimulating a specific area of the brain using ultrafine wires enhances memory in epilepsy patients. If the technique can enhance memory in other patients, it might help with conditions such as Alzheimer's disease.
October 26, 2017
Read More


Emory scientists show how same enzyme spurs Alzheimer's and Parkinson's disease
Alzheimer's disease and Parkinson's disease are not the same. They affect different regions of the brain and have distinct genetic and environmental risk factors.
July 4, 2017
Read More


Enhanced lifestyle counselling could protect against Alzheimer's disease, finds new study
Enhanced lifestyle counselling could prevent cognitive decline in people who are genetically predisposed to develop Alzheimer's disease, finds new study.
January 26, 2018
Read More


'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's disease
Researchers profiled the epigenomic landscape of Alzheimer's brains, specifically in one of the regions affected early in AD, the lateral temporal lobe. They compared these to both younger and elderly cognitively normal control subjects. The team described the genome-wide enrichment of a chemical modification of histone proteins that regulates the compaction of chromosomes in the nucleus.
March 5, 2018
Read More


Evidence of Alzheimer's in patients with Lewy body disease tracks with course of dementia
Patients who had a diagnosis of Parkinson's disease with dementia or dementia with Lewy bodies and had higher levels of Alzheimer's disease pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases during their lives, compared to those whose brains had less AD pathology.
January 5, 2017
Read More


Evolution Not Over for Humans
Study finds natural selection still happening, with gene variants linked to Alzheimer's, smoking fading
September 5, 2017
Read More


Exercise right after learning improves memory in women
Whether you are cramming for an exam or simply want to give your memory a boost, doing some physical exercise straight after a learning session may be of great help - if you are a woman, that is.
August 29, 2017
Read More


Expert provides insights into risks of dementia and Alzheimer's disease
While often used interchangeably, dementia and Alzheimer's disease are not the same. Dementia is a general term for a decline in mental ability severe enough to interfere with daily life. Alzheimer's disease is a specific type of dementia that causes memory loss and impairment of other important mental functions. An expert from the Texas Aamp;&M School of Public Health describes how these conditions can impact the lives of both patients and those around them, and provides insights into ways of minimizing risks.
July 4, 2017
Read More


Experts explore ways to improve safety of care for nursing home residents with dementia
By 2050, the number of people 65 and older with dementia in the United States is expected to nearly triple -- from 5 million to more than 13 million -- increasing the numbers in assisted living and nursing homes.
August 16, 2017
Read More


Experts: Getting Active Could Help Boost Memory
Physical activity is good for the body and the brain, but what about people with thinking and memory difficulties?
December 28, 2017
Read More


Extra-virgin olive oil preserves memory, protects brain against Alzheimer's
The Mediterranean diet is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers have identified a specific ingredient that protects against cognitive decline: extra-virgin olive oil. In a new study, the researchers show that consumption of extra-virgin olive oil protects memory and learning ability and reduces the formation of amyloid-beta plaques and neurofibrillary tangles in the brain -- classic markers of Alzheimer's disease.
June 21, 2017
Read More


Extra-virgin olive oil may prevent Alzheimer's
New research suggests that extra-virgin olive oil - a key component of the Mediterranean diet - may protect the brain from Alzheimer's disease symptoms. Mouse experiments revealed changes in both cognitive performance and the appearance of nerve cells.
June 21, 2017
Read More


Misc. - F

Feeling sleepy during the day could predict Alzheimer's disease finds study
In a new study, researchers have shown that excessive sleepiness during the day time among elderly who had normal mental acuity and cognitive powers is associated with the buildup of amyloid plaques in the brain that is typical of Alzheimer's disease.
March 13, 2018
Read More


Feinstein researcher awarded NIH grant to better understand genetic causes of Alzheimer's disease
Feinstein Institute for Medical Research Assistant Professor Yun Freudenberg-Hua, MD, has been awarded a five-year, $600,000 grant from the National Institutes of Health's (NIH) National Institute on Aging to identify genetic risk factors for Alzheimer's disease. A better understanding of the genetic causes of the disease will help develop possible treatments for the estimated 5.5 million Americans currently suffering from the condition along with intervention programs for those at risk.
August 11, 2017
Read More


'Filter' hones GWAS results to help researchers avoid dead ends
A new strategy gives scientists a biologically informed way to select genes to study
March 5, 2018
Read More


First Alzheimer's Patient Treated with Focused Ultrasound to Open Blood-Brain Barrier
The blood-brain barrier prevents almost all potentially therapeutic drugs from passing into the brain. this has been a major roadblock for clinical neurology, but we may have a solution, perhaps a partial one, in the form of focused ultrasound. the first Alzheimer's patient has just been treated using ultrasound to open up the blood-brain barrier in his brain. Though no drugs have been administered, the researchers are evaluating the safety and effectiveness of the technique on such patients. Previously, only chemo agents have been delivered into the brain by opening the blood-brain barrier using ultrasound, but if this study goes well the next step will involve drug delivery.
May 5, 2017
Read More


Five ways to boost your memory
Anyone can improve their memory, unless they are experiencing memory loss as part of a medical condition. Whether you want to ace your science test, enter the World Memory Championships, or preserve and enhance your memory as you age, we have some memory-boosting tips that may help.
October 25, 2017
Read More


Flies the key to studying the causes of dementia
Discovery relating to brain proteins could lead to new effective therapies for dementia and other neurodegenerative diseases
May 19, 2017
Read More


For white middle class, moderate drinking is linked to cognitive health in old age
Older adults who consume alcohol moderately on a regular basis are more likely to live to the age of 85 without dementia or other cognitive impairments than non-drinkers, according to a new study.
August 1, 2017
Read More


From the omelette to the egg: Reversing protein aggregations
Some protein aggregations are reversible and beneficial, Tel Aviv University researchers say.
December 18, 2017
Read More


Misc. - G

Gene therapy prevents age-related learning and memory problems in mice
Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona (INc-UAB) and the Vall d'Hebron Research Institute (VHIR) are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age-related learning and memory problems in mice.
October 31, 2017
Read More


Gene Discovery May Help Fight Alzheimer's
Alzheimer's disease has long remained a deadly mystery.
December 5, 2017
Read More


Gene variant protecting against Alzheimer's disease decreases plasma beta-amyloid levels
The APP gene variant protecting against Alzheimer's disease significantly decreases plasma beta-amyloid levels in a population cohort. This is a very significant discovery, as many on-going drug trials in the field of Alzheimer's disease focus on decreasing beta-amyloid levels in the brain tissue.
June 19, 2017
Read More


Gene variant that protects against Alzheimer's disease identified
Study reveals specific reason why people who 'should' get the disease remain healthy
November 29, 2017
Read More


Glucose deprivation in the brain triggers onset of cognitive decline, research shows
One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment -- before symptoms of memory problems begin to surface. Whether it is a cause or consequence of neurological dysfunction has been unclear, but new research at the Lewis Katz School of Medicine at Temple University now shows unequivocally that glucose deprivation in the brain triggers the onset of cognitive decline, memory impairment in particular.
January 31, 2017
Read More


Misc. - H

Half of all dementias start with damaged 'gatekeeper cells'
Once the cells are compromised, the brain's protective fort becomes leaky and allows blood toxins to trespass into the brain, damaging critical connections between brain areas, researchers say.
February 5, 2018
Read More


Head injuries may lead to early Alzheimer's
Contact sports that can result in concussions, such as football, have given rise to worries that these head injuries may harm brain health later in life. A new study now investigates these claims in relation to the development of Alzheimer's disease.
March 6, 2018
Read More


Healthy mitochondria could stop Alzheimer's
Using a bioinformatics and experimental approach, scientists have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease.
December 6, 2017
Read More


'Heart Harm' In Middle Age Can Lead To Dementia
Of greatest importance are diabetes, blood pressure and smoking, researchers say
August 7, 2017
Read More


Heart-healthy middle age tied to lower risk of dementia
The chance of developing dementia is tied to a number of factors, including some that can also influence cardiovascular health, such as diabetes, high blood pressure, and smoking. A new study shows that having these risk factors in middle age might increase the likelihood of having dementia later in life.
August 7, 2017
Read More


Heartburn Meds Don't Raise Alzheimer's Risk: Study
New research debunks other studies suggesting that medications used to treat ulcers, reflux cause mental decline
June 28, 2017
Read More


Heavy Drinkers Put Themselves at Risk for Dementia
The ills that are linked to heavy drinking now include dementia, a new study warns.
February 22, 2018
Read More


High Blood Pressure May not be all Bad in Elderly
Developing it after 80 might help prevent mental decline, research suggests
January 17, 2017
Read More


High cholesterol in late life may mean better brain health
A study of older people has found that having a total cholesterol level higher than it was in midlife is tied to a lower risk of marked cognitive decline in those aged 85--94. This was in stark contrast to the results found for the age group that was 10 years younger.
March 5, 2018
Read More


