Health — Cancer — February 2nd, 2026

A 'window to the brain': Chip tracks glioblastoma treatment response using tumor vesicles in blood
Technology created at the University of Queensland could improve the odds of surviving brain cancer and change how we treat a range of neurological conditions. Dr. Richard Lobb and Dr. Zhen Zhang from UQ's Australian Institute for Bioengineering and Nanotechnology have opened a "window to the brain" with a new diagnostic device that can tell how deadly brain tumors respond to treatment from a simple blood test.
February 2, 2026 — Source

How early pregnancy impacts aging: Implications for breast-cancer risk
A new study by cell biologists at the University of California, Santa Cruz, suggests that an early first pregnancy may protect against breast cancer decades later by preventing age-related changes in breast cells that are linked to tumor formation. Using a mouse model designed to mimic human aging and reproductive history, researchers found that pregnancy fundamentally alters how mammary tissue ages—reducing the buildup of abnormal cells that have the ability to change their identity in a way that could seed cancer in later life.
February 2, 2026 — Source

Improving nursing support for fertility preservation in women with cancer
Hiroshima University researchers developed a three-factor, 12-item, questionnaire-based scale to systematically assess nursing practices that support fertility preservation decision-making in women with cancer. They show that such decision-making can be clearly defined, measured, and improved.
February 2, 2026 — Source

Mutation map shows how key cancer gene drives tumor growth
Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein &beta-catenin, which helps regulate tissue growth and repair. When &beta-catenin is disrupted, cells can begin uncontrolled growth—a hallmark of cancer.
February 2, 2026 — Source

New treatment approach boosts survival in young leukemia patients
An Australian research collaboration has led to a major leap forward in the treatment of acute lymphoblastic leukemia (ALL). Recently published clinical trial results have shown evidence that switching part of the standard chemotherapy protocol for a targeted immunotherapy, can significantly improve outcomes for young people living with the disease.
February 2, 2026 — Source

Randomized trial finds drug therapy reduces hot flashes during prostate cancer treatment
A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes compared to the placebo in men receiving hormone therapy for prostate cancer. This primary analysis of Alliance A222001 is published in the Journal of Clinical Oncology.
February 2, 2026 — Source

Scientists create new map showing how cancer gene mutations influence tumor growth
Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth.
February 2, 2026 — Source

Taming tumor chaos: Researchers uncover key to improving glioblastoma treatment
A study by Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer. The findings, published in Cell Reports, reveal how differences among cells within a single tumor influence the cancer's response to chemotherapy, and introduce a promising new therapy designed to tip the odds in the patients' favor.
February 2, 2026 — Source

Health — Cancer — January 31st, 2026

Additional lymph node evaluation needed during surgery to accurately identify lung cancer spread
Breakthrough research presented at the 2026 Society of Thoracic Surgeons Annual Meeting shows that additional lymph node evaluation is needed during surgery for non-small cell lung cancer (NSCLC) to accurately identify cancer spread.
January 31, 2026 — Source

AI support spots 9% more breast cancers without raising false positives
Artificial intelligence helps doctors spot more cases of breast cancer when reading routine scans, a world-first trial found Friday.
January 31, 2026 — Source

Eosinophils suppress tumor growth and recurrence in chordoma
Chordoma is a rare tumor characterized by poor prognosis, limited therapeutic options, and a high rate of recurrence. Despite advances in oncology, effective treatments for chordoma remain limited. Resistance to conventional radiotherapy and chemotherapy restricts therapeutic options, and surgical treatment is often challenging due to the tumor's proximity to critical anatomical structures. Consequently, identifying novel therapeutic targets is essential for improving chordoma diagnosis, treatment strategies, and outcome prediction.
January 31, 2026 — Source

Findings support additional lymph node evaluation to better detect lung cancer spread
Globally, surgical standards vary on the number and location of lymph nodes that should be removed and assessed for metastasis in patients with clinically node-negative NSCLC, cancer that imaging shows has not spread. In North America, surgical standards developed in 2021 call for assessment of three N2 nodes in the mediastinum between the right and left lungs, and one N1 node in the root of the lung.
January 31, 2026 — Source

Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).
January 31, 2026 — Source

New AI tool helps determine the risk of secondary heart attacks in cancer patients
University researchers have pioneered a new tool to determine the risk of secondary heart attacks in cancer patients using Artificial Intelligence.
January 31, 2026 — Source

Health — Cancer — January 30th, 2026

AI tool predicts six-month risks for cancer patients after heart attack
Cancer patients who suffer a heart attack face a dangerous mix of risks, which makes their clinical treatment particularly challenging. As a result, patients with cancer have been systematically excluded from many clinical trials and available risk scores. Until now, doctors had no standard tool to guide treatment in this vulnerable group.
January 30, 2026 — Source

AI-supported mammography improves early detection of breast cancer
Artificial intelligence (AI)-supported mammography identifies more cancers during screening and reduces the rate of breast cancer diagnosis by 12% in the years following, finds the first randomised controlled trial of its kind involving over 100,000 Swedish women published in The Lancet journal.
January 30, 2026 — Source

Gut bacteria may tip the balance between feeding tumors and fueling immunity
A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer, according to researchers at Weill Cornell Medicine. This casts the gut microbiome, comprising the trillions of microorganisms that live in the intestine, as a central player in the body's response to cancer and to modern cancer treatments like immunotherapies.
January 30, 2026 — Source

Researchers develop blood test to find pancreatic ductal adenocarcinoma
National Institutes of Health (NIH)-supported investigators have developed a blood test to find pancreatic ductal adenocarcinoma, one of the deadliest forms of cancer. The new test could improve survival rates from pancreatic cancer, which tends to be diagnosed at late stages when therapy is less likely to be effective. The findings were published in Clinical Cancer Research.
January 30, 2026 — Source

Researchers discover genetic ancestry is a critical component of assessing head and neck cancerous tumors
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).
January 30, 2026 — Source

Researchers identify new blood markers that may detect early pancreatic cancer
NIH-funded, four-marker panel could one day help catch one of deadliest cancers at more treatable stages.
January 30, 2026 — Source

Scientists find hidden pathways pancreatic cancer uses to spread
Researchers have discovered how pancreatic cancer reprograms its surroundings to spread quickly and stealthily. By using a protein called periostin, the tumor remodels nearby tissue and invades nerves, which helps cancer cells travel and form metastases. This process also creates a tough, fibrous barrier that makes treatments less effective. Targeting periostin could help stop this invasion before it starts.
January 30, 2026 — Source

Time of radiotherapy can influence the effectiveness of cancer treatment
A team of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Seville, in collaboration with the Virgen Macarena University Hospital, have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks. This study, which focused on the circadian protein Cryptochrome1 (CRY1), suggests that the time of day when radiotherapy is administered can significantly influence the effectiveness of treatment for certain types of cancer.
January 30, 2026 — Source

Health — Cancer — January 19th, 2026

A new nanorobot designed to improve immune cell recognition could help treat colorectal cancer
Colorectal cancer, the abnormal growth of cancerous cells in the large intestine or the rectum, is one of the most common types of cancers worldwide. Available treatments for this type of cancer include chemotherapy, radiation therapy, surgery and interventions designed to strengthen patients' immune system (i.e., immunotherapies).
January 19, 2026 — Source

A new playbook for cancer prevention in Africa begins with everyday infections
Wits scientists have identified a "microbial watchlist" of bacteria, viruses, fungi and parasites that could cause cancer.
January 19, 2026 — Source

Aging, smoking, oral bacteria and genetic mutations linked to higher stomach cancer risk
Scientists at Duke-NUS Medical School and the National University Health System (NUHS), together with an international team of researchers, have uncovered a complex interplay of factors that increase the risk of developing stomach cancer (gastric cancer).
January 19, 2026 — Source

Lung cancer deaths leveling off for EU women, except in Spain
After increasing for more than 25 years, lung cancer death rates are finally levelling off among women in European Union (EU) countries apart from Spain, according to predictions of mortality rates from the disease for 2026.
January 19, 2026 — Source

New study exposes a targetable vulnerability in acute myeloid leukemia
New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia by identifying the blood cancer's reliance on a specific signaling pathway involved in the body's inflammation response. Their preclinical evidence suggests that blocking this pathway with a new drug compound can weaken acute myeloid leukemia during critical stages, paving the way for more effective and targeted treatments for this hard-to-treat disease.
January 19, 2026 — Source

Plasma protein profiling can help detect cancer in patients with non-specific symptoms
A simple blood test can help detect cancer in patients with non-specific symptoms such as fatigue, pain or weight loss. This is according to a Swedish study from Karolinska Institutet, Danderyd Hospital and others, published in Nature Communications.
January 19, 2026 — Source

Reprogramming the cancer messenger: A new era of tumor extracellular vesicle engineering
Researchers at National Taiwan University have developed a modular platform to reprogram tumor-derived extracellular vesicles (EVs), transforming them from oncogenic messengers into safe, customizable drug delivery vehicles through precise molecular editing.
January 19, 2026 — Source

Spreading drug costs over the year may ease financial burden for Medicare cancer patients
A new study examines the potential impact of the Medicare Prescription Payment Plan (M3P)—an opt-in policy implemented in 2025 under the Inflation Reduction Act that allows beneficiaries to spread out-of-pocket (OOP) costs over the calendar year—on Medicare Part D beneficiaries with cancer who face high out-of-pocket (OOP) prescription drug costs.
January 19, 2026 — Source

Study examines potential impact of the Medicare Prescription Payment Plan on cancer patients
A new study examines the potential impact of the Medicare Prescription Payment Plan (M3P) - an opt-in policy implemented in 2025 under the Inflation Reduction Act that allows beneficiaries to spread out of pocket (OOP) costs over the calendar year - on Medicare Part D beneficiaries with cancer who face high out-of-pocket (OOP) prescription drug costs. Many cancer patients enrolled in Part D incur thousands of dollars in OOP expenses at the start of the year to quickly reach the catastrophic coverage threshold, after which cost-sharing drops to zero. For patients living on fixed or limited incomes, these large upfront payments can be unmanageable, contributing to delayed treatment initiation, medication nonadherence, financial distress and poorer health outcomes.
January 19, 2026 — Source

Weight loss in cancer: Organs respond to the disease in a coordinated way, study finds
Cachexia is a metabolic disorder that causes uncontrolled weight loss and muscle wasting in chronic diseases and cancer.
January 19, 2026 — Source

Health — Cancer — January 14th, 2026

Bacterial toxin can counteract colorectal cancer growth
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden. Systemic administration of the purified bacterial substance changes the immune microenvironment in tumors, and the results may open the way for research into a new type of cancer treatment.
January 14, 2026 — Source

Blood test predicts which patients with lung cancer will benefit from newly approved immunotherapy drug
A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.
January 14, 2026 — Source

ctDNA levels after neoadjuvant therapy may predict breast cancer recurrence better than pathologic complete response
The presence of circulating tumor DNA (ctDNA) in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer after they received neoadjuvant treatment and surgery predicted worse outcomes than in those patients without ctDNA, even in patients with a pathologic complete response (pCR), according to a study published in Cancer Research Communications.
January 14, 2026 — Source

Novel liquid biopsy technology could advance cancer diagnostics and monitoring
A novel liquid biopsy technology is set to advance cancer diagnostics and monitoring by overcoming the long-standing challenge of simultaneously achieving high sensitivity, broad coverage, and simple workflow. A team of researchers from Genomill Health Inc., the University of Turku, and the TYKS Turku University Hospital, Finland, benchmarked this new method, Bridge Capture, against two market-leading tools Their analysis, appearing in The Journal of Molecular Diagnostics, published by Elsevier, highlights the method's simplicity, cost-efficiency, reproducibility, and scalability, making it well suited for routine clinical testing, disease monitoring, and treatment selection.
January 14, 2026 — Source

Scientists identify pre-cancerous states in seemingly normal aging tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.
January 14, 2026 — Source

Health — Cancer — January 9th, 2026

Deep learning creates virtual multiplexed immunostaining to improve cancer diagnosis
Researchers at the University of California, Los Angeles (UCLA), in collaboration with pathologists from Hadassah Hebrew University Medical Center and the University of Southern California, have developed a deep learning--based method that can digitally generate multiple immunohistochemical stains from a single, unstained tissue section.
January 9, 2026 — Source

Immune cell atlas may improve survival predictions, guide treatment decisions in multiple myeloma
A new study maps the immune cell landscape of bone marrow in patients with multiple myeloma, a rare cancer that develops in the plasma cells of the bone marrow and has no cure. This large immune cell atlas, which includes robust patient outcome data, provides unparalleled new insights into how the immune system interacts with cancerous plasma cells and can be used to determine how aggressive a patient's multiple myeloma is likely to be.
January 9, 2026 — Source

Inflammatory immune cells predict survival and relapse in multiple myeloma
A new study maps the immune cell landscape of bone marrow in patients with multiple myeloma, a rare cancer that develops in the plasma cells of the bone marrow and has no cure. This large immune cell atlas, which includes robust patient outcome data, provides unparalleled new insights into how the immune system interacts with cancerous plasma cells and can be used to determine how aggressive a patient's multiple myeloma is likely to be.
January 9, 2026 — Source

Mapping metastasis—how nutrient availability shapes breast cancer's spread
Breast cancer can spread—or metastasize—to many different parts of the body, but it's not well understood why tumors grow better in some organs than others.
January 9, 2026 — Source

New research decodes the bacterial "zip code" of colorectal cancer for prediction and survival
A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how the disease progression and patient outcomes. These "tissue-resident" microbes appear to play an integral role in shaping tumor biology, and can help predict patient survival more accurately than standard clinical factors alone.
January 9, 2026 — Source

Origin cells for common malignant brain tumor in young adults uncovered
IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50. It is a refractory brain cancer that is difficult to treat due to its high recurrence rate.
January 9, 2026 — Source

Personalizing cancer treatments significantly improves outcomes in clinical trial
Researchers at University of California San Diego School of Medicine have led the first clinical trial in the world to show that cancer drug treatments can be safely and effectively personalized based on the unique DNA of a patient's tumor.
January 9, 2026 — Source

Scientists Found a Way to Supercharge the Immune System Against Cancer
Scientists have engineered next-generation antibodies that rally the immune system to hit cancer harder and more effectively.
January 9, 2026 — Source

Single-cell analysis illuminates myeloma immune landscape
Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable. The findings, published in Nature Cancer, provide unprecedented insight on immune dysfunction in myeloma and could lead to improved tools for predicting which patients are at higher risk of relapse after treatment.
January 9, 2026 — Source

Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies
Cancer cells employ a variety of strategies to evade the immune system, and modern immunotherapies aim precisely at these escape mechanisms. However, such therapies are not always successful. A research team led by Herbert-Waldmann at the Max Planck Institute for Molecular Physiology in Dortmund and Georg Winter at the AITHYRA Institute in Vienna has now developed a new class of compounds that specifically target and destroy the enzyme IDO1—a key molecular switch that tumours use to suppress immune responses
January 9, 2026 — Source

Health — Cancer — January 8th, 2026

A double-pronged attack on malignant B cells with improved immunotherapy
Multiple myeloma, a cancer of the bone marrow, remains difficult to treat despite modern CAR T cell therapies. In recent research, a team led by Dr. Armin Rehm presents an improved immunotherapy that recognizes two distinct features of malignant cells to destroy the cancer more effectively.
January 8, 2026 — Source

Bowel preparation for colonoscopies may temporarily alter gut balance, preclinical study suggests
New preclinical research suggests that bowel preparation procedures for colonoscopies may temporarily alter gut balance, culminating in unappreciated effects in patients with compromised gastrointestinal health.
January 8, 2026 — Source

Colonoscopy bowel prep temporarily weakens gut defenses against infection, study finds
New preclinical research suggests that bowel preparation procedures for colonoscopies may temporarily alter gut balance, culminating in unappreciated effects in patients with compromised gastrointestinal health.
January 8, 2026 — Source

Easy-to-use tool can identify high- and low-risk metastatic prostate cancer patients earlier
A new study published in Nature Communications provides a framework for researching whether earlier, model-guided treatment intensification can meaningfully improve survival for patients with aggressive disease.
January 8, 2026 — Source

Engineered protein complex could help immunotherapies target hard-to-treat neuroblastoma
Researchers from Children's Hospital of Philadelphia (CHOP) have developed a method to help cancer immunotherapies reach otherwise "invisible" tumors by helping guide therapies to their appropriate targets. This could be particularly useful for very difficult-to-treat tumors like neuroblastoma. The findings appear in Science Advances.
January 8, 2026 — Source

FDA misses deadline to ban formaldehyde in hair straighteners
The U.S. Food and Drug Administration (FDA) has again missed a deadline to propose a ban on chemicals in hair-straightening products that may pose a serious cancer risk.
January 8, 2026 — Source

Juggling two worlds: Caregivers of leukemia patients struggle to balance care and daily life
Caregivers of individuals diagnosed with acute leukemia face a difficult balancing act: meeting the urgent demands of cancer care while managing their daily responsibilities. A new qualitative study published in the journal Leukemia Research highlights the profound toll of this dual role and underscores the need for caregiver support as an essential part of cancer care.
January 8, 2026 — Source

Just 10 minutes of exercise can trigger powerful anti-cancer effects
A brief, intense workout may do more than boost fitness—it could help fight cancer. Researchers found that just 10 minutes of hard exercise releases molecules into the bloodstream that switch on DNA repair and shut down cancer growth signals. When these molecules were applied to bowel cancer cells, hundreds of cancer-related genes changed activity. The discovery helps explain how exercise lowers cancer risk and hints at future therapies inspired by movement.
January 8, 2026 — Source

Hidden blood mutations linked to higher heart disease risk after cancer treatment
About one in five patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called clonal hematopoiesis of indeterminate potential (CHIP). A study by Vanderbilt Health researchers reveals that it puts them at increased risk for heart disease following cancer treatment.
January 8, 2026 — Source

Multi-pronged antibodies could boost immune response to cancer
Researchers at the University of Southampton have developed a promising new way to bolster the body's immune system response to cancer.
January 8, 2026 — Source

Novel antisense oligonucleotide shows promise against aggressive pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It's also the most common form of the disease. Potential treatments typically target a key mutated oncogene called KRAS. In some cases, PDAC tumors with these mutations have resisted therapeutic efforts. However, combination therapies involving alternative drug targets may one day help clinicians overwhelm these defenses.
January 8, 2026 — Source

Radiotracers could improve choice of bladder cancer therapies
A research team at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) has developed a radiopharmaceutical molecule marker that can visualize tumors that carry the cell surface protein Nectin-4. This primarily occurs in the body in cases of urothelial carcinoma, a common form of bladder cancer.
January 8, 2026 — Source

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment
Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors. CAR-T cell therapy, while highly effective in certain blood cancers, is frequently associated with cytokine release syndrome, neurotoxicity, and prolonged production timelines. These challenges highlight the need for alternative immune cell platforms that retain antitumor potency while reducing clinical risk. Natural killer cells possess inherent cytotoxicity, do not require antigen presentation through major histocompatibility complexes, and rarely cause graft-versus-host disease.
January 8, 2026 — Source

Researchers develop enhanced antibodies to unleash the immune system against cancer
Researchers at the University of Southampton have developed a promising new way to bolster the body's immune system response to cancer.
January 8, 2026 — Source

Seattle's Alpenglow moves 3D microscope tech from lab to clinic to help modernize cancer diagnostics
Seattle-based Alpenglow Biosciences today announced a partnership with PathNet, a leading U.S. pathology laboratory, to help commercialize use of the startup's 3D microscope technology in clinical settings. The effort aims to modernize critical diagnostic tests for prostate and bladder cancers.
January 8, 2026 — Source

Short-circuiting pancreatic cancer: A potential RNA therapy
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It's also the most common form of the disease. Potential treatments typically target a key mutated oncogene called KRAS. In some cases, PDAC tumors with these mutations have resisted therapeutic efforts. However, combination therapies involving alternative drug targets may one day help clinicians overwhelm these defenses.
January 8, 2026 — Source

Unveiling IDH-mutant glioma's roots: A new path for early diagnosis
IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50. It is a refractory brain cancer that is difficult to treat due to its high recurrence rate. Until now, treatment has focused primarily on removing the visible tumor mass. However, a Korean research team has discovered for the first time that normal brain cells acquire the initial IDH mutation and spread out through the cortex long before a visible tumor mass harboring additional cancer mutations forms, opening a new path for early diagnosis and treatment to suppress recurrence.
January 8, 2026 — Source

UVA researcher wins $700,000 for promising ovarian cancer research
Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won $700,000 in support from the Victoria's Secret Global Fund for Women's Cancers in partnership with Pelotonia and AACR, the American Association for Cancer Research.
January 8, 2026 — Source

Walking eases fatigue among colon cancer patients
Regular physical activity—especially walking—can significantly reduce fatigue among people with colon cancer, a new study says.
January 8, 2026 — Source

Health — Cancer — January 7th, 2026

A cancer 'flashlight' helps physicians determine who can benefit from targeted treatments
To determine who could benefit from targeted cancer treatments, a researcher at the University of Missouri has put tumors under a spotlight.
January 7, 2026 — Source

A fresh energy supply may shield nerves from diabetic or chemo-induced neuropathy
Researchers demonstrate that transferring healthy mitochondria from support glial cells to nerve cells could reduce nerve pain and degeneration.
January 7, 2026 — Source

Algorithm matches drugs to glioblastoma's diverse cell types, offering hope for individualized therapies
Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for treating glioblastoma, a lethal brain tumor. This approach enabled them to predict more effective treatment combinations to fight the disease on an individualized basis.
January 7, 2026 — Source

An electronic health record-integrated AI agent advances personalized prostate cancer education
Mayo Clinic researchers have developed and evaluated MedEduChat, an electronic health record (EHR) that works with a large language model to provide accurate, patient-specific prostate cancer education.
January 7, 2026 — Source

Artificial saliva with sugarcane protein shields teeth after cancer treatment
An artificial saliva in the form of a mouthwash, produced with the CANECPI-5 protein extracted from sugarcane and modified in a laboratory, can aid in treating teeth in patients with head and neck cancer. In these cases, radiotherapy very close to the mouth can destroy salivary glands and compromise saliva production, which is essential for controlling bacteria and disease.
January 7, 2026 — Source

BATF2: A novel tumor suppressor silenced by glutamine in head and neck cancer
A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers from The University of Texas MD Anderson Cancer Center.
January 7, 2026 — Source

Brazilian study shows liquid biopsies can expedite lung cancer care
In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for expediting diagnoses and guiding patient treatment. A study supported by FAPESP and published in the journal Molecular Oncology showed that it is possible to identify relevant mutations in blood samples from patients with non-small cell lung cancer (NSCLC) using a commercial multigene panel. Conducted at Hospital de Amor de Barretos, a national oncology reference center, the research evaluated the presence of circulating tumor DNA (ctDNA) in different patient groups, including asymptomatic individuals.
January 7, 2026 — Source

Breakthrough treatment for advanced prostate cancer could eliminate severe side effects
Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.
January 7, 2026 — Source

Can 'Fibermaxxing' Reduce Your Risk of Colorectal Cancer? Registered Dietitians Weigh In
Many Americans aren't getting enough fiber, while colorectal cancer rates are increasing in younger adults. Is fibermaxxing the solution?
January 7, 2026 — Source

Cholesterol-lowering drug can overcome chemotherapy resistance in triple-negative breast cancer, researchers discover
Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer, lacking estrogen, progesterone, and HER2 receptors and thus relying primarily on cytotoxic chemotherapy. Despite initial responsiveness, many patients experience rapid relapse driven by cancer stem-like cells that survive chemotherapy and seed metastasis.
January 7, 2026 — Source or Source

Colon cancer rates are spiking among young people: Here's why, and how to lower the risk
Dr. Bethany Malone has treated a lot of colorectal cancer patients. The youngest, not counting those with genetic conditions, was 19 years old.
January 7, 2026 — Source

Cornell-developed nanoparticles improve cancer immunotherapy effectiveness
A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy, according to a new study led by Weill Cornell Medicine and Cornell Engineering researchers.
January 7, 2026 — Source

Cracking prostate cancer's code: An enzyme's central role in controlling subtypes and improving therapeutic response
A large team of researchers led by Wouter Karthaus, head of the Endocrine Therapy Resistance and Molecular Genetics Lab at EPFL, and Eneda Toska at Johns Hopkins University have identified the enzyme KMT2D as a key epigenetic regulator in prostate cancer. Their study published in Cancer Research reveals that KMT2D plays a central role in shaping how prostate tumors grow, survive, and respond to therapy.
January 7, 2026 — Source

High glutamine levels suppress immune response in head and neck cancer tumors
A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers from The University of Texas MD Anderson Cancer Center.
January 7, 2026 — Source

Magnetic nanoparticles fight bone cancer and help healing
Researchers have developed a magnetic nanomaterial that can kill bone cancer cells and support bone regeneration at the same time. The material heats up under a magnetic field to destroy tumors, while its bioactive coating helps it bond to bone and stimulate healing. Tests showed rapid formation of bone-like minerals, a key sign of successful integration. The breakthrough could lead to smarter, less invasive treatments for bone tumors.
January 7, 2026 — Source

MD Anderson and SOPHiA GENETICS join forces to accelerate data-driven cancer care
The University of Texas MD Anderson Cancer Center and SOPHiA GENETICS today announced a strategic collaboration that unites SOPHiA GENETICS' AI-powered analytics with MD Anderson's clinical and scientific expertise to accelerate data-driven cancer care through new tools that can accurately analyze, interpret and translate diagnostic results into clinical practice.
January 7, 2026 — Source

Novel approach uncovers possible drugs based on specific cellular targets for treating glioblastom
Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for treating glioblastoma, a lethal brain tumor. This approach enabled them to predict more effective treatment combinations to fight the disease on an individualized basis. This laboratory and computational research effort was led by scientists at Georgetown's Lombardi Comprehensive Cancer Center.
January 7, 2026 — Source

Ozempic, Wegovy might lower colon cancer risk
Ozempic and Wegovy might help people avoid colon cancer as well as promote weight loss or control diabetes, a new study says.
January 7, 2026 — Source

Q&A: How tumor support cells help lung cancer evade targeted therapy
A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated fibroblasts, can help lung cancer cells survive targeted drug therapy by activating multiple survival routes that allow tumors to evade treatment.
January 7, 2026 — Source

Study links dozens of blood proteins to prostate cancer risk across populations
A large-scale study has identified dozens of blood proteins linked to prostate cancer risk, some shared across populations, some unique to specific groups.
January 7, 2026 — Source

Treatment developed for advanced prostate cancer that could eliminate severe side effects
Researchers at Case Western Reserve University have developed a treatment for advanced prostate cancer that could eliminate a side effect so debilitating that patients often refuse the life-saving therapy.
January 7, 2026 — Source

Uncovering why cancer immunotherapy leads to heart inflammation
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by using the patient's own T-cells to target tumors. However, they can cause rare, but potentially fatal cardiac inflammation known as ICI-myocarditis. This is particularly true in the most recent ICI combination treatment of targeting proteins LAG-3 and PD-1, according to new research.
January 7, 2026 — Source

Young cancer survivors may face faster aging and possible early-onset dementia
Adolescent and young adult cancer survivors age faster than their peers who did not have cancer, according to a new study, which also describes how accelerated aging occurs both at the cellular level and in brain function, such as memory, attention, and ability to process information.
January 7, 2026 — Source

Health — Cancer — January 6th, 2026

AI-designed nanosensors could enable at-home testing for early cancer detection
Nanoparticles coated with molecular sensors could be used to develop at-home tests for many types of cancer.
January 6, 2026 — Source

Immune sabotage: How a Vitamin A byproduct compromises the body's normal anti-cancer response
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic acid—compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.
January 6, 2026 — Source

Nanoparticles Show Unexpected Ability to Activate Immune System Against Melanoma
Cornell-developed "prime dots" trigger immune activation by reshaping the tumor microenvironment.
January 6, 2026 — Source

Nanoparticles with AI-crafted sensors open paths to at-home cancer screening
Detecting cancer in the earliest stages could dramatically reduce cancer deaths because cancers are usually easier to treat when caught early. To help achieve that goal, MIT and Microsoft researchers are using artificial intelligence to design molecular sensors for early detection.
January 6, 2026 — Source

Novel analysis shows promise for revealing early ovarian cancer signals
University of Manchester researchers have shown that analysis of fluid flushed through a fallopian tube holds promise for providing insights into molecular changes linked to early ovarian cancer development.
January 6, 2026 — Source

Seeing thyroid cancer in a new light: When AI meets label-free imaging in the operating room
Thyroid cancer is the most common endocrine cancer, affecting more people each year as detection rates continue to rise. During tumor excision, surgeons often struggle to determine exactly how much tissue should be removed, as distinguishing cancer from healthy tissue in real time is challenging and nearby structures are extremely delicate.
January 6, 2026 — Source

Streptococcus anginosus metabolites fuel gastric cancer
A recent study published in the medical journal Gut has revealed a novel cancer-promoting mechanism of Streptococcus anginosus (Sa). The research shows that methionine metabolites produced by this bacterium can significantly contribute to the development of gastric cancer.
January 6, 2026 — Source or Source

Study confirms high cost effectiveness of prostate cancer screening
A research team from the Department of Surgery and the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has demonstrated that prostate-specific antigen (PSA) screening for men aged 45 and above can significantly reduce the incidence of advanced-stage prostate cancer from 39% to approximately 1%, and lower the mortality rate from 6.14% to 2.85%.
January 6, 2026 — Source

Study underscores role of sleep in reducing toll of social adversity on breast cancer survivors' health
Where someone lives can affect their health. For breast cancer survivors, their neighborhood can influence their recovery from treatment.
January 6, 2026 — Source

Ultrasmall silica nanoparticles boost immune response against melanoma
A class of ultrasmall fluorescent core-shell silica nanoparticles is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy.
January 6, 2026 — Source

US backs at-home HPV testing to boost cervical cancer screening
Federal health officials say self-collected vaginal samples can now be used to screen for cervical cancer, and most private insurance plans will be required to cover the testing without charging patients out of pocket.
January 6, 2026 — Source

Using contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factors
Announcing a new article publication for BIO Integration journal. Hepatic perivascular epithelioid cell tumor (PEComa) is a rare tumor with malignant potential that is frequently misdiagnosed as hepatocellular carcinoma (HCC), despite requiring distinct treatment approaches. This study retrospectively investigated the imaging characteristics of PEComa and HCC without high-risk factors using conventional ultrasound (CUS) and contrast-enhanced ultrasound (CEUS) to improve preoperative diagnostic accuracy.
January 6, 2026 — Source

Health — Cancer — January 5th, 2026

Combination therapy against brain cancer proves effective in preclinical models
Researchers at the UNC School of Medicine and the UNC Eshelman School of Pharmacy have made a breakthrough that could modernize treatment for glioblastoma. In a study published in Proceedings of the National Academy of Sciences, they found that combining a common chemotherapy drug with a chemical called EdU provided unprecedented survival and cancer remission in various preclinical glioblastoma models.
January 5, 2026 — Source

Fatigue before cancer treatment linked to adverse events
Fred Hutchinson Cancer Center-led investigators found that higher patient-reported fatigue before cancer treatment aligned with higher odds of severe, life-threatening, and fatal treatment-related toxic effects.
January 5, 2026 — Source

For the first time, a mechanism enabling breast cancer to metastasize to the brain has been deciphered
A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv University, has uncovered a mechanism that allows breast cancer to send metastases to the brain—a highly lethal occurrence for which there is currently no effective treatment. The findings could enable the development of new drugs and personalized monitoring for early detection and treatment of brain metastases.
January 5, 2026 — Source

Hot flash drug shows added anti-cancer effect in breast cancer treatment
A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen treatment for women with breast cancer, a new Cambridge-led trial has found.
January 5, 2026 — ASUS unveils ROG XREAL R1 AR gaming glasses offering 171-inch virtual screen for handhelds, PCs and consoles
ASUS is bringing XREAL-branded AR gaming glasses to CES with the ROG XREAL R1. ASUS says the glasses use a 240Hz micro-OLED display with FHD (1920×1080) resolution, aimed at turning a PC, console, or handheld into a large virtual screen.
January 5, 2026 — Source

Inhalable nanotherapy can activate the immune system against checkpoint-resistant melanoma
Immune checkpoint molecules play a crucial role in keeping the immune system in balance and preventing an attack on the body's own cells. Cancer cells can use these checkpoints to hide from the immune system, making them a key focus for treatments that boost the immune response against cancer. Immune checkpoint inhibitors are proteins that release this brake on the immune system and unleash our immune cells to attack tumors.
January 5, 2026 — Source or Source

Molecular mechanism reveals how viral infection triggers aggressive leukemia
Researchers at Kumamoto University have uncovered a previously unknown molecular mechanism by which human T-cell leukemia virus type I (HTLV-1) drives the development of adult T-cell leukemia-lymphoma (ATL), one of the most aggressive and difficult-to-treat blood cancers. The findings provide critical insight into why only a small fraction of HTLV-1 carriers develop leukemia—and point toward new strategies for targeted therapy.
January 5, 2026 — Source

Retrotransposon drives cancer by altering 3D genome structure
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons are mobile DNA pieces, comprising much of the human genome. These so-called "jumping genes" can copy and insert themselves throughout the genome, contributing to various diseases, including cancer.
January 5, 2026 — Source

Tiny fluorescent core-shell silica nanoparticles supercharge cancer immunotherapy
A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy, according to a new study led by Weill Cornell Medicine and Cornell Engineering researchers.
January 5, 2026 — Source

Health — Cancer — January 2nd, 2026

A mathematical solution for precise control of cellular "noise"
Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.
January 2, 2026 — Source

AI detects stomach cancer risk in remote communities from upper endoscopic images
In many regions, doctors practice in settings with limited medical resources. Advanced tests, specialist support, and expert guidance for complex decisions are often unavailable. Under these circumstances, accurate automated systems, especially AI, can help close the gap between limited resources and clinical needs.
January 2, 2026 — Source

AI model predicts B cell reactivity to neoantigens for improved cancer vaccines
Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move beyond one-time attacks and short-term memory to become a long-term immunity that "remembers" cancer, effectively preventing recurrence. KAIST's research team has developed an AI-based personalized cancer vaccine design technology that makes this possible and optimizes anticancer effects for each individual.
January 2, 2026 — Source

Elevated bacteria levels in tumors weaken immune response, studies show
Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.
January 2, 2026 — Source

Nanoparticle therapy reprograms tumor immune cells to attack cancer from within
Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor. A KAIST research team led by Professor Ji-Ho Park of the Department of Bio and Brain Engineering have overcome this limitation by developing a new therapeutic approach that directly converts immune cells inside tumors into anticancer cell therapies.
January 2, 2026 — Source

Newly identified rare genetic variant reduces the risk of leukemia
A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia. The findings offer insight into why some people are naturally more resistant to clonal expansion and age-related blood cancers despite acquiring risky mutations. As tissues age, they quietly accumulate many mutations that can drive cancer. In the blood-forming, or hematopoietic, system, such mutations often appear in otherwise healthy individuals as clonal hematopoiesis (CH), a process in which certain blood stem cell (HSC) clones gain a growth advantage over non-mutated clones, allowing them to expand steadily over time.
January 2, 2026 — Source

New therapeutic approach converts immune cells inside tumors into anticancer cell therapies
Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor. KAIST researchers have overcome this limitation by developing a new therapeutic approach that directly converts immune cells inside tumors into anticancer cell therapies.
January 2, 2026 — Source

Short, intensive workouts can help fight bowel cancer
As many of us embark on an exercise or gym routine for the new year, research reveals that just 10 minutes of intense exercise could help fight cancer.
January 2, 2026 — Source

Tumor bacteria linked to immunotherapy resistance in head and neck cancer
Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.
January 2, 2026 — Source

Health — Cancer — December 26th, 2025

Nanosensors reveal if immunotherapy is working days before tumors respond
Gold nanoparticles that cluster in response to T cell enzymes can predict cancer immunotherapy success days before tumors begin to shrink.
December 26, 2025 — Source

Health — Cancer — December 25th, 2025

Scientists develop targeted therapy for T-cell lymphomas and leukemias
Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive tumors.
December 25, 2025 — Source

Health — Cancer — December 21st, 2025

A new tool is revealing the invisible networks inside cancer
A new open-source tool is peeling back cancer's genetic "black box," revealing hidden molecular networks that shape survival and disease progression.
December 21, 2025 — Source

Accelerated cancer drug approvals yield modest survival gains at significant Medicare cost
Researchers found that between 2012 and 2020, 178,000 Medicare beneficiaries received early access to cancer drugs through the FDA's accelerated approval pathway. While the pathway aims to give patients faster access to promising treatments, fewer than half of these drugs were later shown to help people live longer.
December 21, 2025 — Source

Health — Cancer — December 19th, 2025

30-year smoking duration-based criteria could increase lung cancer screening
Thirty-year smoking duration-based criteria could reduce eligibility gaps for all races relative to whites, while improving six-year lung cancer detection sensitivity, according to a study published online Dec. 16 in the Annals of Internal Medicine.
December 19, 2025 — Source

Cancer's hidden 'safety switch': Silencing TAK1 gene could boost immunotherapy performance
Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing a mechanism that may limit the effectiveness of immunotherapy treatments.
December 19, 2025 — Source

Comprehensive study settles debate over diet safety for patients with cancer
For decades, patients undergoing blood cancer treatment have been told to avoid certain foods to reduce infection risk, guidance that some physicians hoped could safely be relaxed. Now, a University of Florida study offers clear evidence that a diet designed to limit exposure to foodborne microbes results in fewer serious infections, confirming it is still the safest choice.
December 19, 2025 — Source

Discovery turns household plastic recycling into anti-cancer medication
A discovery led by the University of St Andrews has found a way to turn ordinary household plastic waste into the building block for anti-cancer drugs.
December 19, 2025 — Source

Genomic test helps flag early aggressive prostate cancer in African American patients
A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face the highest burden from this disease.
December 19, 2025 — Source

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue
A University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their metabolism to thrive in bone tissue, offering a potential new treatment target for patients with advanced disease.
December 19, 2025 — Source

Health — Cancer — December 15th, 2025

Blood test may help identify which colon cancer patients benefit from NSAIDs
A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to a study appearing in JAMA Oncology. Based on data from an Alliance for Clinical Trials in Oncology study, this finding could lead to more personalized treatments and better outcomes for patients.
December 15, 2025 — Source

Cancer disrupts brain's day-night rhythm, altering stress hormone cycles in mice
"The brain is an exquisite sensor of what's going on in your body," says Cold Spring Harbor Laboratory Assistant Professor Jeremy Borniger. "But it requires balance. Neurons need to be active or inactive at the right times. If that rhythm goes out of sync even a little bit, it can change the function of the entire brain."
December 15, 2025 — Source

Cannabis compounds show unexpected power against ovarian cancer
Cannabis compounds CBD and THC show early but compelling promise as a future ovarian cancer therapy.
December 15, 2025 — Source

Fertility gene helps glioblastoma tumors survive chemotherapy and return after treatment, researchers discover
Research by University of Sydney scientists has uncovered a mechanism that may explain why glioblastoma returns after treatment, offering new clues for future therapies which they will now investigate as part of an Australian industry collaboration.
December 15, 2025 — Source

New guideline maps care for pregnant women with blood cancers
A new guideline from the American Society of Clinical Oncology (ASCO) offers clear, evidence-based direction for treating blood cancers during pregnancy and shows that many patients can safely receive timely cancer care without compromising fetal health. The guideline underscores that survival outcomes for pregnant patients with leukemia or lymphoma can match those of non-pregnant patients when treatment follows established protocols.
December 15, 2025 — Source

Health — Cancer — December 12th, 2025

Acupuncture improves breast cancer survivors' perceived cognitive impairment
Real and sham acupuncture were more effective at improving breast cancer survivors' perceived cognitive impairment compared with usual care, while real acupuncture was superior to sham acupuncture in improving objective cognitive function, according to results from the randomized ENHANCE phase II clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.
December 12, 2025 — Source or Source

Adding antibody treatment to chemo boosts outcomes for children with rare cancer
Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical trial.
December 12, 2025 — Source

It's being used to fight cancer, flu and the next pandemic, but what exactly is mRNA?
Aside from maybe high school biology classes, the first time many people heard of mRNA was during the pandemic because of the vital role MRNA technology played in COVID-19 vaccines.
December 12, 2025 — Source

Menopausal hormone therapy shows no added breast cancer risk for BRCA carriers
Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited mutations in the BRCA1 or BRCA2 genes, according to the results of a matched prospective analysis presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.
December 12, 2025 — Source or Source

Mini-tumors combine synthetic and real cells to simulate immune responses
Normally, the immune system recognizes and eliminates abnormal cells. However, cancer cells can develop strategies to evade this control: they block defense mechanisms or send inhibitory signals. In this way, tumors can grow unchecked. In a collaborative study, research teams from Germany, the United Kingdom, and Hungary have tackled this challenge by creating artificial tumor models in which synthetic cells mimic immune responses.
December 12, 2025 — Source

Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors
Incidence of breast cancer in women between the ages of 15 and 39 has risen on average 0.6% each year between 1975 and 2022.
December 12, 2025 — Source or Source

New immunotherapy targets for glioblastoma identified by mapping cell interactions
Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and chemotherapy), fewer than half of patients will survive longer than 15 months. Only 5% of patients survive longer than five years.
December 12, 2025 — Source

Study shows IL-36 gamma 'armored' CAR T cells can eradicate solid tumors
A laboratory study out of Roswell Park Comprehensive Cancer Center outlines a new way to boost the effectiveness of chimeric antigen receptor (CAR) T-cell therapy in solid-tumor cancers, resulting in their eradication. Led by Renier Brentjens, MD, Ph.D., Deputy Director and Chair of the Department of Medicine at Roswell Park and a pioneer in the field of CAR T-cell therapy, the research represents a hopeful new step toward achieving the same success in solid tumors that the treatment has realized in hematologic malignancies.
December 12, 2025 — Source

Tanning Beds Are Giving Us Skin Cancer Where the Sun Doesn't Shine
New research highlights the unique dangers of the UV radiation provided by tanning beds.
December 12, 2025 — Source or Source

Health — Cancer — December 11th, 2025

Antibody formulation could enable simple injections instead of lengthy hospital infusions
Antibody treatments for cancer and other diseases are typically delivered intravenously, because of the large volumes that are needed per dose. This means the patient has to go to a hospital for every treatment, where they may spend hours receiving the infusion.
December 11, 2025 — Source

Blocking collagen signaling boosts drug delivery in pancreatic cancer
Pancreatic cancer is one of the deadliest malignancies, with survival rates remaining dismally low despite major advances in oncology. One of the key reasons lies in the disease's unique fibrotic microenvironment—a dense, collagen-rich tissue that acts as a physical and biochemical barrier, preventing drugs from reaching tumor cells effectively.
December 11, 2025 — Source or Source

CAR-T therapy yields long-term survival for patients with lymphoma
A study published in the Journal of Clinical Oncology confirms that one of the first Food and Drug Administration-approved CAR-T cell therapies offers long-term survival and potential cures for adult patients with relapsed or refractory large B-cell lymphoma, even years after treatment.
December 11, 2025 — Source

Even moderate drinking carries a bigger cancer risk than you think
Alcohol's cancer risk is shaped by a powerful mix of biology, behavior, and social factors—often in ways people don't expect.
December 11, 2025 — Source

Frequency and quantity of alcohol consumption influence cancer risk
As Americans gear up for the holiday season, new research offers a timely reminder to reflect on the long-term health effects of raising a celebratory glass -- or two. Alcohol is known to increase the risk of several cancers even at moderate levels. Yet drinking remains widespread, and important questions persist about how both the frequency and amount of alcohol people consume shape their cancer risk.
December 11, 2025 — Source

Imaging study solves a long-standing gap in metastatic breast cancer research and care
A prospective, multicenter cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) has validated an improved method for predicting treatment benefits in patients with hormone receptor-positive (HR+) metastatic breast cancer that has spread primarily or exclusively to the bones.
December 11, 2025 — Source

Phase I trial finds breast cancer vaccine triggers an immune response and is safe
Cleveland Clinic researchers are presenting final Phase I data from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.
December 11, 2025 — Source

Preoperative radiation may enhance treatment response in patients with HR-positive, HER2-negative breast cancer
Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led to improved treatment responses prior to surgery, according to the results of the phase II P-RAD clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.
December 11, 2025 — Source

Researchers discover the enzyme responsible for chromothripsis in cancer
University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment. Since its discovery more than a decade ago, chromothripsis has emerged as a major driver of cancer progression and treatment resistance, but scientists haven't learned what causes it. Now, UC San Diego scientists have solved this longstanding mystery in cancer biology, opening up new possibilities for treating the most aggressive cancers.
December 11, 2025 — Source

Scientists uncover key driver of treatment-resistant cancer: Genome-scrambling enzyme points to new treatments
University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.
December 11, 2025 — Source

Skipping sentinel lymph node biopsy may be safe for some early-stage breast cancer patients
Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative, hormonal receptor (HR)-positive, HER2-negative early-stage breast cancer did not compromise regional control or survival after a median five years of follow-up, according to results from the BOOG 2013-08 phase III clinical trial, presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.
December 11, 2025 — Source

Software Mogul/Secretary of (*checks notes) the Interior Says AI Will Cure Cancer
"This is the miracle of AI. We can actually manufacture intelligence."
December 11, 2025 — Source

Tricking tumors into marking themselves for destruction with focused ultrasound
The research team from USC Viterbi's Wang Lab used focused ultrasound waves to "prime" tumor cells so they can be more easily recognized and attacked by chimeric antigen receptor (CAR) T-cells, the engineered immune cells that have revolutionized treatment for blood cancers but have until now struggled against solid tumors.
December 11, 2025 — Source

Trump Rules Force Cancer Registries To 'Erase' Trans Patients From Public Health Data
LISTEN: "People get better care when we know who they are." That belief is at the heart of why scientists and LGBTQ+ health advocates oppose a new rule that makes it harder to collect data on trans patients with cancer. KFF Health News correspondent Rachana Pradhan appeared on WAMU's Health Hub on Dec. 10 about the change from the Trump administration.
December 11, 2025 — Source

Valvular heart disease is common in cancer patients but interventions can improve survival
Valvular heart disease, identified through cardiovascular imaging, is common in cancer patients. Interventions to treat valvular heart disease significantly improved survival.
December 11, 2025 — Source

Health — Cancer — December 5th, 2025

AI brain scan model identifies stroke, brain tumors and aneurysms
A new AI model could help radiologists identify brain abnormalities in MRI scans for all conditions including stroke, multiple sclerosis and brain tumors.
December 5, 2025 — Source

Gut bacteria's hidden toxin acts as DNA glue, fueling colorectal cancer risk
Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable bacterial product causes mutations in DNA that have been linked to colorectal cancer. Because it breaks down quickly, isolating and studying it has been difficult, but now scientists in the U.S. have discovered exactly how colibactin attacks DNA.
December 5, 2025 — Source

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival
UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.
December 5, 2025 — Source

New combination treatment helps people with recurring grade 3 astrocytoma, trial shows
Huntsman Cancer Institute at the University of Utah (the U) participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma, an aggressive form of brain cancer, live longer.
December 5, 2025 — Source

New targeted alpha therapy shows promise for patients with radioiodine-refractory thyroid cancer
A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs. The findings were published in the December issue of The Journal of Nuclear Medicine.
December 5, 2025 — Source

Next gen cancer drug shows surprising anti aging power
A next-gen drug and a surprising enzyme system reveal new clues about how aging may be slowed.
December 5, 2025 — Source

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies. Even when patients initially respond to treatment, the cancer often returns and is more resistant than before.
December 5, 2025 — Source

Order of cancer-driving mutations affects the chance of tumor development, study shows
The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals.
December 5, 2025 — Source

Saliva and plasma at the core of cancer detection and treatment
Saliva and plasma could be crucial in detecting recurrences or relapses of head and neck cancers, negating the need for a painful and invasive biopsy.
December 5, 2025 — Source

Structure of protein reveals how breast cancer cells survive in hostile conditions
UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.
December 5, 2025 — Source

Health — Cancer — December 3rd, 2025

A common childhood virus can drive bladder cancer development
Tackling a common childhood virus could open the door to preventing bladder cancer, according to new research.
December 3, 2025 — Source

A personalized approach to treating pancreatic cancer
It's not surprising that pancreatic cancer is often referred to as a silent killer. With few early symptoms and an aggressive nature, it has one of the lowest survival rates of all cancers.
December 3, 2025 — Source

Breast cancer reshapes lymphatic vessels to support its spread
Breast cancer is able to modify the lymphatic vessels through which it travels to the draining lymph nodes. From there, it can then spread to other parts of the body. A new finding by Finnish researchers may help develop targeted therapies that could prevent this spread.
December 3, 2025 — Source or Source

Chemists synthesize a fungal compound that holds promise for treating brain cancer
For the first time, MIT chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent.
December 3, 2025 — Source

New investment aims to accelerate treatments for low-grade brain tumors
Researchers focused on accelerating and testing new treatments for low-grade brain tumors are set to receive a transformative £2.8 million to drive their future work.
December 3, 2025 — Source

Newly defined benign soft tissue tumor with bony shell may mimic malignancy
It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring. But thanks to a Johns Hopkins Medicine doctor and his newly reported definition and classification of a previously unknown, novel type of benign soft tissue tumor, that's exactly the desired outcome.
December 3, 2025 — Source

Researchers reveal complex interactions between heart disease and cancer
A surprising new discovery by Prof. Ami Aronheim and his team at the Technion--Israel Institute of Technology shows that in the absence of anti-cancer treatments, cancer development may actually improve heart function and reduce fibrosis—the scarring process that stiffens the heart muscle.
December 3, 2025 — Source

Small team, big impact: Automation helps relieve symptoms to keep cancer patients out of the ER
For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an emergency room visit. Such visits can be financially costly and take an emotional toll on patients and their caregivers.
December 3, 2025 — Source

Sneaky senescent cells that resist cancer treatment can provide druggable lung cancer target
Senescent fibroblasts are aging cells that no longer divide and protect against tumor development. Yet two decades have gone by since cell biologist Judith Campisi, Ph.D., paradoxically demonstrated that these same cells can promote cancer growth in a laboratory setting. Until now, it has not been clear whether this occurs inside the body.
December 3, 2025 — Source

Two genes found to suppress colorectal cancer spread in preclinical models
Cancer is a leading cause of death worldwide, and among all cancers, colorectal cancer ranks second in mortality, responsible for more than 900,000 deaths in 2020.
December 3, 2025 — Source

Women who receive mammograms also undergo lung scans if notified of eligibility
While most women over age 50 schedule mammograms for breast cancer, only a minority who are also eligible for low-dose CT scans for lung cancer undergo those potentially lifesaving screenings. A new study shows that targeted outreach can close the gap.
December 3, 2025 — Source

Health — Cancer — November 30th, 2025

Your skin has a built-in cancer defense and sunlight turns it off
Scientists have uncovered how too much sunlight can flip a hidden switch inside skin cells that makes inflammation spiral out of control and increases the risk of cancer. Their research reveals that UV radiation breaks down a protective protein called YTHDF2, which normally prevents a small RNA signal from activating an immune sensor linked to dangerous inflammation. Once that protection is lost, a surprising chain reaction unfolds inside the cell, turning ordinary sun damage into a potential cancer trigger.
November 30, 2025 — Source

Health — Cancer — November 29th, 2025

Predicting a rare but life-altering complication of common cancer treatment
A new study published in the Journal of Clinical Investigation has identified biomarkers that predict the likelihood of a patient developing checkpoint inhibitor-associated autoimmune diabetes before they are treated with immune checkpoint inhibitors. Australian researchers say identifying those at high risk of the condition would allow for earlier and closer monitoring and potentially reduce the number of people presenting with serious complications like diabetic ketoacidosis.
November 29, 2025 — Source

Health — Cancer — November 26th, 2025

AI tops density in predicting breast cancer risk
An image-only artificial intelligence (AI) model for predicting the five-year risk of breast cancer provided stronger and more precise risk stratification than breast density assessment, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).
November 23, 2025 — Source

Copper nanoparticles emerge as a strong metal platform for UV SERS
Researchers show copper nanoparticles power UV SERS to detect key biochemical markers, a discovery that could pave the way to fast and reliable skin cancer diagnostics.
November 23, 2025 — Source or Source

High risk of metastatic recurrence found among young cancer patients
A new study of adolescents and young adults (AYAs) with seven common cancers reveals that nearly one in ten patients diagnosed with non-metastatic disease later develop metastatic recurrence—a condition associated with significantly worse survival outcomes. Metastasis is when cancer cells spread from the initial or primary site to other parts of the body. It comes with significantly worse survival outcomes.
November 23, 2025 — Source

Missing cancer gene explains why some lung tumors respond well to immunotherapy
For some patients with the most common type of lung cancer, known as lung adenocarcinoma, there's new hope. In a new study published in Cell Reports, Mayo Clinic researchers have found several previously unknown genetic and cellular processes that occur in lung adenocarcinoma tumors that respond well to immunotherapy.
November 23, 2025 — Source

New microprotein can help cancer cells overcome stress
Cell stress and protein misfolding are involved in many diseases, including cancer and neurodegenerative disorders, and the study could one day contribute to new therapeutic strategies.
November 23, 2025 — Source

Rare inherited variants shape risk and outcomes in pediatric brain and spinal cord tumors
Researchers at Children's Hospital of Philadelphia (CHOP) and Children's National Hospital in Washington D.C. are uncovering how rare inherited genetic variants contribute to the development of brain and spinal cord tumors in children. The findings, published in the journal Nature Communications, provide new insights into how a child's genetic makeup influences cancer risk and outcomes.
November 23, 2025 — Source

Study finds uneven burden of brain and nervous system cancers across US
A new nationwide study has revealed striking differences in how brain and nervous system cancers affect Americans depending on where they live, as well as their age, sex and socioeconomic status, according to the study published in JAMA Neurology.
November 23, 2025 — Source

Health — Cancer — November 22nd, 2025

Experts launch digital hub to transform bowel cancer prevention and care
World-leading experts have launched an online platform to enable the public to shape the future of bowel cancer research and patient care.
November 22, 2025 — Source

Intranasal nanomedicine shows promise against glioblastoma
Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed a noninvasive approach to treat one of the most aggressive and deadly brain cancers. Their technology uses precisely engineered structures assembled from nano-size materials to deliver potent tumor-fighting medicine to the brain through nasal drops. The novel delivery method is less invasive than similar treatments in development and was shown in mice to effectively treat glioblastoma by boosting the brain's immune response.
November 22, 2025 — Source

New nasal nanodrops wipe out brain tumors in mice
A nasal-delivered nanotherapy turns silent glioblastoma tumors into immune-targeted ones—and destroys them in mice.
November 22, 2025 — Source or Source

Health — Cancer — November 21st, 2025

A drug already in trials may stop chemotherapy nerve damage
Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept their nerves healthier. A drug already being tested for cancer may help do the same in people. Early blood tests suggest it may even be possible to predict who will develop these symptoms before they happen.
November 21, 2025 — Source

After series of denials, his insurer approved doctor-recommended cancer care. It was too late.
For nearly three years, Eric Tennant endured chemotherapy infusions, rounds of radiation, biopsies, and hospitalizations that left him weak and depleted.
November 21, 2025 — Source or Source

AI can help cancer patients better understand CT reports
Medical reports written in technical terminology can pose challenges for patients. A team at the Technical University of Munich (TUM) has investigated how artificial intelligence can make CT findings easier to understand. In the study, reading time decreased, and patients rated the automatically simplified texts as more comprehensible and more helpful.
November 21, 2025 — Source

Cancer stole her voice. She used AI, curse words, and kids' books to get it back.
When doctors told her they had to remove her tongue and voice box to save her life from the cancer that had invaded her mouth, Sonya Sotinsky sat down with a microphone to record herself saying the things she would never again be able to say.
November 21, 2025 — Source or Source

CT colonography cost-effective for CRC screening in Black adults
Szu-Yu Zoe Kao, from Siemens Medical Solutions U.S. Inc., in Malvern, Pennsylvania, and colleagues examined the cost-effectiveness of CTC for CRC screening by race (Black and White) and gender in a microsimulation model. The model incorporated 2010 to 2019 U.S. data on disease progression and real-world screening adherence for colonoscopy and the fecal immunochemical test (FIT). Status quo (choice between colonoscopy and FIT), CTC every five years, colonoscopy every 10 years, annual FIT, and multitarget stool DNA test every three years were compared.
November 21, 2025 — Source

Diagnostics for pancreatic cancer can improve with the help of AI
Pancreatic cancer is the deadliest form of cancer worldwide, mainly because the disease is often discovered late. Symptoms associated with these tumors are often non-specific, so patients and doctors do not immediately suspect cancer. Moreover, these tumors are difficult to detect in the early stages on abdominal CT scans. Once the diagnosis is made, curative treatment is usually no longer possible. Only 10% of patients survive beyond five years.
November 21, 2025 — Source

Genetic events that can trigger leukemia in patients with a rare disorder deciphered
Two parallel and complementary studies conducted by the IDIBELL team led by Dr. Alessandra Giorgetti have succeeded in recreating models of GATA2 deficiency disease, a rare genetic disorder that affects fewer than 1 million people worldwide. Thanks to these new models developed by Dr. Giorgetti's team, we now have a clearer understanding of the molecular process by which the hematopoietic stem cells of these patients become cancerous.
November 21, 2025 — Source

Global collaboration accelerates progress toward eliminating cervical cancer
Cervical cancer will be the first human cancer eliminated through coordinated global action. A new special issue of Cancer Biology & Medicine brings together leading experts from around the world to examine progress, challenges, and innovations in prevention, screening, and treatment. From policy frameworks and epidemiological insights to digital health tools and therapeutic vaccines, the collection provides a timely resource for accelerating the World Health Organization's 2030 targets for cervical cancer elimination and advancing women's health equity worldwide.
November 21, 2025 — Source

Marine bacteria show potent antitumor effects against colorectal cancer
A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.
November 21, 2025 — Source

Marine bacterium shows powerful therapeutic effects against colorectal cancer
A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.
November 21, 2025 — Source

New study highlights key findings on lung cancer surveillance rates
Despite recommendations for posttreatment surveillance in lung cancer patients, there is wide variability in the follow-up care that lung cancer patients receive. A recent study, led by senior author Leah Backhus, MD, MPH, Professor of Cardiothoracic Surgery (Thoracic Surgery) in the Stanford Department of Cardiothoracic Surgery, offers new insights on patient care and lung cancer surveillance rates.
November 21, 2025 — Source

Protein droplets in the nucleus guard against cancer, researchers discover
Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a gene-regulating protein forms tiny liquid-like droplets inside the cell nucleus (the compartment that stores and manages DNA) to guard against cancer. Their study, published in Nature Communications, shows that these protein droplets act as control centers that keep tumor-suppressor genes switched on.
November 21, 2025 — Source

The Covid Contrarian Clubhouse Makes Its Mark on Trump's Washington
There are countless think tanks in the U.S. seeking to influence local, state, and national policy. A relatively new one is making its mark in President Donald Trump's Washington: the Texas-based Brownstone Institute.
November 21, 2025 — Source

Three times as many lung cancer deaths could be prevented with one simple step
Three times as many lung cancer deaths could be prevented if everyone eligible for screening got a chest CT scan, a new study says.
November 21, 2025 — Source

Understanding intrinsically disordered protein regions and their roles in cancer
Every function in a cell is associated with a particular protein or group of proteins, typically in a well-defined three-dimensional structure. However, intrinsically disordered regions of proteins defy this structure-function paradigm.
November 21, 2025 — Source

US Cancer Registries, Constrained by Trump Policies, To Recognize Only 'Male' or 'Female' Patients
The top authorities of U.S. cancer statistics will soon have to classify the sex of patients strictly as male, female, or unknown, a change scientists and advocates say will harm the health of transgender people, one of the nation's most marginalized populations.
November 21, 2025 — Source

US lung cancer screening fails most patients, according to study
In a study of nearly 1,000 consecutive patients treated for lung cancer at Northwestern Medicine, researchers discovered only 35% would have qualified for screening, according to the U.S. Preventive Services Task Force (USPSTF) screening criteria. The two-thirds of patients who would have been excluded were disproportionately women and never-smokers.
November 21, 2025 — Source

Health — Cancer — November 20th, 2025

A microRNA cocktail weakens brain tumors in preclinical trials
A patented RNA-based cocktail developed at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has emerged as a promising active agent against tumors of the central nervous system, such as glioblastoma.
November 20, 2025 — Source

Cancer cells have backup metabolic pathway to keep building DNA when blocked, study finds
The discovery could open the door to new treatments that starve tumors of their essential building blocks, said Issam Ben-Sahra, Ph.D., the Thomas D. Spies Professor of Genetic Metabolism and associate professor of Biochemistry and Molecular Genetics, who was senior author of the study.
November 20, 2025 — Source

Chronic hepatitis C linked to increased risk of pancreatic cancer
A Yale University study published in JAMA Network Open found chronic hepatitis C infection is linked to an 1.8-fold increased risk of pancreatic cancer.
November 20, 2025 — Source

Clinical tool helps predict which brain tumors will require treatment
A new study has shown that a clinical tool developed by the University of Liverpool and The Walton Center can accurately predict whether the most common type of brain tumor will grow or cause symptoms, helping doctors and patients make better-informed decisions about care.
November 20, 2025 — Source

Engineered immune cells target and destroy glioblastoma in animal models
With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer. Until now, all available treatments, including immunotherapy—which involves strengthening the immune system to fight cancer—have proved disappointing. CAR-T cells are genetically modified immune cells manufactured in the laboratory and designed to identify and destroy cancer cells.
November 20, 2025 — Source

French scientists probe mRNA's potential to fight cancer
Inside a lab in the French city of Orleans, scientists are testing out the limits of molecules in our body called messenger RNA—best known for being used in COVID-19 vaccines—in the hopes of finding a breakthrough treatment for a particularly deadly cancer.
November 20, 2025 — Source

Gene scissors in camouflage mode help in the search for cancer therapies
The immune system plays a crucial role in fighting tumors and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible—which is easier said than done.
November 20, 2025 — Source

Heat shock protein masks BRCA1 mutations, suggesting a new treatment path
Researchers from The University of Texas MD Anderson Cancer Center identified a new role for heat shock protein 90 (HSP90) in cancer predisposition and treatment resistance.
November 20, 2025 — Source

New therapeutic strategies show promise against a hard-to-treat prostate cancer
A new study has uncovered promising therapeutic strategies against one of the deadliest forms of prostate cancer.
November 20, 2025 — Source

Study suggests type 1 diabetes may significantly raise bladder cancer risk
People with type 1 diabetes (previously called juvenile diabetes) are 4.29 times more likely to develop bladder cancer, according to a systematic review and meta-analysis by researchers at the Keck School of Medicine of USC. The new analysis is the first to control for the effects of tobacco smoking, a factor that likely obscured the heightened risk in earlier studies.
November 20, 2025 — Source

Health — Cancer — November 14th, 2025

Cancer care crowdfunding increasingly common, but rarely successful
A growing number of desperate cancer survivors are turning to crowdfunding to help pay for their treatment and living expenses, a new study says.
November 14, 2025 — Source

Combination immunotherapy for rare cancers shows improved efficacy and survival rates
Combining nivolumab and ipilimumab in patients with advanced mismatch repair-deficient or microsatellite instability-high cancers resulted in a 63% objective response rate and 71% progression-free survival at six months, substantially exceeding outcomes seen with monotherapy. These findings support combination immunotherapy as a more effective option for rare, difficult-to-treat cancers.
November 14, 2025 — Source

Computational deep dive reveals hidden cancer drug targets and repurposing opportunities
"The kinds of small molecules representing many of our medicines are rarely found in nature, so they haven't evolved to carry out a specific task," said Sanju Sinha, Ph.D., an assistant professor in the Cancer Metabolism and Microenvironment Program at Sanford Burnham Prebys Medical Discovery Institute. "Sometimes the field looks at these drugs with tunnel vision in terms of them having a single target along with some side effects labeled as 'off-target effects."
November 14, 2025 — Source

How brain fluid flow predicts survival in glioblastoma
Glioblastoma—the most aggressive form of brain cancer—remains one of medicine's biggest challenges. Despite surgery, radiotherapy, and chemotherapy, most patients survive only about a year after diagnosis.
November 14, 2025 — Source

Deep learning system could transform skin cancer detection with near-perfect accuracy
Melanoma remains one of the hardest skin cancers to diagnose because it often mimics harmless moles or lesions. While most artificial intelligence (AI) tools rely on dermoscopic images alone, they often overlook crucial patient information (like age, gender, or where on the body the lesion appears) that can improve diagnostic accuracy. This highlights the importance of multimodal fusion models that can enable high precision diagnosis.
November 14, 2025 — Source

MD Anderson launches historic $2.5 billion campaign to end cancer
The University of Texas MD Anderson Cancer CenterUniversity of Texas MD Anderson Cancer Center today launches its historic $2.5 billion comprehensive philanthropic campaign, Only Possible Here, The Campaign to End Cancer. The campaign represents the largest fundraising effort in MD Anderson's 84-year history, bringing together philanthropic support from around the world to advance the institution's mission to end cancer. Initial donor support already has raised $1.9 billion toward the campaign goal.
November 14, 2025 — Source

Skin cancer cluster found in 15 Pennsylvania counties with or near farmland
Counties in Pennsylvania that contained or were near cultivated cropland had significantly higher melanoma rates compared to other regions, according to a new study led by scientists at Penn State.
November 14, 2025 — Source

Surgery after immunotherapy boosts survival for liver cancer patients
A new Cedars-Sinai Cancer study shows that patients with advanced liver cancer who receive immunotherapy to shrink their tumors have improved outcomes after liver transplant or tumor removal.
November 14, 2025 — Source

Traces of bacteria inside brain tumors may affect tumor behavior
Researchers at The University of Texas MD Anderson Cancer Center have uncovered unexpected traces of bacteria within brain tumors. This discovery offers new insights into the environment in which brain tumors grow and sets the stage for future studies seeking to improve treatment outcomes.
November 14, 2025 — Source

Transforming colorectal cancer research with patient-derived xenograft models
Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized treatment approaches. These models, created by transplanting fresh human tumor tissue into immunodeficient mice, faithfully replicate the genetic, histological, and molecular features of the original tumors. As such, they serve as invaluable resources in the study of tumor heterogeneity and in the development of precision oncology.
November 14, 2025 — Source

UK study exposes cancer care deficit for patients with learning disabilities
Individuals in England with learning disabilities face higher cancer risk, particularly before age 50, and experience lower rates of urgent investigation, later-stage diagnoses, and reduced access to treatment. Life expectancy after cancer diagnosis is significantly shorter, especially for those with severe disabilities or Down syndrome. Certain cancers, such as sarcoma and central nervous system cancers, are notably more common in this group.
November 14, 2025 — Source

Health — Cancer — November 13th, 2025

Extreme age protects against cancer in mouse study
Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led by Stanford University researchers. The discovery flies in the face of established dogma that holds that cancer risk increases with age, but it dovetails with what's seen in very elderly people, in whom cancer risk appears to either level off or even decline with age.
November 13, 2025 — Source

Gut bacterium may sabotage liver cancer immunotherapy, study suggests
A research team led by the Department of Clinical Oncology, Center of Cancer Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified a critical factor contributing to the failure of liver cancer immunotherapy. The study discovered that the gut bacterium Phocaeicola vulgatus can disrupt the immune system, leading to resistance to immunotherapy in some liver cancer patients.
November 13, 2025 — Source

Machine learning predicts drug response for personalized colorectal cancer treatment
A Singaporean research team has developed CAN-Scan (short for Cancer Scan), a next-generation precision oncology platform designed to "scan" the molecular features of each patient's cancer. Published in Cell Reports Medicine, CAN-Scan integrates patient-derived tumor models, multi-omics profiling, and machine learning to predict disease progression and therapeutic response, with the potential to personalize treatment for colorectal cancer (CRC) patients in the future.
November 13, 2025 — Source

New 'ultra-mild' sequencing method fixes long-standing flaws in cancer DNA methylation tests
UMBS-seq achieves both accuracy and gentleness, unlocking more reliable cancer biomarker detection. The method, which was initially developed by researchers at the University of Chicago, will be made commercially available to cancer diagnostic test developers by Ellis Bio early next year.
November 13, 2025 — Source

Single-cell study reveals how HPV shapes immune landscape in penile cancer
Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with a five-year survival rate near 50%. Around half of Penile squamous cell carcinoma (PSCC) cases are associated with persistent HPV infection, which triggers oncogenic transformation via viral oncoproteins E6 and E7. Interestingly, HPV-positive PSCC patients tend to have better survival and treatment responses compared to HPV-negative cases. However, the mechanisms behind this clinical advantage remain poorly understood.
November 13, 2025 — Source

What are the signs of a brain tumor?
Have you been having headaches that won't go away, confusion or changes in your senses? You may wonder if these are signs of a brain tumor.
November 13, 2025 — Source

Health — Cancer — November 9th, 2025

Protein linked to cancer found to play key role in wound healing
When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously wrong, from hard-to-treat cancers to severe inflammatory conditions.
November 9, 2025 — Source

Health — Cancer — November 8th, 2025

Nanovaccine shows great promise for treating HPV-related cancers
Therapeutic vaccine eliminated tumors, extended survival in lab setting.
November 8, 2025 — Source

Health — Cancer — November 7th, 2025

Bioengineered bone marrow model successfully used in leukemia research
Scientists at the University of Glasgow have successfully used the first bioengineered bone marrow model to carry out vital cancer research, offering new insights into potential therapies for the disease.
November 7, 2025 — Source

How colorectal cancer evades immunotherapy using a dual barrier
Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies—treatments that reactivate the immune system to attack tumor cells—have transformed the treatment of many types of cancer. However, most patients with metastatic colorectal cancer do not respond to these treatments.
November 7, 2025 — Source

Promising drug can inhibit aggressive breast cancer
Promising drug can inhibit aggressive breast cancer
November 7, 2025 — Source

Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer
Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden driven primarily by persistent high-risk HPV infection and genetic susceptibility.
November 7, 2025 — Source

Study reveals trends and future projections of cancer mortality in China
Cancer remains the second leading cause of death in China, accounting for nearly one-quarter of all deaths nationwide. Rapid socioeconomic change, environmental exposure, and an aging population have intensified the burden of cancer across the country. Although national programs in cancer prevention and early detection have improved survival rates, regional inequalities persist. Rural residents face limited access to medical care and lower screening coverage compared to urban populations.
November 7, 2025 — Source

Study reveals tumor defense mechanisms in colorectal cancer
Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies-treatments that reactivate the immune system to attack tumor cells-have transformed the treatment of many types of cancer. However, most patients with metastatic colorectal cancer do not respond to these treatments.
November 7, 2025 — Source

The hidden "Big Bang" that decides how bowel cancer grows
Bowel cancer's fate is sealed in a single "Big Bang" moment of immune escape, offering new hope for early, targeted treatments.
November 7, 2025 — Source

Health — Cancer — November 6th, 2025

American Cancer Society releases first-ever U.S. Tobacco Atlas
The American Cancer Society (ACS) announced the inaugural release of The U.S. Tobacco Atlas, a fact-based, digital scientific resource offering comprehensive data and insights on tobacco use, control policies, and their impact nationwide. The report notes that cigarette smoking among U.S. adults dropped from 42% in 1965 to 11% in 2023.
November 6, 2025 — Source

Q&A: Managing menopause after cancer
Menopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more intense. Treatments like chemotherapy, radiation, surgery, and/or endocrine therapy can trigger menopause or menopause-like symptoms, leaving patients wondering what's normal, what's manageable, and what's safe when it comes to treatment options.
November 6, 2025 — Source

Scanning nanoprobe microscope reveals the hidden flexibility of cancer cells
A new Nanoendoscopy-AFM technique enables direct, minimally invasive measurement of nuclear elasticity in living cancer cells, revealing that changes in nuclear stiffness are primarily determined by chromatin compaction rather than nuclear lamins. These mechanical properties correlate with disease progression and may serve as biomarkers for cancer diagnosis and prognosis.
November 6, 2025 — Source

Health — Cancer — November 5th, 2025

Certain p53 mutations may make tumors more vulnerable to immunotherapy
The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to cancer. But when p53 mutates, it can flip from protector to promoter of cancer.
November 5, 2025 — Source

Existing drug could reduce breast cancer risk in pre-menopausal women
Ulipristal acetate, a drug that blocks progesterone, reduced breast tissue density and the number of luminal progenitor cells in pre-menopausal women at high risk for breast cancer. Treatment also decreased collagen proteins, especially collagen 6, making breast tissue less favorable for cancer development. These findings suggest potential for ulipristal acetate in breast cancer prevention.
November 5, 2025 — Source

Experimental drug blocks key protein to trigger cancer cell self-destruction in lung tumors
NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.
November 5, 2025 — Source

How gray hair and cancer may be linked
Gray hair is an inevitable hallmark of aging. It's a visual reminder of the passing years and all the bodily changes that accompany it.
November 5, 2025 — Source

Macrophage 'bodyguard' disruptors may help overcome hormone-resistant breast cancer
In preclinical studies, researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have tested a new combination therapy for hormone-resistant, estrogen receptor-positive (ER+) breast cancer and were able to shrink tumors, reduce the number of cancer stem cells and reprogram the immune environment to be less supportive of cancer growth.
November 5, 2025 — Source

Most Americans don't know alcohol can cause cancer
Most U.S. adults don't realize alcohol raises cancer risk, and drinkers themselves are the least aware. Scientists say targeting these misbeliefs could significantly reduce alcohol-related cancer deaths.
November 5, 2025 — Source

Physical activity levels linked to risk for digestive system cancers
Yiwen Zhang, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues examined the association between physical activity and DSC risk and mortality with a focus on the optimal amount and long-term consistency. The study included data from the Health Professionals Follow-Up Study, the Nurses' Health Study, and the Nurses' Health Study II.
November 5, 2025 — Source

Radiotherapy after mastectomy can be avoided, study finds
Radiotherapy can be safely omitted as a treatment for many breast cancer patients who have had a mastectomy and are taking anti-cancer drugs, a study shows.
November 5, 2025 — Source

Study identifies key genes linked to aggressive prostate cancer in people of African descent
Variants in five genes—ATM, BRCA2, CHEK2, HOXB13, and PALB2—are strongly associated with aggressive and metastatic prostate cancer in men of African descent. Combining these genetic markers with polygenic risk scores and family history enables more precise risk assessment, potentially improving personalized screening and reducing disparities in prostate cancer outcomes.
November 5, 2025 — Source

The case for a cancer warning on processed meat
A group of scientists in the UK recently demanded that bacon and ham products carry health warnings similar to those on cigarettes.
November 5, 2025 — Source

Triggering cell death in metastatic melanoma may pave the way for new cancer treatments
Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a surprising metabolic dependency that could open the door to a new class of cancer treatments, according to a new study led by Harvard T.H. Chan School of Public Health.
November 5, 2025 — Source

Ultrasound-activated Nanoparticles Kill Liver Cancer and Activate Immune System
A new ultrasound-guided nanotherapy wipes out liver tumors while training the immune system to keep them from coming back.
November 5, 2025 — Source

USC-led study advances understanding of prostate cancer genetics in Black men
New prostate cancer research from an international team led by the Center for Genetic Epidemiology at the Keck School of Medicine of USC has yielded discoveries that could improve screening and treatment for patients of African ancestry. The scientists identified variants of five genes linked in this population to aggressive disease or to cancer that spreads, or metastasizes, to other organs. The study also found a wide range of risk among participants. By combining data on the five specific genes with other methods of determining risk, the researchers introduced a method that could help identify those most likely to face deadlier forms of the disease.
November 5, 2025 — Source