High cholesterol intake and eggs do not increase risk of memory disorders
A relatively high intake of dietary cholesterol, or eating one egg every day, are not associated with an elevated risk of dementia or Alzheimer's disease. Furthermore, no association was found in persons carrying the APOE4 gene variant that affects cholesterol metabolism and increases the risk of memory disorders, report researchers at conclusion of a new study.
January 9, 2017
Read More


High definition eye scan could reveal crucial warning signs of Alzheimer's disease
Cedars-Sinai neuroscience investigators have found that Alzheimer's disease affects the retina -- the back of the eye -- similarly to the way it affects the brain. The study also revealed that an investigational, noninvasive eye scan could detect the key signs of Alzheimer's disease years before patients experience symptoms.
August 17, 2017
Read More


High fitness may slash dementia risk, study says
Being physically fit is known to bring a range of health benefits -- from staving off metabolic diseases to offering protection against heart disease. A new study may now have uncovered an additional advantage for women: a highly decreased risk of dementia.
March 15, 2018
Read More


High intensity exercise improves memory, study finds
The health advantages of high-intensity exercise are widely known but new research from McMaster University points to another major benefit: better memory.
November 22, 2017
Read More


High protein diet reduces risk of Alzheimer's disease, research finds
A diet high in protein-rich foods such as meat and legumes reduces the risk of developing Alzheimer's disease, new research from Edith Cowan University has found.
February 23, 2018
Read More


Higher brain glucose levels may mean more severe Alzheimer's
NIH study shows connections between glucose metabolism, Alzheimer's pathology, symptoms.
November 6, 2017
Read More


Higher dementia risk associated with birth in high stroke mortality states
Is being born in states with high stroke mortality associated with dementia risk in a group of individuals who eventually all lived outside those states? A new article suggests it might be.
July 31, 2017
Read More


History of traumatic brain injury not related to cognitive decline, study shows
Although much research has examined traumatic brain injury (TBI) as a possible risk factor for later life dementia from neurodegenerative diseases such as Alzheimer's disease (AD), little is known regarding how TBI influences the rate of age-related cognitive change. A new study now shows that history of TBI (with loss of consciousness) does not appear to affect the rate of cognitive change over time for participants with normal cognition or even those with AD dementia.
July 4, 2017
Read More


Hold the salt: gut reaction may impair the brains of mice
NIH-funded study suggests impaired blood flow and dementia can result from a high-salt diet.
January 18, 2018
Read More


Hospital patients with dementia and other causes of confusion 'have worse outcomes'
Hospital patients with dementia and other causes of confusion have longer stays and worse treatment outcomes than people without the condition, new research has found.
August 1, 2017
Read More


How a green tea compound could prevent Alzheimer's
Studies have tied green tea to a reduced risk of Alzheimer's, but the mechanisms underlying this link have been unclear. Now, a new study reveals how a compound in the popular beverage disrupts the formation of toxic plaques that contribute to the disease.
October 13, 2017
Read More


How an eye test could detect Alzheimer's
What if Alzheimer's could be diagnosed through a routine visit to the opticians? Researchers may have brought us a step closer to such a feat, after developing an optical imaging system that can detect a hallmark of the disease.
August 23, 2017
Read More


How brain cells die in Alzheimer's and FTD
Epigenetic regulator LSD1 tangled up; brain cells go haywire without it
October 9, 2017
Read More


How can PTSD trigger Alzheimer's disease? Study sheds light
More and more evidence is suggesting that developing post-traumatic stress disorder early in life can raise the risk of dementia in old age. New research finds a molecular link between the two conditions, which paves the way for new therapies.
August 4, 2017
Read More


How daytime sleepiness may raise Alzheimer's risk
Alzheimer's -- a progressive, neurodegenerative condition -- is characterized by memory loss and cognitive impairments. Early warning signs include confusion regarding habitual tasks and severe changes to behavior. But are there any less intuitive signals to watch out for?
March 12, 2018
Read More


How do adult brain circuits regulate new neuron production?
Researchers identified a brain circuit that controls neuron development in the adult brain. It runs from near the front of the brain back to the hippocampus, a learning- and memory-related structure.
November 2, 2017
Read More


How does exercise preserve the aging brain?
Further evidence that doing aerobic exercise can preserve brain health and function -- and thereby reduce the risk of dementia -- is revealed in a study of older individuals with slight but noticeable declines in memory and thinking.
February 16, 2018
Read More


How fighting ageism may lower dementia risk
New research suggests that the beliefs we hold about old age may influence our risk of developing dementia, even if we're genetically predisposed to it.
February 8, 2018
Read More


How One Drug Could Affect Pain, Memory and Nicotine Addiction
Researchers are working to develop drugs to enhance the function of these receptors in the brain, which could have three very different applications: easing pain, slowing the cognitive decline associated with Alzheimer's and making it easier for people to stop smoking.
May 5, 2017
Read More


How One Town Hopes to Cure Alzheimer's
Judy Culbertson gets lost sometimes. She might be on her way home from the grocery store or some other place she's been dozens of times, when she suddenly finds herself on a street she doesn't recognize.
May 19, 2017
Read More


How SORLA protects against Alzheimer's disease
Study findings could lead to new therapeutic approaches to slow brain degeneration
November 7, 2017
Read More


How to Keep Drivers With Dementia Off the Road
Don't count on physicians to keep drivers with dementia off the roads, a new study cautions.
February 2, 2018
Read More


Human enzyme can reduce neurotoxic amyloids in a mouse model of dementia
A naturally occurring human enzyme -called cyclophilin 40 or CyP40- can unravel protein aggregates that contribute to both Alzheimer's disease and Parkinson's disease, according to a study. The finding may point toward a new therapeutic strategy for these diseases.
June 27, 2017
Read More


Human enzyme may be key to unraveling Alzheimer's disease
Protein aggregates are the hallmark of a number of neurodegenerative diseases. New research, published in the journal PLOS Biology, examines a human enzyme that unravels these disruptive plaques.
June 28, 2017
Read More


Hyperbaric oxygen therapy may alleviate symptoms of Alzheimer's Disease
Treatment has potential to correct behavioral and physical deficits associated with the disease
December 5, 2017
Read More


Misc. - I

If you want to avoid dementia, get hitched
Is it really possible that marriage can improve your chances of side-stepping dementia? According to the latest review of the evidence, married folk have a much lower risk of developing dementia than lifelong singletons.
November 29, 2017
Read More


In Alzheimer's, excess tau protein damages brain's GPS
Finding may explain why many Alzheimer's disease patients wander
January 19, 2017
Read More


Inflammation drives progression of Alzheimer's
A molecular complex of the immune system promotes aberrant aggregation of proteins
December 20, 2017
Read More


Innovative microscope poised to propel optogenetics studies
New microscope has more than 100 times larger field of view for studying brain activity
November 29, 2017
Read More


Interrupted sleep could be an early sign of Alzheimer's disease, finds new study
In a recent study, scientists at Washington University School of Medicine observed a link between circadian rhythm disruptions (the body clock that determines our sleep/wake cycle) and the risk of an individual developing Alzheimer's disease.
January 30, 2018
Read More


Interventions to prevent cognitive decline, dementia
Evidence supporting three interventions that might slow cognitive decline and the onset of dementia is encouraging but insufficient to justify a public health campaign focused on their adoption
June 22, 2017
Read More


Is Dementia Declining Among Older Americans?
Rates have fallen among those 70 and older; gains against heart disease might explain trend
September 5, 2017
Read More


Is the bold claim that a nutrient drink can slow Alzheimer's true?
It's a bold claim: the brain regrows vital neuronal connections after a person in the early stages of Alzheimer's disease sips a daily nutrient drink. Cognitive decline slows down. But that's not what the latest study found.
November 2, 2017
Read More


Isolating anti-Alzheimer's compounds in plants
Scientists develop new technique to isolate active therapeutic compounds for Alzheimer's disease from plants
June 19, 2017
Read More


Misc. - J

Just one night of poor sleep can boost Alzheimer's proteins
Amyloid-beta levels rose in healthy adults with interrupted slow-wave Zs
July 10, 2017
Read More


Misc. - K

Kale nutrient may yield significant cognitive benefits
Researchers have found that lutein, a nutrient and organic pigment found in kale, spinach, avocados, and eggs, may be effective in rejuvenating cognitive functions.
July 28, 2017
Read More


Key synaptic proteins could be targets for early interventions in patients with dementias
One of the most intriguing properties of the brain is its means to undergo synaptic plasticity which represents the basis for learning and memory, abilities that severely decline in the case of a dementia. New research from Karolinska Institutet, published in the scientific journal Brain, suggests that particular proteins important in the communication between neurons could be targets for early interventions in patients with different types of dementias.
January 9, 2018
Read More