Why cancer immunotherapy isn't effective for everyone
A study led by Andre Veillette, a researcher at the Montreal Clinical Research Institute (IRCM) and a professor in the Faculty of Medicine at University of Montreal, sheds new light on the complexity of the immune system and its role in cancer treatment.
November 5, 2025 — Source

Health — Cancer — October 31st, 2025

AI tool makes detection of skin cancer more accurate
Researchers at Fox Chase Cancer Center, Temple University's College of Engineering, and the Lewis Katz School of Medicine at Temple University have developed a new method that enhances the ability of artificial intelligence models to detect and diagnose skin cancer in individuals with darker skin.
October 31, 2025 — Source

Better Treatments Buoy Multiple-Myeloma Patients, Bound by Research Cuts and Racial Disparities
For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination. Her primary care physician had ruled out diabetes before finally chalking up her ailments to getting older.
October 31, 2025 — Source

Could a cancer vaccine developed long ago hold the key to long-term survival in breast cancer?
A small group of women with advanced breast cancer received a vaccine via a clinical trial more than 20 years ago. Today, they're all still alive. Scientists say that kind of long-term survival is almost unheard of for patients with metastatic breast cancer, and it's what caught the attention of researchers now.
October 31, 2025 — Source

DNA copy-number changes help melanoma develop resistance to immunotherapy, study finds
The team found that relapsing melanoma tumors often acquire genomic DNA copy-number variants, which delete or amplify sections of DNA. These variants frequently affect genes that control the cancer cells' ability to self-destruct in response to damage caused by immune attack. The cumulative effect of copy-number changes, often involving multiple cell-death genes, allows cancer cells to survive immune attacks, leading to tumors relapsing or regrowing months or years after the initial therapy-induced tumor shrinkage.
October 31, 2025 — Source

FDA says drug makers have recalled a blood pressure medicine tainted with a cancer-causing chemical
The U.S. Food and Drug Administration says drug makers have recalled more than a half-million bottles of the blood pressure medication prazosin hydrochloride over concerns it may include a cancer-causing chemical.
October 31, 2025 — Source

Researchers develop nanoparticles that stimulate the immune system to attack ovarian tumors
Targeted particles carrying the cytokine IL-12 can jump-start T cells, allowing them to clear tumors while avoiding side effects.
October 31, 2025 — Source

SNA-Based Drug Slow Cancer Progression 59-Fold in Animal Models
By reengineering a decades-old chemotherapy drug into a DNA-wrapped nanostructure, Northwestern University researchers have turned a poorly soluble medicine into a precision cancer killer. Their findings could redefine how chemotherapy treatments occur in the future.
October 31, 2025 — Source

Studies identify complementary approaches to overcome drug resistance in KRAS G12C--mutant lung cancer
Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C--mutant non-small cell lung cancer.
October 31, 2025 — Source

Targeted nanoparticles can jumpstart T cells, allowing them to attack ovarian tumors while avoiding side effects
Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to treating many types of cancer. However, it doesn't work well for some tumors, including ovarian cancer.
October 31, 2025 — Source

Health — Cancer — October 30th, 2025

A promising molecule against chemotherapy-induced neuropathies
Currently incurable, peripheral neuropathies are common neurological complications of chemotherapy, causing persistent pain, tingling and burning sensations in the feet and hands, sometimes even after treatment has ended. In the hope of offering a therapeutic option to affected patients, a research team led by a CNRS researcher has identified a molecule capable of preventing the onset of such side effects.
October 30, 2025 — Source

Americans have widespread misbeliefs about the cancer risks of alcohol, study finds
Despite clear evidence linking alcohol use to increased cancer risks, public awareness of this connection remains low in the U.S., according to new research from The University of Texas MD Anderson Cancer Center. Researchers found that more than half of American adults (52.9%) did not know alcohol affects cancer risk.
October 30, 2025 — Source

Breast cancer risk varies between different hormonal contraceptives, research reveals
Some common hormonal contraceptives are linked to a slightly higher risk of breast cancer than others. This is shown by a Swedish study from Uppsala University, in which researchers followed more than two million women and teenage girls in Sweden to identify how different hormonal contraceptives affect the risk of breast cancer.
October 30, 2025 — Source

Dual studies uncover complementary strategies to overcome resistance to KRAS G12C inhibitors in lung cancer
KRAS G12C-mutant non-small cell lung cancers often develop resistance to KRAS G12C inhibitors by reactivating RAS signaling or adapting through alternative mechanisms. Next-generation RAS(ON) inhibitors can block both mutant and wild-type RAS, while CDK12/13 inhibitors exploit resistance-associated vulnerabilities in DNA repair and mitosis. Combined, these strategies delay or prevent resistance and extend treatment response.
October 30, 2025 — Source

Early clinical trial tests immune-boosting therapy before prostate cancer surgery
A small, early clinical trial led by the Icahn School of Medicine at Mount Sinai and collaborators has shown that directly injecting an immune-activating compound into prostate tumors before surgery appears safe and may help the immune system recognize and attack cancer cells.
October 30, 2025 — Source

Experimental cancer drug shows exceptional tumor-fighting potential
A research team has developed a new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies. Published in the journal Molecular Cancer, the study introduces a highly promising strategy for tackling drug-resistant cancers. The team was led by the Medical University of Vienna, the HUN-REN Research Center for Natural Sciences and the Eötvös Loránd University in Budapest.
October 30, 2025 — Source

From antibiotics to antimalarials: How repurposed drugs might keep cancer from returning
Many cancer survivors live with the worry that their cancer might come back. This "recurrence" occurs when cancer cells hide somewhere in the body—like in the bone marrow—and start growing again, sometimes years later. Scientists have been trying to understand how to stop these cells from reactivating and causing cancer to spread.
October 30, 2025 — Source

New method yields up to twice as many therapeutic myogenic cells as previous protocols
If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.
October 30, 2025 — Source

Public awareness about the effect of alcohol on cancer risk remains low in the U.S.
Despite clear evidence linking alcohol use to increased cancer risks, public awareness of this connection remains low in the U.S., according to new research from The University of Texas MD Anderson Cancer Center. Researchers found that more than half of American adults (52.9%) did not know alcohol affects cancer risk.
October 30, 2025 — Source

Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance
One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.
October 30, 2025 — Source

Some hormonal contraceptives linked to higher risk of breast cancer
Some common hormonal contraceptives are linked to a slightly higher risk of breast cancer than others. This is shown by a new Swedish study from Uppsala University, in which researchers followed more than two million women and teenage girls in Sweden to identify how different hormonal contraceptives affect the risk of breast cancer.
October 30, 2025 — Source

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment
Gastric cancer remains a major global health challenge, characterized by high mortality and limited therapeutic efficacy, especially in advanced stages. With conventional treatments like surgery and chemotherapy often yielding suboptimal outcomes and significant side effects, there is an urgent need for safer and more effective alternatives. Scleromitrion diffusum (Willd.), a traditional Chinese medicine (TCM) herb with a long history of use in oncology, has shown promising clinical potential against gastric cancer.
October 30, 2025 — Source

Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K--AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas. While multimodal therapies have improved outcomes for low- and intermediate-risk patients, high-risk or metastatic cases still suffer poor survival rates below 30%. Existing treatments are often toxic and limited by drug resistance. Thiostrepton (TST), first isolated in the 1950s from Streptomyces azureus, has recently emerged as a promising anticancer agent due to its unique ability to inhibit tumor-related transcription factors and signaling pathways.
October 30, 2025 — Source

Transcription factor drives chemotherapy resistance in ovarian cancer
Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and chemotherapy resistance in ovarian cancer cells, findings that may inform new targeted treatment approaches that inhibit this process and improve patient outcomes, according to a recent study published in the Journal of Clinical Investigation.
October 30, 2025 — Source

Health — Cancer — October 25th, 2025

Scientists just found a surprising link between gray hair and cancer
Hair graying and melanoma emerge as two divergent fates of stressed stem cells—protection or peril.
October 25, 2025 — Source

Health — Cancer — October 24th, 2025

Common jobs held by immigrant women may put them at increased risk of breast cancer
Many immigrant women in the U.S. work in jobs that may expose them to chemicals linked to breast cancer, according to a new study led by Silent Spring Institute. The study is among the first to examine how job-related chemical exposures may contribute to breast cancer risk among foreign-born workers, especially in jobs with fewer health and safety protections.
October 24, 2025 — Source

Living tumor-on-a-chip exposes how cancers block immune attacks
For a little over two decades, chimeric antigen receptor (CAR) T cell therapy has emerged as a powerful new way to treat cancer. By extracting patients' T cells, re-engineering them to recognize tumor antigens, and infusing them back into the body, physicians have achieved effective treatments for leukemia and lymphoma cancers.
October 24, 2025 — Source

Medicaid expansion tied to smaller declines in early-stage cancer detection
Xuesong Han, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined the association of Medicaid expansion and changes in cancer stage at diagnosis during the COVID-19 pandemic using data for 1,844,515 individuals aged 18 to 64 years newly diagnosed with cancer in 2018 to 2022 from the National Cancer Database. The changes in proportions of early-stage cancer diagnoses were compared in Medicaid expansion versus nonexpansion states using a difference-in-differences (DD) approach.
October 24, 2025 — Source

Study shows protective effect of Medicaid expansion on early-stage cancer diagnosis
The COVID-19 pandemic disrupted health care, including cancer screening and diagnosis, especially for medically underserved populations, leading to substantial underdiagnosis of early-stage cancers in 2020. In a new study led by the American Cancer Society (ACS), scientists found that Medicaid expansion was associated with smaller declines in early-stage cancer detection among adults during the pandemic.
October 24, 2025 — Source

Toward rapid and comprehensive genetic diagnosis of pediatric cancer through adaptive sequencing
What if a single test could simultaneously contribute to the diagnosis, characterization, and treatment guidance of childhood cancer—while helping avoid toxic or potentially unnecessary treatments?
October 24, 2025 — Source

Health — Cancer — October 20th, 2025

AI system delivers comprehensive cancer diagnosis
The Hong Kong University of Science and Technology (HKUST) today launched SmartPath, a comprehensive artificial intelligence (AI) system designed to transform the entire pathology workflow for cancer care.
October 20, 2025 — Source

Are cancer surgeries removing the body's secret weapon against cancer?
New research reveals that lymph nodes, often removed during cancer surgery to prevent tumor spread, may actually be crucial for successful treatment.
October 20, 2025 — Source

Colon cancer DNA may guide tailored post-surgery care
Circulating tumor DNA (ctDNA) testing after surgery in Stage 3 colon cancer enables risk-based adjustment of chemotherapy. ctDNA-negative patients received less chemotherapy, resulting in fewer side effects and similar recurrence-free survival compared to standard care. ctDNA-positive patients had higher recurrence rates despite intensified therapy, indicating a need for new strategies in this group.
October 20, 2025 — Source

Combination of immunotherapy and targeted therapy boosts colorectal cancer survival, clinical trial finds
A new study led by UCLA investigators found that combining zanzalintinib, a targeted therapy drug, and atezolizumab, an immune checkpoint inhibitor, helped patients with metastatic colorectal cancer, the second most common cause of cancer death in the U.S., live longer and control their disease better than with the standard treatment drug regorafenib.
October 20, 2025 — Source

Guidance on the safe use of large language models in oncology practice
The ESMO Guidance on the Use of Large Language Models in Clinical Practice (ELCAP) provides structured recommendations for integrating AI language models into oncology. ELCAP outlines three categories: patient-facing, clinician-facing, and institutional systems, each with specific safety, validation, and oversight requirements. Emphasis is placed on human supervision, data quality, transparency, and robust governance.
October 20, 2025 — Source

Immune-altering drug suppresses tumor-protecting cells and enhances stomach cancer treatment
A modified, long-lasting TFF2-albumin protein suppresses immunosuppressive neutrophils in gastric tumors by modulating CXCR4 activity, enhancing immune recognition and response against cancer. Combined with standard therapies, this approach improves tumor reduction and survival in animal models, suggesting potential for broader application in cancer and immune-related diseases.
October 20, 2025 — Source

New generation of antibody-drug conjugates shows promise in early-stage HER2-positive breast cancer
Trastuzumab deruxtecan (T-DXd), a new-generation antibody-drug conjugate, significantly improves invasive disease-free survival and pathological complete response rates compared to current standard therapies in early-stage HER2-positive breast cancer, with a favorable safety profile and reduced cardiac toxicity. These findings support T-DXd as a new standard of care in both pre- and post-surgical settings.
October 20, 2025 — Source

Obesity-related cancer rising among both younger and older adults worldwide, study finds
A surveillance study compared international cancer incidence trends of 13 cancer types in younger and older adults.
October 20, 2025 — Source

Oral drug demonstrates promising anti-tumor activity in patients with advanced lung cancer
Sevabertinib, an oral tyrosine kinase inhibitor targeting HER2 mutations, induced tumor reduction in over 70% of patients with advanced HER2-mutant non-small cell lung cancer, including those previously treated with HER2-targeted therapies. The drug showed a manageable safety profile, with diarrhea as the most common side effect and no cases of interstitial lung disease.
October 20, 2025 — Source

Precision reprogramming: How AI tricks cancer's toughest cells
Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells—hard-to-find cells that help cancers spread, come back after treatment and resist therapy. The new approach, which the researchers tested in colon cancer, leveraged artificial intelligence (AI) to identify treatments that can reprogram cancer stem cells, ultimately triggering them to self-destruct.
October 20, 2025 — Source

Researchers find new way to cut cancer's lipid lifeline
Cancer thrives by hijacking the body's own basic survival systems, making it hard to attack tumors without collateral damage and side effects. Now, researchers at Cornell's Weill Institute for Cell and Molecular Biology have discovered what may be a less invasive strategy that shows promise as a potential therapeutic pathway.
October 20, 2025 — Source

Scientists create LED light that kills cancer cells without harming healthy ones
A new light-driven cancer therapy uses LEDs and tin nanoflakes to kill tumors safely and affordably. Developed by teams in Texas and Portugal, it eliminates up to 92% of skin cancer cells without harming healthy ones.
October 20, 2025 — Source

Scientists find immune drug that could halt skin cancer's deadly spread
Researchers found that pembrolizumab, an immune-activating cancer drug, lowered the risk of distant metastases in patients with Merkel cell carcinoma after surgery. Though recurrence rates overall weren't significantly changed, the results hint at a meaningful benefit in preventing cancer spread. The nationwide trial, one of the largest of its kind, underscores the promise of immunotherapy for rare, aggressive cancers.
October 20, 2025 — Source

SGLT2 inhibitors may slow nodule growth in pulmonary malignancies
In patients with diabetes and early-stage pulmonary malignancies, SGLT2 inhibitors are associated with reduced lung nodule growth (13.8% versus 25.7%) and fewer surgical interventions (5.5% vs 11.9%; hazard ratio 0.15) compared to alternative antidiabetic medications. Treating 15.6 patients with SGLT2 inhibitors prevents one surgical intervention over 10 years.
October 20, 2025 — Source

Survivors of high-risk neuroblastoma face substantial late effects of modern therapies
Within the last two decades, multiple stem cell transplants and immunotherapy have been added to intensive chemotherapy as the standard of care for high-risk neuroblastoma, drastically improving survival of this childhood cancer.
October 20, 2025 — Source

Targeted immunotherapy combination offers hope to older adults with leukemia
Researchers from the Alliance for Clinical Trials in Oncology have found that two targeted immunotherapy drugs lead to high remission rates and long survival with reasonable side effects for older patients with a tough-to-treat form of leukemia.
October 20, 2025 — Source

This common vitamin could cut your skin cancer risk in half
Vitamin B3 may be the simple, over-the-counter secret to cutting future skin cancer risk.
October 20, 2025 — Source

Health — Cancer — October 17th, 2025

Automated algorithm can detect cancer in blood samples in as little as 10 minutes
An AI algorithm named RED can rapidly detect rare cancer cells in blood samples within 10 minutes, automating a process that previously required hours of manual review. RED identifies unusual cell patterns without prior knowledge of cancer cell features, achieving detection rates of 99% for epithelial and 97% for endothelial cells, and reducing data volume by 10³-fold.
October 17, 2025 — Source

Collaboration leads to drug candidate for a hard-to-treat type of lung cancer
Sevabertinib, a reversible HER2 inhibitor, shows potential for treating non-small cell lung cancers with ERBB2 (HER2) exon 20 insertion mutations, which affect 2--4% of patients. Preclinical models and early clinical data indicate tumor shrinkage and selective targeting of mutated HER2, with minimal impact on normal EGFR. The drug is under FDA Priority Review.
October 17, 2025 — Source

'Craters' on surface of melanoma cells mark tumor-killing hotspots, study reveals
Distinct crater-like structures on melanoma cell surfaces act as immune hubs where CD8+ T cells aggregate and mediate tumor killing. These CRATERs expand following immune stimulation and are present in both melanoma and other solid tumors, suggesting their potential as markers for immunotherapy efficacy and treatment monitoring
October 17, 2025 — Source

Dense breasts: What it means and what women can do about screening
About half of women over 40 have dense breasts, which increases breast cancer risk and reduces mammogram sensitivity to as low as 25--30%. Since 2024, U.S. mammography centers must inform women of their breast density. Supplemental screening methods such as ultrasound, contrast-enhanced mammography, or MRI may be considered, depending on individual risk factors and insurance coverage.
October 17, 2025 — Source

Leukemia cells evade treatment by reshaping their mitochondria, researchers discover
Leukemia cells develop resistance to venetoclax by increasing OPA1 protein, which alters mitochondrial cristae to prevent apoptosis. Inhibiting OPA1 in mouse models restores drug sensitivity, prolongs survival, and does not harm normal blood cells. This approach may offer a new strategy for overcoming resistance in acute myeloid leukemia and other cancers.
October 17, 2025 — Source

Osimertinib plus chemotherapy improves survival in EGFR-mutated lung cancer
Treatment with osimertinib plus a platinum--pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed EGFR-mutated advanced non-small cell lung cancer (NSCLC) compared to osimertinib alone. The finding is based on an analysis of the complete data from the phase 3 global FLAURA2 study, co-led by researchers from Dana-Farber Cancer Institute and Gustave Roussy (Grand Paris, Villejuif, France). Median overall survival was 47.5 months in the osimertinib plus platinum--pemetrexed group versus 37.6 months in the osimertinib monotherapy group.
October 17, 2025 — Source

Samsung and GRAIL Announce Strategic Collaboration To Bring GRAIL's Galleri® Multi-Cancer Early Detection Test to Asia
Samsung C&T (SCT), Samsung Electronics (SEC), and GRAIL, Inc. (Nasdaq: GRAL), today announced they have signed a binding Letter of Intent for a strategic collaboration to bring GRAIL's GalleriⓇ multi-cancer early detection (MCED) test to key Asian markets. SCT and SEC have also agreed to invest $110 million into GRAIL, a healthcare company whose mission is to detect cancer early when it can be cured, at a price of $70.05 per share of common stock.
October 17, 2025 — Source

Supercharging immune cells to fight drug resistant bowel cancer
Engineered γδT cells expressing stIL-15 and a B7-H3 antibody exhibit prolonged survival and dual cytotoxic mechanisms (AIC and ADCC), enabling effective killing of drug-resistant, slow-growing bowel cancer cells in organoid models. These cells outperform regular γδT cells and may offer a promising immunotherapy approach for solid tumors.
October 17, 2025 — Source

Health — Cancer — October 15th, 2025

Checkpoint inhibitor promotes tissue repair, offering hope for chronic wound treatment
The immune checkpoint inhibitor TIGIT promotes tissue repair by inducing a growth factor in immune cells, which activates repair mechanisms following viral infection. Mice lacking TIGIT experience increased tissue damage, highlighting its protective role. These findings suggest potential therapeutic applications for chronic wounds and fibrosis by targeting TIGIT-mediated pathways.
October 15, 2025 — Source

Combination therapy shows promising results in patients with rare subtype of non-Hodgkin lymphoma
Bottom line: Combining an epigenetic therapy with an anti-PD-1 antibody, which uses the body's natural response to viral infections, showed promising results in patients with relapsed or refractory natural killer/T-cell lymphoma (R/R NKTL), a rare and aggressive cancer with limited treatment options.
October 15, 2025 — Source

Developing a green thumb while young can prevent cancer, study finds
Helping children develop a green thumb could have lifelong health benefits, including preventing cancer, according to new work from a University of Alberta public health researcher.
October 15, 2025 — Source

Fruit fly study reveals genetic targets for rare childhood brain cancer treatment
Using fruit flies, University of Wisconsin--Madison researchers have developed a new model for investigating the genetic drivers of a rare but aggressive brain tumor in children. The work has already identified potential treatment targets for the deadly cancer that has previously had few therapeutic options.
October 15, 2025 — Source

How to double lung cancer screening rates: Multidisciplinary program reaches over 70% screening rate
Lung cancer screening might be the best-kept secret in health care today. Only about 16% of those who are eligible in the U.S. get screened for lung cancer, but a study appearing in NEJM Catalyst provides a roadmap for how health systems can improve those numbers. The study details how the UR Medicine primary care network reached a nearly 72% lung cancer screening rate.
October 15, 2025 — Source

New research aims to develop targeted therapy for hard-to-treat osteosarcoma
For children and young adults diagnosed with osteosarcoma, a common type of bone cancer for that age group, the odds of survival can be devastatingly low (20-30%) when the disease spreads to the lungs.
October 15, 2025 — Source

New research identifies more accurate way of predicting which blood cancer patients will relapse early
A study carried out by a team of researchers from The Institute of Cancer Research, London, found that combining two types of genetic tests gives doctors a much better chance of identifying multiple myeloma patients who are at risk of early relapse.
October 15, 2025 — Source

Scientists identify markers of key stem cell populations driving colorectal cancer formation
Distinct stem cell populations marked by NOX1 and NPY1R proteins drive colorectal cancer formation in specific colon regions. These markers enable the development of region-specific cancer models, improving understanding of tumor origins and regional differences in disease behavior. The findings support the advancement of targeted diagnostics and therapies for colorectal cancer.
October 15, 2025 — Source

Study identifies new approach to protect the brain during radiation therapy
Targeted inhibition of the complement protein C5a and its receptor C5aR1 in the brain protects against cognitive decline caused by cranial radiation therapy, without reducing the therapy's effectiveness against cancer. The orally available inhibitor PMX205, which crosses the blood-brain barrier and is safe in humans, shows promise for preserving cognitive function in brain cancer survivors.
October 15, 2025 — Source

Study links obesity-driven fatty acids to breast cancer, warns against high-fat diets like keto
A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that promote tumor growth. Their research, conducted in preclinical mouse models, suggests that breast cancer patients and survivors with obesity could benefit from lipid-lowering therapies—and that they should avoid high-fat weight loss regimens like ketogenic diets.
October 15, 2025 — Source

Health — Cancer — October 13th, 2025

Bioengineering breathes new life into failed cancer treatment
Many advanced cancers develop resistance to treatment and become highly aggressive, often leaving patients with limited treatment options. In some cancers, including lung, pancreatic and prostate tumors, a key driver of treatment resistance and metastasis is a protein called integrin αv&beta3, which is absent in normal tissues but enriched in aggressive tumors.
October 13, 2025 — Source

Bridging innovation and equity to end cervical cancer worldwide
Each year, more than 340,000 women die from cervical cancer, with the majority of deaths occurring in low- and middle-income countries. Despite being highly preventable through vaccination and early detection, the disease remains the fourth most common cancer among women. In 2020, the World Health Organization (WHO) launched the Global Strategy to Accelerate the Elimination of Cervical Cancer, setting ambitious "90-70-90" targets for vaccination, screening, and treatment by 2030. Yet vast inequities in health resources, infrastructure, and implementation capacity threaten progress. Addressing these challenges requires not only scientific advances but also strong policy alignment and international cooperation.
October 13, 2025 — Source

'Google Maps' approach provides cell-by-cell tumor mapping for more personalized lung cancer treatment
Researchers have developed a way to predict how lung cancer cells will respond to different therapies, allowing people with the most common form of lung cancer to receive more effective individualized treatment.
October 13, 2025 — Source

Owlstone Medical wins up to $49.1 million award from ARPA-H to develop at-home multi-cancer-early detection tests
Owlstone Medical ("Owlstone"), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced that it has won an award of up to $49.1 million from the Advanced Research Projects Agency for Health (ARPA-H) for the Platform Optimizing SynBio for Early Intervention and Detection in Oncology (POSEIDON) program. POSEIDON aims to develop first-in-class synthetic-sensor based Multi-Cancer-Early Detection (MCED) tests for Stage I detection of 30+ solid tumors using only breath and urine samples that can be performed in the home and are available over the counter.
October 13, 2025 — Source

Study Delivers Cancer Drugs Directly to the Tumor Nucleus
A new peptide-based nanotube treatment sneaks chemo into drug-resistant cancer cells, providing a unique workaround to one of oncology's toughest hurdles.
October 13, 2025 — Source

Study offers new models for understanding the causes of chemo brain
Also called "brain fog," this mix of cognitive issues - memory problems, struggling to find words, an inability to concentrate - affects up to three-in-four cancer patients, according to multiple studies. For many, the effects last years beyond cancer treatment.
October 13, 2025 — Source

Targeting aggressive childhood leukemia with nanobody PROTACs
Scientists at the University of Duisburg-Essen are researching new therapies for aggressive forms of childhood leukemia. For the first time, their approach tries to distinguish between two subtypes using so-called nanobody PROTACs. These attack diseased tissue while sparing healthy cells. The Jose Carreras Leukaemia Foundation is supporting the project, led by Prof. Dr. Shirley Knauer and Dr. Mike Blueggel from the Faculty of Biology, with 143,740 euros for two years.
October 13, 2025 — Source

Targeting enzymes to weaken cancer cells could supercharge prostate cancer treatment
An international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men.
October 13, 2025 — Source

This experimental "super vaccine" stopped cancer cold in the lab
A next-gen nanoparticle vaccine shows stunning cancer prevention and immunity in mice.
October 13, 2025 — Source

Vitamin B3 supplement may reduce your risk of skin cancer
Nicotinamide, a form of vitamin B3, taken at 500 mg twice daily, is associated with a 14% reduction in new skin cancer risk, with up to a 54% decrease when started soon after a first diagnosis. The effect is strongest for squamous cell carcinoma and diminishes if begun after multiple recurrences. Nicotinamide is safe, inexpensive, and may complement existing prevention strategies.
October 13, 2025 — Source

Health — Cancer — October 10th, 2025

AI-supported cervical cancer screening tested in Kenya and Tanzania
AI can be used to detect cervical cancer in women in resource-limited parts of the world. However, for this method to work, investments are needed in health care staff, reliable supply chains and trust in these communities. This has been shown in a new study from Uppsala University, Karolinska Institutet and the University of Helsinki, where researchers tested an AI-supported diagnostic method at rural hospitals in Kenya and Tanzania.
October 10, 2025 — Source

Blood cancer: Scientists reprogram cancer cell death to trigger immune system
The aim of immunotherapy strategies is to leverage cells in the patient's own immune system to destroy tumor cells. Using a preclinical model, scientists from the Institut Pasteur and Inserm successfully stimulated an effective anti-tumor immune response by reprogramming the death of malignant B cells. They demonstrated an effective triple-therapy approach for treating forms of blood cancer such as certain lymphomas and leukemias which affect B cells.
October 10, 2025 — Source

Engineered stem cells yield millions of tumor-fighting natural killer cells at reduced cost
Chinese researchers have developed a novel method to efficiently engineer natural killer (NK) cells for cancer immunotherapy. NK cells are central to early antiviral and anticancer defense—among other immune system roles—making them well-suited for cancer immunotherapy. For example, chimeric antigen receptor (CAR)-NK therapy involves adding a lab-built receptor (a CAR) to an NK cell, enabling it to recognize a specific antigen on a cancer cell and attack it.
October 10, 2025 — Source

Enhanced multi-omics tool illuminates cancer progression
GoT-Multi, an advanced single-cell multi-omics tool, enables simultaneous detection of multiple gene mutations and gene activity in individual cancer cells, including those from formalin-fixed, paraffin-embedded samples. This technology allows high-throughput analysis, revealing detailed mechanisms of cancer progression and therapy resistance, and may inform new therapeutic approaches.
October 10, 2025 — Source

LED light blasts cancer cells and spares healthy ones
A new cancer treatment combines LED light and tiny tin flakes to neutralize cancer cells while shielding healthy cells and avoiding the painful side effects associated with chemotherapy and other treatments.
October 10, 2025 — Source

New GoT-Multi technology reveals how cancers evolve and resist treatment
A new tool developed by Weill Cornell Medicine and the University of Adelaide investigators has enhanced the ability to track multiple gene mutations while simultaneously recording gene activity in individual cancer cells. The technology, which can now use diverse types of pathology samples and quickly process large numbers of cells, has enabled the investigators to glean new insights into how cancers evolve toward greater aggressiveness and therapy resistance.
October 10, 2025 — Source

Peptide nanotubes show promise for overcoming chemotherapy resistance
Cyclic peptide nanotubes can selectively deliver doxorubicin into the nuclei of resistant tumor cells by exploiting their affinity for anionic cancer cell membranes. This approach bypasses common drug resistance mechanisms, maintains antitumor efficacy, and offers a promising strategy for enhancing chemotherapy effectiveness against hard-to-treat cancers.
October 10, 2025 — Source

Top 10 questions about breast cancer answered
Breast cancer receives much attention during October's awareness month. Although sightings of pink ribbons and breast cancer-related information increase during the month, it's crucial to keep screenings and clinical breast exams at the forefront of preventive care year-round.
October 10, 2025 — Source

Health — Cancer — October 8th, 2025

Cancer outcomes in Australia are improving overall
Cancer survival rates have improved over three decades as cancer mortality rates decline, according to new data published today by the Australian Institute of Health and Welfare (AIHW).
October 8, 2025 — Source

Engineered CAR-NK cells could evade immune rejection and target cancer more effectively
One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.
October 8, 2025 — Source or Source

Engineered Salmonella therapy delivers immune payloads to combat cancer
A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."
October 8, 2025 — Source

Immune cell homing hydrogel-based platform captures dendritic cells to process mRNA from cancer vaccines
A research team led by Cancer Center at Illinois (CCIL) member Hua Wang has published new research detailing a new mRNA cancer vaccine platform. The study introduces an immune cell homing hydrogel-based platform designed to overcome one of the biggest hurdles in conventional mRNA cancer vaccines: the extremely low efficiency of antigen-encoded mRNAs being processed by the right type of immune cells in the body.
October 8, 2025 — Source

Improved five-year cancer survival observed after Medicaid expansion
Bottom Line: Adoption of Medicaid expansion in U.S. states appeared to improve both five-year cause-specific and overall survival in cancer patients.
October 8, 2025 — Source

Improved genetic tool reveals hidden mutations that can drive cancer
Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide insights into the earliest steps of cancer development and the role of mutations in healthy tissue.
October 8, 2025 — Source

Ireland launches next phase of national precision oncology program
Today (8th October), Ireland's Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD, launched Phase 2 of the country's leading and largest ever cancer research program, Precision Oncology Ireland (POI).
October 8, 2025 — Source

Kennesaw State researcher explores how hormones influence cancer development
Joanna Wardwell-Ozgo figures to work backward when determining the causes of cancer.
October 8, 2025 — Source

Medicaid cuts could be dangerous for cancer survivors
Earlier in 2025, the Trump administration approved $900 billion in sweeping cuts to Medicaid, the publicly funded health program for low-income families and people with disabilities. Democrats are now demanding that Republicans address some of their concerns about patients who rely on safety-net health care programs, which has led to a deadlock in Washington over a federal spending plan and the ongoing government shutdown.
October 8, 2025 — Source

Nanomedicine emerges as a key tool to boost cancer immunotherapy
Scientists at the Fralin Biomedical Research Institute at VTC and their collaborators are exploring emerging trends in cancer immunotherapy, with back-to-back review articles published in Nature Cancer and Trends in Cancer that look at how nanotechnology could reprogram the immune system and help overcome tumors' defenses.
October 8, 2025 — Source

Novel immunotherapy combination destroys colorectal liver metastases
Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver. Despite progress in surgical therapies aimed at eradicating the cancer, many of these patients will have tumor recurrence in the liver.
October 8, 2025 — Source

Refined DNA sequencing tool reveals hidden mutations behind aging and cancer
Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide insights into the earliest steps of cancer development and the role of mutations in healthy tissue.
October 8, 2025 — Source

Repeated sampling offers insight into glioblastoma therapy response
A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot. Their results are published in Science Translational Medicine.
October 8, 2025 — Source or Source

Scientists are collecting toenail clippings to reveal radon exposure and lung cancer risk
At 47 years of age, Emi Bossio was feeling good about where she was. She had a successful law practice, two growing children and good health. Then she developed a nagging cough. The diagnosis to come would take her breath away.
October 8, 2025 — Source

Should I worry about testicular cancer?
Testicular cancer affects about 1 in 250 men, most commonly young adults, but has a five-year survival rate over 95% if detected early. Key risk factors include family history and undescended testicles. Monthly self-exams are recommended, and any unusual changes should prompt medical evaluation. Treatment is highly effective, and most retain normal fertility and sexual function.
October 8, 2025 — Source

Smoking and biological sex shape healthy bladder tissue evolution, offering clues to cancer risk
Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor. However, the biological mechanisms behind these risk factors remain unclear. Since cancer can take decades to develop, it is important to look at healthy tissues to understand the very first steps of the disease, with the goal of improving risk prediction, prevention, and early diagnosis.
October 8, 2025 — Source

'Traffic controller' protein that protects DNA discovered, and it may help kill cancer cells
Mayo Clinic researchers discovered a protein, KCTD10, that acts as a "traffic controller" for DNA, protecting it during cell division and potentially aiding in new cancer therapies.
October 8, 2025 — Source

UCSF team uncovers breakthrough immunotherapy for colon cancer liver metastases
Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver. Despite progress in surgical therapies aimed at eradicating the cancer, many of these patients will have tumor recurrence in the liver.
October 8, 2025 — Source

Health — Cancer — October 3rd, 2025

Drop in credit score after cancer diagnosis linked to increased mortality
Patients with cancer whose credit scores decline after their diagnosis face a significantly higher risk of mortality, providing the first objective data linking financial health to physical survival.
October 3, 2025 — Source

Innovative topical cream relieves chemotherapy-induced peripheral neuropathy
Researchers at Miguel Hernández University have developed an innovative topical cream that relieves chemotherapy-induced peripheral neuropathy, improving cancer patients' quality of life.
October 3, 2025 — Source

Mastectomy linked to worsened sexual health and body image after surgery
While mastectomy is often a necessary and life-saving treatment option for many women with breast cancer, the surgery may contribute to worse sexual health, body image, and several other physical and emotional challenges after surgery, according to a new systematic review on the effects of mastectomy in women with breast cancer. Surgeons said the research underscores the importance of screening women before they undergo a mastectomy.
October 3, 2025 — Source

Newly discovered mechanism helps leukemia cells to evade the immune system
A research team at Lund University in Sweden has discovered a mechanism that helps acute myeloid leukemia cells to evade the body's immune system. By developing an antibody that blocks the mechanism, the researchers could restore the immune system's ability to kill the cancer cells in laboratory trials and in mice.
October 3, 2025 — Source

Nuclear Missile Workers Are Contracting Cancer. They Blame the Bases
Former nuclear missile operators are reporting cancer diagnoses, suspecting a link to their workplaces. The Air Force is conducting a study, expected to conclude by the end of 2025, to investigate potential health risks.
October 3, 2025 — Source

Patients value communication skills from cancer surgeons across six key areas, according to research
Patients with cancer value surgeons' communication skills in six main areas: emotional support and optimism, clear expectation setting, use of communication aids, shared decision-making tailored to patient preference, transparent discussion of prognosis, and effective team coordination. These domains contribute to patient satisfaction and treatment adherence, though more research is needed on demographic influences.
October 3, 2025 — Source

Rectal bleeding in young adults linked to 8.5 times higher risk of colorectal cancer
A recent study presented at the American College of Surgeons (ACS) Clinical Congress 2025 highlights a significant link between rectal bleeding and an increased risk of colorectal cancer in young adults. Researchers analyzed data from 443 patients under 50 who underwent colonoscopies at the University of Louisville Health System between 2021 and 2023, finding that rectal bleeding increased the odds of a colorectal cancer diagnosis by 8.5 times. Notably, 44% of these patients were diagnosed with early-onset colorectal cancer.
October 3, 2025 — Source

Scientists just cracked the mystery of why cancer immunotherapy fails
Scientists found a protein stress "Achilles' heel" in T cells that could supercharge cancer immunotherapy.
October 3, 2025 — Source

Untreated depression can make surgical outcomes worse in cancer patients
Cancer patients with untreated depression experience poorer surgical recovery, higher complication rates, and increased costs. Antidepressant treatment in depressed patients is associated with improved outcomes, including shorter hospital stays, lower readmission and mortality rates, and reduced costs compared to untreated depression, though outcomes remain best in patients without depression.
October 3, 2025 — Source

Health — Cancer — September 29th, 2025

AI tool accurately distinguishes between glioblastoma and primary central nervous system lymphoma
A Harvard Medical School AI tool, PICTURE, accurately distinguishes between glioblastoma and PCNSL, two brain cancers often misdiagnosed, aiding treatment decisions during surgery.
September 29, 2025 — Source

Cancer cell nuclear hypertrophy can suppress metastasis
In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) larger than normal. Until now, this was considered a sign that the cancer was worsening, but the exact cause and effect had not been elucidated. In this study, the KAIST research team found that cancer cell nuclear hypertrophy is not a cause of malignancy but a temporary response to replication stress, and that it can, in fact, suppress metastasis. This discovery is expected to lead to the development of new diagnostic and therapeutic strategies for cancer and metastasis inhibition.
September 29, 2025 — Source