Misc. - L

Large-scale production of living brain cells enables entirely new research
Important pieces of the puzzle to understand what drives diseases such as Alzheimer's and Parkinson's are still missing today. One crucial obstacle for researchers is that it is impossible to examine a living brain cell in someone who is affected by the disease. With the help of a new method for cell conversion, researchers have found a way to produce diseased, aging brain cells on a large scale in a cell culture dish.
June 26, 2017
Read More


Large-scale production of living brain cells enables entirely new research
Important pieces of the puzzle to understand what drives diseases such as Alzheimer's and Parkinson's are still missing today. One crucial obstacle for researchers is that it is impossible to examine a living brain cell in someone who is affected by the disease.
June 26, 2017
Read More or Watch Video


Largest study of its kind finds alcohol use biggest risk factor for dementia
Alcohol use disorders are the most important preventable risk factors for the onset of all types of dementia, especially early-onset dementia. This according to a nationwide observational study of over one million adults diagnosed with dementia in France.
February 20, 2018
Read More


Leaving 'Stroke Belt' Doesn't Lower Dementia Risk
Study found odds for mental decline still higher for those born in certain southeastern U.S. states
July 31, 2017
Read More


Leisure activities lower blood pressure in Alzheimer's caregivers
Going for a walk outside, reading, listening to music -- these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer's disease, suggests a study.
June 23, 2017
Read More


Life-extending protein could treat Alzheimer's and Parkinson's
New research has shown that a naturally occurring protein can improve cognition in mice with Alzheimer's and Parkinson's disease-like characteristics. The findings open up a new therapeutic avenue for treating these neurodegenerative illnesses.
August 8, 2017
Read More


Lifestyle changes prevent cognitive decline even in genetically susceptible individuals
Enhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, according to a new study.
January 25, 2018
Read More


Link between vascular disease and Alzheimer's strengthened
The more risk factors for vascular disease one has in middle age, the higher the risk may be of developing Alzheimer's disease in later life.
April 11, 2017
Read More


Lithium in drinking water can slow Alzheimer's disease mortality rates, study finds
Rates of diabetes and obesity, which are important risk factors for Alzheimer's disease, also decrease if there is a particular amount of lithium in the water, says the study, published recently in the Journal of Alzheimer's Disease.
December 6, 2017
Read More


Losing sense of smell linked to dementia
Scientists have found that losing the sense of smell is an early sign that a person is at risk of development of dementia later in life. The study entitled "Olfactory Dysfunction Predicts Subsequent Dementia in Older US Adults," was published in the latest issue of the Journal of the American Geriatrics Society.
October 2, 2017
Read More


Loving Kids May Help Lower Seniors' Dementia Risk
But negative relationships with children, spouse increased chances, study finds
May 2, 2017
Read More


Low levels of alcohol helps the brain clear away toxins, study shows
While a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well. The new study, which appears in the journal Scientific Reports, shows that low levels of alcohol consumption tamp down inflammation and helps the brain clear away toxins, including those associated with Alzheimer's disease.
February 2, 2018
Read More


Low levels of alcohol good for the brain, study shows
While a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well. The new study shows that low levels of alcohol consumption tamp down inflammation and helps the brain clear away toxins, including those associated with Alzheimer's disease.
February 2, 2018
Read More


Lumosity Brain-Training Didn't Boost Thinking Skills: Study
Young adults who took the program performed no better than those who played video games
July 10, 2017
Read More


Misc. - M

Maintaining sufficient vitamin D levels may help to prevent rheumatoid arthritis
Maintaining sufficient vitamin D levels may help to prevent the onset of inflammatory diseases like rheumatoid arthritis, research has discovered.
November 21, 2017
Read More


Mathematical Analysis of Brush Strokes Spots Artists with Dementia
Artists often develop new creative techniques late in life, often at the same time as they begin suffering from dementia. some scientists suspect that it is the dementia itself that fosters ways of expression that haven't been tried by the artists before. at the University of Liverpool a team of researchers wanted to examine this connection further by performing fractal analysis of paintings of famous artists. Specifically, they were looking for evidence of cognitive decline within the brush strokes of art works completed before and after the onset of artists' dementia.
January 3, 2017
Read More


Memocate offers solutions for interaction problems that arise from memory disorders
A startup based on University of Helsinki research offers solutions for the interaction problems that arise from memory disorders.
July 4, 2017
Read More


Menopause may trigger Alzheimer's disease
A new study highlights the metabolic changes that occur in the brains of menopausal and perimenopausal women, suggesting that a loss of estrogen could make these women vulnerable to developing Alzheimer's disease.
October 11, 2017
Read More


Midlife cardiovascular risk factors may increase chances of dementia
Study supports link between cognition and vascular health
August 7, 2017
Read More


Midlife cardiovascular risk factors may increase chances of dementia
NIH funded study supports link between cognition and vascular health.
August 7, 2017
Read More


Mild cognitive impairment, Alzheimer's diagnoses trigger lower self-ratings of quality of life
A patient's awareness of a diagnosis of cognitive impairment may diminish their self-assessment of quality of life, suggests new research.
August 3, 2017
Read More


MIND diet may slow cognitive decline in stroke survivors
A diet created by researchers may help substantially slow cognitive decline in stroke survivors, according to preliminary research. The finding are significant because stroke survivors are twice as likely to develop dementia compared to the general population.
January 26, 2018
Read More


Moderate drinking correlates with cognitive health, longevity
The results of a new study point to a correlation between regular but moderate drinking in older adults, and a reduced risk of cognitive impairments. This research was based on a cohort study of middle-class adults in the United States.
August 3, 2017
Read More


Molecular basis for memory and learning: Brain development and plasticity share similar signalling pathways
Learning and memory are two important functions of the brain that are based on the brain's plasticity. Scientists now report on how a trio of key molecules directs these processes. Their findings provide new leads for the therapy of Alzheimer's disease.
October 9, 2017
Read More


Molecular link between post-traumatic stress disorder and Alzheimer's disease
There is increasing evidence that post-traumatic stress disorder (PTSD) increases the risk of developing dementia later in life. Researchers now shed light on the molecular mechanism that links the two disorders.
August 2, 2017
Read More


More brain activity is not always better when it comes to memory, attention
Potential new ways of understanding the cause of cognitive impairments, such as problems with memory and attention, in brain disorders including schizophrenia and Alzheimer's are under the spotlight in a new research review.
June 15, 2017
Read More


Mouse model points to potential new treatment for Alzheimer's disease
Treatment with an inhibitor of 12/15-lipoxygenase, an enzyme elevated in patients with Alzheimer's disease (AD), reverses cognitive decline and neuropathology in an AD mouse model, reports a new study. the effects were observed after the AD-like phenotype was already established in the mice, which is promising for its potential therapeutic use, as neuropathology tends to develop many years before the appearance of AD symptoms in patients.
January 5, 2017
Read More


Misc. - N

Nanowired Drugs for Treating Alzheimer's and Parkinson's Diseases
Millions of Americans suffer from neurodegenerative diseases such as Parkinson's and Alzheimer's. Researchers have identified new treatments, such as cerebrolysin, which are promising, but present clinical approaches are ineffective as critical concentrations of the drug dissipate within the body prior to reaching the central nervous system and brain.
November 16, 2017
Read More


NAS report: Promising but inconclusive evidence on interventions to prevent cognitive decline, dementia
Suggests NIH, others carefully cue public about potential benefits of cognitive training, blood pressure management, exercise.
June 22, 2017
Read More


Natural compound found in strawberries may help prevent age-related diseases
Salk scientists have found further evidence that a natural compound in strawberries reduces cognitive deficits and inflammation associated with aging in mice. The work, which appeared in the Journals of Gerontology Series A in June 2017, builds on the team's previous research into the antioxidant fisetin, finding it could help treat age-related mental decline and conditions like Alzheimer's or stroke.
July 11, 2017
Read More


Natural tooth repair method, using Alzheimer's drug, could revolutionize dental treatments
A new method of stimulating the renewal of living stem cells in tooth pulp using an Alzheimer's drug has been discovered by a team of researchers.
January 9, 2017
Read More


Navigation and spatial memory: New brain region identified to be involved
Navigation in mammals including humans and rodents depends on specialized neural networks that encode the animal's location and trajectory in the environment, serving essentially as a GPS, findings that led to the 2014 Nobel Prize in Medicine. Failure of these networks to function properly, as seen in Alzheimer's disease and other neurological conditions, results in severe disorientation and memory deficits.
August 16, 2017
Read More


Neurons' sugar coating is essential for long-term memories
How the brain is able to store memories over long periods of time has been a persistent mystery to neuroscientists. In a new study, researchers show that long-lived extracellular matrix molecules called perineuronal nets are essential for distant memories.
December 27, 2017
Read More


Neuroscientists say daily ibuprofen can prevent Alzheimer's disease
Neuroscientists have successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.
March 26, 2018
Read More


New antibodies target protein structures common to several neurological diseases
A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach.
August 29, 2017
Read More


New biology of Alzheimer's disease described by researchers
Findings may lead to new treatment options
November 20, 2017
Read More


New brain disease test for Parkinson's, dementia with Lewy bodies
Scientists have modified a test for early diagnosis of prion diseases with the goal of improving early diagnosis of Parkinson's disease and dementia with Lewy bodies. The group tested cerebral spinal fluid samples from people with Parkinson's disease; people with dementia with Lewy bodies; and controls, some of whom had Alzheimer's disease.
February 9, 2018
Read More


New data mining strategy spots those at high risk of Alzheimer's
Method could group similar Alzheimer's patients for more precise drug trials
July 28, 2017
Read More


New details on aged brain, Alzheimer's and dementia
Robust analysis of samples from 107 human brains highlights features of healthy and diseased aging
November 21, 2017
Read More


New device uses AI algorithm to monitor sleep with radio waves
More than 50 million Americans suffer from sleep disorders, and diseases including Parkinson's and Alzheimer's can also disrupt sleep. Diagnosing and monitoring these conditions usually requires attaching electrodes and a variety of other sensors to patients, which can further disrupt their sleep.
August 7, 2017
Read More


New discovery may allow doctors to treat inflammation in neurodegenerative diseases
A new discovery about the immune system may allow doctors to treat harmful inflammation that damages the brain in neurodegenerative diseases such as Alzheimer's. It might also let doctors save patients from the potentially deadly inflammation of sepsis, a full-body infection that kills a quarter-million Americans every year.
February 26, 2018
Read More


New easy-to-use tool can help determine Alzheimer's risk, similar to pediatric growth curves
A simple new tool that tracks cognitive performance in adults aims to help physicians identify people who may be on the path to Alzheimer's disease or another form of dementia.
December 4, 2017
Read More


New genetic variants associated with extreme old age
The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations. But a recently published study that combines four studies of extreme longevity, has identified new rare variants in chromosomes 4 and 7 associated with extreme survival and with reduced risks for cardiovascular and Alzheimer's disease.
April 25, 2017
Read More


New 'GPS' neuron discovered
A new type of neuron that might play a vital role in humans' ability to navigate their environments, report investigators. The discovery is an important step towards understanding how the brain codes navigation behavior at larger scales and could potentially open up new treatment strategies for people with impaired topographical orientation like Alzheimer's patients.
May 29, 2017
Read More


New imaging technique able to watch molecular dynamics of neurodegenerative diseases
Researchers have developed a fast and practical molecular-scale imaging technique that could let scientists view never-before-seen dynamics of biological processes involved in neurodegenerative diseases such as Alzheimer's disease and multiple sclerosis.
July 13, 2017
Read More


New intervention improves communication behaviors in couples affected by dementia
They do it with the best of intentions. "Do you remember our wedding day?" "Who is that person next to you in the picture?" For couples with decades of shared memories, a partner's decline in the ability to communicate is one of the most frightening and frustrating consequences of Alzheimer's disease and related dementias.
February 22, 2018
Read More


New mechanism detected in Alzheimer's disease
Rate of RNA decay could be a key to breakdown in communication between neurons
October 13, 2017
Read More


New mechanisms found of cell death in neurodegenerative disorders
New mechanisms of cell death have now been discovered, which may be involved in debilitating neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, report scientists.
November 22, 2017
Read More


New microscope optimized to perform studies using optogenetic techniques
A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication. The microscope is optimized to perform studies using optogenetic techniques, a relatively new technology that uses light to control and image neurons genetically modified with light-sensitive proteins.
November 29, 2017
Read More


New molecular discovery may help identify drug therapies to prevent dementia
Scientists pinpoint protein in brain pathway that enhances memory
January 10, 2017
Read More


New NIH consortium award to enhance clinical trials for Alzheimer's disease, related dementias
Effort streamlines study infrastructure to improve recruitment diversity, advance research.
December 11, 2017
Read More


New non-invasive biomarker detects Alzheimer's disease before occurrence of first symptoms
Absence of a prefrontal activation during sensory gating of simple tones detects the Alzheimer's disease (AD) before the occurrence of the first symptoms. Sanja Josef Golubic Ph.D., physicists at the Department of Physics, Faculty of Science, University of Zagreb, reveals the high potential, absolutely non-invasive biomarker of AD pathology in a new study published in the journal Human Brain Mapping. Josef Golubic found a discrete, individual biomarker of AD with "ideal" properties.
October 3, 2017
Read More


New partnership uses artificial intelligence methods to develop solutions for preventing early aging
Center for Healthy Aging at the University of Copenhagen today announced a research collaboration with a company specializing in artificial intelligence (AI) to develop solutions for preventing early aging. The aim of this partnership is to develop medicines to prevent and cure a broad range of diseases associated with aging such as Alzheimer's, Parkinson's and cardiovascular diseases.
August 1, 2017
Read More


New PET imaging agent could help guide treatments for people with neurological diseases
Researchers have developed a new imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis. The agent, which is used in positron emission tomography (PET) scans, targets receptors in nerve cells in the brain that are involved in learning and memory.
April 02, 2018
Read More


New player in Alzheimer's disease pathogenesis identified
Findings may provide new direction for discovery of therapeutics
November 14, 2017
Read More


New possibility of studying how Alzheimer's disease affects the brain at different ages
Alzheimer's disease can lead to several widely divergent symptoms and, so far, its various expressions have mainly been observed through the behavior and actions of patients. Researchers have now produced images showing the changes in the brain associated with these symptoms -- a development which increases knowledge and could facilitate future diagnostics and treatment.
August 31, 2017
Read More


New research shows where in the brain the earliest signs of Alzheimer's occur
For the first time, researchers have convincingly shown where in the brain the earliest signs of Alzheimer's occur. The discovery could potentially become significant to future Alzheimer's research while contributing to improved diagnostics.
November 1, 2017
Read More


New scientific yardstick released to help early detection of Alzheimer's disease
The European Commission's Joint Research Centre (JRC) released a new scientific yardstick, in the form of a certified reference material, to help early detection of Alzheimer's disease.
December 12, 2017
Read More


New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease
An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease. The drug works by stopping toxic ion flow in the brain that is known to trigger nerve cell death. Scientists envision that this drug could be used to treat Alzheimer's and other neurodegenerative diseases such as Parkinson's and ALS.
December 5, 2017
Read More


New study examines potential Alzheimer's disease prevention strategies
Alzheimer's disease (AD) is a type of dementia that causes problems with memory, thinking, and behavior. It affects more than 5 million Americans. The Alzheimer's Association estimates that some 16 million people will develop the disease by the year 2050 if an effective treatment is not discovered. Symptoms of AD usually develop slowly and worsen over time. They often become severe enough to interfere with daily tasks, and can eventually cause death.
August 9, 2017
Read More


New substance restores brain function in Alzheimer's animal model
The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments. A team at the Technical University of Munich (TUM) has recently demonstrated that one such BACE inhibitor reduces the amount of amyloid beta in the brain. By doing so, it can restore the normal function of nerve cells and significantly improve memory performance.
July 28, 2017
Read More


New technology aims to provide peace and positive stimulation to dementia patients
To alleviate boredom and increase engagement, elderly patients in long-term care facilities can engage with the Ambient Activity Technology device any time to view family photos, hear their favorite music, and play games.
June 28, 2017
Read More


New type of cell that clears waste from the brain discovered
Scientists have found a previously unknown type of cell that clears waste away from the brain. they suggest that their findings will increase our understanding of the brain's biology and of diseases such as dementia and stroke.
May 2, 2017
Read More


NIH scientists adapt new brain disease test for Parkinson's, dementia with Lewy bodies
National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson's disease and dementia with Lewy bodies. The group, led by NIH's National Institute of Allergy and Infectious Diseases (NIAID), tested 60 cerebral spinal fluid samples, including 12 from people with Parkinson's disease, 17 from people with dementia with Lewy bodies, and 31 controls, including 16 of whom had Alzheimer's disease.
February 9, 2018
Read More


NIH scientists modify new RT-QuIC assay to detect Parkinson's, dementia with Lewy bodies
National Institutes of Health scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the assay to offer the possibility of improving early diagnosis of Parkinson's disease and dementia with Lewy bodies. The group, led by NIH's National Institute of Allergy and Infectious Diseases (NIAID), tested 60 cerebral spinal fluid samples, including 12 from people with Parkinson's disease, 17 from people with dementia with Lewy bodies, and 31 controls, including 16 of whom had Alzheimer's disease
February 9, 2018
Read More


NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD
NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) caused by mutations in a gene called C9orf72.
March 13, 2018
Read More


Noninvasive retinal imaging may improve early detection of Alzheimer's disease
Alzheimer's disease (AD) represents the leading cause of dementia worldwide. Currently, challenges in making an early and definitive diagnosis of AD limit opportunities to intervene with disease-modifying therapies before substantial neurodegeneration occurs.
August 17, 2017
Read More