Cancer-fighting gene plays unexpected role in pancreatic cancer tumor growth
New research from Indiana University School of Medicine scientists has revealed that a well-known cancer-fighting gene also plays an unexpected role in regulating how certain immune cells can support tumor growth. This insight into pancreatic cancer progression could lead to more effective treatments against one of the deadliest forms of cancer.
September 29, 2025 — Source

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients
A new clinical trial finds that people with a limited number of metastases from recurrent prostate cancer lived significantly longer without disease progression when they received a radiopharmaceutical drug before targeted radiation, compared with radiation alone.
September 29, 2025 — Source

Don't cut them out: Lymph nodes may be key to cancer treatment
Lymph nodes play an active role in supporting immune responses against cancer, particularly by maintaining CD8+ T cells crucial for tumor destruction. Removing lymph nodes can weaken these defenses, especially during immunotherapy, and may increase complications. Modern approaches favor targeted removal to preserve immune function, suggesting that retaining some lymph nodes benefits long-term cancer control.
September 29, 2025 — Source

Gene expression test identifies prostate cancer patients who benefit from hormone therapy
A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate cancer will benefit from adding hormone therapy to radiation after surgery - the first predictive biomarker in this setting.
September 29, 2025 — Source

Enlarged cancer cell nuclei may limit spread rather than signal severity
Enlarged nuclei in cancer cells result from DNA replication stress and actin polymerization, representing a temporary stress response rather than increased malignancy. This nuclear hypertrophy constrains metastatic potential, indicating that larger nuclei may suppress, not promote, cancer spread. These findings suggest nuclear size changes could inform new diagnostic and therapeutic approaches.
September 29, 2025 — Source

Melanoma risk calculator now factors in 16 personal traits and regional UV exposure
QIMR Berghofer has unveiled the next-generation of its world-leading melanoma risk prediction calculator to better help Australians take action against one of the country's most deadly, costly, and common cancers that claims more lives each year than the national road toll.
September 29, 2025 — Source or Watch Video

Novel immunotherapy targets common cancer mutation, offering hope for lung and prostate cancer patients
A novel immunotherapy targeting the CTNNB1_S37F mutation, common in lung and prostate cancers, has shown effective tumor elimination in preclinical models. Engineered T cells with specific T-cell receptors selectively destroyed cancer cells carrying this mutation while sparing normal cells, indicating potential for broad application in patients with solid tumors harboring shared mutations.
September 29, 2025 — Source

One-hour, low-cost HPV test could transform cervical cancer screening in Africa and beyond
A team of researchers led by Rice University, in collaboration with colleagues in Mozambique and The University of Texas MD Anderson Cancer Center, has developed a simple, affordable human papillomavirus (HPV) test that delivers results in less than an hour with no specialized laboratory required. The breakthrough could provide an option for women in low-resource settings to be screened and treated for cervical cancer in a single clinic visit, a step that global health experts say could save countless lives.
September 29, 2025 — Source

Randomized study comparing proton and photon radiation for breast cancer finds both preserve quality of life
The first randomized trial to compare photon- and proton-based radiation therapy for breast cancer finds that patients report equally strong health-related quality of life with either treatment. Patients who received proton therapy were more likely to say they would recommend or choose it again, but overall patient-reported outcomes were similar.
September 29, 2025 — Source

Shorter radiation improves patient experience but not disease control for intermediate-risk prostate cancer, trial finds
For patients with intermediate-risk, localized prostate cancer, radiation therapy delivered in five sessions reduced patient-reported side effects compared to longer courses of radiation, according to results of a large, randomized phase III trial. Patients treated with stereotactic body radiation therapy (SBRT) reported fewer declines in bowel, urinary and sexual functioning but were more likely to experience a rise in prostate-specific antigen (PSA).
September 29, 2025 — Source

Health — Cancer — September 26th, 2025

At 10 years, stereotactic body radiation therapy comparable to surgery for early-stage lung cancer
Researchers from The University of Texas MD Anderson Cancer Center will present new data at the American Society for Radiation Oncology (ASTRO) 2025 Annual Meeting demonstrating that stereotactic body radiation therapy (SBRT) and surgery achieved similar survival outcomes at 10-year follow-up for patients with early-stage non-small cell lung cancer, with radiation offering quality-of-life benefits. These findings will be presented Sept. 29 by Joe Chang, M.D., Ph.D., professor of Radiation Oncology, and Troy Kleber, M.D., resident.
September 26, 2025 — Source

How a single protein rewires leukemia cells to fuel their growth
Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead. Now, researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a single protein, IGF2BP3, that links these two processes together in leukemia cells. The protein shifts how cells break down sugar, favoring a fast but inefficient energy pathway, while also altering RNA modifications that help produce the proteins leukemia cells need to survive and multiply.
September 26, 2025 — Source

Kidney cancer cases are projected to double by 2050, says study
Global kidney cancer cases are expected to double by 2050, primarily due to modifiable risk factors such as obesity, smoking, diabetes, hypertension, and lack of exercise. Five-year survival rates range from 40% to 75% depending on region and access to care. Approximately 5--8% of cases are hereditary. Prevention through lifestyle changes can significantly reduce risk.
September 26, 2025 — Source

New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies
Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung and prostate cancer. This approach has effectively eliminated tumors in animal studies and could benefit thousands of patients with this mutation.
September 26, 2025 — Source

Tumor cells can exploit damaged tissue in the pancreas to create new environments for growth
Pancreatic cancer is an aggressive disease, and unlike many other cancers, survival rates have barely improved. Researchers at Karolinska Institutet, in collaboration with the Department of Pathology at Karolinska University Hospital, have now shown that pancreatic tumor cells not only spread in the connective tissue--rich environment that is a well-known characteristic of pancreatic cancer but also grow into damaged parts of normal pancreatic tissue. There, the cancer can create its own environment.
September 26, 2025 — Source or Source

Health — Cancer — September 25th, 2025

App may improve palliative care for adults with incurable cancer
Ying Yu, Ph.D., from Fudan University in Shanghai, and colleagues explored whether adding a palliative care educational app to clinical palliative care could enhance HRQoL in homebound patients with incurable cancer. The analysis included 147 adults (Karnofsky Performance Status ≤70) receiving palliative care who had consistent family caregivers.
September 25, 2025 — Source

Bacteria coated liquid metal nanoparticles wipe out tumors in mice
New nanoparticles made from bacteria and liquid metal locate tumors, trigger immune attacks, and destroy cancer in mice under near infrared light with no major side effects.
September 25, 2025 — Source

Diet and medication combo interrupts growth of aggressive childhood neuroblastoma tumors, study finds
Researchers at Children's Hospital of Philadelphia (CHOP) found that combining a specialized diet with an approved medication interrupts the growth of high-risk neuroblastoma, a deadly pediatric cancer, by reprogramming tumor behavior.
September 25, 2025 — Source

Sniffing out cancer: Volatile organic compounds show promise for early multi-cancer detectio
A research team led by Prof. Chu Yannan at the Hefei Institutes of Physical Science, Chinese Academy of Sciences, has uncovered a new way to detect cancer early—by analyzing the invisible chemical "scents" that the body gives off.
September 25, 2025 — Source

UPR modulators show promise in treating cancer-related bone disease
Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation. Much of this processing occurs in the endoplasmic reticulum (ER) of every cell. However, any disruptions in protein homeostasis can be very stressful to the ER, and when the ER gets overwhelmed, a safety system called the Unfolded Protein Response (UPR) engages to slow down protein synthesis and allow the ER to catch up.
September 25, 2025 — Source

Health — Cancer — September 22nd, 2025

A hormone that silences the immune system may unlock new cancer treatments
Study uncovers hormone's role in weakening body's defenses against cancer.
September 22, 2025 — Source

Boosting drug delivery with spiky nanorobots
Researchers engineered magnetic nanorobots that carry anticancer drugs and penetrate tumor cell membranes, improving chemotherapy effectiveness.
September 22, 2025 — Source

Engineered gut bacteria improve survival outcomes in colorectal cancer tumors
In a new study that combines synthetic biology with cancer immunotherapy, researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and Central South University in China have developed an engineered strain of gut-homing bacteria that stimulates potent antitumor immune responses against colorectal cancer (CRC).
September 22, 2025 — Source

Metabolic markers may predict breast cancer in high-risk women
Breast cancer remains the most common cancer and the leading cause of cancer-related death among women worldwide, with incidence rates continuing to rise. However, known risk factors, including genetics and lifestyle, do not fully explain the upward trend. Researchers are increasingly turning to metabolomics—the large-scale study of small molecules in biological systems—as a promising avenue for identifying new risk factors and improving prediction methods for breast cancer.
September 22, 2025 — Source

Study reports on recent trends in opioid prescribing for patients with cancer
A recent analysis reveals a modest decline from 2016 to 2020 in new and additional opioid prescriptions for patients with cancer. Among those patients with metastatic cancer, prescribing remained stable for those reporting any pain and declined steeply for those reporting no pain.
September 22, 2025 — Source

When cancer cells feel squeezed, they become more dangerous
New research shows that cancer cells don't just grow; they adapt when stressed. When squeezed inside tissues, they transform into more invasive, drug-resistant versions of themselves. A protein called HMGB2 helps flip this dangerous switch, giving the cells new powers to escape. The findings reveal how the tumor's environment itself can drive cancer's deadly flexibility.
September 22, 2025 — Source

Health — Cancer — September 19th, 2025

Gut bacterial adhesion mechanism revealed as target for novel colorectal cancer therapies
Fusobacterium nucleatum (F. nucleatum) is an anaerobic bacterium notably enriched in the gut microbiota of colorectal cancer (CRC) patients and may play a role in CRC both by colonizing tumor cells and suppressing immune mechanisms. Understanding how this bacterium adheres to cancer cells could provide key targets for developing novel antitumor therapies.
September 19, 2025 — Source

Health researchers discuss Medicaid cancer screening trends, best practices
New Jersey has the 10th-highest rate of cancer incidence in the United States. It is the second leading cause of death in New Jersey, and thousands of residents die from preventable cancers each year.
September 19, 2025 — Source

Scientists Find a Tattoo--Cancer Link—But It's Not What You'd Expect
New research finds a surprising link between a person's risk of melanoma and the amount of tattoos they sport.
September 19, 2025 — Source

Self-collection for HPV testing can improve cervical cancer screening rates among Asian American women
Asian American women given the option to collect their own sample for human papillomavirus (HPV) testing after an educational workshop completed cervical cancer screening at much higher rates compared with workshop attendees who were referred to clinics, according to results presented at the 18th AACR Conference on the Science of Cancer Health Disparities, held September 18--21, 2025.
September 19, 2025 — Source

Sugary drinks may increase risk of metastasis in advanced colorectal cancer
A new study from researchers at The University of Texas MD Anderson Cancer Center shows that the glucose-fructose mix found in sugary drinks directly fuels metastasis in preclinical models of advanced colorectal cancer.
September 19, 2025 — Source

Young adult cancer survivors may face elevated social risks
"There are now more than 18 million cancer survivors in the United States, many living a decade or more after diagnosis. While survivorship is a success story, a cancer diagnosis can heighten vulnerability to social risks such as food, housing, and transportation insecurity," said study presenter Ami E. Sedani, PhD, MPH, assistant professor of epidemiology at UTHealth Houston School of Public Health in Dallas.
September 19, 2025 — Source

Health — Cancer — September 16th, 2025

Biomarkers linked to side effects from cancer immunotherapy
A team led by UT Southwestern Medical Center scientists has identified early signals from the immune system that could help predict which cancer patients are most likely to develop harmful side effects from immunotherapy. The findings, published in the Journal for ImmunoTherapy of Cancer, offer a path toward tests to help doctors tailor care for at-risk patients.
September 16, 2025 — Source

Both weights and high intensity interval training offer health benefits for cancer survivors
Research from Edith Cowan University (ECU) has revealed that both resistance training and high intensity interval training (HIIT) produced sufficient levels of myokines to help in the fight against cancer.
September 16, 2025 — Source

Deep learning tool improves accuracy of lung nodule malignancy detection
An artificial intelligence (AI) deep learning tool that estimates the malignancy risk of lung nodules achieved high cancer detection rates while significantly reducing false-positive results. Results of the study, which used data from large, multi-site lung cancer screening trials, were published today in Radiology, a journal of the Radiological Society of North America (RSNA).
September 16, 2025 — Source or Source

Novel biotechnical vector integrates viral and synthetic features for targeted cancer therapy
Gene therapy offers the possibility of addressing cancer at its molecular roots by targeting disease-causing genes rather than relying solely on surgery, chemotherapy, or radiotherapy. Among RNA-based strategies, microRNA (miRNA) sponges and short-hairpin RNAs (shRNAs) have emerged as promising tools to silence oncogenes and restore tumor-suppressor pathways. However, clinical application remains constrained by delivery inefficiency, instability, and off-target toxicity. Viral and non-viral vectors each present strengths and limitations: while viral vectors provide high transfection efficiency, they often cause immune responses and mutagenesis risks; non-viral carriers are safer but lack sufficient delivery efficiency.
September 16, 2025 — Source

Scientists find a smarter way to activate the immune system against cancer
Scientists have developed a smarter way to activate the immune system against cancer, potentially making treatments safer and more precise.
September 16, 2025 — Source

Too soon to tell if 'liquid biopsies' help more than harm in cancer screening
"Liquid biopsy" tests using blood samples to screen for multiple types of cancer are attracting much attention, for their potential to catch unseen tumors.
September 16, 2025 — Source

Triple negative breast cancer exploits lymph node niches to block immune defense
In almost all solid tumors - i.e. cancers with a solid tissue structure - the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease. Lymph node involvement has a significant influence on the choice of treatment and the chances of survival for patients. In particular, solid tumors in the breast, on the skin or in the gastrointestinal tract use the lymphatic system as the main route for distant metastasis, for example to the lungs, liver and bones.
September 16, 2025 — Source

Two-part prodrug system activates immune attack only in tumor's unique environment
Scientists have developed a smarter way to activate the immune system against cancer, potentially making treatments safer and more precise.
September 16, 2025 — Source

Health — Cancer — September 9th, 2025

Algorithm uses fluid flow to predict where deadly brain cancer may spread next
Glioblastoma is a devastatingly effective brain cancer. Doctors can cut it out or blast it with radiation, but that only buys time. The cancer has an insidious ability to hide enough tumor cells in tissue around the tumor to allow it to return as deadly as ever.
September 9, 2025 — Source

'Bottlebrush' particles deliver big chemotherapy payloads directly to cancer cells
Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells.
September 9, 2025 — Source

Circulating tumor DNA may guide immunotherapy use in limited-stage SCLC, new study shows
The research, led by scientists at the National Cancer Center of China, assessed ctDNA in 177 patients with LS-SCLC treated with chemoradiotherapy (CCRT), 77 of whom received consolidation immune checkpoint inhibitors (ICIs). Circulating tumor DNA was measured at multiple time points to evaluate its ability to predict survival outcomes and immunotherapy benefits.
September 9, 2025 — Source

City of Hope launches innovative national clinical trials model to expand access to cancer treatments
City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., launched an innovative national clinical trials model to expand access to emerging life-saving cancer treatments to more patients across the country. This model simplifies the opening of new trial locations and streamlines patient enrollment with the goal of accelerating the development of new cancer treatments and improving clinical care.
September 9, 2025 — Source

FANSS study demonstrates feasibility of U.S.-based lung cancer screening in Asian female nonsmokers
Results from the Female Asian Nonsmoker Screening Study (FANSS) highlight the potential value of low-dose CT (LDCT) screening for lung cancer among a growing but underserved population: Asian women with no history of smoking.
September 9, 2025 — Source

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer
New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.
September 9, 2025 — Source or Source

LuCE study identifies key communication barriers between lung cancer patients and caregivers
A large-scale survey conducted by Lung Cancer Europe (LuCE) has identified critical communication barriers that affect information access, understanding, and shared decision-making among lung cancer patients and caregivers across Europe.
September 9, 2025 — Source

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC
A new study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC) demonstrates that monitoring circulating tumor DNA (ctDNA) can refine and personalize the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).
September 9, 2025 — Source

New tool can predict where deadly brain cancer might reappear
Glioblastoma is a devastatingly effective brain cancer. Doctors can cut it out or blast it with radiation, but that only buys time. The cancer has an insidious ability to hide enough tumor cells in tissue around the tumor to allow it to return as deadly as ever.
September 9, 2025 — Source

Novel immunotherapy strategy shows promising long-term survival in certain advanced NSCLC patients
A new study presented reports encouraging long-term survival outcomes from an experimental viral immunotherapy, CAN-2409, in patients with advanced non-small cell lung cancer (NSCLC) who previously failed to respond adequately to immune checkpoint inhibitors (ICI).
September 9, 2025 — Source

Radioactive iodine therapy used for canine cancer treatment
Radioactive iodine therapy used for canine cancer treatment
September 9, 2025 — Source

Real-time measurement of boron in individual cancer cells could enhance understanding of tumor-killing drugs
A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumors in some cancers.
September 9, 2025 — Source

Smoking status should influence lung cancer staging, new study shows
The University of Kentucky Markey Cancer Center's Graham Warren, M.D., Ph.D., and international collaborators have led a groundbreaking study that could change the way lung cancer is diagnosed and treated.
September 9, 2025 — Source

Sponge-like gold nanoparticles could upgrade ovarian cancer diagnostics
A project led by University of Queensland Ph.D. student Javeria Bashir has produced specially crafted gold nanoparticles that can highlight cancer markers in samples like urine, saliva, or blood. Bashir said she hoped to use her gold nanoparticles to help improve survival rates for a cancer that is considered particularly deadly.
September 9, 2025 — Source

Study highlights communication gaps and need for shared decision-making in lung cancer diagnosis
A large-scale survey conducted by Lung Cancer Europe (LuCE) has identified critical communication barriers that affect information access, understanding, and shared decision-making among lung cancer patients and caregivers across Europe.
September 9, 2025 — Source

Study highlights potential value of low-dose CT screening for lung cancer among Asian women
Results from the Female Asian Nonsmoker Screening Study (FANSS) highlight the potential value of low-dose CT (LDCT) screening for lung cancer among a growing but underserved population: Asian women with no history of smoking.
September 9, 2025 — Source

Subcutaneous amivantamab every 4 weeks plus lazertinib shows high response rate in EGFR-mutated NSCLC
A new analysis from the PALOMA-2 study shows that subcutaneous administration of amivantamab every four weeks (Q4W), in combination with daily oral lazertinib, yields a high objective response rate in patients with previously untreated EGFR-mutated advanced non-small cell lung cancer (NSCLC).
September 9, 2025 — Source

Surgery after EGFR TKI shows promise in prolonging progression-free survival in metastatic NSCLC
A randomized Phase II trial from National Taiwan University Hospital reports early evidence that resecting the primary thoracic tumor following EGFR tyrosine kinase inhibitor (TKI) therapy may prolong disease control in patients with metastatic EGFR-mutated non-small cell lung cancer (NSCLC).
September 9, 2025 — Source

Health — Cancer — September 5th, 2025

Discovery of a new biomarker for early detection of bladder cancer in both dogs and humans
Bladder cancer is a painful and often recurring disease, not just for humans, but for our canine companions as well. Urothelial carcinoma, the most common type of bladder cancer, affects both species in remarkably similar ways—from the genetics to the clinical progression. This shared burden also means a shared challenge: how to detect and treat the aggressive form of the disease that's responsible for most relapses.
September 5, 2025 — Source

Cancer study identifies why patients do not respond to personalized immune therapy, sparking new vaccine
Immune-checkpoint therapy (ICT), which attempts to harness a patient's own immune system to fight cancer, has revolutionized cancer care over the past two decades. However, many patients do not respond to this therapy, and drug resistance due to immune-evasive (or "cold") tumors remains poorly understood.
September 5, 2025 — Source

New radiotheranostic targets identified for diagnosis and treatment of endometrial cancer
Two molecular targets—human epidermal growth factor 2 (HER2) and cluster of differentiation 24 (CD24)—are highly promising candidates for new nuclear diagnostics and therapeutics for endometrial cancer, according to new research published in The Journal of Nuclear Medicine.
September 5, 2025 — Source

Why discussing sex is important for patients after treatment for gynecological cancer
Anita Paulsen is a nurse and sexologist. She recently defended her doctoral thesis on sexual health communication after gynecological cancer. Through her work and research, she has met many cancer survivors who miss the intimacy in their lives.
September 5, 2025 — Source

Health — Cancer — September 4th, 2025

Dietary changes could provide a therapeutic avenue for brain cancer
Glioblastomas are the deadliest form of malignant brain tumor, and most patients diagnosed with the disease live only one or two years. In these tumors, normal cells in the brain become aggressive, growing rapidly and invading the surrounding tissue. The resulting cancer cells are metabolically different from their neighboring healthy cells.
September 4, 2025 — Source or Watch Video

DNA analysis shows colorectal cancer has unique microbial fingerprint
Colorectal cancer is unique in having its own microbial "fingerprint," according to new research from the University of East Anglia.
September 4, 2025 — Source

Novel embolization-on-a-chip model allows testing various embolic agent classes to treat liver cancer
Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents. This novel platform reflects the microenvironment of liver tumors, particularly a functional and perfusable microvasculature that can be embolized. This in vitro tool aligns with the National Institutes of Health (NIH) efforts to reduce animal testing and promote alternative methods, including microfluidic devices that mimic human organs.
September 4, 2025 — Source

Prolonged use of injectable contraceptive tied to brain tumor diagnoses
From Case Western Reserve University School of Medicine and Cleveland Clinic, investigators report that depot medroxyprogesterone acetate use was associated with a higher relative risk of meningioma brain tumor diagnosis in US women, with risk concentrated after more than four years of exposure or initiation at older than 31 years.
September 4, 2025 — Source

Squeezing through tiny blood vessels may trigger melanoma cells to spread
Nine of the 10 most common cancer deaths in Australia are caused by solid tumors, but in most cases it's the cancer's spread to other parts of the body—known as metastasis—that proves fatal.
September 4, 2025 — Source

Startup spun out of Nobel Laureate's lab teams with Eli Lilly to fight cancer with AI
Lila Biologics, a startup that spun out of Nobel Laureate David Baker's lab at the University of Washington, announced a collaboration with pharmaceutical giant Eli Lilly to develop therapies for treating solid tumors.
September 4, 2025 — Source

Study shows how smoking drives pancreatic cancer
A new study explains why smokers have a higher chance of developing pancreatic cancer and why they tend to have worse outcomes than nonsmokers.
September 4, 2025 — Source

Sugar-Coated Nanoparticles Boost Cancer Drug Efficacy
Over a tenth of breast cancer diagnoses are for triple-negative breast cancer. Triple-negative breast cancer (TNBC) gets its name because it lacks three common targets: estrogen, progesterone, and HER2. It disproportionately affects young women, especially African American women, making it an urgent priority for new treatment strategies.
September 4, 2025 — Source

Survival in people with myeloma nearly doubled since 2005
People diagnosed with multiple myeloma—one of the most common forms of blood cancer—are now living nearly twice as long on average as they were in 2005, according to a new study.
September 4, 2025 — Source

Health — Cancer — September 1st, 2025

How B-cell receptor types shape lymphoma cell survival and growth
A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the most common and aggressive forms of non-Hodgkin lymphoma, according to findings published in Science Advances.
September 1, 2025 — Source

How pediatric brain tumors grow: Blocking a chemical messenger could offer new route to treatment
The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors. Although this type of tumor is usually not life-threatening, the unchecked growth of tumor cells can disrupt normal brain development and function.
September 1, 2025 — Source

Urine test can assess risk of kidney cancer recurrence
A simple urine test that can assess the risk of kidney cancer recurrence at an early stage could spare patients from frequent X-ray examinations and thus reduce the associated radiation, anxiety and costs.
September 1, 2025 — Source

Health — Cancer — August 29th, 2025

AI models can help predict in-hospital mortality in ICU patients with lymphoma
Ling Xu, from the Guangzhou University of Traditional Chinese Medicine in Dongguan, China, and colleagues developed and validated ML models to predict in-hospital mortality in adult ICU patients with lymphoma in a retrospective cohort study using data from the Medical Information Mart for Intensive Care IV database. Fifteen machine learning models were developed and compared using receiver operating characteristic curves and an area under the curve (AUC) analysis.
August 29, 2025 — Source

Cancer can smuggle mitochondria in neighboring cells and put them to work
Cancer cells provide healthy neighboring cells with additional mitochondria to put them to work. This has been demonstrated by researchers at ETH Zurich in a new study. In this way, cancer is exploiting a mechanism that frequently serves to repair damaged cells.
August 29, 2025 — Source

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease
Clonal hematopoiesis (CH) is an acquired mutation in blood stem cells that is linked to risk of developing leukemia and other blood cancers. It is also associated with a more than 1.5-fold increased risk of cardiovascular disease, including coronary heart disease, heart failure and arrhythmias. The most common driver genes that can lead to CH are DNMT3A, TET2 and ASXL1, which represent about 80% of CH cases. Research has shown that over 10% of people 70 years old and older carry one or more of these mutations and the risk increases with age.
August 29, 2025 — Source

Data analysis reveals 1 in 12 patients with multiple cancers carries inherited genetic risk
A new study reveals that about one in 12 patients who are diagnosed with two or more different types of cancer were born with a mutation in a known cancer risk gene. This discovery could reshape how genetic testing is offered to cancer patients.
August 29, 2025 — Source

Leukemia stem cell-based method aids relapse prediction in acute myeloid leukemia
Si-Qi Li, from the Peking University People's Hospital in Beijing, and colleagues assessed the ability of the LSC-based method and the traditional multiparameter flow cytometry (MFC) assay to predict leukemia relapse after long-term follow-up. The analysis included 360 patients with AML who received allografts between July 2018 and November 2019.
August 29, 2025 — Source

New off-the-shelf immunotherapy for metastatic kidney cancer could help improve outcomes
UCLA researchers have developed a new kind of immunotherapy that uses specially engineered immune cells equipped with built-in weapons to attack kidney cancer tumors and reprogram their protective environment - all without the need to customize treatment for each individual patient.
August 29, 2025 — Source

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma
Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics. Despite its clinical significance, large-scale proteomic studies on GSRCC remain scarce, limiting our molecular understanding of the disease. Advanced mass spectrometry (MS)-based proteomics is crucial for identifying key biomarkers and drug targets, thereby enabling more effective therapeutic strategies.
August 29, 2025 — Source

Scientists develop off-the-shelf immunotherapy for metastatic kidney cancer
UCLA researchers have developed a new kind of immunotherapy that uses specially engineered immune cells equipped with built-in weapons to attack kidney cancer tumors and reprogram their protective environment—all without the need to customize treatment for each individual patient.
August 29, 2025 — Source

Unlocking the immune system: Cellular 'toolkit' could reprogram cells for cancer therapy
An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells. The discovery, published in Immunity, could pave the way for more precise and personalized cancer immunotherapies.
August 29, 2025 — Source

Health — Cancer — August 22nd, 2025

AI detects early prostate cancer in more than 80% of samples missed by pathologists
Men assessed as healthy after a pathologist analyzes their tissue sample may still have an early form of prostate cancer. Using AI, researchers at Uppsala University have been able to find subtle tissue changes that allow the cancer to be detected long before it becomes visible to the human eye.
August 22, 2025 — Source or Source

Apple Watch Warnings Reveal Woman's Hidden Brain Tumor
The woman said the Apple Watch was vital in pushing her toward medical care earlier than she might have otherwise sought it out.
August 22, 2025 — Source

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation
Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality. Antioxidant-1 (ATOX1) has been implicated in oncogenic processes across various cancer types; however, its specific role in HCC remains unclear. This study aimed to investigate the function of ATOX1 and its underlying molecular mechanisms in HCC.
August 22, 2025 — Source

Breast cancer drug side effects: Study reveals how tamoxifen raises risk of secondary tumors in uterus
An international research team has identified a previously unknown mechanism by which the breast cancer drug tamoxifen can increase the risk of secondary tumors in the uterus.
August 22, 2025 — Source

Encounters matter in cancer care: Health care professionals can play a key role in restoring patients' sense of control
A cancer diagnosis often comes as a shock, leaving people feeling as though they have lost control over their lives. Conducted at the University of Eastern Finland, a recent collaborative autoethnographic study explored how communication and encounters with health care professionals influenced one patient's sense of control during her treatment journey.
August 22, 2025 — Source

Insights into the clinical presentation and management of sellar chondrosarcomas
Chondrosarcomas are a malignant form of bone cancer that is composed of cartilage-forming tumor cells. Sellar chondrosarcomas, which occur in the sellar region at the base of the skull, are a very rare manifestation of chondrosarcoma, making up only around 0.2% of all tumors found in the skull. Historically, transcranial (or through the skull) surgery is the main treatment option for these tumors - however, with the advancement of surgery techniques, more non-invasive options have become popular for treatment.
August 22, 2025 — Source

Lymphoma itself, not just treatment, can trigger rapid immune system and tissue aging
A new study led by a team of researchers at Moffitt Cancer Center reveals that lymphoma can accelerate the biological aging of the immune system and other tissues, providing new insight into how cancer reshapes the body beyond tumor growth.
August 22, 2025 — Source

Nanopore technique tracks DNA damage to aid cancer therapy and radiation response
Scientists developed a fast DNA damage test for radiation that could guide cancer care and help responders deliver personalized treatment during radiological emergencies.
August 22, 2025 — Source

Health — Cancer — August 21st, 2025

Apple Watch helps user discover life-changing brain tumor
The Apple Watch's health features have once again played a part in flagging a potential health problem. A 57-year-old woman from Brighton, East Sussex says her Apple Watch alerted her to an issue that ultimately led doctors to uncover a brain tumor.
August 21, 2025 — Source

Australian researchers identify GATOR1 complex as key to preventing lymphoma
Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.
August 21, 2025 — Source

Broccoli can have a protective effect against colon cancer, study reveals
The broccoli and Brussels sprouts that often get pushed to the edge of the plate might aid in reducing the risk of colon cancer.
August 21, 2025 — Source

Can the way we talk about cancer change how we interact with the disease?
In modern medicine, few diseases are as steeped in emotive and metaphorical language as cancer. It's often spoken about as a battle pitched against a cunning enemy. A foe to be beaten. These phrases are so common that we don't think twice about them, but they deeply affect how we understand cancer, how people experience it and how we care for the people who live with it.
August 21, 2025 — Source

CRISPR screening identifies key targets to strengthen CAR NK cell therapies
The study, published in Cancer Cell, opens new avenues for discovering approaches to enhance the antitumor activity of chimeric antigen receptor (CAR) NK cell therapies against multiple cancer types via PreCiSE, a comprehensive CRISPR discovery platform optimized for primary human NK cells.
August 21, 2025 — Source

Dual-mode tracer could enable surgeons to see and 'hear' prostate cancer
A preclinical evaluation of a new "dual-mode" tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.
August 21, 2025 — Source

Genetic study suggests ways to catch blood cancer earlier
As we age, our cells replicate, and the DNA in these cells can acquire mistakes—or mutations—every time the sequence is copied. Most newly acquired mutations are harmless, but some can tip the balance toward cancer development later in life.
August 21, 2025 — Source

Key genes that act as a brake on blood cancer growth reveal potential treatment targets
Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.
August 21, 2025 — Source

New 'dual-mode' tracer agent enhances precision in prostate cancer procedures
A preclinical evaluation of a new 'dual-mode' tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.
August 21, 2025 — Source

New formulation of chemotherapy drug opens doors to advanced cancer treatment options
University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.
August 21, 2025 — Source

New study uncovers a surprising mechanism of resistance to immunotherapy
A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of resistance to immunotherapy: cancer's ability to injure nearby nerves.
August 21, 2025 — Source

Novel topical fluorescent imaging technique rapidly and safely detects basal cell carcinoma
Basal cell carcinoma is the most common skin cancer, and early treatment typically leads to excellent outcomes. Definitive diagnosis, however, depends on biopsy, an invasive procedure that can be painful and leave scars. In addition, biopsies can delay diagnosis weeks to months and require patients to return for treatment after histopathologic confirmation.
August 21, 2025 — Source

Repackaged cancer drug boosts delivery to tumors, improves combination therapies
University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.
August 21, 2025 — Source

Scientists solve 30-year mystery of a hidden nutrient that shields the brain and fights cancer
Scientists have finally uncovered the missing link in how our bodies absorb queuosine, a rare micronutrient crucial for brain health, memory, stress response, and cancer defense. For decades, researchers suspected a transporter had to exist, but it remained elusive—until now.
August 21, 2025 — Source

Weight loss trial reports success for breast cancer patients at one year mark
Breast cancer patients who participated in a remote weight loss intervention program lost an average of 4.7% of their baseline body weight after one year, while those in the education only control group gained an average 1% of their baseline weight, according to a new report from Dana-Farber Cancer Institute investigators.
August 21, 2025 — Source

Health — Cancer — August 19th, 2025

AI hybrid strategy improves mammogram interpretation
A hybrid reading strategy for screening mammography, developed by Dutch researchers and deployed retrospectively to more than 40,000 exams, reduced radiologist workload by 38% without changing recall or cancer detection rates.
August 19, 2025 — Source

How HPV reprograms immune cells to help cancer grow
The most common cancer-causing strain of human papillomavirus (HPV), HPV16, undermines the body's defenses by reprogramming immune cells surrounding the tumor, according to new research from the Keck School of Medicine of USC.
August 19, 2025 — Source

HPV16 reprograms immune cells to weaken cancer defenses
The most common cancer-causing strain of human papillomavirus (HPV), HPV16, undermines the body's defenses by reprogramming immune cells surrounding the tumor, according to new research from the Keck School of Medicine of USC. In mice, blocking this process boosted the ability of experimental treatments for HPV to eliminate cancer cells.
August 19, 2025 — Source

Hybrid reading strategy for screening mammography reduces radiologist workload
A hybrid reading strategy for screening mammography, developed by Dutch researchers and deployed retrospectively to more than 40,000 exams, reduced radiologist workload by 38% without changing recall or cancer detection rates. The study, which emphasizes AI confidence, was published today in Radiology, a journal of the Radiological Society of North America (RSNA).
August 19, 2025 — Source

Metabolic pathway presents promising new target for treating rare, aggressive childhood cancer
A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to improve treatments for patients.
August 19, 2025 — Source

New options are advancing rare brain cancer treatment
Art Sullivan, a 38-year-old Ironman athlete, and Josh Lehman, 48, who works at the University of Rochester, are connected by an unlikely foe: a type of brain tumor called an astrocytoma that tends to afflict younger adults. They are also benefiting from the first new treatment for this cancer in decades—and it's changing their lives.
August 19, 2025 — Source

Radioactive ion beams successfully treat animal tumors in study
The study marks a decisive step toward the further development of particle therapy and is based on intensive collaboration between different GSI departments and FAIR pillars and with the Ludwig-Maximilians-Universität in Munich (LMU), Department of Medical Physics, who contributes to the BARB (Biomedical Applications of Radioactive Ion Beams) project as Associated Partner with a team led by Professor Katia Parodi.
August 19, 2025 — Source

Study finds link between epigenetic aging and colorectal cancer risk in postmenopausal women
In this study led by Su Yon Jung from the University of California, Los Angeles, researchers found a strong association between accelerated epigenetic aging and an increased risk of colorectal cancer in postmenopausal women. The study also indicated that lifestyle factors influence this risk.
August 19, 2025 — Source

Synthesis of a molecule found in guava plants offers hope in fighting liver-related cancers
You may not be aware that most of the medicines that have been approved for treatment are rooted in nature. For example, the bark of willow trees has been called nature's aspirin because it contains a chemical called salicin. The human body converts salicin into salicylic acid, which relieves pain and fights fevers.
August 19, 2025 — Source

The First At-Home Cervical Cancer Screening Wand: Cost, Insurance Coverage and How It Works
The Teal Wand allows you to screen yourself for cervical cancer from the comfort of your home. This is everything you need to know.
August 19, 2025 — Source

Using bacteria to sneak viruses into tumors
Researchers engineered bacteria to deliver hidden viruses into tumors, bypassing the immune system and unleashing a new strategy for targeted cancer treatment.
August 19, 2025 — Source

Health — Cancer — August 16th, 2025

Do hot drinks really give you cancer? A gut expert explains
When you order a coffee, do you ask for it to be "extra hot?"
August 16, 2025 — Source

Study reveals genetic switch that helps leukemia cells evade chemotherapy
One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy—and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this. Now, new research from The Jackson Laboratory (JAX) points to a previously unknown molecular mechanism behind that chemoresistance, and a way to potentially disarm it.
August 16, 2025 — Source

Health — Cancer — August 11th, 2025

Boehringer wins US approval for cancer drug
Boehringer Ingelheim GmbH won approval in the U.S. for its drug to treat a challenging form of lung cancer, offering a growth avenue for the privately-held German pharmaceuticals company.
August 11, 2025 — Source

Diabetes risk in childhood cancer survivors targeted through digital health monitoring
A researcher at The University of Texas at Arlington is helping a leading national cancer center explore how wearable devices could help childhood cancer survivors avoid long-term health complications such as diabetes and heart disease.
August 11, 2025 — Source

New imaging technique reveals how antibodies reshape cancer cell receptors
A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.
August 11, 2025 — Source

New tool aims to improve lung cancer prevention, screening, and treatment
Although lung cancer is the leading cause of cancer and cancer deaths worldwide, screening rates have remained low, leading to delayed diagnoses and care and ultimately resulting in high mortality rates.
August 11, 2025 — Source

Novel cancer drug may boost chemotherapy effectiveness—even in resistant tumors
A cancer drug could enhance how patients respond to chemotherapy even in treatment-resistant tumors. The drug works by disarming a key defense mechanism that tumors use to protect themselves from treatment. In preclinical models, it has already shown promise in making chemotherapy-resistant cancers more responsive to therapy.
August 11, 2025 — Source

RSPO2 gene identified as key driver in metastatic prostate cancer
A new research paper was published in Volume 16 of Oncotarget on July 25, 2025, titled "Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer."
August 11, 2025 — Source

Scientists uncover new way in which cells tolerate anticancer drugs
Researchers from Tokyo Metropolitan University have discovered a new pathway by which cells counteract the action of alovudine, an important antiviral and anticancer drug.
August 11, 2025 — Source