Not being aware of memory problems predicts onset of Alzheimer's disease
New research could provide clinicians with insights regarding clinical progression to dementia
February 15, 2018
Read More


Novel biomarkers for future dementia risk
Participants' blood samples were drawn years before their dementia diagnosis
March 6, 2018
Read More


Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer's disease
For decades, researches have been investigating the underlying foundations of Alzheimer's disease to provide clues for the design of a successful therapy. Breakthrough insights reveal the molecular basis of the hereditary form of Alzheimer's disease that strikes early in life.
July 27, 2017
Read More


Novel PET imaging agent could help guide therapy for brain diseases
Researchers have developed a new PET imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis. The agent targets receptors in nerve cells in the brain that are involved in learning and memory.
April 02, 2018
Read More


Misc. - O

Obesity increases dementia risk
People who have a high body mass index (BMI) are more likely to develop dementia than those with a normal weight, according to a new study.
November 30, 2017
Read More


One step closer toward a treatment for Alzheimer's disease?
Novel class of drugs more precisely blocks production of toxic forms of beta-amyloid
October 18, 2017
Read More


Misc. - P

Pathologic hallmarks of Alzheimer's found in aged chimpanzee brains
Humans are considered uniquely susceptible to Alzheimer's disease, potentially due to genetic differences, changes in brain structure and function during evolution, and an increased lifespan. However, a new study provides the most extensive evidence of Alzheimer's disease brain pathology in a primate species to date. Researchers found that the brains of aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer's disease brain.
August 1, 2017
Read More


People 85 and older with high cholesterol have reduced risk for cognitive decline, study reports
High Total Cholesterol in Late Old Age May be Marker Of Protective Factor
March 6, 2018
Read More


People with traumatic brain injury are more likely to be diagnosed with dementia even after 30 years
Let's be clear, though; this is not a causal study
January 30, 2018
Read More


Penn researcher searches for common factor linked to smell loss
Studies have shown that loss of the sense of smell can be among the first warning signs of diseases such as Alzheimer's and Parkinson's. now a researcher at the Perelman School of Medicine at the University of Pennsylvania wants to shift the search for clues about this process back even further, to find out if there is a common factor responsible for the loss of smell that may also serve as an early warning signal for a number of neurodegenerative diseases.
May 10, 2017
Read More


Perineuronal nets essential for distant memories, study shows
How the brain is able to store memories over long periods of time has been a persistent mystery to neuroscientists. In a new study, researchers from the Centre for Integrative Neuroplasticity (CINPLA) at the University of Oslo show that long-lived extracellular matrix molecules called perineuronal nets are essential for distant memories.
December 27, 2017
Read More


Personality changes occur early on during development of Alzheimer's disease, research finds
A key feature of Alzheimer's disease is memory loss and losing one's ability to think and make decisions (also called "cognitive ability"). Those changes can begin slowly, during a phase called "mild cognitive impairment" (or MCI). A variety of diseases can cause MCI, but the most common is Alzheimer's disease.
January 23, 2018
Read More


Physically fit women nearly 90 percent less likely to develop dementia
Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia decades later, compared to women who were moderately fit, according to a new study. The study measured the women's cardiovascular fitness based on an exercise test.
March 15, 2018
Read More


Playing video games may 'enhance learning'
In a learning test, people who play video games performed better than those who don't, and their brains appeared to be more active in regions linked to learning and memory.
October 3, 2017
Read More


Polygenic risk score may identify Alzheimer's risk in younger populations
Early identification may lead to early, more effective treatment
March 5, 2018
Read More


Poor diet may fuel Alzheimer's in people who carry disease-related gene
A diet high in cholesterol, fat and sugar may influence the development of Alzheimer's disease in people who carry the ApoE4 gene, a leading risk factor for the memory-erasing disease, indicates a new USC study.
June 13, 2017
Read More


Poor diet, plus Alzheimer's gene, may fuel disease
Could a healthy diet protect against the onset of Alzheimer's disease?
June 13, 2017
Read More


Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease
A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD). Researchers have found that the molecule memantine stabilizes the development, longevity and function of red blood cells and is well-tolerated by SCD patients.
November 7, 2017
Read More


Postcard from Sacramento: Alzheimer's 'looks like me, it looks like you'
Until last year, Jackie Coleman was a disability rights lawyer -- a good one, too.
January 16, 2018
Read More


Preliminary stages of dementia reduce human face memorization ability
Scientists have revealed that elderly people with mild cognitive impairment (MCI) have a particularly weakened ability to memorize human faces in the short term when compared to healthy elderly people. MCI patients also had a different gaze behavior when trying to memorize a face. This research may lead to the early detection of dementia.
November 22, 2017
Read More


Prevention of vascular risk factors could reduce incidence of Alzheimer's disease
Currently, no possibility exists to reliably quantify the risk of Alzheimer's disease (AD) onset in the general population and in subjects with mild cognitive impairment. Metabolic and genetic factors involved in increasing the probability of developing dementia have already been identified. Some vascular risk factors, as hypertension, dyslipidaemia, diabetes or smoking can cause a derangement in extra or intracranial vessels architecture, which can be responsible for an early aging of the brain. However, reliable tools for early identification of subjects at greater risk of evolution from mild cognitive impairment to AD are not available.
August 2, 2017
Read More


Protein-folding simulations sped up
By modeling biological molecules over longer timescales, a new algorithm can help better understand diseases like Alzheimer's
December 5, 2017
Read More


Proton pump inhibitor use not linked to increased risk of Alzheimer's disease
The use of proton pump inhibitors does not increase the risk of Alzheimer's disease, shows a recent study from the University of Eastern Finland. Proton pump inhibitors are a type of antiulcer drug that is commonly used among older persons.
August 7, 2017
Read More


Proton pump inhibitors do not increase risk for dementia or Alzheimer's disease
Proton pump inhibitors (PPIs) are medications used to treat digestive problems such as ulcers and reflux disease by reducing the body's production of the acid that helps us digest food. Ulcers are sores that develop on the lining of our digestive system; when they develop in the upper part of the small intestine they are called "duodenal ulcers." Reflux disease is a condition in which stomach acid or other fluids in the digestive system irritate our food pipe, also known as the esophagus.
June 22, 2017
Read More


Misc. - R

Reading aloud boosts memory
According to a new study published in the journal Memory, we are more likely to remember something if we read it out loud.
December 28, 2017
Read More


Regular, moderate drinking may increase chances of remaining cognitively healthy in older age
Older adults who consume alcohol moderately on a regular basis are more likely to live to the age of 85 without dementia or other cognitive impairments than non-drinkers, according to a University of California San Diego School of Medicine-led study.
August 1, 2017
Read More


Relative risk of Alzheimer's between men and women: Record corrected
Women genetically predisposed to Alzheimer's are more susceptible than men between ages 65 and 75, researchers discover
August 28, 2017
Read More


Rendering Brain Tissue Transparent with OPTIclear to Unlock Secrets of Alzheimer's and Parkinson's
Researchers from Imperial College London and The University of Hong Kong have published results in Nature Communications of a revolutionary process that renders human brain tissue transparent and allows the complex network of neurons to be mapped.
March 22, 2018
Read More


Research identifies new biomarkers for future dementia risk
Sudha Seshadri, M.D., founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, is co-leader and senior author on research announced March 6 that identifies novel biomarkers of risk for future dementia.
March 6, 2018
Read More


Research: Avocado consumption may lead to improved cognitive function in healthy older adults
Consuming one fresh avocado per day may lead to improved cognitive function in healthy older adults due to increased lutein levels in the brain and eye, according to new research published in the journal Nutrients. The research tracked how 40 healthy adults ages 50 and over who ate one fresh avocado a day for six months experienced a 25% increase in lutein levels in their eyes and significantly improved working memory and problem-solving skills.
August 23, 2017
Read More


Researcher finds that shape of misfolded proteins may contribute to Alzheimer's, Parkinson's and Huntington's disease
Alzheimer's, Parkinson's and Huntington's disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three.
April 02, 2018
Read More


Researchers develop simple method for capturing proteins implicated in Alzheimer's, other conditions
The new methodology involves easily trapping proteins that bear a specific modification that can provide potential markers for conditions. The specific modification is based on sugar and when attached to a protein affects how the protein functions. Protein modification is a normal, carefully regulated cellular function, but in some instances, this can go wrong.
July 17, 2017
Read More


Researchers discover how tau disrupts functioning of nerve cells even before forming tangles
Tau proteins are best known as the proteins that are stacked to form neuronal "tangles" in Alzheimer's patients' brains, but they also play a role in many other brain disorders such as Parkinson's and Huntington's disease. In healthy circumstances, tau proteins are connected to the cytoskeleton of nerve cells, where they support the cells' structural stability. In the nerve cells of patients, however, tau is dislodged from the cytoskeleton and ultimately tangles together to form protein accumulations that disrupt the nerve cell's functioning.
May 19, 2017
Read More