Study reveals targeted therapy for aggressive liver cancer
Among the many forms of liver cancer, hepatocellular carcinoma (HCC) is the most common and one of the leading causes of cancer-related deaths worldwide. It is a complex disease with multiple aggressive subtypes that are difficult to treat.
August 11, 2025 — Source

Health — Cancer — August 8th, 2025

Blood test for multiple myeloma offers alternative to bone marrow biopsies
Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions. The new method, known as SWIFT-seq, utilizes single-cell sequencing to profile circulating tumor cells (CTCs) in the blood, offering a non-invasive alternative to traditional bone marrow biopsies.
August 8, 2025 — Source

Genomics-guided tool helps guide immunotherapy choices for advanced kidney cancers
A study led by Roswell Park Comprehensive Cancer Center helps explain why a rare and hyper-aggressive subtype of kidney cancer is susceptible to immunotherapy—information that helped researchers create a first-of-its-kind tool to guide treatment decisions for advanced kidney cancers.
August 8, 2025 — Source

International commission calls for action against hepatocellular carcinoma
Liver cancer is the sixth most common cancer as well as the third highest cause of cancer-related mortality worldwide. In particular, a subtype of liver cancer known as hepatocellular carcinoma accounts for around 80% of all liver cancer cases. Given the increasing disease burden of hepatocellular carcinoma globally, a Commission consisting of experts in a wide range of fields -- from clinical medicine to public health -- has now been established to tackle this issue.
August 8, 2025 — Source

Mouse study reveals gut microbe balance may be key factor in early-onset colorectal cancer
With colorectal cancer on the rise in people under 50, researchers at the University of Illinois Urbana-Champaign are looking at the colon's tiniest inhabitants to reveal causes and potential treatments.
August 8, 2025 — Source

New blood test offers breakthrough in myeloma diagnosis and monitoring
Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions. The new method, known as SWIFT-seq, utilizes single-cell sequencing to profile circulating tumor cells (CTCs) in the blood, offering a non-invasive alternative to traditional bone marrow biopsies.
August 8, 2025 — Source

Targeting sleeping tumor cells: Oncogene location may determine neuroblastoma's resistance to cancer therapy
Neuroblastoma can be a particularly insidious cancer. In about half of all cases, tumors regress, even without therapy. In the other half, tumors grow very quickly. These tumors often respond well to chemotherapy at first, but usually return after one to two years. A characteristic feature of such aggressive neuroblastoma cells is an abnormally high number of copies of the oncogene MYCN.
August 8, 2025 — Source

Health — Cancer — August 4th, 2025

A saliva-based test for breast cancer might be near
In a small new study, a handheld saliva-sampling device successfully detected breast cancer 100% of the time, researchers said.
August 4, 2025 — Source

Gap in oncology training leaves doctors unprepared for cannabis questions
Evidence suggests as many as 40% of adults with cancer turn to marijuana—more properly known as cannabis—to manage symptoms like pain, nausea and anxiety, and many want guidance from their physicians. Yet a new national study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) finds that most oncologists-in-training, or fellows, feel underprepared to unprepared to manage this increasingly common aspect of their patients' care.
August 4, 2025 — Source

Newly found mechanism can supercharge the immune system against cancers
New research has uncovered a novel mechanism that may help explain why some people with cancer respond remarkably well to immunotherapy while others don't.
August 4, 2025 — Source

Health — Cancer — August 3rd, 2025

How leukemia virus stays hidden in the body—and a key to future treatments
A research team from Kumamoto University has made a new discovery that reveals how the human T-cell leukemia virus type 1 (HTLV-1) silently persists in the body. Their finding potentially lays the foundation for new therapeutic approaches.
August 3, 2025 — Source

Health — Cancer — August 2nd, 2025

Smart RNA nanodevices reprogram themselves to silence genes in cancer cells
Reprogrammable RNA nanoparticles activate only in cancer cells to deliver targeted gene-silencing therapy while avoiding off-target effects, immune activation, and unnecessary drug exposure.
August 2, 2025 — Source

Health — Cancer — August 1st, 2025

Changes in Missouri law linked to increased breast cancer screening rates
Amy K. Patel, M.D., from The Breast Care Center at Liberty Hospital in Missouri, and colleagues examined the effect of Missouri law changes (i.e., expanding mammography coverage to include annual screening from age 40) on overall screening rates and use of DBT in a retrospective study using a national claims database for 2015 to 2022.
August 1, 2025 — Source

Final clinical trial data for advanced kidney cancer treatment shows efficacy of two-drug combination
The study reports final clinical data and biomarker analyses from the Phase 3 KEYNOTE-426 trial, which compared the drug combination pembrolizumab plus axitinib versus the single drug sunitinib for patients with previously untreated advanced clear cell renal cell carcinoma, the most common type of kidney cancer.
August 1, 2025 — Source

First person in US treated with novel radiopharmaceutical therapy for breast cancer
The medicine used in this clinical trial contains actinium-225, a highly potent alpha-emitting radiopharmaceutical therapy that was first developed for a subtype of gastroenteropancreatic neuroendocrine tumors, which are rare and can form in the pancreas and the gastrointestinal tract. The alpha-emitting radiopharmaceutical therapy is intended to work by passing through the blood to stick to cancer cells, delivering powerful and precise radiation without harming healthy cells.
August 1, 2025 — Source

Melanoma 'cellular compass' discovery could help curb metastasis
Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body. The malignant cells become dependent on this protein to migrate, pointing to new strategies for impeding metastasis.
August 1, 2025 — Source

New radioimmunotherapy approach eliminates cancer stem cells in preclinical models of ovarian cancer
A new radioimmunotherapy approach has been shown to successfully eliminate cancer stem cells (CSCs) in preclinical models of ovarian cancer, outperforming the current gold standard. This research, published in the July issue of The Journal of Nuclear Medicine, lays the foundation for further development of radionuclide therapies targeting CSCs, offering renewed hope for more effective treatment options and improved outcomes for patients.
August 1, 2025 — Source or Source

Potential chemo-induced cognitive changes discovered in cancer survivors
Researchers at The City College of New York have linked chemotherapy treatment to lasting cognitive changes in rats—potentially shedding light, for the first time, on cognitive problems some cancer survivors experience long after treatment ends.
August 1, 2025 — Source

Researchers identify protein patterns linked to chemotherapy resistance in bladder cancer
About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy. To better understand why some tumors resist chemotherapy and identify better ways to treat those cancers, researchers at Baylor College of Medicine have conducted a detailed molecular analysis of MIBC tumors.
August 1, 2025 — Source

Scientists reprogram stem cells to create renewable cancer-fighting T cells
In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents. This approach suggests a new way to deliver immunotherapy, acting as an internal factory that produces tumor-targeting immune cells over time and potentially offering longer-lasting protection.
August 1, 2025 — Source

Support for continued use of nasogastric tube after esophageal cancer surgery
In the largest Nordic study to date concerning esophageal cancer surgery, the researchers found clear evidence that decompression with a nasogastric tube is associated with less serious complications. Their results challenge a trend of declining use of the nasogastric tube after major surgical procedures.
August 1, 2025 — Source

Two-drug combo shows durable benefit in advanced kidney cancer
The study reports final clinical data and biomarker analyses from the Phase 3 KEYNOTE-426 trial, which compared the drug combination pembrolizumab plus axitinib versus the single drug sunitinib for patients with previously untreated advanced clear cell renal cell carcinoma, the most common type of kidney cancer.
August 1, 2025 — Source

X-ray and radar technology combined to reduce cancer screening risks
Less radiation exposure during diagnosis and treatment for breast and lung cancer: new Fraunhofer method combines X-ray imaging and radar.
August 1, 2025 — Source

Health — Cancer — July 29th, 2025

A single bout of exercise gives results that could help cancer patients
A single bout of either resistance or high-intensity interval training could help in the cancer battle, new research from Edith Cowan University (ECU) has found.
July 29, 2025 — Source

AI catches one-third of interval breast cancers missed at screening
Interval breast cancers—symptomatic cancers diagnosed within a period between regular screening mammography exams—tend to have poorer outcomes due to their more aggressive biology and rapid growth. DBT, or 3D mammography, can improve visualization of breast lesions and reveal cancers that may be obscured by dense tissue. Because DBT is relatively new as an advanced screening technology, long-term data on patient outcomes are limited in institutions that have not transitioned to DBT until recently.
July 29, 2025 — Source

AI-designed T cell receptor substitutes can accelerate precision cancer immunotherapy
New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased cancer cells, acting like molecular flags that signal immune cells to attack and destroy the threats.
July 29, 2025 — Source

Blood-based tests show promise for colorectal cancer screening but follow-up challenges persist
A study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while blood-based tests offer a more convenient option for colorectal cancer screening, only 49% of patients completed a follow-up colonoscopy within six months, and just 56% did so at any point during the two-year study period. Follow-up colonoscopy is a critical next step to confirm the presence of colorectal cancer or pre-cancer after an abnormal screening result.
July 29, 2025 — Source or Source

Cannabis use disorder triples risk of oral cancer
A recent study by researchers at the University of California San Diego School of Medicine has found that individuals with cannabis use disorder (CUD) are more than three times more likely to develop oral cancer within five years compared to those without CUD. The study highlights the potential long-term health risks associated with problematic cannabis use.
July 29, 2025 — Source

Detecting cancer cells in blood: Microfluidic device captures cancer cells with 90% efficiency
Circulating tumor cells (CTCs) refer to cancer cells that have broken off from a primary tumor. These tumor cells can travel through the blood in the circulatory system and lodge themselves in other organs to cause secondary tumors. Therefore, the detection and subsequent characterization of CTCs from blood can help in the clinical diagnosis and treatment of various cancers. However, the efficient capture of CTCs from blood has been proven to be difficult.
July 29, 2025 — Source

Discovery shows rogue protein fuels Hodgkin lymphoma growth
A new discovery made by researchers from The Australian National University (ANU) could lead to smarter, more effective treatments for Hodgkin lymphoma, a common blood cancer.
July 29, 2025 — Source

Guideline on management of early-stage non-small cell lung cancer released
The American College of Chest Physicians (CHEST) recently released a new clinical guideline on the management of patients with early-stage non-small cell lung cancer (NSCLC). Published in the journal CHEST, the guideline contains 17 evidence-based recommendations to provide a framework for surgeons to implement in their own practice.
July 29, 2025 — Source

Immunotherapy shows promise in changing leukemia's cellular environment
Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment - immunotherapy - may help change the environment where cancer cells live, possibly helping the immune system respond more effectively.
July 29, 2025 — Source or Source

Low rates of isolated locoregional recurrence seen in young women with breast cancer
Laura S. Dominici, M.D., from Brigham and Women's Hospital in Boston, and colleagues examined the long-term incidence of isolated LRR by molecular subtype in a multicenter prospective cohort study of women diagnosed with breast cancer at 40 years or younger from 2006 to 2016.
July 29, 2025 — Source

Microcone-enhanced microfluidic device captures circulating tumor cells efficiently
Circulating tumor cells (CTCs) refer to cancer cells that have broken off from a primary tumor. These tumor cells can travel through the blood in the circulatory system and lodge themselves in other organs to cause secondary tumors. Therefore, the detection and subsequent characterization of CTCs from blood can help in the clinical diagnosis and treatment of various cancers. However, the efficient capture of CTCs from blood has been proven to be difficult.
July 29, 2025 — Source

Nanoimprinted microcone device captures circulating cancer cells with high precision
Researchers utilize engraved polycarbonate sheets and antibody coatings to efficiently capture cancer cells in microchannels.
July 29, 2025 — Source

Oral cancer risk triples among individuals with cannabis use disorder
A recent study by researchers at the University of California San Diego School of Medicine has found that individuals with cannabis use disorder (CUD) are more than three times more likely to develop oral cancer within five years compared to those without CUD. The study highlights the potential long-term health risks associated with problematic cannabis use.
July 29, 2025 — Source

Overcoming Cancer Drug Resistance: A Novel Gold Nanoparticle Therapy
Gold nanoparticles linked to a cancer drug have been shown to improve the killing of ovarian cancer cells, especially in drug-resistant cases.
July 29, 2025 — Source

Rising liver cancer rates highlight need for urgent action worldwide
The majority of liver cancer cases could be prevented by reducing levels of viral hepatitis, alcohol consumption and MASLD (metabolic dysfunction-associated steatotic liver disease -- previously called non-alcoholic fatty liver disease), suggests an analysis as part of The Lancet Commission on liver cancer. The Commission highlights several ways to reduce these risks factors, including increasing the coverage of the hepatitis B vaccine and public health policies targeting obesity and alcohol consumption.
July 29, 2025 — Source

Synergistic effects of radiation and immunotherapy boost anti-tumor immunity
Head and neck squamous cell carcinomas (HNSCC) are a group of cancers that affect cells in and around our mouth and nose. With 890,000 new cases and 450,000 deaths annually, HNSCC accounts for roughly 4.5% of cancer diagnoses and deaths worldwide. Treatment options for HNSCC are very limited, so nearly half of affected patients with HNSCC die from the disease. Current therapies consist of surgery, radiotherapy and chemotherapy, which can be effective but often have limited success and significant side effects.
July 29, 2025 — Source

Health — Cancer — July 27th, 2025

Researcher harnesses AI to transform skin cancer diagnosis in remote areas
A researcher at Heriot-Watt University is harnessing the power of artificial intelligence to give patients living in remote parts access to timely and potentially lifesaving medical diagnoses.
July 27, 2025 — Source

Health — Cancer — July 26th, 2025

Microscopy reveals how Hippo pathway proteins control gene activity in cancer
Melbourne scientists are teasing out how the "Hippo pathway" works at the molecular level, improving understanding of how it exerts control and its potential as a much-needed treatment for the deadly cancer mesothelioma.
July 26, 2025 — Source

Health — Cancer — July 25th, 2025

BATMAN brings T cell receptor therapy out of the shadows
Imagine your immune cells could be modified to attack any kind of cancer. T cell receptor (TCR) therapy has the potential to one day become a universal cancer treatment. But there are risks. Similarities between cancerous and healthy cells can affect the body's immune response, causing T cells to attack unintended targets.
July 25, 2025 — Source

Cellular therapy developed for cancer now being tested in autoimmune disease
Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, has joined with 40 other centers in the U.S. and Europe as a site in one of the first clinical trials testing cellular therapy for autoimmune disease in the U.S.
July 25, 2025 — Source

Chromatin organization linked to p53 tumor suppression mechanism
Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by winding the strings of DNA around protein spools. The protein-DNA complexes are called nucleosomes, and they ensure that DNA is safely stored.
July 25, 2025 — Source

DNA Nanoflower Targets Breast Cancer Cells in Drug Delivery Breakthrough
Scientists have developed a DNA nanoflower that delivers chemotherapy and gene therapy directly to breast cancer cells, boosting effectiveness while reducing side effects in early tests.
July 25, 2025 — Source

Hormone found to suppress immune cells, allowing cancer to evade detection
Researchers at UT Southwestern Medical Center have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body's natural defenses.
July 25, 2025 — Source

Inventor claims bleach injections will destroy cancer tumors
A lack of medical training isn't stopping a man from charging $20,000 for the treatment.
July 25, 2025 — Source

Listen: Some Scientists Speak Out on Deep Cuts to National Cancer Institute, While Others Flee
LISTEN: A National Cancer Institute employee says cuts to research funding and a perceived lack of transparency at the agency are threatening the well-being of cancer patients. A spokesperson for the agency says that's "misleading" — it's working to make sure money is well spent.
July 25, 2025 — Source

New AI tool accelerates mRNA-based treatments for viruses, cancers, genetic disorders
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
July 25, 2025 — Source

New tool maps tumor cell history and location to reveal growth patterns
All life is connected in a vast family tree. Every organism exists in relationship to its ancestors, descendants, and cousins, and the path between any two individuals can be traced. The same is true of cells within organisms—each of the trillions of cells in the human body is produced through successive divisions from a fertilized egg, and can all be related to one another through a cellular family tree. In simpler organisms such as the worm C. elegans, this cellular family tree has been fully mapped, but the cellular family tree of a human is many times larger and more complex.
July 25, 2025 — Source

Researchers identify genetic marker that could guide brain cancer treatment
University of Kentucky Markey Cancer Center researchers have discovered a genetic biomarker that could help identify patients with glioblastoma most likely to benefit from the cancer drug bevacizumab.
July 25, 2025 — Source

Study uncovers how prostate cancer becomes deadly, offers hope for new treatments
In a significant advancement for prostate cancer research, a first-of-its-kind study led by Emory researchers uncovered how the disease transforms into its most lethal form and identified a promising new treatment strategy.
July 25, 2025 — Source

The plant virus that trains your immune system to kill cancer
Plant virus sparks powerful immune attack on cancer—cheap, potent, and headed for clinical trials.
July 25, 2025 — Source or Source

Health — Cancer — July 22nd, 2025

A breath test could help us detect blood cancers
Molecules exhaled in the breath may help detect blood cancer, according to new research from Queen Mary University of London. The findings could enable the development of a blood cancer breathalyzer, providing a rapid, low-cost way to detect disease. This tool may be particularly useful for areas with limited access to specialist equipment or expertise.
July 22, 2025 — Source

Cancer-fighting radioisotope being optimized for therapeutic use
A promising breakthrough in cancer treatment is taking shape at the University of Missouri Research Reactor (MURR), where scientists are developing a powerful radioisotope that could one day precisely target and destroy cancer cells.
July 22, 2025 — Source

CDK4/6 inhibitor combination could overcome drug resistance in advanced prostate cancer
With an estimated 1.5 million new cases and 397,000 deaths worldwide, prostate cancer is the world's second most frequent cancer and the fifth leading cause of cancer death among men in 2022. Hormone therapy based on the inhibition of androgen receptor signaling (ARPi) is the mainstay of treatment for metastatic prostate cancer (mPC). However, cancer drug resistance ultimately arises, highlighting the need for more effective therapeutic strategies
July 22, 2025 — Source

Chemical variations in prostate cancer calcifications analyzed to identify new diagnostic markers
Researchers at Keele University have published the first investigation into the variation in the chemical makeup of calcifications caused by prostate cancer, in the hope of identifying new markers to improve early diagnosis.
July 22, 2025 — Source

Five-year survival in patients with unresectable hepatocellular carcinoma sets milestone
A new exploratory analysis of the HIMALAYA phase III trial involving patients with unresectable hepatocellular carcinoma (uHCC, an advanced liver cancer that could not be treated with surgery or other localized treatments) has shown that one in five (19.6%) participants treated with STRIDE (Single Tremelimumab Regular Interval Durvalumab) a combination of two immunotherapies, remained alive after five years of follow-up versus one in 10 (9.4%) participants treated with sorafenib, a standard treatment for uHCC when the study was designed.
July 22, 2025 — Source

Gene signature predicts aggressive pancreatic cancer before symptoms appear
Precancerous cells must adapt to and overcome cellular stress and inflammation in order to progress and form malignant tumors. Now, researchers at University of California San Diego School of Medicine have identified a link between stress and inflammation and pancreatic ductal adenocarcinoma (PDAC), one of the most aggressive and lethal types of cancer.
July 22, 2025 — Source

New diagnostic breakthrough predicts which head and neck cancer patients can be cured with surgery alone
Researchers from the University of Turku and Turku University Hospital, Finland, led by Docent Sami Ventelä and Professor Jukka Westermarck, have developed a diagnostic tool that can revolutionize the treatment guidance of head and neck squamous cell carcinoma.
July 22, 2025 — Source

New link found between cellular stress and aggressive pancreatic cancer
Precancerous cells must adapt to and overcome cellular stress and inflammation in order to progress and form malignant tumors. Now, researchers at University of California San Diego School of Medicine have identified a link between stress and inflammation and pancreatic ductal adenocarcinoma (PDAC), one of the most aggressive and lethal types of cancer. The findings could serve as an early warning system for the disease, leading to the detection of PDAC before it becomes life-threatening.
July 22, 2025 — Source

Novel analysis identifies differences between benign and cancerous breast calcifications
Benign and cancerous calcium phosphate deposits that may look identical on a mammogram have distinct differences in their structures and formation processes, according to researchers at the University of Illinois Urbana-Champaign and collaborators at the Mayo Clinic and the University of Texas at Austin.
July 22, 2025 — Source

Protein switch behind stubborn lung cancers offers new treatment target
Scientists have uncovered a molecular "on--off" switch that helps lung adenocarcinoma—the most common form of lung cancer—grow and spread. The discovery pinpoints the protein calcyclin‑binding protein (CACYBP) as a key driver of tumor activity and suggests that blocking it could improve outcomes for patients who fail to benefit from current drugs.
July 22, 2025 — Source

Radiation primes the immune system to attack lung tumors resistant to immunotherapy
By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute. The work was supported by the National Institutes of Health.
July 22, 2025 — Source

Suppressing tumor cell stemness might help colon cancer management
Colon cancer remains a major global health concern, ranking third among the most diagnosed cancers and the leading cause of cancer-related death worldwide. One critical factor that makes treating colon cancer challenging is the presence of cancer stem cells.
July 22, 2025 — Source

Toxic fungus from King Tutankhamun's tomb yields cancer-fighting compounds—new study
In November 1922, archaeologist Howard Carter peered through a small hole into the sealed tomb of King Tutankhamun. When asked if he could see anything, he replied: "Yes, wonderful things." Within months, however, Carter's financial backer Lord Carnarvon was dead from a mysterious illness. Over the following years, several other members of the excavation team would meet similar fates, fueling legends of the "pharaoh's curse" that have captivated the public imagination for just over a century.
July 22, 2025 — Source

Understanding thyroid cancer risk, symptoms and treatment
Your thyroid gland may be small, but it plays a big role in keeping your body running. Located at the base of your neck where a bow tie would sit, this butterfly-shaped gland produces hormones that regulate your metabolism, acting like the throttle on an engine for your entire body.
July 22, 2025 — Source

Unique immune cell linked to aggressive leukemia may lead to improved treatment outcomes
A new study by Indiana University School of Medicine researchers has revealed a breakthrough in the fight against acute myeloid leukemia, one of the most aggressive and fatal blood cancers in adults. The discovery of a previously unrecognized immune cell could lead to new therapies that are less treatment-resistant than current options for patients—meaning higher survival rates for people with blood cancers.
July 22, 2025 — Source

Health — Cancer — July 18th, 2025

CRISPR uncovers gene that supercharges vitamin D—and stops tumors in their tracks
Scientists hail key gene with promising 'new avenues' for precision medicine through CRISPR/Cas9.
July 18, 2025 — Source

Cuproptosis offers new hope for treating inflammatory bowel disease and colorectal cancer
Cuproptosis represents a novel mechanism of cell death characterized by intracellular copper ion accumulation. Unlike other cell death pathways, its unique process has garnered significant interest due to its promising applications in treating inflammatory bowel disease (IBD) and colorectal cancer (CRC). Emerging evidence suggests that copper metabolism and cuproptosis may play a dual regulatory role in pathological cellular environments, particularly in modulating oxidative stress responses, metabolic reprogramming, and immunotherapeutic efficacy.
July 18, 2025 — Source< or Source

Gastrointestinal Cancers Are Surging Among Young Americans, and No One Is Quite Sure Why
More people under 50 are being diagnosed with GI cancers, with rates rising particularly rapidly in the U.S.
July 18, 2025 — Source

Human-specific genes that shaped human intelligence may fuel cancer
A study led by Dr. Li Chuanyun from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has revealed how recently evolved human-specific genes—critical for brain development and cognitive abilities—can be hijacked by cancer to drive tumor growth.
July 18, 2025 — Source

New mRNA vaccine strategy awakens immune system to fight cancer
An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.
July 18, 2025 — Source

Novel complex induces immunogenic cancer cell death
Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something is seriously wrong with this type of cell.
July 18, 2025 — Source

Radiotherapy of cancer: Researchers enable better cancer treatment using existing medical equipment
Modern methods of radiotherapy would fight cancer more effectively and safely if treatments could be planned, taking into account the radiation quality of the therapeutic proton beams. An achievement by physicists from the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow brings us closer to this goal.
July 18, 2025 — Source

Researchers unveil drug complex that makes cancer cells self-report to immune system
Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something is seriously wrong with this type of cell. This teaches the immune cells to destroy such cancer cells—even if they are not in the vicinity of the original tumor.
July 18, 2025 — Source

Stevia leaf extract has potential as anticancer treatment, researchers find
Stevia may provide more benefits than as a zero-calorie sugar substitute. When fermented with bacteria isolated from banana leaves, stevia extract kills off pancreatic cancer cells but doesn't harm healthy kidney cells, according to a research team at Hiroshima University.
July 18, 2025 — Source

Study reveals complex patterns of burden and survival among people with digestive system cancers in China
https://www.news-medical.net/news/20250718/New-mRNA-vaccine-strategy-awakens-immune-system-to-fight-cancer.aspx
July 18, 2025 — Source

Health — Cancer — July 17th, 2025

AI and advanced data metrics are forging a new era in cancer research
A new project by a team of researchers across the nation analyzes the ways in which digitized health data, artificial intelligence models and other recent technological advancements have changed how cancers are diagnosed, studied and treated.
July 17, 2025 — Source

Cancer diagnosis does not spur improvements to survivors' diets or eating habits
Researchers from the UC Irvine Joe C. Wen School of Population & Public Health found that a cancer diagnosis did not improve a survivors' diet or create healthier eating habits. The study shows informational deficits during cancer diagnosis treatment planning and a lack of guidance from health care providers.
July 17, 2025 — Source

Children living near oil and gas wells face higher risk of rare leukemia, studies show
Acute lymphocytic leukemia is one of the most commonly diagnosed cancers in children, although it is rare. It begins in the bone marrow and rapidly progresses.
July 17, 2025 — Source

COVID-19 boosters prevent hospitalizations among cancer patients
Vaccine boosters help keep cancer patients from being hospitalized or admitted to intensive care units due to COVID-19, according to a new study led by Cedars-Sinai investigators. Their findings, published in JAMA Oncology, offer real-world evidence to support vaccine recommendations for these patients.
July 17, 2025 — Source

CRISPR-mediated DNA methylation editing regulates inflammation and tumor growth
Genes, fragments of DNA located on our chromosomes, control much of what happens in cells. Each cell activates only the genes it needs, silencing the rest through molecular "switches" present on each gene. However, these switches can sometimes be erroneously activated, leading the cell to behave abnormally and potentially resulting in diseases such as cancer or autoimmune disorders.
July 17, 2025 — Source

FDA-backed metric used to determine effectiveness of rectal cancer drugs may be unreliable, says new study
A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer.
July 17, 2025 — Source

Gaps in skin cancer care for older adults, rural residents, and others highlighted in review
New research from Huntsman Cancer Institute at the University of Utah published in Surgical Clinics of North America shows that some people are more likely to face delays and worse outcomes from dangerous types of skin cancer. These groups include older adults, people living in rural areas, and those who have trouble getting regular medical care.
July 17, 2025 — Source

How metabolic chatter between cells undermines anti-tumor immunity
A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary metabolic processes, program one set of noncancerous cells to manipulate another set of such cells to support their growth and survival.
July 17, 2025 — Source

Literature review reveals global rise in gastrointestinal cancers, with colorectal cancer leading the trend
Early-onset gastrointestinal (GI) cancers are rising at alarming rates worldwide and, in the U.S., are increasing faster than any other type of early-onset cancer, including breast cancer, according to two literature reviews from Dana-Farber Cancer Institute.
July 17, 2025 — Source

Metabolism linked to protective effect of breastfeeding against breast cancer
Breastfeeding is often linked with better health for both mothers and babies, but it does not protect all women against breast cancer. The reason remains unknown. Since breast cancer in young women is on the rise, understanding why breastfeeding is protective in some women but not others is critical.
July 17, 2025 — Source

New dual-drug strategy shows promise against aggressive leukemia
Peter Mac researchers have discovered a powerful new drug combination that could offer hope to children and adults with certain subtypes of acute myeloid leukemia (AML).
July 17, 2025 — Source

New technology successfully monitors cancer progression at the cellular level
Sensome, the pioneer of microsensing technology for real-time, in situ tissue analysis, today announced the publication of a study in Science Advances unveiling an innovative methodology using its technology to noninvasively monitor cell spatiotemporal dynamics involved in cancer progression in a real-time and label-free manner, which can provide new insights for cancer diagnosis and treatment.
July 17, 2025 — Source

Nuclear waste exposure in childhood associated with higher cancer incidence
Living near Coldwater Creek-a Missouri River tributary north of St. Louis that was polluted by nuclear waste from the development of the first atomic bomb-in childhood in the 1940s, '50s, and '60s was associated with an elevated risk of cancer, according to a new study led by Harvard T.H. Chan School of Public Health. The researchers say the findings corroborate health concerns long held by community members.
July 17, 2025 — Source

Scientists zero in on cellular mechanism fueling drug-resistant cancers
The mystery of how cancers build up resistance mechanisms and evade the treatments that should have destroyed them is a hugely pressing question. Overcoming cancer treatment resistance—a phenomenon that contributes to as much as 90% of cancer-related deaths—is among the top missions of 21st century medical research.
July 17, 2025 — Source

Specially engineered antibody delivers RNA therapy to treatment-resistant tumors
A specially engineered antibody capable of delivering RNA therapies to hard-to-reach, treatment-resistant tumors significantly shrank tumor size and improved survival in animal models, according to a study published July 16 in Science Translational Medicine.
July 17, 2025 — Source

Study casts doubt on a widely used shortcut in rectal cancer drug trials
A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer.
July 17, 2025 — Source

Vaccinated women face fewer cervical cancer risks
New data from Denmark shows the HPV vaccine's powerful long-term impact, while also revealing why cervical cancer screening is still essential.
July 17, 2025 — Source

When the stakes are high, do machine learning models make fair decisions?
Machine learning is an integral part of high-stakes decision-making in a broad swath of human-computer interactions. You apply for a job. You submit a loan application. Algorithms determine who advances and who is declined.
July 17, 2025 — Source

Health — Cancer — July 14th, 2025

Anti-nausea medication linked to higher survival rates in women with triple negative breast cancer
A new study has found that a commonly prescribed anti-nausea medication is associated with a better prognosis for women with early-stage breast cancer, particularly triple-negative breast cancer.
July 14, 2025 — Source

EAGLE model predicts key lung cancer mutations from routine biopsy
A new AI tool reads lung cancer biopsy slides in under an hour, accurately predicting mutations and saving patients delays, costs and tissue loss, marking a turning point in precision cancer care.
July 14, 2025 — Source

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation
The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators. The recipients of this prestigious award are outstanding, early-career physician-scientists conducting patient-oriented cancer research at major research centers under the mentorship of the nation's leading scientists and clinicians.
July 14, 2025 — Source

Guideline-based prostate cancer treatment helps most men outlive the disease
Most men who are treated for prostate cancer according to modern guidelines have good survival rates and the majority of these men will die of causes other than prostate cancer. This is revealed in a new study from Uppsala University published in the Journal of the National Comprehensive Cancer Network.
July 14, 2025 — Source

Jack Dorsey's new app tracks your sun exposure
Sun Day is now in beta.
July 14, 2025 — Source or Source

Muscle weakness in cancer survivors may be caused by treatable weakness in blood vessels, says new study
Muscle loss in cancer patients is a major health problem, but the exact causes of how precisely tumors affect muscles remain an active area of research.
July 14, 2025 — Source

New imaging technique monitors protein changes in cancer cells without dyes
Researchers from Helmholtz Munich and the Technical University of Munich have developed a novel method to track cancer treatment responses in individual cells—without the need for dyes or labels.
July 14, 2025 — Source

New immunology-driven radiation therapy techniques showcased at conference
University of Kentucky Markey Cancer Center researcher Weisi Yan, M.D., Ph.D., recently shared his work on radiation therapy at a major international conference, showcasing how new techniques could better protect patients' immune systems while fighting cancer.
July 14, 2025 — Source

New immunotherapy targets leukemia at its root
Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells -- and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival. The findings, published in Nature Communications, offer new hope for treating and preventing cancer.
July 14, 2025 — Source

New label-free imaging tracks cancer treatment in single cells
Mid-infrared optoacoustic microscopy technology enables real-time visualization of protein changes inside living myeloma cells, providing early insights into treatment effectiveness.
July 14, 2025 — Source

New study reveals promising strategy to retrain neutrophils to target breast cancer
A new study conducted by researchers from McGill University, the Lady Davis Institute for Medical Research (LDI) at the Jewish General Hospital, Princess Margaret Cancer Center and MIT has identified a novel approach to combat aggressive breast cancers by retraining neutrophils, the body's first responders, to directly kill tumor cells. This research offers new hope for patients with breast cancers that do not respond well to existing immunotherapies.
July 14, 2025 — Source

Prostate cancer cells evade ferroptosis by accumulating lipid droplets
A new research paper was published in Volume 16 of Oncotarget on June 25, 2025, titled "Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer."
July 14, 2025 — Source

Researchers link CAR-T cell aging to cancer relapse
Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the engineered immune cells age and lose their ability to fight cancer.
July 14, 2025 — Source

Scientists unlock ancient cellular wisdom of brain stem cells, offering hope for brain cancer and degenerative disease
In a landmark discovery, researchers from QIMR Berghofer in collaboration with the Francis Crick Institute, have unlocked the secrets of how brain stem cells enter and exit a resting state called "quiescence"—a process with roots stretching back to the dawn of life.
July 14, 2025 — Source

Viome and Scripps Research join forces to develop at-home RNA test for colon cancer prevention
Viome Life Sciences, the leader in AI-powered, RNA-based diagnostics and precision nutrition and Scripps Research, the leader in accelerating the impact of fundamental research on human health, today announced a strategic partnership to develop and clinically validate the first at-home RNA test designed to detect precancerous colon polyps, enabling early prevention of colorectal cancer.
July 14, 2025 — Source

Health — Cancer — July 12th, 2025

Targeted radiation offers promise in patients with metastasized small cell lung cancer to the brain
A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they experienced positive outcomes that support use of targeted radiation in the future for such patients.
July 12, 2025 — Source

Health — Cancer — July 10th, 2025

A key protein helps liver cancer resist heat-based treatment
A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center may help explain why certain liver tumors return quickly after thermal ablation, a widely used minimally-invasive, image-guided technique that kills cancer cells by applying intense heat through a needle-like probe.
July 10, 2025 — Source

An FDA-approved drug halts Epstein-Barr virus-driven lymphoma by disrupting a key cancer pathway
Scientists at The Wistar Institute have discovered that a class of FDA-approved cancer drugs known as PARP1 inhibitors can effectively combat Epstein-Barr virus (EBV)-driven lymphomas. The findings, published in the Journal of Medical Virology, demonstrate that these drugs, which work by blocking the activity of the PARP1 enzyme, can halt tumor growth by interfering with the EBV's ability to activate key cancer-promoting genes.
July 10, 2025 — Source

Gene-editing platform could boost anti-cancer immune responses
Researchers have developed a new gene-editing platform that will enable safer and more effective T cell--based immunotherapies to treat cancer.
July 10, 2025 — Source

Large language models show promise in predicting liver cancer treatment response
A research team led by Prof. Hai Li from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, has become the first to systematically explore how large language models (LLMs) can assist in predicting liver cancer treatment responses-offering a new path toward AI-powered precision medicine.
July 10, 2025 — Source

Most patients with advanced melanoma remain disease-free 4 years after pre-surgical immunotherapy, study finds
Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive, according to new results from a study led by researchers at The University of Texas MD Anderson Cancer Center.
July 10, 2025 — Source

New research offers reassurance about localized prostate cancer prognosis
New research in JNCCN—Journal of the National Comprehensive Cancer Network finds that for people diagnosed with nonmetastatic low-risk prostate cancer later in life, and treated according to NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines), 90% were likely to survive their cancer for their remaining life-expectancy.
July 10, 2025 — Source

New research uncovers link between cancer pathway and blood-retina barrier function
A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels.
July 10, 2025 — Source

New survival benchmark for patients with advanced biliary tract cancer reached using combination therapy
In a follow-up analysis to the pivotal TOPAZ-1 study, which established the combination therapy of durvalumab (an immunotherapy drug) plus gemcitabine and cisplatin (GemCis, chemotherapy drugs) as the first-line treatment for people with advanced biliary tract cancer (aBTC), researchers have shown that after three years more than twice as many study participants treated with durvalumab plus GemCis had survived compared to those treated with a placebo plus GemCis.
July 10, 2025 — Source

Psychological stress drives ovarian tumor metastasis through NR3C1 and NUPR1
This new article publication from Acta Pharmaceutica Sinica B, discusses how a psychological stress-activated NR3C1/NUPR1 axis promotes ovarian tumor metastasis.
July 10, 2025 — Source

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer
A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights into RTK dependent and independent mechanisms."
July 10, 2025 — Source

Updated NeoVax cancer vaccine shows improved immune response in melanoma trial
Results of a Dana-Farber Cancer Institute-initiated phase 1 clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine called NeoVax^MI is safe, feasible, and improves the vaccine-specific immune response compared to previous trials of the platform.
July 10, 2025 — Source

Vaccines work: Data show real-world evidence of stable protection against HPV-related cervical cancer
Among the more than 100 types of human papillomavirus (HPV), at least 14 are considered as "high-risk" types which can cause (cervical) cancer. After breast cancer, cervical cancer is the most common cancer in Europe among women aged 15--44 years.
July 10, 2025 — Source

Watch: She's at high risk of breast cancer. She moved, and her screening costs soared.
Kelli Reardon undergoes an MRI twice a year to screen for breast cancer, a measure she said she must take to protect her health. Her mother died of the disease at age 48, putting Reardon at higher risk, and Reardon has dense breast tissue, which makes it harder to detect a growth through a mammogram.
July 10, 2025 — Source or Source

Wireless implant delivers chemotherapy deep into tumors without side effects
Researchers have developed a wireless implantable drug delivery system that enables anticancer drugs to penetrate deep into solid tumors—without harming surrounding healthy tissue. The multidisciplinary team, led by experts in materials science, bioelectronics, and pharmaceutical engineering, offers a new strategy to enhance the efficacy of chemotherapy while minimizing side effects.
July 10, 2025 — Source

Health — Cancer — July 7th, 2025

Breast cancer: Treatment decisions on basis of biomarker-based test can be harmful
The German Institute for Quality and Efficiency in Health Care (IQWiG) has examined the pros and cons of biomarker-based tests to inform decisions about adjuvant chemotherapy for patients with a certain type of breast cancer, i.e., first-time, hormone receptor-positive and HER2/neu-negative breast cancer.
July 7, 2025 — Source

Common medication for lung cancer symptoms found to limit immunotherapy effectiveness
Corticosteroids, a commonly prescribed medication to alleviate cancer-related symptoms for non-small cell lung cancer patients treated with immunotherapy, are the main reason certain immunotherapies may fail in treating the disease, according to new research by Keck Medicine of USC.
July 7, 2025 — Source

Corticosteroids may reduce effectiveness of immunotherapy in lung cancer
Corticosteroids, a commonly prescribed medication to alleviate cancer-related symptoms for non-small cell lung cancer patients treated with immunotherapy, are the main reason certain immunotherapies may fail in treating the disease, according to new research by Keck Medicine of USC.
July 7, 2025 — Source

Excess weight linked to breast cancer risk in postmenopausal women with cardiovascular disease
New research reveals that excess weight is linked to an especially high risk of developing breast cancer in postmenopausal women with cardiovascular disease. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.
July 7, 2025 — Source

How body mass index affects breast cancer risk in postmenopausal women with and without cardiovascular disease
New research reveals that excess weight is linked to an especially high risk of developing breast cancer in postmenopausal women with cardiovascular disease.
July 7, 2025 — Source

Metabolic enzyme PHGDH found to play a surprising role in breast cancer immunity
Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor progression and dampening immune responses. This shift is influenced by the tumor microenvironment, where limited nutrients and oxygen force immune cells into a metabolic tug-of-war. One pathway under scrutiny is serine biosynthesis, regulated by the enzyme PHGDH.
July 7, 2025 — Source

Precision medicine approach identifies promising ovarian cancer treatment
A pairing of two experimental drugs inhibits tumor growth and blocks drug-induced resistance in ovarian cancer, according to a preclinical study led by Weill Cornell Medicine investigators.
July 7, 2025 — Source

Reversing immune fatigue offers new hope for cancer treatment
CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter. Prolonged exposure to antigens, lack of co-stimulatory signals, and a barrage of suppressive molecules push them into an exhausted state. Like batteries drained of power, they stop proliferating, reduce cytokine production, and overexpress inhibitory receptors like PD-1, CTLA-4, and LAG-3. Worse still, their mitochondria and metabolism break down, leaving them energy-starved. Due to these compounded dysfunctions, many cancer treatments struggle to sustain durable responses.
July 7, 2025 — Source

Study finds higher risk of death from lymphoma and infections in rare skin cancer
A new study by researchers at Karolinska Institutet and Karolinska University Hospital shows that patients diagnosed with the rare skin cancers mycosis fungoides and Sezary syndrome face a significantly higher risk of dying from lymphoma and infections compared to the general population.
July 7, 2025 — Source

Targeted Nanozyme Therapy for HER2 Cancer
Researchers have developed a new nanomaterial platform that combines nanozymes with antibody targeting to improve the precision and effectiveness of treatment in HER2-positive cancer models.
July 7, 2025 — Source

Treating a common bacteria could reduce gastric cancer cases worldwide
Up to 76% of those cases may be attributable to Helicobacter pylori, a common bacterium found in the stomach. The authors call for greater investment in the prevention of gastric cancer, particularly through population-wide H. pylori screen-and-treat programs, to reduce the burden of gastric cancer worldwide.
July 7, 2025 — Source

Health — Cancer — July 2nd, 2025

Air pollution may contribute to development of lung cancer in never-smokers
A new study reveals that air pollution, traditional herbal medicines and other environmental exposures are linked to genetic mutations that may contribute to the development of lung cancer in people with no or hardly any history of smoking.
July 2, 2025 — Source

Alzheimer's-related protein found to drive lung cancer spread to brain
Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer's disease helps lung cancer spread to the brain—a discovery that offers hope that existing Alzheimer's drugs could be repurposed in preventing cancer's spread.
July 2, 2025 — Source

Antibody-cancer drug combo shows promise against aggressive lymphoma
Cancer-hunting antibodies coupled with a natural compound found in soil microbes proved a powerful combination against an aggressive type of blood cancer, according to a new study from scientists at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology.
July 2, 2025 — Source

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer
Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily to other parts of the body. Such epithelial-to-mesenchymal plasticity also makes the cancer cells resistant to elimination by anticancer therapies.
July 2, 2025 — Source

Benzaldehyde blocks pancreatic cancer spread by disrupting key protein interactions
Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily to other parts of the body. Such epithelial-to-mesenchymal plasticity also makes the cancer cells resistant to elimination by anticancer therapies.
July 2, 2025 — Source

Bioengineered hydrogel mimics tumor environment to preserve live tissues for longer
A new hydrogel-based platform to preserve live patient-derived tumor tissues in the lab could pave the way for faster, more accurate testing of cancer treatments for patients with peritoneal metastases, a hard-to-treat and often deadly form of abdominal and pelvic cancers.
July 2, 2025 — Source

Considerable proportion of colonoscopy bowel preparation claims involve cost-sharing
Eric D. Shah, M.D., from the University of Michigan in Ann Arbor, and colleagues conducted a cross-sectional analysis to examine out-of-pocket costs for bowel preparations among patients enrolled in commercial and Medicare Part D plans undergoing screening colonoscopy, focusing on differences across high- and low-volume bowel preparation categories.
July 2, 2025 — Source

Coupling two methods opens up new possibilities in early detection of colorectal cancer
The number of colorectal cancer cases in people under 50 is rising worldwide, especially in high-income countries. Possible causes include Western diets, obesity, lack of exercise, and the use of antibiotics, especially in early life and adolescence.
July 2, 2025 — Source

Engineered cell cross-talk unlocks CAR-T potential against glioblastoma
A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the effectiveness of chimeric antigen receptor (CAR) T cell therapy against glioblastoma, one of the most lethal and treatment-resistant brain tumors.
July 2, 2025 — Source

Flipping alkenes for more effective cancer drugs with fewer harmful side effects
For the first time, chemists have discovered a unique way to control and modify a type of compound widely used in medicines, including a drug used to treat breast cancer.
July 2, 2025 — Source

Leukemia-on-a-chip offers breakthrough in personalized cancer treatment
A team of researchers led by NYU Tandon School of Engineering's Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients.
July 2, 2025 — Source

New genetic marker linked to improved survival with immunotherapy in ovarian and other cancers
Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have improved survival following immunotherapy compared to patients without these mutations, according to researchers from The University of Texas MD Anderson Cancer Center.
July 2, 2025 — Source

New strategy enhances immunotherapy effectiveness against glioblastoma by utilizing gut microbes
Advanced treatments, known as immunotherapies that activate T cells—our body's immune cells—to eliminate cancer cells, have shown limited efficacy as standalone therapies for glioblastoma, the most lethal form of brain tumor. This is due to their minimal response to glioblastoma and high resistance to treatment.
July 2, 2025 — Source

NIH Scientists Link Air Pollution and Lung Cancer Mutations in Non-Smokers
Research from the NIH's National Cancer Institute, an agency beleaguered by funding cuts and censorship, finds that particulate matter pollution impacts lung cancer at the DNA level.
July 2, 2025 — Source or Source

Older women face increased risk of HPV-related cervical cancer
But most guidelines currently recommend discontinuing screening for the disease in women aged 65+ if they have had previously normal smear tests. Yet global cases of cervical cancer have been rising among women in this age group, prompting the researchers to call for a policy rethink.
July 2, 2025 — Source

Scientists reveal how chemotherapy causes genetic damage in healthy blood
For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.
July 2, 2025 — Source

Survey finds some confusion over mammogram guidelines
Mammograms can find cancer early before symptoms appear. Regular screening decreases the risk of dying from breast cancer. But a recent survey question by the Annenberg Public Policy Center shows that some Americans appear to be confused about when women with an average risk of breast cancer should begin a regimen of regular mammograms.
July 2, 2025 — Source

Thresholds for preop serum calcitonin predict lymph node metastasis in thyroid cancer
Yuxin Du, M.D., from the Fudan University Shanghai Cancer Center, and colleagues updated the optimal thresholds of basal serum calcitonin levels for predicting the extent of LNM in a retrospective cohort study. Five hundred nine patients with initially treated MTC who had their preoperative basal calcitonin levels tested using electrochemiluminescence or chemiluminescence between 2011 and 2024 were included and were randomly divided into a training cohort and validation cohort (2:1 ratio).
July 2, 2025 — Source

Health — Children & Kids — July 2nd, 2025

Antimicrobial common in everyday items linked to allergic conditions in children
Triclosan is an antimicrobial chemical that was for decades added to everyday items like soap, toothpaste, cosmetics and even kitchen utensils and athletic wear, until concerns about potential health risks led manufacturers to phase it out of some products.
July 2, 2025 — Source

Myth busted: Study finds men don't sleep through baby cries after all
A new study from Aarhus University challenges the widespread belief that women are naturally "hardwired" to wake up more easily to a crying baby than men.
July 2, 2025 — Source

Peer influence drives youth vaping epidemic, researchers find
Young people with friends who vape are 15 times more likely to use e-cigarettes, and more adolescents are turning to illicit cannabis products, University of Queensland research has found.
July 2, 2025 — Source

Resilience emerges a key factor in reducing emotional distress in girls with juvenile fibromyalgia
Juvenile fibromyalgia is a chronic pain disorder that mainly affects adolescent girls. A study led by the University of Barcelona shows that resilience—the ability to cope adaptively with adversity—does not reduce the physical symptoms of this chronic disease, but could act as a protective factor at the emotional and brain level.
July 2, 2025 — Source

Sensory-motor activity protocol increases reading speed of children with dyslexia
After following a protocol of sensory-motor activities with cognitive engagement for two months, eleven children aged 10 to 12 who were diagnosed with dyslexia showed improvement in reading speed. This initiative combined recreational activities that incorporated motor and social skills, demonstrating promise in improving children's reading performance.
July 2, 2025 — Source

Support networks may be missing link for college students who seek help for excessive drinking
College students who want help overcoming high-risk drinking could benefit from a two-pronged approach that combines an individual-focused psychological theory with social network analysis.
July 2, 2025 — Source

Health — Cancer — June 30th, 2025

AI model spots gastric cancer on routine CT scans with high accuracy, outperforming radiologists
A collaboration of leading Chinese research institutions has developed an artificial intelligence-based method called GRAPE, demonstrating high accuracy in detecting gastric cancer from routine noncontrast CT scans.
June 30, 2025 — Source

AI models could spot pancreatic cancer at an early stage and predict prognosis
Oncologists utilizing artificial intelligence (AI) in their tests to spot pancreatic cancer at an early stage can also gain an overall picture of how the deadly disease is bound to develop, scientists from the University of Sharjah have revealed in a new study.
June 30, 2025 — Source

FAU researchers secure key grants to target new gene in the fight against glioblastoma
Florida Atlantic University researchers have secured two key grants to investigate targeting a gene for the first time as a new approach to treat glioblastoma, a very aggressive and fast-growing type of brain cancer.
June 30, 2025 — Source

IncRNA's role in triple-negative breast cancer provides potential inroads to much-needed therapies
Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable. The exception is a particularly aggressive variant known as triple-negative breast cancer (TNBC). It accounts for 10% to 15% of all breast cancer cases. It disproportionately affects younger and African American women.
June 30, 2025 — Source

Mucoadhesive nanoplatforms enable precision imaging of bladder cancer
A mucoadhesive nanoplatform improves bladder cancer imaging by selectively targeting tumors and enhancing visualization for more precise non-invasive diagnosis.
June 30, 2025 — Source

Researcher publishes three studies advancing treatment for rare and aggressive lymphoma
Three major Mount Sinai research studies offer new hope for patients facing chronic lymphocytic leukemia (CLL), a rare type of blood cancer. The studies were led by Adam Kittai, MD, Associate Professor of Medicine (Hematology and Medical Oncology) at the Icahn School of Medicine at Mount Sinai and the Director of Mount Sinai's CLL Program. As one of the world's leading experts on Richter transformation, Dr. Kittai aims to increase awareness about Mount Sinai's CLL program and welcome patients in need of a second opinion.
June 30, 2025 — Source

Scientists discover 'off switch' enzyme that could stop heart disease and diabetes
UTA research could help restore proper cholesterol levels, stopping many diseases in their tracks.
June 30, 2025 — Source

Terbium's green glow: A simple sensor for liver cancer
Researchers at the Indian Institute of Science (IISc) have developed a unique luminescent probe that uses terbium, a rare earth metal, to sense the presence of an enzyme called &beta-glucuronidase, which can potentially aid in the detection of liver cancer.
June 30, 2025 — Source

This AI tracks lung tumors as you breathe — and it might save lives
New deep learning tool may boost precision and consistency for cancer treatment
June 30, 2025 — Source or Source

Health — Cancer — June 29th, 2025

Lung cancer screening is about to start. What you need to know if you smoke or have quit
From July, eligible Australians will be screened for lung cancer as part of the nation's first new cancer screening program for almost 20 years.
June 29, 2025 — Source

Notorious Fungus Blamed for 'Mummy's Curse' Is Now a Promising Cancer Treatment
A dreaded fungus known to inhabit tombs has been reconstituted as a treatment for leukemia and is performing as effectively as some FDA-approved drugs.
June 29, 2025 — Source

Health — Cancer — June 25th, 2025

80% of colorectal cancers resist immunotherapy—this DNA treatment could help
A University of Alberta research team has identified a DNA structure that activates the immune system in cancer cells that are usually resistant to immunotherapy, offering hope of new, more effective treatments for colorectal and other cancers.
June 25, 2025 — Source

Botox mitigates debilitating dry mouth in prostate cancer patients receiving radiopharmaceutical therapy
A dual-protective approach using botulinum toxin (Botox) alongside an anti-nausea patch significantly reduces salivary gland toxicity in patients with metastatic prostate cancer undergoing PSMA-targeted radiopharmaceutical therapy.
June 25, 2025 — Source

How your gut bacteria could help detect pancreatic cancer early
Whether you had breakfast this morning or not, your pancreas is working quietly behind the scenes. This vital organ produces the enzymes that help digest your food and the hormones that regulate your metabolism. But when something goes wrong with your pancreas, the consequences can be devastating.
June 25, 2025 — Source

Immune cells promoting tumor growth? How dying cancer cells turn their enemies into allies
Scientists at Nagoya University in Japan studied what happens when macrophages—a type of immune cell—encounter dying cancer cells in tumors and discovered a mechanism that accelerates tumor growth. When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are dying.
June 25, 2025 — Source

Inside the tumor: AI cracks five hidden cell types to stop cancer's comeback
Scientists have developed a new AI tool which could be integrated into cancer diagnostics to better inform treatment.
June 25, 2025 — Source

Key proteins linked to brain tumor growth offer hope for personalized therapies
Researchers from the University of Plymouth have identified proteins that fuel the growth of the most common type of brain tumor, a discovery that could ultimately lead to less invasive treatments for patients.
June 25, 2025 — Source

Nanobody hitchhikers boost immunotherapy potency in cancer treatment
Researchers led by John T. Wilson, Vanderbilt University associate professor of chemical and biomolecular engineering and biomedical engineering, have developed a new approach using a molecularly designed nanobody platform that seeks to make immunotherapy more effective in the treatment of cancer.
June 25, 2025 — Source

New insights into the role of diet and microbiome in gastric cancer
Gastric cancer (GC), once primarily seen in older adults, is on the rise among younger individuals in developed countries. In a recent review, researchers from The Chinese University of Hong Kong analyzed how diet, gastric microbes, and their metabolites influence the risk of GC, highlighting harmful and protective microbial species and dietary patterns. This study serves as a roadmap for GC research and points toward personalized dietary and microbiome-based strategies for GC prevention.
June 25, 2025 — Source

Researchers capture first signs of ovarian cancer risk
Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means it has spread to other parts of the body.
June 25, 2025 — Source

Researchers develop high-performance, open-source AI for breast cancer detection
In a major breakthrough, a team of researchers from The City College of New York and Memorial Sloan Kettering Cancer Center (MSKCC) has developed a new AI model that can detect breast cancer in MRI images and pinpoint the location of tumors.
June 25, 2025 — Source

Role of tumor microenvironment in nasopharyngeal carcinoma progression uncovered
A study led by clinician-scientists and researchers at the National Cancer Centre Singapore (NCCS) has found that the tumor immune microenvironment (TIME) plays a critical role in the progression of nasopharyngeal carcinoma (NPC) commonly known as nose cancer. These insights are paving the way for precision oncology approaches, some of which are currently used in clinical trials at NCCS.
June 25, 2025 — Source

Western Health to try out new AI to tailor chemo dosing
The digital tool calculates dosing based on body composition.
June 25, 2025 — Source

Health — Cancer — June 22nd, 2025

Team discovers how tiny parts of cells stay organized, adding new insights for blocking cancer growth
A team of international researchers led by scientists at City of Hope provides the most thorough account yet of an elusive target for cancer treatment. Published in Science Advances, the study suggests a complex signaling process involving paxillin, a focal adhesion protein that acts as a hub to connect with other proteins, may be vulnerable to therapy despite its fluid state.
June 22, 2025 — Source

Health — Cancer — June 21st, 2025

Electromagnetic navigation bronchoscopy emerges as an effective alternative for lung nodule localization
Electromagnetic navigation bronchoscopy emerges as an effective alternative for lung nodule localization
June 21, 2025 — Source

FDA approves once-monthly Andembry for hereditary angioedema
The U.S. Food and Drug Administration has approved Andembry (garadacimab-gxii) as the only treatment targeting factor XIIa for prophylactic use to prevent attacks of hereditary angioedema (HAE).
June 21, 2025 — Source

Genetics of cardiomyopathy risk in childhood cancer survivors differ by age of onset, study shows
The relationship between genetic variants and the risk of late-onset cardiomyopathy remains poorly understood in survivors of childhood cancer despite being otherwise well established. Scientists from St. Jude Children's Research Hospital have helped address this gap, assessing whether variant trends seen in the general population also apply to late-onset cardiomyopathy in five-year survivors of childhood cancer.
June 21, 2025 — Source

Healthy gut microbiome before chemo could help protect breast cancer patients against cardiotoxicity
New research suggests that a healthy microbiome before chemotherapy could help protect breast cancer patients against heart damage, or cardiotoxicity, as a result of cancer therapy.
June 21, 2025 — Source

Health — Cancer — June 20th, 2025

Breast cancer patients' microbiome may hold key to avoiding damaging heart side-effects of cancer therapies
New research suggests that a healthy microbiome before chemotherapy could help protect breast cancer patients against heart damage, or cardiotoxicity, as a result of cancer therapy.
June 20, 2025 — Source

Immune changes predict heart risks in cancer patients on checkpoint inhibitors
New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint inhibitors.
June 20, 2025 — Source or Source

New clinical trial tests non-invasive method to protect hearts during chemotherapy
A simple intervention, similar to the tension applied to the arm during a blood pressure reading, is being tested in a Phase II clinical trial to see if it can help cancer patients treated with common chemotherapy drugs, called anthracyclines, avoid heart failure.
June 20, 2025 — Source

New nanoparticle system improves drug delivery for cancer treatment
Scientists at Xi'an Jiaotong-Liverpool University (XJTLU) and Nanjing University in China have developed a new drug delivery system that could improve how treatments of cancers and other diseases are delivered. Their study, published in the journal ACS Applied Materials & Interfaces, describes a new type of nanoparticle made by combining a widely used medical polymer with a natural blood protein. These particles can carry much larger amounts of disease-fighting drugs and remain stable much longer than current nanoparticle systems.
June 20, 2025 — Source

Risk prediction model offers personalized outlook for early-stage Hodgkin's lymphoma
Researchers from RWJBarnabas Health and Rutgers Cancer Institute, New Jersey's only National Cancer Institute-designated Comprehensive Cancer Center, as well as Tufts Medical Center and The University of Manchester, have developed and validated the first individualized risk prediction model for adults diagnosed with early-stage classic Hodgkin's lymphoma.
June 20, 2025 — Source

Scientists develop tool to predict bowel cancer drug resistance
Scientists have developed a tool that can predict how bowel cancer adapts to treatment -- helping researchers to design new personalized drugs that will keep patients living well for longer.
June 20, 2025 — Source

Scientists find new way to predict how bowel cancer drugs will stop working—paving way for smarter treatments
Scientists have developed a tool that can predict how bowel cancer adapts to treatment—helping researchers to design new personalized drugs that will keep patients living well for longer.
June 20, 2025 — Source

Troubling Case Links Vaping to Aggressive Lung Cancer
A New Jersey man's unusual lung cancer may have been sparked by his decade-plus history of vaping.
June 20, 2025 — Source

Health — Cancer — June 18th, 2025

B-cell lymphoma study identifies traits tied to greatest benefit from CD19 CAR T cell therapy
In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three subgroups of patients with large B-cell lymphoma (LBCL) who have different levels of benefit from CD19 chimeric antigen receptor (CAR) T cell therapy.
June 18, 2025 — Source

Blocking a key enzyme could rewire cancer cells and suppress tumor growth
Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.
June 18, 2025 — Source

Designing an AI tool for automated, customized nutrition advice for cancer patients
Research shows that good nutrition can contribute to the overall health and well‐being of cancer patients. However, personalized dietary advice can be hard to access and is not often covered by health insurance.
June 18, 2025 — Source

Engineered enzyme enables detailed mapping of tRNA changes in tumor cells
The method—dubbed "MapID-tRNA-seq"—allowed researchers to examine all tRNAs and their changes within human cells at once, according to the report. The study focused on transfer RNAs, or tRNAs, which ferry protein building blocks inside of cells, making them biologically essential. Dysregulated tRNAs are frequently involved in human diseases.
June 18, 2025 — Source

High-speed AFM and 3D modelling help towards understanding the dynamics of a protein implicated in several cancers
New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques.
June 18, 2025 — Source

Inhibiting RNA Polymerase 1 suppresses tumor growth in hard-to-treat cancers
Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.
June 18, 2025 — Source

Large language models show promise in predicting liver cancer treatment outcomes
A research team led by Prof. Li Hai from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has become the first to systematically explore how large language models (LLMs) can assist in predicting liver cancer treatment responses—offering a new path toward AI-powered precision medicine.
June 18, 2025 — Source

Novel fusion gene leads to diagnosis of adenoid cystic carcinoma
A paper published by researchers at Fox Chase Cancer Center highlights the case of a patient who was diagnosed with adenoid cystic carcinoma (ACC) after a molecular panel identified the presence of an atypical fusion gene.
June 18, 2025 — Source

Novel Nanoplatform Overcomes Treatment Resistance in Bladder Cancer
A publication in Nano-Micro Letters reveals a significant breakthrough in bladder cancer treatment. Researchers from the University of California, Davis, have developed a multifunctional nanoparticle platform that integrates phototherapy and real-time imaging capabilities.
June 18, 2025 — Source

Organ-sculpting cells may hold clues to how cancer spreads
A new study by scientists at the University of North Carolina at Chapel Hill reveals that the cells shaping our organs may be far more mobile and coordinated than once believed.
June 18, 2025 — Source

Targeting NK cells could open the door to more effective immunotherapy in resistant tumors
Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered that "natural killer" cells (NK), a type of immune cell, may actually be hindering the immune system's ability to attack tumors in patients who don't respond to immune checkpoint blockade therapies (ICB), a form of immune therapy.
June 18, 2025 — Source

The family of molecules that could help diagnose—and treat—breast cancer
Proteoglycans are large molecules that are important for tissues all over the body. For example, they play key roles in the development of cartilage and blood vessels, and they can also protect against inflammation and infection. But their role in cancer is less clear: while some proteoglycans protect against cancer, others can promote tumor growth.
June 18, 2025 — Source

Health — Cancer — June 16th, 2025

AI model achieves high accuracy for liver tumor segmentation
Liver cancer is the sixth most common cancer globally and a leading cause of cancer-related deaths. Accurate segmentation of liver tumors is a crucial step for the management of the disease, but manual segmentation by radiologists is labor-intensive and often results in variations based on expertise.
June 16, 2025 — Source

Cancer before 40: Eexpert shares 3 topics that younger patients often want to discuss
Dr. Allison Rosenthal's experience facing a leukemia diagnosis while in medical school inspired her to pursue a career fighting cancer. It also gave her insight into aspects of life with cancer for people under 40. Now, Dr. Rosenthal is among the leaders of an effort at Mayo Clinic Comprehensive Cancer Center to help younger adults and older teens receive age-appropriate care and support. In this expert alert, Dr. Rosenthal shares three topics that younger people with cancer often want to discuss with their healthcare teams.
June 16, 2025 — Source

Enzyme inhibitor strategy converts neuroblastoma cells into healthy neurons in mice
Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant enzyme inhibitors, they have converted cancer cells in mice into healthy nerve cells.
June 16, 2025 — Source

Minutes instead of months: Algorithm rapidly identifies cell types to match patients with effective cancer therapies
Researchers at VCU Massey Comprehensive Cancer Center have developed a novel algorithm that could provide a revolutionary tool for determining the best options for patients—both in the treatment of cancer and in the prescription of medicines.
June 16, 2025 — Source

More young women are getting breast cancer—why?
At some point in their lifetimes, approximately one out of every eight women in the United States will be diagnosed with breast cancer. That estimate from the American Cancer Society becomes even more troubling when considering that the rate of breast cancer incidence continues to climb, rising around 1% every year from 2012--2021.
June 16, 2025 — Source

mpXsn method reveals eight novel enzymes for accelerated cancer drug production
Stanford University researchers report the discovery of eight previously unknown genes that, when expressed in tobacco leaves, reconstitute the Taxol precursor baccatin III at levels matching its natural abundance in yew needles. The find could accelerate the manufacture of a much-needed cancer drug.
June 16, 2025 — Source

Nanoneedle patch offers painless alternative to traditional cancer biopsies
A patch containing tens of millions of microscopic nanoneedles could soon replace traditional biopsies, scientists have found. The patch offers a painless and less invasive alternative for millions of patients worldwide who undergo biopsies each year to detect and monitor diseases like cancer and Alzheimer's.
June 16, 2025 — Source or Source

New development in stem cell transplant for blood cancers set to change 40 years of standard practice
Australian researchers have demonstrated that the use of a new, less toxic drug combination after stem cell transplants for leukemia significantly improves patient outcomes post-transplant, reducing the risk of the life-threatening complication of graft versus host disease (GVHD).
June 16, 2025 — Source

Researchers identify a new treatment strategy for neuroblastoma
Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant enzyme inhibitors, they have converted cancer cells in mice into healthy nerve cells.
June 16, 2025 — Source

Single psilocybin trip delivers two years of depression relief for cancer patients
Phase 2 trial reveals that a single dose of psilocybin offers long-term relief from symptoms of depression and anxiety.
June 16, 2025 — Source or Source

Specialized cancer navigation initiative launched to meet unique needs of firefighters
Dana-Farber Cancer Institute is launching Direct Connect for Firefighters, a specialized cancer navigation initiative to meet the unique needs of firefighters-a group at higher risk for cancer due to occupational hazards. The program will now be offered to firefighter organizations around the country, expanding Dana-Farber's existing Direct Connect program.
June 16, 2025 — Source

What dinosaur fossils could teach us about cancer
When you think of dinosaurs, you might imagine towering predators or gentle giants roaming prehistoric landscapes. But what if these ancient creatures could teach us about one of humanity's most persistent challenges: cancer?
June 16, 2025 — Source

Health — Cancer — June 13th, 2025

A new AI algorithm is working to get chemotherapy dosing right
Chemotherapy is a vital treatment for people with all forms of cancer. It's a process that uses drugs designed to kill, damage or slow the spread of cancer cells, preventing them from growing and dividing.
June 13, 2025 — Source

A polymeric package deal: Diagnosing and treating breast cancer with a single nanoparticle complex
The drug pipeline—the process through which a potential new drug gets discovered, tested, approved, and marketed—is a notoriously long and arduous process, and even the most promising drugs can languish or die on the road to the clinic.
June 13, 2025 — Source

AI tool analyzes blood DNA fragments for faster, affordable cancer monitoring
Scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new artificial intelligence (AI)-based method called "Fragle" that makes tracking cancer easier and faster using blood tests.
June 13, 2025 — Source

Blocking CD200R1 protein offers new strategy for treatment-resistant blood cancers
Immunotherapy has revolutionized cancer treatment by mobilizing the immune system to attack tumor cells. Major advances, such as immune checkpoint inhibitors (notably against the PD-1 protein), have produced impressive results against certain types of cancer, including melanoma and kidney cancer.
June 13, 2025 — Source

Boosting CAR T cell survival to improve solid tumor therapy
Marcela Maus, MD, PhD, director of the Cellular Immunotherapy Program and the Paula J. O'Keeffe Endowed Chair of the Mass General Cancer Center, is senior author and Stefanie Bailey, PhD, Hana Takei, and Giulia Escobar, PhD of the Krantz Family Center for Cancer Research at Massachusetts General Hospital are co-lead authors of a paper published in Science Translational Medicine, "IFN-g-resistant CD28 CAR-T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models."
June 13, 2025 — Source

Breast cancer patients with BRCA mutations and textured implants found to have increased risk of rare lymphoma
Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more likely to develop breast-implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare T-cell lymphoma, compared to similar women without these genetic mutations, according to a study published today in Blood Advances.
June 13, 2025 — Source

Experimental model for myelodysplastic syndromes uncovers genetic alterations to improve characterization
Myelodysplastic syndromes (MDS) are a group of disorders that typically arise in adulthood, especially after the age of 70, and their five-year survival rate is around 30%. MDS are characterized by defective maturation of blood cells in the bone marrow, leading to a range of health problems such as fatigue and recurrent infections. Without appropriate treatment, they may progress to acute myeloid leukemia, a much more severe disease.
June 13, 2025 — Source

Mapping genetic activity offers new clues for personalized cancer treatment
City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment. The leading-edge brain cancer research provides foundational knowledge that one day will improve the practice of precision medicine and allow oncologists to deliver more personalized therapies to cancer patients.
June 13, 2025 — Source

New drug combination shows high remission rates in acute myeloid leukemia
A combination therapy that adds a recently approved drug to the current standard of care for newly diagnosed acute myeloid leukemia (AML) showed high rates of complete remission in an early-phase clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and 11 other sites nationwide.
June 13, 2025 — Source

New PET imaging approach provides precise mapping of nasopharyngeal cancer biomarker
A novel immuno-PET/CT imaging technique has identified and validated a potent biomarker for nasopharyngeal cancer (NPC). The biomarker, CD70, is highly and constantly expressed in NPCs, and CD70-targeted immuno-PET/CT has proven effective in accurately detecting primary and metastatic NPC lesions.
June 13, 2025 — Source

Potential anti-breast cancer drug identified
A surgeon can excise breast cancer from the body, but even the most skilled scalpel may not be able to remove every cell—especially when the cells have spread from the original disease site elsewhere in the body.
June 13, 2025 — Source

Preventing stalling to improve CAR-T cells' efficacy against tumors
Chimeric antigen receptor (CAR)-T cells are a promising cancer therapy that are made from the patient's own T cells, which are reprogrammed to fight their cancer. One of the limitations of CAR-T cell therapy is the ability of these cells to survive long enough to target the entire tumor.
June 13, 2025 — Source

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse
In this case report, corresponding author Naina Kumar from the All India Institute of Medical Sciences and team describe a rare ovarian tumor in a 70-year-old postmenopausal woman. The tumor was found incidentally during surgery for pelvic organ prolapse. This unusual finding demonstrates the importance of careful tissue evaluation during routine surgeries, especially in older women who may show no symptoms of ovarian disease.
June 13, 2025 — Source

Repurposed cancer drugs shown to promote stroke recovery and limit brain damage
Stroke remains one of the leading causes of death, disability, increased economic burden and decreased quality of life around the world. Current stroke therapies are time-limited and largely focused on restoring blood flow, and there are few which address the secondary wave of inflammation that causes further injury in the hours and days after stroke.
June 13, 2025 — Source

Scientists develop a foundational map of tumor cells for personalized brain cancer treatments
City of Hope researchers have co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment. The brain cancer research provides foundational knowledge that could one day improve the practice of precision medicine and allow oncologists to deliver more personalized therapies to cancer patients.
June 13, 2025 — Source

Health — Cancer — June 9th, 2025

Celebrity diagnoses underscore rising breast cancer rates in young women
More young women in the United States are being diagnosed with breast cancer and several celebrities have helped raise awareness by sharing their stories.
June 9, 2025 — Source

CDK12 gene inactivation: Study defines key driver of aggressive ovarian cancer
A new study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer—and offers a potential pathway for new treatments.
June 9, 2025 — Source

Could electric fields supercharge immune attack on the deadliest form of brain cancer?
A new study led by Keck Medicine of USC researchers may have uncovered an effective combination therapy for glioblastoma, a brain tumor diagnosis with few available effective treatments. According to the National Brain Tumor Society, the average survival for patients diagnosed with glioblastoma is eight months.
June 9, 2025 — Source

Ending unnecessary cancer screenings can take over a decade
Stopping the widespread use of unnecessary, potentially even harmful, cancer screenings can take up to 13 years and potentially even longer after new guidelines are put in place, according to a new study.
June 9, 2025 — Source

Exercise during chemotherapy may help immune cells fight cancer
Exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumors, according to a first-of-its-kind pilot study from the University of Surrey and Royal Surrey NHS Foundation Trust.
June 9, 2025 — Source

FDA authorizes first AI platform for breast cancer prediction
The U.S. Food and Drug Administration has granted de novo authorization to CLAIRITY BREAST, a first-in-class, image-based platform that can help predict a woman's risk for breast cancer.
June 9, 2025 — Source

Giving doctors an AI-powered head start on skin cancer
Detection of melanoma and a range of other skin diseases will be faster and more accurate with a new AI-powered tool that analyzes multiple imaging types simultaneously, developed by an international team of researchers led by Monash University.
June 9, 2025 — Source

Patients are opting in for 10 years of breast cancer treatment
As recommendations suggest extending hormone-based breast cancer treatment to 10 years for some patients, a new study sheds light on whether patients are opting for it.
June 9, 2025 — Source

Protein pivotal for B-cell cancers gets a closer look
Using a modern imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have determined the structure of a protein called midnolin that's crucial to the survival of malignant cells in some leukemias, lymphomas, and multiple myelomas. Their findings, published in PNAS, provide insight into how this protein functions in cells and could inform the design of new pharmaceuticals that avoid the serious side effects of current therapies.
June 9, 2025 — Source

Shocking brain cancer breakthrough: Electric fields supercharge immune assault
Electric field device placed on the scalp, along with immunotherapy and chemotherapy may help patients with glioblastoma live longer, particularly those with large, inoperable tumors
June 9, 2025 — Source

Structured exercise strengthens immune response in cancer treatment
Exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumors, according to a first-of-its-kind pilot study from the University of Surrey and Royal Surrey NHS Foundation Trust. Researchers are now looking to invite more patients to take part in a larger clinical trial called OPTIMUS, led by Consultant General Surgeon and scientist Professor Adam Frampton, to understand how these early results could help improve cancer treatment on a wider scale.
June 9, 2025 — Source

Study delves into the complexity of the most aggressive form of prostate cancer
Cancer cannot be understood as a single, uniform disease. The more we delve into studying each type of tumor, the more we recognize the need to subclassify the disease. This concept has led to what we now call precision oncology, characterizing the molecular features of a patient's specific cancer to determine the most effective treatment.
June 9, 2025 — Source

Study: Appendix cancer incidence has quadrupled in older Millennials
In a study estimating the incidence rates of appendiceal adenocarcinoma (AA), or appendix cancer, across birth cohorts in the United States, researchers observed a sharp increase in AA incidence rates for those born after 1945, particularly for Generation X and Millennials. These patterns suggest a timely need for etiologic research and increased AA awareness among physicians and the public.
June 9, 2025 — Source

Terahertz polarimetry detects microscopic tissue changes linked to cancer and burns
Recent advances in electronics and optics have opened new possibilities for terahertz (THz) waves—an invisible type of light that falls between infrared light and microwaves on the spectrum. The use of THz scattering for medical diagnosis is a promising frontier in this field, as THz waves can probe tissue structures in ways that traditional imaging methods cannot. Emerging THz measurement methods have the potential to detect subtle changes in tissue architecture that occur in diseases like cancer and burn injuries, serving as a powerful diagnostic tool.
June 9, 2025 — Source

Unnecessary cancer screenings continue years after guidelines change, study finds
Stopping the widespread use of unnecessary, potentially even harmful, cancer screenings can take up to 13 years and potentially even longer after new guidelines are put in place, according to a new study published in BMJ Quality & Safety.
June 9, 2025 — Source

Why don't bats get cancer? Researchers discover protection from genes and strong immune systems
A study to look at why long-lived bats do not get cancer has broken new ground about the biological defenses that resist the disease.
June 9, 2025 — Source

Health — Cancer — June 6th, 2025

Better brain care score linked to lower risk of heart disease and cancer
A new study from researchers at Mass General Brigham has found that a higher McCance Brain Care Score not only associates with the risk of brain-related conditions such as stroke, dementia, and depression but also strongly associates with developing cardiovascular disease and three common types of cancer.
June 6, 2025 — Source

Magnetically-driven innovative solution developed for personalized intracranial tumor therapy
Brain tumors remain among the most challenging conditions in modern medicine. Due to their complexity and location, many of them are difficult to access, even with the most advanced surgical and therapeutic approaches. Although significant progress has been made in radiotherapy, chemotherapy, and surgical techniques, certain tumors—especially those near critical brain structures—still present considerable risks.
June 6, 2025 — Source