Researchers discover new natural tooth repair method using Alzheimer's drug
A new method of stimulating the renewal of living stem cells in tooth pulp using an Alzheimer's drug has been discovered by a team of researchers at King's College London.
January 9, 2017
Read More


Researchers discover novel genes responsible for Alzheimer's disease
Researchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins in cerebrospinal fluid (CSF).
January 3, 2018
Read More


Researchers discover quirk of cell aging that could help detect late-onset Alzheimer's
Researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Dentistry and McGovern Medical School have discovered a previously unknown characteristic of brain-cell aging that could help detect late-onset Alzheimer's disease decades before symptoms begin.
October 30, 2017
Read More


Researchers explore what happens during break down of nerve cells
A stroke is just one example of a condition when communication between nerve cells breaks down. Micro-failures in brain functioning also occur in conditions such as depression and dementia. In most cases, the lost capacity will return after a while.
September 27, 2017
Read More


Researchers find a potential target for anti-Alzheimer treatments
Scientists have identified a gene that may provide a new starting point for developing treatments for Alzheimer's disease (AD). the USP9 gene has an indirect influence on the so-called tau protein, which is believed to play a significant role in the onset of Alzheimer's disease. this discovery may open a new door to developing active ingredients to treat Alzheimer's disease.
January 11, 2017
Read More


Researchers identify cause of severe genetic disease
Mutations in the p63 protein lead to a number of disorders, but none is as severe as the AEC syndrome. Scientists at Goethe University Frankfurt in collaboration with a research group from the University of Naples Federico II have now discovered that this syndrome resembles diseases such as Alzheimer's, Parkinson's or ALS more closely than it does other p63-based syndromes.
February 2, 2018
Read More


Researchers measure spread of tau protein in the brains of Alzheimer's patients
In a new study presented in Molecular Psychiatry, researchers at Karolinska Institutet have measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer's disease. Their results show that the size of the deposit and the speed of its spread differ from one individual to the next, and that large amounts of tau in the brain can be linked to episodic memory impairment.
May 16, 2017
Read More


Researchers show where in the brain Alzheimer's disease begins
Researchers at Lund University in Sweden have for the first time convincingly shown where in the brain the earliest signs of Alzheimer's occur. The discovery could potentially become significant to future Alzheimer's research while contributing to improved diagnostics.
November 1, 2017
Read More


Researchers spot two genes that influence person's risk of Alzheimer's disease
The new finding, which builds on the team's previous work of identifying 24 susceptibility genes, enables a better understanding of the mechanisms underlying the disease and offers further hope in developing new treatments.
July 17, 2017
Read More


Researchers study molecular mechanisms responsible for Alzheimer's disease
Members of the Faculty of Fundamental Medicine at the Lomonosov Moscow State University have determined the structure of a peptide complex, formed in the brain at the early stages of Alzheimer's disease progression. The research results will contribute to the rational design of compounds, capable to block disease progress.
July 14, 2017
Read More


Researchers win NIH grants for Alzheimer's research on Amish resilience and rapid onset
Researchers from Case Western Reserve University School of Medicine have received two grant awards, in partnership with investigators from other institutions, from the National Institutes of Health to conduct major studies on Alzheimer's disease, the most common form of memory loss and other forms of dementia in older persons.
December 14, 2017
Read More


Retinal Imaging for Alzheimer's Detection
A team of researchers at Cedars-Sinai Medical Center in Los Angeles and NeuroVision Imaging, a Sacramento, California firm, have developed a retinal imaging system that could allow early detection of Alzheimer's disease.
August 22, 2017
Read More


Revising the results of last year's study, Posit Science still effectively combats dementia
Revising the results of their headline-grabbing, decade-long study, researchers from top universities still believe that a brain training exercise from app developer Posit Science can actually reduce the risk of dementia among older adults.
November 16, 2017
Read More


Role for lysosome transport in Alzheimer's disease progression revealed
Researchers have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study suggests that developing ways to restore lysosome transport could represent a new therapeutic approach to treating the neurodegenerative disorder.
August 7, 2017
Read More


Roots of Alzheimer's disease can extend as far back as the womb
Vitamin a deficiency could 'program' brain tissue
January 27, 2017
Read More


Misc. - S

Sad News, Dolphins Get Alzheimer's Disease, Too
It turns out that dolphins are susceptible to Alzheimer's Disease, and I'm not crying, you're crying.
October 24, 2017
Read More


Safe to treat dementia patients with clot-busting drugs, study shows
Stroke patients with dementia treated with intravenous thrombolysis using powerful clot-busting drugs are at no higher risk of brain haemorrhage or death than other patients receiving the same treatment, a new study reports.
October 9, 2017
Read More


Saving neurons may offer new approach for treating Alzheimer's disease
Treatment with a neuroprotective compound that saves brain cells from dying also prevents the development of depression-like behavior and the later onset of memory and learning problems in a rat model of Alzheimer's disease, according to new research.
November 6, 2017
Read More


SBP researchers identify new protective function for brain protein genetically linked to Alzheimer's
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a new protective function for a brain protein genetically linked to Alzheimer's. The findings, published in the Journal of Experimental Medicine, could inform novel treatment strategies.
November 7, 2017
Read More


Scientists discover gene that may open new door to developing treatments for Alzheimer's disease
Scientists at the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have identified a gene that may provide a new starting point for developing treatments for Alzheimer's disease. the USP9 gene has an indirect influence on the so-called tau protein, which is believed to play a significant role in the onset of Alzheimer's disease.
January 11, 2017
Read More


Scientists discover off-switch for 'molecular machine' active in many diseases
A discovery could be the key to stopping damage caused by uncontrolled inflammation in a range of common diseases including liver disease, Alzheimer's and gout. Researchers have uncovered how an inflammation process automatically switches off in healthy cells, and are now investigating ways to stop it manually when it goes awry.
February 6, 2018
Read More


Scientists discover potential brain imaging predictor for early dementia
University of Toronto and Baycrest Rotman Research Institute (RRI) scientists have discovered a potential brain imaging predictor for dementia, which illustrates that changes to the brain's structure may occur years prior to a diagnosis, even before individuals notice their own memory problems.
May 12, 2017
Read More


Scientists find 10 new defense systems used by bacteria
In lab tests, the gene families appear to fight virus attacks
January 25, 2018
Read More


Scientists find two new risk genes for Alzheimer's
New research moves us closer to understanding the genetic underpinnings of Alzheimer's disease, as scientists find two new genes that have been found to raise the risk for the condition.
July 18, 2017
Read More


Scientists find way to recover protein structure after chemical denaturation
Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation. The method is based on electrostatic interaction between folded, or denatured, proteins and alumina, which unwrap them. The authors highlight the versatility of the method: it works for both specific molecules and, for the first time ever, multiprotein systems - nobody has been able to recover mixtures of enzymes before.
June 9, 2017
Read More


Scientists reverse genetic aging, memory decline in rats
As we age, memory function tends to suffer. Understanding and preventing this creeping deficit is a priority for many scientists. Now, a recently published study brings us one step closer.
December 20, 2017
Read More


Scientists stop formation of protein clumps linked to ALS and frontotemporal dementia
Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
August 8, 2017
Read More


Scientists surprised to discover lymphatic 'scavenger' brain cells
The brain has its own inbuilt processes for mopping up damaging cellular waste -- and these processes may provide protection from stroke and dementia. Scientists discovered a new type of lymphatic brain 'scavenger' cell by studying tropical freshwater zebrafish -- which share many of the same cell types and organs as humans.
May 1, 2017
Read More


Scientists Use Light to Erase Unwanted Memories
Researchers at the University of California, Riverside have developed a technique to selectively erase fear memories by weakening connections between the nerve cells involved in forming such memories.
August 22, 2017
Read More


Scientists use novel algorithm to group similar Alzheimer's patients for precise drug trials
The push to develop treatments for Alzheimer's disease has been a promising and disappointing endeavor over the past two decades, yielding a greater understanding of the disease yet still failing to generate successful new drugs.
July 28, 2017
Read More


Security issues with health apps for dementia patients uncovered by researchers
Many health apps designed to assist dementia patients and their caregivers have inadequate security policies or lack security policies altogether, new research concludes.
August 21, 2017
Read More


Sedentary older adults likely to develop dementia as those with genetic risk factors, research finds
Sedentary older adults with no genetic risk factors for dementia may be just as likely to develop the disease as those who are genetically predisposed, according to a major study which followed more than 1,600 Canadians over five years.
January 10, 2017
Read More


Sedatives May Raise Pneumonia Risk in Alzheimer's
Researchers suspect people may breathe saliva or food into their lungs due to fatigue from the drugs
April 10, 2017
Read More


Severe Psoriasis Tied to Risk of Earlier Death
But experts say there may be ways to reduce those odds
September 5, 2017
Read More