Mailed self-collection HPV tests more than double cervical cancer screening rates, study shows
Mail-in self-collection tests for human papillomavirus (HPV) more than doubled cervical cancer screening participation among never- and under-screened U.S. women, according to a first-of-its-kind study by researchers at the University of Texas MD Anderson Cancer Center.
June 6, 2025 — Source

Mitochondrial DNA variant predicts resistance to melanoma immunotherapy
Results from a new study help resolve the decade-long mystery of why many patients with the deadliest form of skin cancer do not respond to the latest cancer treatments. Specifically, researchers found patients with metastatic melanoma who did not respond to immune checkpoint inhibitors had DNA with differences not found in the DNA of those who did respond. These genetic differences are both testable and predictive of who is least likely to respond to checkpoint therapies, a treatment class that has become a mainstay against the disease.
June 6, 2025 — Source

Novel imaging strategy detects multiple sub-types of triple negative breast cancer
This approach has the potential to lead to better diagnosis, treatment planning, and monitoring for patients with TNBC.
June 6, 2025 — Source

Obesity linked to subsequent neoplasms in childhood cancer survivors
Lenat Joffe, M.D., from Northwell in New Hyde Park, New York, and colleagues examined associations between time-varying BMI/physical activity and subsequent neoplasm risk among childhood cancer survivors in a retrospective cohort analysis. Five-year childhood cancer survivors diagnosed at younger than 21 years of age between 1970 and 1999 were enrolled and followed through September 2019.
June 6, 2025 — Source

Oncologists push for age inclusive use of cancer treatments
Recent advances have resulted in highly effective "tissue-agnostic" drugs that treat cancers based on their molecular markers rather than their tissue of origin, but very few of these drugs are approved for use in children. In an opinion paper publishing June 5 in the Cell Press journal Trends in Cancer, oncologists call for "ag(e)nostic" cancer treatments: drugs that are both tissue agnostic and approved for cancer patients of all ages.
June 6, 2025 — Source

OpenAI's marketing head takes leave to undergo breast cancer treatment
OpenAI's head of marketing, Kate Rouch, has announced she's stepping away from her role for three months while she undergoes treatment for invasive breast cancer.
June 6, 2025 — Source

Study aims to demystify the immune toxicity triggered by osimertinib-ICI co-treatment
Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases and remains a leading cause of cancer mortality worldwide. Epidermal growth factor receptor (EGFR) mutations are common in NSCLC and have made EGFR-targeting drugs like osimertinib a cornerstone of treatment. Immune checkpoint inhibitors have also transformed the treatment landscape by reactivating the immune system to attack tumors. Despite their promise, combining these two therapies has proven problematic. Several clinical trials were halted after reporting high incidences of severe immune-related adverse events (irAEs)—such as interstitial pneumonia and hepatitis—linked to the combination.
June 6, 2025 — Source

Tumor diagnostics: AI model detects more than 170 types of cancer
The MRI shows a brain tumor in an inauspicious location, and a brain biopsy will entail high risks for a patient who had consulted doctors due to double vision. Situations such as this case prompted researchers at Charite—Universitätsmedizin Berlin to look for new diagnostic procedures. The result is an AI model.
June 6, 2025 — Source

Health — Cancer — June 3rd, 2025

Clairity BREAST receives FDA authorization for AI-based breast cancer risk prediction
Clairity, Inc., a digital health innovator advancing AI-driven healthcare solutions, has received U.S. Food and Drug Administration (FDA) De Novo authorization for CLAIRITY BREAST, a novel, image-based prognostic platform designed to predict five-year breast cancer risk from a routine screening mammogram. With this authorization, Clairity is planning to launch among leading health systems through 2025 -- propelling a new era of precision medicine in breast cancer.
June 3, 2025 — Source

Histotripsy stimulates the immune system to attack cancer cells outside the liver
After FDA approval in late 2023, the non-invasive liver tumor treatment histotripsy has been used at University of Michigan Health since early 2024.
June 3, 2025 — Source

Pancreatic cancer spreads to liver or lung thanks to this protein
Scientists have discovered how pancreatic cancer cells thrive in the lungs or liver, environments that are as distinct to cells as the ocean and desert are to animals. The spread of cancer cells to organs like these often produces the very first symptoms of pancreatic cancer. But by that time, the pancreatic cancer has spread out of control.
June 3, 2025 — Source

Rapid Biomimetic Nanovaccine for Personalized Cancer Therapy
A recent article in Nature Communications describes a nanovaccine platform designed to support the development of personalized cancer vaccines. This approach uses tumor cell membranes enriched with neoantigens to improve antigen presentation.
June 3, 2025 — Source

Safeguarding fertility in the battle against gynecologic cancer
For decades, gynecologic cancer treatment has used aggressive surgical intervention and chemotherapy. These methods often harmed fertility. They also caused severe side effects and an uncertain prognosis.
June 3, 2025 — Source

Study identifies proteins involved in the effectiveness of immunotherapy against blood cancer
A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).
June 3, 2025 — Source

Study: Elinzanetant cuts vasomotor symptoms in women with breast cancer on endocrine therapy
For women with moderate-to-severe vasomotor symptoms associated with endocrine therapy for hormone receptor (HR)-positive breast cancer, elinzanetant, a neurokinin-targeted therapy, reduces the frequency of vasomotor symptoms, according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago.
June 3, 2025 — Source

Team uses AI and microbiome analysis to accurately colorectal cancer through gut bacteria
Researchers have been working toward using the gut microbiome as a clinical target for screening for colorectal cancer. This would ideally allow simple stool tests to be used for early detection of the disease in place of expensive procedures such as colonoscopies.
June 3, 2025 — Source

Updated data from Phase I study of antibody-drug conjugate EBC-129 released
The Experimental Drug Development Center (EDDC), Singapore's national platform for drug discovery and development, has announced the presentation of updated clinical data for the ongoing Phase I trial for EBC-129 at the 2025 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.
June 3, 2025 — Source

Health — Cancer — May 30th, 2025

Alcohol-fueled cancer deaths are on the rise in the US
A new study led by experts at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, is the first to look at trends over time in alcohol-linked cancer mortality across the United States.
May 30, 2025 — Source

HER3-targeted antibody-drug conjugate shows promise for treatment-resistant solid tumors
A new targeted cancer drug, DB-1310, is showing early signs of effectiveness in patients with advanced solid tumors that have not responded to standard treatments, particularly those with EGFR-mutant non-small cell lung cancer (NSCLC), according to results from an international clinical trial led by Dr. Aaron Lisberg at the UCLA Health Jonsson Comprehensive Cancer Center.
May 30, 2025 — Source

Innovative immunotherapy shows promise against aggressive T cell cancers
A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international Phase I/II clinical trial led by researchers at Washington University School of Medicine in St. Louis.
May 30, 2025 — Source

Massachusetts brain tumor cluster: Nurses not satisfied with Newton-Wellesley study
A nurses' union isn't satisfied with a Mass General Brigham investigation that found the brain tumor cluster at Newton-Wellesley Hospital is not connected to working conditions.
May 30, 2025 — Source

New standard of care emerges for multiple myeloma
A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical Oncology (ASCO), held May 30 through June 3 in Chicago.
May 30, 2025 — Source

Number of cancer survivors in the US reaches 18.6 million—projected to exceed 22 million by 2035
The number of people living with a history of cancer in the United States is estimated at 18.6 million as of January 1, 2025 and projected to exceed 22 million by 2035, according to a new report, "Cancer Treatment and Survivorship Statistics, 2025," led by the American Cancer Society (ACS). The study also found notable disparities in treatment for many common cancers, including lung and colorectal.
May 30, 2025 — Source

People with disabilities are dying from preventable cancers, study shows
People with disabilities are missing out on screening programs that could help detect cancer early, and after diagnosis, are less likely to survive, our study shows.
May 30, 2025 — Source

Scientists pioneer promising treatment derived from cactus-like plant for intractable cancer pain
National Institutes of Health (NIH) scientists report that a first-in-human clinical trial of a new therapy based on the plant-derived molecule resiniferatoxin (RTX) shows that it is a safe and effective agent for pain control in patients with intractable cancer pain.
May 30, 2025 — Source

Small molecule inhibitors restore normal BRAF structure, offering insight into cancer-causing mutations
Researchers led by Universite de Montreal pathology and cell-biology professor Marc Therrien have identified major structural changes that enable the BRAF protein to escape control and mimic its activation, giving it strong potential to cause cancer.
May 30, 2025 — Source

Therapeutic target could prevent chronic gut inflammation from turning into cancer
Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases such as ulcerative colitis or Crohn's disease usually manifest between the ages of 15 and 29—a critical period for education and early career development. Prompt diagnosis and treatment are crucial.
May 30, 2025 — Source

TRR 417 initiative aims to unlock new treatments for colorectal cancer
In the realm of colorectal cancer treatments beyond surgery and radiation, one key question gained prominence in recent years: Is the tumor's DNA repair system defective, making it "microsatellite unstable"? Around 15 to 20 percent of all tumors have this trait, making them likely candidates for successful immunotherapy. So-called immuno-checkpoint inhibitors are often used in these cases to neutralize the tumor's "protective shield", which tricks the immune system into perceiving it as harmless tissue. Once this deception is lifted, the body's T-cells can eliminate the tumor.
May 30, 2025 — Source

US medical org pays $50M+ to settle case after crims raided data and threatened to swat cancer patients
Cash splashed on damages, infrastructure improvements, and fraud monitoring
May 30, 2025 — Source

Health — Cancer — May 28th, 2025

AI helps ID candidates for targeted breast cancer treatment
Thanks to artificial intelligence (AI), more women might soon benefit from targeted breast cancer treatment, a new study says.
May 28, 2025 — Source

ASCO: GLP-1 receptor agonists may reduce risk for obesity-related cancer, all-cause death
For adults with diabetes and obesity, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are associated with a reduced risk for obesity-related cancer compared with dipeptidyl peptidase-4 (DPP-4) inhibitors, according to a study scheduled to be presented at the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago.
May 28, 2025 — Source

Children and young people are waiting longer than necessary for cancer diagnosis, according to new research
A study, led by experts at the University of Nottingham, has found that young people suffering from certain types of cancer, such as bone tumors, are experiencing lengthy times to diagnosis. The Childhood Cancer Diagnosis Study is published in The Lancet Regional Health—Europe.
May 28, 2025 — Source

New scoring system improves colorectal cancer risk prediction
A newly developed scoring system could enhance risk prediction and guide treatment decisions for colorectal cancer, according to a study published in the Journal of Clinical Oncology.
May 28, 2025 — Source

What is Mohs micrographic surgery? 8 FAQs about Mohs
One in five Americans is likely to get skin cancer in their lifetime, making it the most common type of cancer in the U.S. But the good news is that it's highly treatable when caught early, especially if it can be treated with Mohs micrographic surgery.
May 28, 2025 — Source

Wildfire pollution may lower survival of lung cancer patients
Breathing in wildfire pollution may make it harder for people with lung cancer to survive, according to a new study from UC Davis Comprehensive Cancer Center researchers.
May 28, 2025 — Source

Women with low muscle mass may have a worse prognosis in breast cancer treatment
Maintaining muscle mass has proven to be crucial for patients undergoing cancer treatment. Studies have shown that individuals with more muscle tend to respond better to therapies such as chemotherapy and radiotherapy. They also have a lower risk of complications and experience more effective recovery.
May 28, 2025 — Source

Health — Cancer — May 27th, 2025

Copper death-inhibiting compounds isolated from eucalyptus fruits show promise for cancer therapy
Researchers have isolated two novel bis-&beta-triketone hybrids, Corymbinols A (1) and B (2a/2b), from the fruits of Corymbia citriodora. Corymbinol A demonstrated a 31% inhibition of cuproptosis in HepG2 cells at a concentration of 20 μM, suggesting its potential as a non-toxic therapeutic option against liver cancer.
May 27, 2025 — Source

Mapping tumor microenvironments to predict lung cancer immunotherapy response
Amidst the continued struggle to treat non-small-cell lung cancer, a new study led by Stanford University scientists suggests that a patient's response to immunotherapy may hinge on how immune cells cluster around tumors. Their results reveal that spatial arrangements of certain immune cells within tumors can serve as powerful predictors of treatment response, surpassing existing biomarker tests.
May 27, 2025 — Source

Health — Cancer — May 23rd, 2025

Alcohol-related cancer deaths in the US nearly double over 30 years
Alcohol-fueled cancer deaths nearly doubled in the United States during the past three decades, with cases among men driving this surge, a new study says.
May 23, 2025 — Source

Colon Cancer Explained: What You Can Do to Identify and Prevent It
Here's why some habits, such as increased exercise, can decrease your risk of colon cancer.
May 23, 2025 — Source

Enzalutamide helps extend life for men with advanced prostate cancer, five-year follow-up finds
The combination of enzalutamide with androgen deprivation therapy (ADT) significantly increases the chance of five-year survival for men with metastatic hormone-sensitive prostate cancer, according to a five-year follow-up of the global ARCHES study led by the Duke Cancer Institute.
May 23, 2025 — Source

Korea's National Cancer Center to deploy robotic bronchoscopy and more briefs
Also, Gleneagles Hospital Chennai in India is embarking on brain health research to develop AI-powered solutions.
May 23, 2025 — Source

Nanoscale biosensor lets scientists monitor molecules in real time
Drawing inspiration from our gut protection mechanisms, researchers have engineered a new type of sensor to monitor substances over long stretches - measuring reactions for up to a week after being implanted in living rats.
May 23, 2025 — Source

Novel long noncoding RNA may serve as therapeutic target for prostate cancer
Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 nucleotides longer than typical RNAs and are widely expressed in cells, could serve as a prognostic biomarker and therapeutic target for prostate cancer, according to a recent study published in Science Advances.
May 23, 2025 — Source

Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes
Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at Baylor College of Medicine and the University of Texas MD Anderson Cancer Center use RNA sequencing to characterize bone metastases from eight cancer types. The findings identify three distinct immune ecosystem archetypes.
May 23, 2025 — Source

Skin cancer is a growing threat to older adult men as global population ages
Researchers at the First Affiliated Hospital of Chongqing Medical University in China have uncovered a sharply rising burden of skin cancer in older adults driven largely by population growth and affecting men twice as often.
May 23, 2025 — Source

Study uncovers source of genetic variation influencing childhood brain tumors
Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the disease begins, develops and potentially how to control it or eliminate it.
May 23, 2025 — Source

Health — Cancer — May 22nd, 2025

A machine learning tool can help with diagnosing, monitoring colorectal cancer
Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.
May 22, 2025 — Source

Additional imaging techniques can detect early stage cancers missed by mammograms in women with dense breasts
In women with dense breasts (breasts with relatively low levels of fatty tissue) and a negative mammogram, supplemental imaging techniques detect early-stage cancers, with imaging techniques three times more effective than ultrasound, finds a Phase III randomized control trial published in The Lancet.
May 22, 2025 — Source

At Griffin Health, AI helps point out patients that clinicians should screen for cancer
'These are real lives, potentially extended or saved because an AI system surfaced the right data at the right time, and our teams were equipped to act on it,' says the health system's COO. And the tech has helped boost the case closure rate by 50%.
May 22, 2025 — Source

Childhood cancer survivors have increased risk for chronic kidney disease and hypertension: Study
Childhood cancer survivors (CCS) have an increased risk of chronic kidney disease (CKD) and hypertension, according to a study published online May 19 in JAMA Network Open.
May 22, 2025 — Source

Discovering new ways to recharge T-cells fighting cancer
A pair of recent studies from the laboratory of Bin Zhang, MD, Ph.D., the Johanna Dobe Professor of Cancer Immunology, have uncovered new details about critical biological processes that may help improve cancer treatments.
May 22, 2025 — Source

DNA patterns provide key insights in the diagnosis of childhood leukemia
The treatment of leukemia among children could be made more precise with fewer side effects with the help of more accurate methods of diagnosis. A new study led by Umeå University, Sweden, reveals that analyzing methylation patterns in the child's leukemic cells DNA can enhance risk assessment, helping to ensure that only the children who need the most intensive treatment receive it.
May 22, 2025 — Source

Gene delivery system uses nanostraws and electrical pulses to engineer cancer-fighting immune cells
Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells. The platform, called Nanostraw Electro-actuated Transfection (NExT), uses tiny hollow nanostructures and electrical pulses to insert a wide variety of biomolecules—proteins, mRNA and gene-editing tools—into immune cells with high efficiency and minimal disruption.
May 22, 2025 — Source

Gut bacteria and diet found to affect cancer treatment outcomes
A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.
May 22, 2025 — Source

In vitro cancer model reveals how tumor cells access the bloodstream
Tumors are made up of millions of cells, and removing all of these cells surgically or eliminating them with medication becomes much more difficult after the cancer has spread to other parts of the body.
May 22, 2025 — Source

'It's rare and it's scary.' Dark spot on your fingernail could mean cancer
If you are staring at a dark spot under your fingernail, you may want to see a dermatologist. It could be a form of melanoma.
May 22, 2025 — Source

Key mechanism in embryonic development makes colorectal cancer more aggressive, study finds
Tumor cells in colorectal cancer exploit an important signaling pathway that normally controls embryo development. Researchers have now shown how a protein that controls the development of the arms and heart contributes to making colorectal cancer cells more aggressive and likely to spread.
May 22, 2025 — Source

Meta analysis highlights prognostic role of circPVT1 in solid tumors
circPVT1 has emerged as a key regulator in disease progression and clinical outcomes. However, its prognostic relevance and association with clinicopathological parameters in solid malignancies remain to be fully elucidated. To address this, we conducted a meta-analysis to elucidate the clinical significance of circPVT1 in solid tumors.
May 22, 2025 — Source

More evidence links physical activity with improved cancer survival
A new large analysis led by American Cancer Society (ACS) researchers shows engaging in leisure-time moderate-to-vigorous physical activity (MVPA) after a cancer diagnosis improves survival for people with several cancer types, including bladder, breast, colon, endometrial, kidney, lung, oral, prostate, rectal, and respiratory cancer.
May 22, 2025 — Source

New AI blood test tracks pancreatic cancer treatment response
An artificial intelligence technique for detecting DNA fragments shed by tumors and circulating in a patient's blood, developed by Johns Hopkins Kimmel Cancer Center investigators, could help clinicians more quickly identify and determine if pancreatic cancer therapies are working.
May 22, 2025 — Source

New approach to evaluating cases with rheumatic reactions to cancer immunotherapy
The prevalence and severity of rheumatic adverse reactions in cancer immunotherapy is significantly underestimated, due to the lack of standardized screening protocols for malignancies in patients with autoimmune disorders. In response to the need for data collection and diagnostic criteria, researchers have developed a trans-disciplinary approach to safeguard those patients at risk.
May 22, 2025 — Source

New combination therapy found safe and feasible for neuroendocrine tumor patients
A new combination therapy that pairs a radiopharmaceutical with a DNA-repair blocker has been deemed feasible and tolerable for neuroendocrine cancer patients. The combined therapy works by preventing cancer cells from repairing themselves after targeted treatment and has the potential to help patients achieve longer-lasting disease control.
May 22, 2025 — Source

Study sheds light on how tumor clusters enter the bloodstream
Tumors are made up of millions of cells, and removing all of these cells surgically or eliminating them with medication becomes much more difficult after the cancer has spread to other parts of the body.
May 22, 2025 — Source

Supplemental imaging techniques improve cancer detection in women with dense breasts
In women with dense breasts (breasts with relatively low levels of fatty tissue) and a negative mammogram, supplemental imaging techniques detect early-stage cancers, with imaging techniques three times more effective than ultrasound, finds a phase 3 randomized control trial published in The Lancet.
May 22, 2025 — Source

Wastewater helps monitor cancer-causing HPV
Scientists in Uruguay have found genotypes of the human papillomavirus (HPV) linked to cervical cancer in urban wastewater, saying it could help inform disease prevention efforts.
May 22, 2025 — Source

What does it mean for Biden's prostate cancer to be 'aggressive'? A urologic surgeon explains
Former President Joe Biden has been diagnosed with an "aggressive" form of prostate cancer that has spread to his bones. But what does it mean for this type of cancer to be called aggressive?
May 22, 2025 — Source

Health — Cancer — May 13th, 2025

AI tool enhances detection of tiny breast cancer signs in mammograms
Each year, millions of women undergo mammography to screen for breast cancer, yet tiny calcium specks—known as microcalcifications—often evade detection or are misread, leading to delayed diagnoses or unnecessary biopsies. Conventional computer-aided tools rely on hand-crafted rules and struggle with the sheer variety of imaging devices and lesion patterns.
May 13, 2025 — Source

Bioprinted organoids capture tumor features and predict prognosis based on shape
A joint research team affiliated with UNIST has developed a 3D-printed artificial tumor tissue capable of replicating the in vivo conditions of patient-derived cancer cells. This innovative model not only simulates the tumor microenvironment but also integrates artificial intelligence (AI) technology that can predict patient prognosis solely from images of tumor growth.
May 13, 2025 — Source

Biosensor uses pH-responsive DNA nanoswitches for highly sensitive bladder cancer detection in urine
A study published in ACS Nano presents a novel biosensor for the isothermal, highly sensitive detection of bladder cancer biomarkers—miRNAs, short non-coding RNAs that regulate gene expression—using programmable pH-responsive triplex DNA nanostructures.
May 13, 2025 — Source

Breast tissue changes could predict aggressive cancer and poor survival rates
Researchers at the National Institutes of Health (NIH) have identified a series of changes in the architecture and cell composition of connective tissues of the breast, known as stromal tissue, that is associated with an increased risk of developing aggressive breast cancer among women with benign breast disease, and poorer rates of survival among women with invasive breast cancer.
May 13, 2025 — Source

'Cell line atlas' provides a crucial resource for developing therapies for biliary tract cancer
Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a rare and aggressive group of cancers, carrying one of the worst prognoses in all of oncology. Only about 10% of patients survive beyond five years.
May 13, 2025 — Source

Computational framework reveals how cancers rewire driver genes to beat chemotherapy
Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer. Chemotherapy then adds a new evolutionary pressure, encouraging further genetic changes that let tumors bounce back.
May 13, 2025 — Source

Fragmented care does not affect survival outcomes for retroperitoneal sarcoma, says research
Fragmented care—receiving medical treatment at more than one facility—has been associated with both positive and negative outcomes for cancer patients depending on a number of factors such as cancer type and treatment venue.
May 13, 2025 — Source

New approach to treating aggressive breast cancers shows significant improvement in survival
A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to researchers. In a trial where cancers were treated with chemotherapy followed by a targeted cancer drug before surgery, 100% of patients survived the critical three-year period post-surgery.
May 13, 2025 — Source

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers
A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to Cambridge researchers.
May 13, 2025 — Source

NIH researchers discover tissue biomarker that may indicate higher risk of aggressive breast cancer development and death
Researchers at the National Institutes of Health (NIH) have identified a series of changes in the architecture and cell composition of connective tissues of the breast, known as stromal tissue, that is associated with an increased risk of developing aggressive breast cancer among women with benign breast disease, and poorer rates of survival among women with invasive breast cancer.
May 13, 2025 — Source

Protein DNM1 identified as key regulator in ovarian cancer metastasis
Ovarian cancer remains the leading cause of death among cancers affecting the female reproductive system, largely because current treatments are not effective once the cancer has spread (metastasized) beyond the ovaries.
May 13, 2025 — Source

Radiomics reveals breast texture patterns associated with cancer risk
In one of the larger studies of its kind, researchers have identified six breast texture patterns that may be associated with increased cancer risk, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).
May 13, 2025 — Source

Six breast texture patterns linked to higher risk of invasive cancer
In one of the larger studies of its kind, researchers have identified six breast texture patterns that may be associated with increased cancer risk, according to a study published in Radiology.
May 13, 2025 — Source

Trump slashed US cancer research by 31 percent: Senate report
US President Donald Trump's administration cut cancer research funding by 31% in the first three months of 2025 compared to the same period last year, according to a Senate report released Tuesday that accuses the White House of waging a "war on science."
May 13, 2025 — Source

Health — Cancer — May 9th, 2025

Aboriginal and Torres Strait Islander women and breast cancer
Researchers have sought to improve our understanding of why Aboriginal and Torres Strait Islander women (respectfully referred to hereon as Aboriginal) with breast cancer can have poorer outcomes than non-Aboriginal women.
May 9, 2025 — Source

Fat-rich fluid found to fuel immune failure in ovarian cancer
New research led by Irish scientists has uncovered how lipid-rich fluid in the abdomen, known as ascites, plays a central role in weakening the body's immune response in advanced ovarian cancer. The findings offer new insights into immune suppression in ovarian cancer and open promising avenues for future immunotherapy approaches.
May 9, 2025 — Source

How a protein and immune patterns in melanoma offer clues to more personalized treatments
Melanoma is one of the most aggressive forms of skin cancer, arising from pigment-producing cells called melanocytes. While early-stage melanoma can often be treated successfully, advanced disease remains difficult to manage. One of the reasons is that responses to modern immunotherapy vary widely—some tumors shrink dramatically, while others do not respond at all.
May 9, 2025 — Source

Mammograms after age 75: Study suggests regular screening may save lives
For women aged 40 to 74, a mammogram every year or every other year is the standard recommendation in screening for breast cancer. Regular mammograms reduce the risk of late-stage breast cancer and improve breast cancer survival rates. But the guidance has been less clear for women aged 75 and older.
May 9, 2025 — Source

New treatment combination for rectal cancer patients offers improved rates of complete remission
A new trial of patients with advanced rectal cancer has found that the addition of immunotherapy treatment alongside extended radiotherapy led to better rates of remission.
May 9, 2025 — Source

Probiotic supplementation may help reduce chemotherapy side effects in breast cancer
Chemotherapy is one of the most popular ways to treat breast cancer. Even though it has proven to be effective, it also has downsides, such as a higher risk of side effects, as it doesn't only attack the cancer cells but can also affect normal cells. Chemotherapy-related side effects such as fatigue, weakness, and proneness to infections can influence treatment adherence and undermine the effectiveness of the therapy and the patients' quality of life.
May 9, 2025 — Source

Serena-backed health tech lands first FDA approval for home cervical cancer test
For the first time, the FDA has just approved a device that lets people screen for cervical cancer from home.
May 9, 2025 — Source

Studies point to redlining as a 'perfect storm' for breast cancer
In neighborhoods across America, women face a daunting threat from a federal practice that, although it was outlawed decades ago, continues to negatively impact their health today.
May 9, 2025 — Source or Source

The translational power of liquid biopsy could improve clinical gynecologic oncology
A review now published in the Journal of Experimental & Clinical Cancer Research offers a sweeping and authoritative synthesis of the use of liquid biopsy in gynecological oncology, placing this emerging tool at the forefront of precision medicine for women.
May 9, 2025 — Source

Understudied mental health challenges among caregivers of cancer patients: A call for targeted support
A study published in Scientific Reports reveals a significant prevalence of mental health concerns among Vietnamese family caregivers of lung cancer patients, highlighting the urgent need for targeted support.
May 9, 2025 — Source

Health — Cancer — May 6th, 2025

AI tool automates liver tumor detection and monitoring
Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Radiomics Group, led by Raquel Perez-Lopez, have developed SALSA (System for Automatic Liver tumor Segmentation And detection), a fully automated deep learning-driven tool for the precise and completely automated detection and monitoring of liver tumors (hepatocellular carcinoma).
May 6, 2025 — Source

Diabetes drug shows potential to slow prostate cancer cell growth
An international team of scientists led by the Medical University of Vienna has identified similarities in the mechanisms of diabetes and cancer: as the researchers show, the protein PPARγ, which is central to the regulation of metabolic processes, can also influence the growth of prostate cancer cells. PPARγ is already known to be a target of certain drugs used to treat type 2 diabetes.
May 6, 2025 — Source or Source

Low-coordination Mn single-atom nanozymes enable imaging-guided cancer therapy
A research team led by Prof. Wang Hui from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS), in collaboration with researchers led by Prof. Qian Junchao from HFIPS and Prof. Qu Songnan from the University of Macau, has successfully developed a novel low-coordination single-atom manganese nanozyme using a unique "molecular carbonization-reduction" strategy.
May 6, 2025 — Source

New analysis helps discern benign from malignant thyroid growths
Telling the difference between benign and cancerous thyroid nodules before surgery is notoriously challenging, but a new study finds that a combination of artificial intelligence and data analysis techniques may yield surprisingly accurate cancer predictions.
May 6, 2025 — Source

Often seen as waste, stool may yield clues to microbiome's role in cancer treatment
At Mayo Clinic's Center for Individualized Medicine, scientists are investigating stool samples to uncover new insights into cancer treatment. Often seen as waste, stool may provide valuable information about the microbiome—a complex ecosystem of microorganisms, including bacteria, fungi and viruses in the gut.
May 6, 2025 — Source

Phase separation by fusion protein FC reveals new mechanism for tumor development in rare cancer
Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered regions (IDRs) can drive membrane curvature formation in artificial vesicles through liquid-liquid phase separation (LLPS); however, direct evidence for LLPS-mediated endomembrane remodeling in living cells has been lacking.
May 6, 2025 — Source

Second opinions don't significantly delay breast cancer treatment
But women shouldn't let worries about delaying treatment deter them from seeking a second opinion on their diagnosis and treatment, researchers say.
May 6, 2025 — Source

Tiny cellular 'antennae' could be fueling cancer, scientists warn
Microscopic command centers in our bodies called primary cilia—once thought irrelevant—could be hidden switches powering cancer growth and drug resistance, new research reveals.
May 6, 2025 — Source

Trump's Latest NIH Purge Kills the National Cancer Hotline
Roughly 200 more employees at the National Institutes of Health will be laid off, reportedly to balance out recent rehires.
May 6, 2025 — Source

When a gene quality-control mechanism fails, abnormal RNA strands may contribute to cancer and neurodegeneration
Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that increase cell stress and may contribute to diseases such as cancer and neurodegeneration, a new study has found.
May 6, 2025 — Source

Health — Cancer — May 5th, 2025

ATM mutations alone do not predict early treatment need in chronic lymphocytic leukemia, study finds
In chronic lymphocytic leukemia (CLL), certain recurrent genetic alterations are known to influence disease progression and survival. One important abnormality is the loss of part of chromosome 11, del(11q), which is associated with a more aggressive disease course. However, it has remained unclear whether mutations in the ATM gene, which is also located in this region, have a similar impact.
May 5, 2025 — CMAJ (Canadian Medical Association Journal) found an increase in asthma-related emergency department (ED) visits across Ontario following heavy smoke in early June 2023." target="new" class="RM1">Source

Can vitamin D prevent colorectal cancer? The science is promising—but not straightforward
The potential role of vitamin D in preventing and treating colorectal cancer (CRC) has attracted growing research interest—especially as CRC rates are rising, particularly among younger adults. This isn't a new area of study. Low vitamin D levels have long been linked to a higher risk of developing colorectal cancer.
May 5, 2025 — Source

Liver cancer survival rates reflect income disparities
The risk of dying from the most common form of primary liver cancer is about 30% higher for patients with low household income compared to those with middle or high household income, according to a study from the University of Gothenburg.
May 5, 2025 — Source

Rare spinal tumor removed through patient's eye socket
In a first-of-its-kind surgery, a team led by a University of Maryland Medical Center (UMMC) neurosurgeon has successfully removed a rare cancerous tumor wrapped around the spine and spinal cord of a 19-year-old woman—through her eye socket (orbit).
May 5, 2025 — Source

Structural barriers may prevent cancer care for people living with HIV
People living with HIV are less likely to receive potentially lifesaving cancer treatment if they live in communities with lower income levels and educational attainment, according to a new national study led by researchers from Moffitt Cancer Center.
May 5, 2025 — Source

Suppressing key enzymes could improve lung cancer treatment outcomes
Blocking proteins that cause cancer cells to mutate and resist treatment could significantly improve outcomes for some patients with non-small cell lung cancer (NSCLC), the most common type of lung cancer, according to a new Yale study.
May 5, 2025 — Source

Under the hood: Probing the molecular mechanisms of metastasis
Cells have a mailing system of sorts. They can release tiny molecular balls, called extracellular vesicles (EVs), that contain biological matter or messages and attach to other cells to share whatever they contain.
May 5, 2025 — Source

Understanding genetic factors behind a pediatric brain tumor and possible treatments
Pediatric pilocytic astrocytoma (PA) is a common type of low-grade brain tumor in children, influenced by specific genetic changes. Researchers at Washington University School of Medicine in St. Louis have conducted a study using advanced stem cell techniques to investigate the genetic alterations that cause PA and how they affect tumor growth. Their findings shed light on molecular pathways that could lead to new targeted therapies, offering hope for better treatment options for children with PA.
May 5, 2025 — Source

Health — Cancer — May 2nd, 2025

Gene-editing therapy shows early success in fighting advanced gastrointestinal cancers
Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results, recently published in The Lancet Oncology, show encouraging signs of the safety and potential effectiveness of the treatment.
May 2, 2025 — Source

Lysosomal lipid peroxidation drives ferroptosis in cancer cells
The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell death, is also necessary for the proper development and function of the body. It has also been a focus of researchers developing treatments for cancer by finding ways to activate the cell death of cancer cells themselves.
May 2, 2025 — Source

Self-assembling nanospheres offer a new method for RNA delivery in cancer treatment
Researchers describe a concentric supraparticle system that protects and delivers RNA therapeutics for gene silencing in cancer models.
May 2, 2025 — Source

Sun safety declining in Canada amid rise in skin cancer cases
Despite decades of public health messaging, Canadians are spending more time in the sun and using less sun protection—raising alarms among researchers as melanoma cases continue to climb.
May 2, 2025 — Source

Health — Cancer — April 28th, 2025

Antibody-based drug dismantles a metabolic barrier to anti-tumor immunity
A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses. Harnessing that insight, researchers led by Ludwig Lausanne's Ping-Chih Ho and Yi-Ru Yu—along with Sheue-Fen Tzeng and Chin-Hsien Tsai, former post-docs in the Ho lab who now lead their own labs at Taipei Medical University in Taiwan—have developed a humanized antibody to dismantle that barrier as a potential cancer immunotherapy.
April 28, 2025 — Source

Covalent Werner helicase inhibitor shows clinical proof-of-concept in Phase I trial
For patients with cancers harboring certain genetic defects, the first-in-class targeted therapy RO7589831, which targets the DNA repair enzyme Werner helicase, demonstrated early signals of efficacy and was generally well-tolerated, according to Phase I trial data reported by researchers at The University of Texas MD Anderson Cancer Center.
April 28, 2025 — Source

HER2 targeted therapy shows promise in previously treated lung cancers
The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer—particularly those with specific HER2 mutations—with manageable side effects, according to results from the Phase Ia/Ib Beamion LUNG-1 trial led by researchers from The University of Texas MD Anderson Cancer Center.
April 28, 2025 — Source

High cannabis use linked to increased mortality in colon cancer patients
Researchers at the University of California San Diego School of Medicine have found that individuals with colon cancer and a documented history of high cannabis use were more than 20 times more likely to die within five years of diagnosis compared to those without such a history.
April 28, 2025 — Source

Human protein HSF2 helps wake up sleeping cancer-linked viruses, study finds
A newly established team of researchers at Åbo Akademi University, led by Academy Research Fellow Silvia Gramolelli (Faculty of Science and Engineering), has discovered an additional function for Heat Shock Factor 2 (HSF2), a human transcription factor not previously associated with viral processes.
April 28, 2025 — Source

Long-term study links chronic conditions in midlife to higher cancer risk and mortality
Researchers from Memorial Sloan Kettering Cancer Center and the University of California, Los Angeles, identified that comorbidities in midlife are associated with an increased risk of developing cancer and cancer-related mortality, with associations varying by cancer type. Chronic conditions were linked to higher cancer risks, offering insights that may inform prevention efforts.
April 28, 2025 — Source

Natural killer cells remember and effectively target ovarian cancer, researchers discover
Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumors and effectively attack them. The discovery, published in Cancer Immunology Research, could pave the way for new, more powerful immunotherapies for difficult-to-treat cancers. The paper is titled "Adaptive NK Cells Exhibit Tumour-Specific Immune Memory and Cytotoxicity in Ovarian Cancer."
April 28, 2025 — Source

New topical gel reduces painful rash from colorectal cancer treatment
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center have demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, a common and painful side effect experienced by patients undergoing anti-EGFR therapies for colorectal cancer. The findings of the clinical trial confirm the treatment's safety and effectiveness.
April 28, 2025 — Source

Olaparib and pembrolizumab combination shows early promise in molecularly selected, tumor-agnostic trial
The combination of the PARP inhibitor olaparib and the PD-1 inhibitor pembrolizumab showed initial antitumor activity with no new safety signals in a molecularly matched, tumor-agnostic trial, particularly in patients with BRCA1/2 mutations, according to results from a Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center.
April 28, 2025 — Source

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial
The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer -- particularly those with specific HER2 mutations -- with manageable side effects, according to results from the Phase Ia/Ib Beamion LUNG-1 trial led by researchers from The University of Texas MD Anderson Cancer Center.
April 28, 2025 — Source

Topical gel relieves painful skin rash side effect caused by targeted therapy for colorectal cancer
A new topical gel called LUT014 successfully reduced the severity of a painful acne‐like rash that commonly occurs as a side effect of targeted therapy with epidermal growth factor receptor (EGFR) inhibitors for colorectal cancer, according to a clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.
April 28, 2025 — Source or Source

Urine test could reveal prostate cancer
A study involving researchers from Karolinska Institutet indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample. With the aid of AI and extensive analyses of gene activity in tumors, they have identified new biomarkers of high diagnostic precision.
April 28, 2025 — Source

Health — Cancer — April 25th, 2025

20-year screening program drives down colorectal cancer cases and deaths
A 20-year initiative that offered flexible options for colorectal cancer screening at a major integrated health system doubled colorectal cancer screening rates, cut cancer incidence by a third, halved deaths, and brought racial differences in outcomes to nearly zero, according to a study presented at SourcDigestive Disease Week (DDW) 2025.
April 25, 2025 — Source