Short and long sleep, and sleep disturbances associated with increased risk of dementia and lung cancer
Difficulties in initiating or maintaining sleep at middle-age are associated with an increased risk of dementia, according to a new study. The 20-year follow-up study was conducted among 2,682 men participating the Kuopio Ischaemic Heart Disease Study.
May 24, 2017
Read More


Silent seizures recorded in the hippocampus of two patients with Alzheimer's disease
Seizure-like activity in key memory structure may contribute to cognitive symptoms, offering new therapeutic target
May 1, 2017
Read More


'Silent' Seizures Tied to Alzheimer's Symptoms
Researchers suggest they're a potential target for treating the disease
May 2, 2017
Read More


Simple odor identification tests may help track progression of Alzheimer's disease
Odor identification tests may help scientists track the evolution of the disease in persons at risk
August 16, 2017
Read More


Simple visual processing exercise is the first intervention to limit dementia
Speed training--but not memory or reasoning training--did the trick.
November 22, 2017
Read More


Simulation shows the high cost of dementia, especially for families
A new simulation of the dementia epidemic estimates the economic impact the disease has on households and public insurance programs and provides a tool for projecting the impact that different interventions could have.
August 17, 2017
Read More


Sleep Disturbances Linked to Alzheimer's Risk
Here's another reason to get a good night's sleep: Interrupting a deep phase of sleep appears to cause more of the proteins associated with Alzheimer's disease to collect in your brain, a new study from researchers at Washington University concludes.
July 10, 2017
Read More


Sniffing out dementia with a simple smell test
In a study that followed almost 3,000 older people with normal cognition, researchers found that a simple smell test was able to identify those at higher risk of dementia.
September 29, 2017
Read More


So my brain amyloid level is elevated: What does that mean?
Study illuminates how seniors cope with Alzheimer's-risk biomarker results
October 23, 2017
Read More


Software Predicts Dementia from Amyloid PET Scans
Scientists at McGill University in Canada created a piece of software that can analyze images taken during an amyloid PET scan and provide an estimate of the chances of patients developing dementia. Alzheimer's is associated with the buildup of amyloid plaques within the brain, but interpreting their location and concentrations into clinically useful information is difficult.
August 23, 2017
Read More


Spread of tau protein measured in brains of Alzheimer's patients
Researchers have measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer's disease. Their results show that the size of the deposit and the speed of its spread differ from one individual to the next, and that large amounts of tau in the brain can be linked to episodic memory impairment.
May 16, 2017
Read More


Staying up all night harms women's working memory
Most of us have experienced the "brain fog" that comes after a bad night's sleep. A new study, however, reveals that when it comes to the effect of sleep deprivation on working memory, women fare worse than men.
February 2, 2018
Read More


Stigma associated with Alzheimer's may prevent people from getting early diagnosis, treatment
Stigma associated with Alzheimer's disease may be an obstacle for individuals to seek information about their risk of developing Alzheimer's disease and to participate in clinical studies that discover potential therapies.
March 27, 2018
Read More


Strawberry compound may prevent Alzheimer's
A natural compound found in strawberries and other fruits and vegetables could help to prevent Alzheimer's disease and other age-related neurodegenerative diseases, new research suggests.
July 11, 2017
Read More


Stroke prevention may also reduce dementia
Ontario's stroke prevention strategy is also reducing incidence of dementia among people 80+
May 1, 2017
Read More


Study findings establish basis for epigenetic link between aging and Alzheimer's disease
Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.
March 6, 2018
Read More


Study finds brains of women to be more active than men
In the largest functional brain imaging study to date, the Amen Clinics (Newport Beach, CA) compared 46,034 brain SPECT (single photon emission computed tomography) imaging studies provided by nine clinics, quantifying differences between the brains of men and women. The study is published in the Journal of Alzheimer's Disease.
August 7, 2017
Read More


Study finds evidence on preventive interventions for cognitive decline and dementia
A new report published by the National Academies of Sciences, Engineering, and Medicine shows evidence supporting three interventions for cognitive decline and dementia--cognitive training, blood pressure management for people with hypertension, and increased physical activity, which might slow down cognitive decline and the onset of dementia.
June 26, 2017
Read More


Study finds link between increased brain glucose levels and Alzheimer's
This National Institute on Aging-supported study analyzed the brain tissue samples at autopsy from participants involved in the Baltimore Longitudinal Study of Aging (BLSA). BLSA, which is one of the world's longest-running scientific studies on human aging, records neurological, psychological as well as physical data of participants over many decades.
November 7, 2017
Read More


Study finds no link between exercise in mid-life and cognitive fitness in later years
A study led by Johns Hopkins Bloomberg School of Public Health researchers that tracked activity levels of 646 adults over 30 years found that, contrary to previous research, exercise in mid-life was not linked to cognitive fitness in later years.
August 23, 2017
Read More


Study highlights rate of misdiagnosis in Alzheimer's disease patients with psychosis
People with Alzheimer's disease who experience psychosis--including delusions and hallucinations--are five times more likely to be misdiagnosed with dementia with Lewy bodies compared to patients who do not, new research suggests.
June 30, 2017
Read More


Study identifies potential biomarker for Alzheimer's disease
In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new circulating compounds associated with the risk of developing dementia and Alzheimer's disease (AD). The findings point to new biological pathways that may be implicated in AD and could serve as biomarkers for risk of the disease.
June 12, 2017
Read More


Study offers new insights into brain mechanisms for spatial navigation
An international research team led by UvA researchers Jeroen Bos, Martin Vinck and Cyriel Pennartz has identified a new type of neuron which might play a vital role in humans' ability to navigate their environments. The discovery is an important step towards understanding how the brain codes navigation behaviour at larger scales and could potentially open up new treatment strategies for people with impaired topographical orientation like Alzheimer's patients. The team's results are published in the latest edition of Nature Communications.
May 29, 2017
Read More


Study provides new insight into cells that rejuvenate the brain
Alzheimer's disease is a neurodegenerative disease manifested by various neuronal pathological processes and a significant decline in brain function. Aggregates of beta-amyloid protein ("plaques") accumulate within and between brain cells. Due to both structural changes and the weakening of chemical communication pathways, the junctions of neuronal networks (synapses) are lost. In addition, the cytoskeletal proteins of the axons lose their normal structure, impairing their function and causing massive neuronal death.
June 9, 2017
Read More


Study reveals reduced risk of dementia for physically fit women
Middle aged women with high physical fitness are 90% less likely to develop dementia in the future, according to a recent study.
March 15, 2018
Read More


Study shows clear connection between cardiovascular fitness in middle age and dementia risk
Women who have a high cardiovascular fitness in middle age have a risk of developing dementia when older that is almost 90 percent lower than among women in average physical condition, according to a study published in the journal Neurology.
March 20, 2018
Read More


Study shows feasibility of noninvasive retinal imaging for screening people at risk of AD
Alzheimer's disease (AD) represents the leading cause of dementia worldwide. Currently, challenges in making an early and definitive diagnosis of AD limit opportunities to intervene with disease-modifying therapies before substantial neurodegeneration occurs.
August 17, 2017
Read More


Study shows possibility to reduce antipsychotic use among nursing home residents with dementia
The use of antipsychotic medication in nearly 100 Massachusetts nursing homes was significantly reduced when staff was trained to recognize challenging behaviors of cognitively impaired residents as communication of their unmet needs, according to a new study led by Jennifer Tjia, MD, MSCE, associate professor of quantitative health sciences.
April 17, 2017
Read More


Study to examine how improvisational dance can help people with dementia
Depending on what generation you belong to, the term "improvisational dance" may conjure up images of beatniks grooving to the beat of bongos in a darkened coffeehouse or the black-clad Dieter gyrating to techno pop in a Sprockets sketch on "Saturday Night Live".
July 14, 2017
Read More


Study uses game programming technique to stimulate cognition in older people
Information technology can be a powerful tool for preserving the cognitive functions of people over 60 years of age. This proposition was the basis of Fabio Ota's initiative to test the benefits of teaching game programming techniques to a group of 46 people over the age of sixty, with the aim of developing logical reasoning and preventing cognitive decline.
August 23, 2017
Read More


Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature
A Loyola University Chicago study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a similar ability to cause damage when they invade brain cells.
May 23, 2017
Read More


Study: Lumosity boosts brain function as much as normal video games--by 0%
But taking cognitive tests repeatedly makes you better at taking cognitive tests
July 10, 2017
Read More


Study: People with confusion caused by dementia or delirium have worse treatment outcomes
Hospital patients with dementia and other causes of confusion have longer stays and worse treatment outcomes than people without the condition, research led by the University of Stirling has found.
August 1, 2017
Read More


Survivors of childhood heart defects may have higher risk of premature dementia
Children born with heart defects are more likely to survive into old age because of improved early treatments, but they may be more likely to develop early-onset dementia than people born without heart defects.
February 12, 2018
Read More


Misc. - T

Tau prevents synaptic transmission at early stage of neurodegeneration
Tau proteins are involved in more than twenty neurodegenerative diseases, including various forms of dementia. These proteins clump together in patients' brains to form neuronal tangles: protein aggregation that eventually coincides with the death of brain cells. A research team has now discovered how tau disrupts the functioning of nerve cells, even before it starts forming tangles. They immediately suggest a way to intervene in this process.
May 19, 2017
Read More


TBI and dementia: Link or no link?
Whether or not traumatic brain injury predisposes individuals to dementia has long been under investigation, and the results of different studies are often conflicting. But evidence is mounting that traumatic brain injury can cause long-term damage to the brain.
July 14, 2017
Read More


TBI is associated with increased dementia risk for decades after injury
Traumatic brain injuries increase the risk of a dementia diagnosis for more than 30 years after a trauma, though the risk of dementia decreases over time, according to a new study.
January 30, 2018
Read More


The bacterial 'Game of Thrones'
Understanding bacterial wargames inside our body
January 25, 2018
Read More


The High Costs of Alzheimer's
Sharp increases in Alzheimer's disease cases, deaths and costs are stressing the U.S. health care system and caregivers, a new report reveals.
March 20, 2018
Read More


The lasting effects of ministrokes may contribute to dementia
Investigators report preclinical research showing that microinfarcts induce prolonged dysfunction in brain areas estimated to be 12-times larger than the visible injury site. Data from c-Fos assays and in vivo hemodynamic imaging reveal how individually miniscule microinfarcts might collectively contribute to broader brain dysfunction in patients with vascular cognitive impairment and dementia.
January 16, 2017
Read More


The onset of Alzheimer's disease: The importance of family history
A new study shows that the closer a person gets to the age at which their parent exhibited the first signs of Alzheimer's, the more likely they are to have amyloid plaques, the cause of the cognitive decline associated with the disease, in their brain.
February 26, 2018
Read More


The toxic relationship between ALS and frontotemporal dementia
ALS and frontotemporal dementia (FTD) are two neurodegenerative diseases with a toxic relationship, according to a new study. The study describes how a mutation in a gene, called C9ORF72, leads to toxicity in nerve cells -- causing 10 percent of all cases of ALS, and an additional 10 percent of FTD.
February 5, 2018
Read More


Thin People not More Prone to Alzheimer's
Gene-based research suggests that, instead, early stage disease might cause weight loss
May 9, 2017
Read More


Thinking 'out-of-the-box' may build a better brain and prevent dementia
With disease-modifying treatment trials for Alzheimer's disease (AD) currently unsuccessful and only medications to treat symptoms available, what now? A leading neuroscientist has developed the
September 25, 2017
Read More


This diet may slow cognitive decline after stroke
After showing that the "MIND" diet can reduce the risk of developing Alzheimer's, researchers are now tackling stroke.
January 26, 2018
Read More


Toward an early Alzheimer's test
Researchers have demonstrated the promise of an early blood test for Alzheimer's disease. The results suggest that Alzheimer's can be detected even before the onset of symptoms in persons at genetic risk for Alzheimer's disease.
August 23, 2017
Read More


Trace elements of lithium in drinking water linked to longer life in Alzheimer's patients
Trace elements of lithium in drinking water may slow death rates from Alzheimer's disease, new research suggests. Rates of diabetes and obesity, which are important risk factors for Alzheimer's disease, also decrease if there is a particular amount of lithium in the water, says the study.
December 5, 2017
Read More


Trauma and dementia patients given hope by 'flashbulb memory' breakthrough
Scientists have made a telling breakthrough in detailing the formation of 'flashbulb memories', which can help a snail find a sugary treat but also mean a war survivor repeatedly relives their trauma.
March 9, 2018
Read More


Training And Meds May Help Advanced Alzheimer's
Skills lost, such as dressing or bathing, can potentially be relearned, small study suggests
July 18, 2017
Read More


Two existing drugs halt neurodegeneration in mice
Researchers have made a major leap forward in the treatment of Alzheimer's and Parkinson's, after identifying two existing drugs that prevented brain cell death in mouse models of neurodegenerative disease.
April 20, 2017
Read More


Misc. - U

U.S. Dementia Caregivers Cite Stresses, Rewards
New survey results illustrate the ups and downs of caring for aging family members
October 25, 2017
Read More


UCI researchers aim to identify early indicators of dementia
With $3.8 million in support from the National Institute on Aging, University of California, Irvine neurobiologists are working to identify the early indicators of dementia in older adults as disease-related brain plaques accumulate but before symptoms can be observed.
October 23, 2017
Read More


Using tau imaging as diagnostic marker for Alzheimer disease
The accumulation of β-Amyloid and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tracers, including [18F]-AV-1451, bind to tau in neurofibrillary tangles in the brain. So, could tau imaging become a diagnostic marker for Alzheimer disease and provide insights into the pathophysiology of the neurodegenerative disorder that destroys brain cells?
July 25, 2016
Read More


Using VR to Go Back in Time for Those Living with Alzheimer's
How common is Alzheimer's disease worldwide? What are the main problems faced by individuals living with Alzheimer's Disease?
March 26, 2018
Read More


Misc. - V

Vascular risk factors and Alzheimer's disease: A new therapeutic opportunity?
Currently, no possibility exists to reliably quantify the risk of Alzheimer's disease (AD) onset in the general population and in subjects with mild cognitive impairment. Metabolic and genetic factors involved in increasing the probability of developing dementia have already been identified. Some vascular risk factors, as hypertension, dyslipidaemia, diabetes or smoking can cause a derangement in extra or intracranial vessels architecture, which can be responsible for an early aging of the brain.
August 2, 2017
Read More


Vegetable compound could have a key role in 'beeting' Alzheimer's disease
A compound in beets that gives the vegetable its distinctive red color could help slow the accumulation of misfolded proteins in the brain, a process associated with Alzheimer's disease.
March 20, 2018
Read More


Viral vectors for gene transfer can travel to distant areas in the brain, study shows
Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells. In a study on mice, a team of researchers from Vetmeduni Vienna for the first time investigated how far these viruses spread in the brain and which cells they infect.
June 16, 2017
Read More


Viral vectors for gene transfer travel longer distances in the brain than thought
Gene transfer as a treatment of neurodegenerative diseases
June 16, 2017
Read More


Vitamin B-3 could be used to treat Alzheimer's
New research finds a compound that prevents brain damage in mice. The substance is a form of vitamin B-3, and the findings suggest a potential new therapy for Alzheimer's disease in humans.
February 9, 2018
Read More


VR being used to help scientists diagnose dementia
Sea Hero Quest is a mobile game that helps scientists gather data on dementia -- and the new VR version is expected to give them 15 times the information.
August 30, 2017
Read More


Misc. - W

Walk 4,000 steps every day to boost brain function
Recent research led by the University of California, Los Angeles shows that taking a short walk each day can help to keep the brain healthy, supporting the overall resilience of cognitive functioning.
December 28, 2017
Read More


Western diet increases Alzheimer's pathology in genetically predisposed mice
Obese mice with a particular version of a gene strongly associated with Alzheimer's disease in humans show increased Alzheimer's pathology, according to new research.
June 12, 2017
Read More


What is survival among patients with Parkinson, Dementia with lewy bodies?
A new article compares survival rates among patients with synucleinopathies, including Parkinson disease, dementia with Lewy bodies, Parkinson disease dementia and multiple system atrophy with parkinsonism, with individuals in the general population.
May 15, 2017
Read More


What too much salt can do to your brain
Too much salt can cause cognitive deficits, according to a new study published in the journal Nature Neuroscience. Luckily, these negative effects may be reversed, and the new study shows how.
January 16, 2018
Read More


When is It Worth Worrying About Dementia?
If you didn't know better, you'd think Alzheimer's disease is the plot of a bad horror movie: a creeping silent killer steals your memories, distorts your experiences of the present, and transforms your family's love into dutiful pity.
April 28, 2017
Read More


Why Alzheimer's drugs work in the lab but not in patients
Scientists have found that some potential beta-secretase inhibitors such as semagacestat, which have been used in large clinical trials that ended in failure, do not function as true inhibitors as originally expected, but rather cause accumulation of toxic intraneuronal A?.
October 25, 2017
Read More


Why are African Americans more likely to develop Alzheimer's?
Researchers know that African Americans are at a much higher risk of developing Alzheimer's disease than white Americans. But a new series of studies explores the reasons behind this, analyzing socioeconomic and psychological factors that may play a role.
July 17, 2017
Read More


Women's dementia risk increased by midlife hypertension
Researchers have uncovered a possible sex difference in how blood pressure affects dementia risk, after finding that women who get hypertension in their 40s are likelier to develop the condition. But for men, hypertension in midlife appears to have no impact on dementia risk.
October 5, 2017
Read More


Misc. - X

Xanax, Valium May Boost Pneumonia Risk in Alzheimer's Patients
Researchers suspect people may breathe saliva or food into their lungs due to fatigue from the drugs
April 10, 2017
Read More


The MerchantStore © 1997 - 2018