Epigenetic signature helps predict risk of metastatic thyroid cancer progression
Researchers from the Endocrine Tumors group at the Germans Trias i Pujol Research Institute (IGTP), in collaboration with five university hospitals, have conducted the first comprehensive study of DNA methylation patterns in metastatic differentiated thyroid cancer (DTC).
April 25, 2025 — Source

Four-gene combo might predict lethality of stomach cancer
Four specific genes serve as a telltale clue to how potentially deadly stomach cancers will develop and progress, a new study says.
April 25, 2025 — Source or Source

IL-17A identified as a potential driver of cancer in familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer. At present, the only treatment available is close endoscopic monitoring with removal of the precursors, known as polyps, although this is also associated with an increased risk.
April 25, 2025 — Source

Malaria infection linked to childhood cancer risk
New data published in The Journal of Immunology uncovered the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea. BL has been associated with P. falciparum malaria since 1958, but the underlying mechanism of how this led to cancer remained a mystery.
April 25, 2025 — Source

Novel cell therapy shows promising results in advanced tumor diseases
In recent years, cell therapies have developed alongside chemotherapy and immunotherapy to become a new pillar in the treatment of patients with blood and lymph gland cancer. In solid tumors, such as skin, lung, or bone and soft tissue cancer (sarcomas), they have not yet proven themselves as a treatment method.
April 25, 2025 — Source

Radioiodine therapy found to improve relative survival rates of differentiated thyroid cancer patients
Differentiated thyroid cancer patients who receive radioiodine (RAI) treatment after surgery have increased relative survival rates compared to those who do not receive the treatment. According to new research published in the April issue of The Journal of Nuclear Medicine, the clear trend for a higher long-term survival rate is observed in subgroups of patients with low- and intermediate-risk disease, while there is special benefit in high-risk diseases. These findings confirm the benefit of RAI therapy for thyroid cancer patients and provide useful information for physicians to consider when determining optimal treatment.
April 25, 2025 — Source

Scientists May Have Figured Out Why Young People Are Getting Colorectal Cancer More Often
New research has found a link between a toxin produced by certain E. coli bacteria and early onset colorectal cancer.
April 25, 2025 — Source

Study identifies how malaria can lead to childhood cancer
New data published in The Journal of Immunology has revealed the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea. BL has been associated with P. falciparum malaria since 1958, but the underlying mechanism of how it led to cancer had remained a mystery.
April 25, 2025 — Source

Surge in immune cells may explain duodenal cancer risk in inherited disease
Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to carrying a high risk of bowel cancer, also greatly increases the risk of duodenal cancer. At present, the only treatment available is close endoscopic monitoring with removal of the precursors, known as polyps, although this is also associated with an increased risk.
April 25, 2025 — Source

Timing of RSV immunization matters for infant protection
The seasonal timing of when infants receive the new respiratory syncytial virus (RSV) immunization is crucial for ensuring its effectiveness, according to Yale research published in JAMA Network Open.
April 25, 2025 — Source

Health — Cancer — April 22nd, 2025

Annual whole-body, low-dose CT aids management of smoldering multiple myeloma
Annual whole-body, low-dose computed tomography (WBLDCT) can improve the management of smoldering multiple myeloma (SMM), according to a study published online March 25 in the Journal of Clinical Medicine.
April 22, 2025 — Source

Blocking APOC1 protein can slow lymphoma cell growth
Diffuse large B-cell lymphoma (DLBCL) is the most common and fast-growing type of non-Hodgkin lymphoma, a cancer that affects the lymphatic system. It makes up around 30--40% of adult non-Hodgkin lymphoma cases worldwide. DLBCL can appear in lymph nodes or other parts of the body and often progresses quickly.
April 22, 2025 — Source

Breast cancer drug Supinoxin shows potential for small-cell lung cancer in new tests
Purdue University scientists have identified the Supinoxin small-molecule drug as a possible new therapy for small-cell lung cancer (SCLC).
April 22, 2025 — Source

Cancer death rates higher for children in neighborhoods with persistent poverty, study finds
The risk for cancer death is higher among children diagnosed in neighborhoods marked by persistent poverty, according to a study published online April 21 in Pediatrics.
April 22, 2025 — Source

DNA origami offers more accurate imaging in the fight against pancreatic cancer
One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami structures to selectively deliver fluorescent imaging agents to pancreatic cancer cells without affecting normal cells.
April 22, 2025 — Source

DNA repair mechanism may hold key to overcoming tumor resistance to radiotherapy
A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for improving cancer treatment outcomes.
April 22, 2025 — Source

Medical marijuana can help cancer patients, finds a large meta-analysis
The use of medical cannabis or marijuana for managing cancer-related symptoms such as pain, appetite loss and nausea has long been contested. The path to reaching a scientific consensus was obstructed by research restrictions posed by the classification of cannabis as a Schedule I controlled substance.
April 22, 2025 — Source

Smart nanotherapy enhances immune attack on melanoma
Researchers have developed an innovative nano-immune agonist that significantly improves immunotherapy outcomes for melanoma—a highly aggressive and hard-to-treat form of skin cancer.
April 22, 2025 — Source

Health — Cancer — April 20th, 2025

Cancer-Causing Arsenic Is Building Up in the World's Rice
Rice feeds more than half of the world's population. Climate change is loading the beloved grain with arsenic, creating a "scary" health burden.
April 20, 2025 — Source

Differentiating cancerous and healthy cells through motion analysis
Researchers from Tokyo Metropolitan University have found that the motion of unlabeled cells can be used to tell whether they are cancerous or healthy. They observed malignant fibrosarcoma cells and healthy fibroblasts on a dish and found that tracking and analysis of their paths can be used to differentiate them with up to 94% accuracy. Beyond diagnosis, their technique may also shed light on cell motility related functions, like tissue healing.
April 20, 2025 — Source

Molecular drivers and emerging treatments in anaplastic thyroid cancer
Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge. A recent review published in Genes & Diseases offers a comprehensive overview of the molecular mechanisms, diagnostic approaches, and therapeutic strategies driving current and future management of this lethal disease. ATC, accounting for a small percentage of thyroid cancers, progresses rapidly and resists conventional therapies, underscoring the urgency for innovative treatment paradigms.
April 20, 2025 — Source

Unmasking Nrf2 as a key driver of treatment resistance in osteosarcoma
A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is reshaping strategies for overcoming treatment resistance.
April 20, 2025 — Source

Health — Cancer — April 17th, 2025

Expanded screening for Lynch Syndrome could cut deaths from colon cancer
Most people have never heard of Lynch Syndrome, but approximately one million Americans have inherited genes that cause the condition, which significantly raises the risk of developing several types of cancers, including colon cancer. Frequent screening can detect many of these cancers early, when they're easier to treat, yet only one in two people with Lynch Syndrome know they have the condition.
April 17, 2025 — Source

Experimental cancer drug could streamline standard tuberculosis treatment and prevent post-TB lung disease
An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping infected cells die a gentler death, Johns Hopkins Medicine investigators report, based on mouse-model research of the lung-damaging disease.
April 17, 2025 — Source

How to prime tumors to be defeated by cancer immunotherapy
One of the best ways to defeat cancer is by rousing the immune system to attack it.
April 17, 2025 — Source

Low-intensity electrical pulses could help the immune system fight cancer
High-intensity electrical pulses have been medically used to destroy tumors while sparing healthy tissue. But lower-intensity pulses may have a different effect—they reshape the battlefield, making tumors more vulnerable to the body's own defenses.
April 17, 2025 — Source

New discovery enhances cell entry for complex cancer drugs
A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.
April 17, 2025 — Source

Scientists hack cell entry to supercharge cancer drugs
A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body. Scientists at Duke University School of Medicine, University of Texas Health Science Center at San Antonio, and University of Arkansas have found a way to improve the uptake of a promising class of cancer-fighting drugs called PROTACs, which have struggled to enter cells due to their large size.
April 17, 2025 — Source

Survey reveals low awareness of innovative cancer treatment among Americans
Roswell Park Comprehensive Cancer Center is at the forefront of a new approach to cancer treatment, called CAR T-cell therapy. The little known, but highly promising technology breakthrough makes it possible for your body to fight cancer, often without invasive surgery, offering patients new hope for the possibility of long-term remission.
April 17, 2025 — Source

Health — Cancer — April 7th, 2025

Breakthrough provides potential for precise melanoma treatment
More than 7,000 melanomas are diagnosed each year in Aotearoa New Zealand, and nearly 300 people annually lose their lives to the disease.
April 7, 2025 — Source

Drug combo offers hope for advanced bladder cancer patients
Urothelium is the term for the mucous membrane that lines the urinary tract. This includes the renal pelvis, ureter, urinary bladder and the upper part of the urethra. In the vast majority of cases, urothelial carcinomas grow in the bladder (bladder carcinoma).
April 7, 2025 — Source

Incidence of RT-induced otitis media with effusion examined in head and neck cancer
For patients with head and neck cancer (HNC), the incidence of radiotherapy-induced otitis media with effusion (RTOME) is associated with cancer type and radiation exposure to specific regions, according to a study published online March 29 in the Ear, Nose & Throat Journal.
April 7, 2025 — Source

Scientists pioneer noninvasive 3D imaging to enhance skin cancer management
Researchers from the Agency for Science, Technology and Research (A*STAR) and the National Healthcare Group (NHG) have jointly pioneered an innovative imaging technique combining Multispectral Optoacoustic Tomography (MSOT) with artificial intelligence that could significantly improve the diagnosis and treatment of basal cell carcinoma (BCC), the most common form of skin cancer worldwide.
April 7, 2025 — Source

Study links frailty to five-year mortality rate among older women with breast cancer
A new study links changes in frailty, a measure of decreased physiological capacity that leads to fatigue, slow walking, muscle weakness, physical inactivity, and weight loss, to five-year survival rates in older women with breast cancer. These findings suggest that managing frailty during chemotherapy could improve outcomes.
April 7, 2025 — Source

Test predicts which patients with prostate cancer most likely to develop long-term side effects from radiation therapy
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have validated a test that can accurately predict which patients with prostate cancer are at higher risk of developing long-lasting urinary side effects after receiving radiation therapy.
April 7, 2025 — Source

This Bill Aims To Help Firefighters With Cancer. Getting It Passed Is Just the Beginning.
As firefighters battled the catastrophic blazes in Los Angeles County in January, California's U.S. senators, Adam Schiff and Alex Padilla, signed onto legislation with a simple aim: Provide federal assistance to first responders diagnosed with service-related cancer.
April 7, 2025 — Source

UCSF creates a powerhouse AI system that boosts oncology care
The University of California at San Francisco's overarching goal was not to replace human judgment but to enhance it -- allowing oncologists to focus on personalized treatment rather than spending valuable time retrieving and verifying information.
April 7, 2025 — Source

Health — Cancer — April 2nd, 2025

Cancer patients from migrant backgrounds have a 1 in 3 chance of something going wrong in their care
More than 7 million people in Australia were born overseas. Some 5.8 million people report speaking a language other than English at home.
April 2, 2025 — Source

Combination approach to advanced cancer could improve survival
An international team of researchers, including experts from the University of Adelaide, has found genomic testing and targeted therapies for patients with advanced cancer could improve survival rates by up to 40%.
April 2, 2025 — Source

Common photosensitizing drugs increase skin cancer risk, study indicates
Some commonly prescribed photosensitizing drugs increase skin cancer risk, according to a study published online March 18 in Photodermatology, Photoimmunology & Photomedicine.
April 2, 2025 — Source

High-fat diet linked to increased breast cancer metastasis risk
Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs -- metastasize --. But the causes of this association are still not well understood. Researchers at the Spanish National Cancer Research Center (CNIO) have now provided new data by discovering that a high-fat diet activates mechanisms that facilitate metastasis.
April 2, 2025 — Source

Liver transplants offer new hope for colorectal cancer patients with liver metastasis
Liver transplants are becoming a new treatment option for certain colorectal cancer patients whose cancer has spread to their liver and are ineligible for other surgical options. This innovative approach is providing hope to colorectal cancer patients who are otherwise often faced with a grim prognosis.
April 2, 2025 — Source or Source

Mutated blood cells define clinical risks in Langerhans cell histiocytosis
A nationwide team led by researchers at Baylor College of Medicine, Texas Children's Hospital and UPMC Children's Hospital of Pittsburgh has proposed a major revision to how Langerhans cell histiocytosis (LCH) is diagnosed and treated after analyzing patients with LCH for several years.
April 2, 2025 — Source

Researcher uncovers how dietary fat may fuel cancer growth: Q&A
Estela Jacinto, a professor of biochemistry and molecular biology at Rutgers Robert Wood Johnson Medical School, has been studying a crucial pathway for human cell growth and metabolism for more than two decades.
April 2, 2025 — Source

Researchers explore the high incidence of colorectal cancer in Appalachian Kentucky
Researchers at the University of Kentucky analyzed different factors that could explain the high mortality rates of colorectal cancer in Appalachian Kentucky.
April 2, 2025 — Source

Scientists identify key protein driving ovarian cancer spread
A new study has identified the protein ADAMTS5 as playing a crucial role in the spread of ovarian cancer cells, offering a potential new target for future treatments.
April 2, 2025 — Source

Health — Cancer — March 31st, 2025

Cancer cell migration research offers hope for new treatment of brain tumors
University of Huddersfield scientist, Dr. Anke Brüning-Richardson, has published promising findings from the past seven years of research into a new approach for the treatment of highly aggressive brain tumors.
March 31, 2025 — Source

Cancer cells 'hacked' to expose themselves to immune attack
When your social media account starts spewing out nonsensical or threatening status updates, it's safe to assume that it has been hacked and must be shut down.
March 31, 2025 — Source

FDA approves cabozantinib for previously treated advanced neuroendocrine tumors
The U.S. Food and Drug Administration has approved cabozantinib (Cabometyx), an oral tyrosine kinase inhibitor, for patients with previously treated advanced neuroendocrine tumors, offering a new standard of care for this patient group, according to a press release from the Dana-Farber Cancer Institute.
March 31, 2025 — Source

Helping patients with gastroesophageal cancer avoid unnecessary chemotherapy
A Peter Mac-led international clinical trial has found a way to personalize treatment for gastroesophageal cancer, identifying patients who could avoid further intensive rounds of chemotherapy while they recover from surgery. Each year more than 1,700 Australians are diagnosed with gastroesophageal cancer, which has a five-year survival rate of less than 25%.
March 31, 2025 — Source

Readers Shop for Nutritional Information and Weigh Radiation and Cancer Risks
Great article ("How the FDA Opens the Door to Risky Chemicals in America's Food Supply," March 10). Another topic that needs more research is the fact that the FDA allows glysophate to be sprayed on wheat for human consumption to kill it off before harvest. It is then harvested seven days later and processed for food. In beans and corn, it is applied months before the food portion is developed, so it's not as big of a concern. The question would be: How much residual glyphosate is still in the wheat when harvested? Does the FDA know, or care? What are the health ramifications?
March 31, 2025 — Source

Health — Cancer — March 28th, 2025

AI in colonoscopy: Study finds increase in polyp detection but minimal cancer risk impact
A team of Norwegian researchers, through international collaboration, found that the use of artificial intelligence (AI) during colonoscopy increased the detection of polyps by about 8%, but the risk of cancer was minimally affected.
March 28, 2025 — Source

AI meets oncology: New model personalizes bladder cancer treatment
Leveraging the power of AI and machine learning technologies, researchers at Weill Cornell Medicine developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy. The model harnesses whole-slide tumor imaging data and gene expression analyses in a way that outperforms previous models using a single data type.
March 28, 2025 — Source

AI-powered model improves prediction of bladder cancer treatment outcomes
Leveraging the power of AI and machine learning technologies, researchers at Weill Cornell Medicine developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy. The model harnesses whole-slide tumor imaging data and gene expression analyses in a way that outperforms previous models using a single data type.
March 28, 2025 — Source

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer, study shows
Researchers at Baylor College of Medicine showed that lipid accumulation in tumor cells and nearby immune cells promotes immune suppression, but disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.
March 28, 2025 — Source

How melanoma and other tumors succeed in hiding and resisting immunotherapy
Cutaneous melanoma, the most aggressive form of skin cancer, is characterized by its accumulation of a large number of mutations. Although some of these alterations should be recognized as a threat by our defenses, melanomas often escape immune system surveillance. As a result, more than half of patients do not generally respond to current immunotherapies. Understanding and avoiding this phenomenon is one of the greatest challenges in oncology today.
March 28, 2025 — Source

Interval cancers account for significant breast cancer cases
In a new study, researchers from Karolinska Institutet have shown that so-called interval cancers, which are detected between two screening sessions, account for a significant proportion of breast cancer cases and that certain risk factors may increase the likelihood of developing this type of cancer.
March 28, 2025 — Source

Lipid accumulation in tumors linked to therapy resistance in breast cancer
A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy. Researchers at Baylor College of Medicine showed that lipid accumulation in tumor cells and nearby immune cells promotes immune suppression, but disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.
March 28, 2025 — Source

Researchers identify potential drug combinations to improve breast cancer treatment: Q&A with professor of pharmacology
To overcome that, some cancers, such as TNBC, can be treated with immune checkpoint inhibitors, which inhibit checkpoint proteins that cause T-cell exhaustion and allow them to continue to attack tumor cells.
March 28, 2025 — Source

Study shows virtual reality headsets may help ease cancer pain
A small group of cancer patients reported a decrease in their pain after using VR headsets that allowed them to explore realistic underwater scenes, according to findings published in the journal Scientific Reports.
March 28, 2025 — Source

Study suggests exercise could reduce breast cancer recurrence
Exercise could potentially reduce the recurrence rate of breast cancer, new research from Edith Cowan University (ECU) has found.
March 28, 2025 — Source

Supercomputer uncovers immune system's secret to self-tolerance
Researchers from the La Jolla Institute for Immunology recently used the Expanse supercomputer at the San Diego Supercomputer Center (SDSC), which is a pillar of the School of Computing, Information and Data Sciences (SCIDS) at UC San Diego, to better understand how cancer tumors react when the immune system is used to combat them.
March 28, 2025 — Source

Surgery may not be necessary to treat invasive breast cancer
Surgery may not be the best next course of treatment for patients with early-stage breast cancer who had a complete response to neoadjuvant (pre-surgical) chemotherapy and standard radiation treatment, according to new data from researchers at The University of Texas MD Anderson Cancer Center.
March 28, 2025 — Source

Health — Cancer — March 24th, 2025

AI 'fingerprint' technology could bring cancer drugs to patients in half the current time
Scientists have developed a revolutionary AI "fingerprint" technology that can accurately show how cancer cells respond to new drugs, by simply observing changes to their shape.
March 24, 2025 — Source

As stomach cancer rates rise in younger people, knowing symptoms and family history is key
Stomach cancer rates in the United States have been steadily decreasing for decades, but recent trends reveal an increase in early-onset stomach cancer in people younger than 50, particularly women. Trends also reveal younger people have more advanced stomach cancer at the time of diagnosis.
March 24, 2025 — Source

Citrus remedy squeezes out dry mouth for cancer patients
A natural citrus oil from oranges, lemons and limes is proving highly effective in relieving dry mouth, and when combined with a new lipid formulation, new research suggests it may be effective without significant side effects.
March 24, 2025 — Source

Genetically modified natural killer cells show promise in cancer immunotherapy
Among other functions, the NK cells (natural killers, a type of lymphocyte forming part of the immune system) have the capacity to detect and eliminate cancer cells. But in some cases they cannot overcome the tumor's defense mechanism and the cancer grows.
March 24, 2025 — Source

Magnetic nanoparticles transport drugs deep into tumors to slow cancer growth
A team of bioengineers at the University of Pennsylvania transported therapeutic nanoparticles, featuring magnetic cores, into the depths of tumors by tugging at them with an external magnetic device. Working in a mouse model of triple-negative breast cancer, the researchers used their approach to slow tumor growth far more than treatment with nanoparticles not exposed to a magnetic field.
March 24, 2025 — Source

Micro-ultrasound proves as effective as MRI in prostate cancer diagnosis
Biopsies guided by high resolution ultrasound are as effective as those using MRI in diagnosing prostate cancer, an international clinical trial has shown.
March 24, 2025 — Source

More pain, more gain? New biopsy technique found to improve prostate cancer detection
Researchers from around the U.K., led by the University of Oxford, have found that a new way of performing prostate biopsies is better at diagnosing prostate cancer, but takes longer to perform and is more painful for patients.
March 24, 2025 — Source

Nanotechnology could improve odds in treating aggressive breast cancers
Scientists are developing novel nanoparticles that could dramatically increase the effectiveness of immunotherapies when treating triple-negative breast cancer.
March 24, 2025 — Source or Source

New technique doubles erectile function preservation in prostate surgery
A technique to improve the precision of prostate cancer surgery means that almost twice as many men preserve their erectile function compared to those undergoing standard surgery, according to results from a clinical trial led by researchers from UCL and UCLH.
March 24, 2025 — Source

Simple urine test may spare kidney cancer patients from invasive scans
A simple urine test could accurately show the recurrence of kidney cancer at an early stage, potentially sparing patients invasive scans and enabling faster access to treatment, new research has shown.
March 24, 2025 — Source

Study uncovers key role of RNA modifications in prostate cancer progression
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m⁶A, plays a critical role in the progression of prostate cancer, including driving some of its most dangerous forms of the disease.
March 24, 2025 — Source

Trial reveals twice as many men recover erectile function after improved prostate cancer surgery
A technique to improve the precision of prostate cancer surgery means that almost twice as many men preserve their erectile function compared to those undergoing standard surgery, according to results from a clinical trial led by researchers from UCL and UCLH.
March 24, 2025 — Source

Urine test could halve post-op scans for kidney cancer
A simple urine test could accurately show the recurrence of kidney cancer at an early stage, potentially sparing patients invasive scans and enabling faster access to treatment, new research has shown.
March 24, 2025 — Source

Waist circumference identified as a stronger cancer risk marker in men
Body size and excess weight, conventionally assessed using body mass index (BMI), are well-established risk factors for many types of cancer. However, new research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of the National Cancer Institute shows that waist circumference (WC) is a stronger risk marker than BMI for developing obesity-related cancers in men, but not women. The study was conducted by Dr Ming Sun, Dr Josef Fritz and Dr Tanja Stocks, Lund University, Malmö, Sweden, and colleagues.
March 24, 2025 — Source

Younger adults at increased risk for colon cancer
Colon cancers have been steadily increasing among people younger than 50, even as cases have declined among seniors.
March 24, 2025 — Source

Health — Cancer — March 21st, 2025

AI shows how drugs affect ovarian cancer cells
In a study on ovarian cancer cells, researchers from Karolinska Institutet demonstrate how the tumor environment influences how cancer cells respond to drugs by using AI.
March 21, 2025 — Source

Glioblastoma trial design is expanding and becoming more suited to clinical practice
Researchers at the University of Tsukuba have investigated the changes in the primary evaluation items in phase II clinical trials for glioblastoma, a type of brain tumor. Recently, the items have become more diverse, with more time-to-event indicators such as survival time being used, whereas the use of response rate, which indicates the proportion of patients whose cancer has shrunk, has decreased. These changes indicate that the design of trials is becoming more comprehensive and more adapted to clinical practice.
March 21, 2025 — Source

How stem cells calm the body's immune response
The results yielded a surprise: Even stem cells possess surface proteins that enable them to suppress the activation of inflammatory and immune responses in the body. This finding is particularly relevant for stem cell transplants, applied for the treatment of, for example, leukemia.
March 21, 2025 — Source

Novel oral drug therapy combination shows promise for advanced melanoma patients
A research team led by Sheri Holmen, Ph.D., investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new combination drug therapy that could both treat and prevent melanoma metastasis, or spreading from its original site, to the brain.
March 21, 2025 — Source

Researchers learn how a drug called zotatifin kills cancer cells
Swirling inside every cell are millions of microscopic messages called messenger RNAs (mRNAs). The messages are the genetic blueprints for proteins, which determine the behavior and health of the cell.
March 21, 2025 — Source

Research reveals worse outcomes for men who avoid prostate cancer screening
Men who consistently avoid prostate cancer screening appointments face a disproportionately higher risk of dying from the disease, finds research identifying a new high-risk group.
March 21, 2025 — Source

Silk sponges instead of animal testing: How a 3D cell culture system could advance cancer diagnostics
A consortium of Austrian research groups from the University of Vienna, MedUni Vienna and Technikum Wien, together with company partner DOC Medikus GmbH, has developed an innovative bioanalytical test system for radiopharmaceutical drug candidates for cancer diagnosis and therapy.
March 21, 2025 — Source

Study suggests cheap health insurance can delay cancer diagnosis, increase risk of death
Considering a short-term health insurance plan as a cheap alternative to more costly comprehensive coverage?
March 21, 2025 — Source

Tattoos Could Be a Hidden Cancer Risk, Study of Twins Finds
Twins who got tattoos had a higher risk of being diagnosed with skin cancer and lymphoma.
March 21, 2025 — Source

Warning signs of colorectal cancer in younger adults
Colorectal cancer, the third-most common cancer in the U.S., has been rising among younger people for the past two decades. It is not one type of cancer but two cancers: colon cancer, which starts in the large intestine, and rectal cancer, which begins in the last part of the large intestine, known as the rectum.
March 21, 2025 — Source

Health — Cancer — March 17th, 2025

A post-treatment blood test could inform future cancer therapy decisions
In the continuing evolution of personalized medicine, a new Yale study has found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer years after their treatment.
March 17, 2025 — Source

AI diagnoses endometrial cancer with near perfect accuracy
One of Australia's most common gynecological cancers could be detected sooner and more accurately thanks to a specialized artificial intelligence (AI) model, new research shows.
March 17, 2025 — Source

Alcohol and cancer risk: What we know
Most people know about the connection between cigarettes and cancer risk, but does drinking cause cancer? It's something rarely discussed, despite years of evidence that alcohol increases cancer risk.
March 17, 2025 — Source

Are colon and rectal cancers treated differently?
Colorectal cancer is a term that combines both colon and rectal cancers. The colon and rectum are two different parts of the lower digestive tract. These different cancers also mean different approaches to treatment that may involve the use of radiation and chemotherapy in addition to surgery.
March 17, 2025 — Source

Cancer nanotech nurtures sustainable agriculture innovation
Cancer drugs and agrichemicals can be powerful, but toxic, tools. Now, UNSW scientists are applying nanomedicine insights in a project to make greener agrichemicals more affordable.
March 17, 2025 — Source or Source

Drug found 'remarkably' effective in common canine oral cancer
Dogs that have oral squamous cell carcinomas often need surgery that disfigures their jaws and lower their quality of life—and in 20% of dogs diagnosed, the cancer has metastasized to a point where surgery is no longer an option.
March 17, 2025 — Source

Early detection of colon cancer is critical for women
Colon cancer is one of the most dangerous cancers affecting women today.
March 17, 2025 — Source

Early palliative care billing up from 2010 to 2019 for advanced cancer
For patients with distant-stage cancers, there was an increase in early palliative care (PC) billing from 2010 to 2019, but the level remained low, according to a study published in the Journal of Clinical Oncology.
March 17, 2025 — Source

Fewer deaths, new substances and evolving treatments in Philly's opioid epidemic: Four essential reads
In Philadelphia, fatal overdoses are the No. 3 cause of death after heart disease and cancer. That's been the case each year since 2016, except in 2020 and 2021 when COVID-19 deaths outpaced overdose deaths. The vast majority of fatal overdoses in Philly involve the synthetic opioid fentanyl.
March 17, 2025 — Source

Micro metal-movers: Biochemists are one step closer to better cancer treatments
By unraveling the complex choreography of cellular machinery, Michigan State University researchers are helping identify the next generation of drug targets and cancer therapies.
March 17, 2025 — Source

Neuropeptide Y identified as key driver of pancreatic cancer spread
Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolism 'switch' to help it spread, revealing a potential new treatment strategy for this highly aggressive disease.
March 17, 2025 — Source

New research reveals potential path forward for glioblastoma treatment
Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy. But new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, suggests a way forward: suppressing a protein called ZNF638 triggers an antiviral immune response, making immune checkpoint inhibitors more effective. The discovery not only offers a potential new treatment strategy but also identifies ZNF638 as a biomarker that could help personalize immunotherapy for patients.
March 17, 2025 — Source

Newborns with heart defects may face a higher risk of developing childhood cancer
Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published in Circulation.
March 17, 2025 — Source

Personalized cancer vaccine proves promising in a phase 1 trial
Researchers at the Icahn School of Medicine at Mount Sinai, led by Nina Bhardwaj, MD, Ph.D., Ward-Coleman Chair in Cancer Research and Director of the Vaccine and Cell Therapy Laboratory, have tested a promising new type of personalized multi-peptide neoantigen cancer vaccine, called PGV001, in a small group of patients.
March 17, 2025 — Source

Prion protein may play key role in progression of glioblastoma
Glioblastoma (GBM), one of the most aggressive types of brain cancer, is one of the greatest challenges for medicine, both because it is difficult to treat and because of its high mortality rate. In Brazil, although no exact figures are available, it is estimated that between 10,000 and 12,000 new cases are diagnosed every year.
March 17, 2025 — Source

Radiotherapy alone following hysterectomy should remain standard of care for early-stage cervical cancer: Trial
Results from the NRG Oncology GOG-0263 Phase III clinical trial testing the addition of cisplatin-based chemotherapy to adjuvant radiotherapy following radical hysterectomy and lymphadenectomy for patients with early-stage, intermediate-risk cervical carcinoma indicated that the addition of chemotherapy did not improve outcomes for patients and led to increased toxicity for patients.
March 17, 2025 — Source

Reprogramming Liver Immunity: A Lipid Nanoparticle Approach for Pancreatic Cancer Therapy
A recent study published in ACS Nano explored a novel strategy to reprogram the liver's immune environment and generate an antitumor response against metastatic pancreatic cancer.
March 17, 2025 — Source

Researchers move closer to a functional cure for chronic hepatitis B
Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma. Despite widespread vaccination and antiviral treatments, millions of people still suffer from chronic hepatitis B virus (HBV) infection. The primary challenge in curing the disease lies in the persistence of covalently closed circular DNA (cccDNA), a stable viral DNA form that resides in the nucleus of infected liver cells. Current therapies, such as nucleos(t)ide analogues and interferons, fail to eliminate cccDNA, allowing the virus to rebound after treatment is stopped.
March 17, 2025 — Source

Unexpected discovery shows how cells use telomeres to avoid cancer
Cancer researchers at Children's Medical Research Institute have discovered an "unexpected mechanism" that our cells use to avoid cancer.
March 17, 2025 — Source

Yale research supports MRD detection for post-treatment lung cancer care
In the continuing evolution of personalized medicine, a new Yale study has found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer years after their treatment.
March 17, 2025 — Source

Suppressing key protein may unlock immunotherapy for glioblastoma
Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy. But new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, suggests a way forward: suppressing a protein called ZNF638 triggers an antiviral immune response, making immune checkpoint inhibitors more effective.
March 17, 2025 — Source

Health — Cancer — March 14th, 2025

A metabolic 'switch' that could help stop the spread of pancreatic cancer
Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolic "switch" to help it spread, revealing a potential new treatment strategy for this highly aggressive disease.
March 14, 2025 — Source

Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center. The results, published in Cancer Discovery, prime the combination strategy for future clinical trials.
March 14, 2025 — Source

Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer
Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center. The results, published in Cancer Discovery, prime the combination strategy for future clinical trials.
March 14, 2025 — Source

New therapeutic approach shows promise for pediatric high-grade gliomas
Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options. A research team from MedUni Vienna/University Hospital Vienna, the Dana-Farber Cancer Institute and the University of Michigan Medical School identified Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) as a promising therapeutic approach. The study has just been published in the scientific journal "Cancer Cell".
March 14, 2025 — Source

Pitt study uncovers a novel trigger of deadly form of ovarian cancer
Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.
March 14, 2025 — Source

Study reveals new insights into the origins of ovarian cancer
Researchers at the University of Pittsburgh have identified a novel trigger for a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.
March 14, 2025 — Source

Unveiling cancer's hidden messengers: How extracellular vesicles aid tumor spread
Most cells in the body send out little messengers called extracellular vesicles that carry proteins, lipids, and other bioactive molecules to other cells, playing an important role in intercellular communication. But healthy cells are not the only ones that rely on extracellular vesicles. Cancer cells do, too. Small extracellular vesicles that are shed from tumor cells contribute to how cancer spreads to healthy tissue.
March 14, 2025 — Source

Health — Cancer — March 13th, 2025

Adding a deadline to bowel screening invitation letters boosts test returns, study shows
Researchers have found that adding a deadline to bowel screening invitation letters boosted test returns, with the largest effect for a 2-week return deadline.
March 13, 2025 — Source

Already approved drug avapritinib shows promise in treating high-grade gliomas
High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence and difficulty for drugs to cross the blood-brain barrier.
March 13, 2025 — Source

Checking PSA levels too soon after prostate cancer surgery can lead to overtreatment, study suggests
After surgical removal of the prostate to treat prostate cancer, clinicians monitor prostate specific antigen (PSA) levels. Persistently elevated PSA levels indicate residual cancer and are linked to worse outcomes.
March 13, 2025 — Source

Combination immunotherapy before surgery may increase survival in people with head and neck cancer: Clinical trial
Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug.
March 13, 2025 — Source or Source

Developing portable, blood-based device that detects colon cancer
No one looks forward to a colonoscopy. The procedure, which is used to screen for colorectal cancers, is unpleasant and costly and can lead to medical complications. But screening for the cancer is critical; colon cancer is the second leading cause of cancer-related death in the U.S., according to the National Cancer Institute.
March 13, 2025 — Source

Eat better, breathe easier? Research points to link between diet, lung cancer
For cancers of organs like the liver, the long-term impact of our diet has been well studied—so much so that we have guidance about red meat, wine and other delicacies.
March 13, 2025 — Source

Exercise key to improving sexual dysfunction for patients with prostate cancer, study says
New research from Edith Cowan University (ECU) has confirmed that erectile dysfunction in patients living with prostate cancer could be significantly improved through regular exercise.
March 13, 2025 — Source

New guideline on gastric premalignant cancer
The American College of Gastroenterology has published its first clinical guideline on the diagnosis and management of gastric premalignant conditions (GPMC), which have an increased risk of progression to gastric cancer and include atrophic gastritis, gastric intestinal metaplasia, dysplasia, and certain gastric epithelial polyps.
March 13, 2025 — Source

New study refines cancer risk assessment for Li-Fraumeni syndrome
People with the rare Li-Fraumeni syndrome (LFS) have a high risk of developing cancer. Almost all those affected will develop cancer once, and in many cases several times, during their lifetime. LFS is a hereditary disease caused by disease-relevant variants in the TP53 gene.
March 13, 2025 — Source

Proteins identified as key players in immunotherapy resistance for colorectal cancer
A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, the team identified specific proteins - fibronectin and smooth muscle actin - within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.
March 13, 2025 — Source

Repurposed FDA-approved drug could help treat high-grade glioma
High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence and difficulty for drugs to cross the blood-brain barrier.
March 13, 2025 — Source

RNA molecule identified as possible driver of gastric cancer
Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer—among the world's deadliest forms of the disease.
March 13, 2025 — Source

Specific proteins are linked to immunotherapy resistance in metastatic colorectal cancer
A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, the team identified specific proteins—fibronectin and smooth muscle actin—within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.
March 13, 2025 — Source

Targeting MARCO enhances cancer immunotherapy effectiveness
Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO. Their study, published in the Journal for ImmunoTherapy of Cancer, shows that blocking MARCO in combination with a type of immunotherapy known as anti-CTLA4 therapy, significantly enhances tumor regression in melanoma, the deadliest form of skin cancer.
March 13, 2025 — Source

Health — Cancer — March 12th, 2025

Blind to the burn: Misconceptions about skin cancer risk in the US
Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs the U.S. approximately $8.9 billion annually.
March 12, 2025 — Source

Discovery of metabolic link to immune protein suppression offers new therapeutic avenues
Not long after a threatening organism enters our bodies, our immune system springs into action and starts producing proteins known as type one interferons (IFN-I), which fight viruses and cancer, while also playing pathogenic roles in autoimmune disorders.
March 12, 2025 — Source

Gaps in HPV cancer screening and prevention identified for people living with HIV
A new study published in The Lancet HIV reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities. A literature review, conducted by a team of international experts underscores the need for further research and highlights existing disparities in healthcare for this vulnerable population.
March 12, 2025 — Source

Lighting the way: How activated gold nanoparticles reveal drug movement in the body
Tracking targeted drug delivery is often a challenge due to limitations in current imaging techniques. A recent study by Tokyo's Waseda University reports a breakthrough imaging technique that allows direct and highly sensitive tracking of gold nanoparticles (AuNPs) inside the body. This novel technique, which uses neutron activation of gold, could revolutionize cancer drug delivery by enabling real-time visualization of the gold nanoparticles without external tracers.
March 12, 2025 — Source

Scientists identify lncRNA as potential biomarker and therapeutic target for hepatocellular carcinoma
Hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths worldwide, remains one of the most aggressive malignancies. In a recent study published in Nature Communications, researchers led by Profs. Yang Pengyuan and Chen Runsheng from the Institute of Biophysics of the Chinese Academy of Sciences have uncovered a novel mechanism by which tumor-derived long noncoding RNA (lncRNA) suppresses anti-tumor immunity, providing new insights into the role of extracellular vesicles (EVs) in HCC progression.
March 12, 2025 — Source

Some CT Scans Deliver Too Much Radiation, Researchers Say. Regulators Want To Know More.
Rebecca Smith-Bindman, a professor at the University of California-San Francisco medical school, has spent well over a decade researching the disquieting risk that one of modern medicine's most valuable tools, computerized tomography scans, can sometimes cause cancer.
March 12, 2025 — Source

Study reveals crucial gaps in oral cancer awareness in Middle East and North Africa
An international research team, including Associate Professor Omar Kujan from The University of Western Australia's Dental School, assessed the knowledge of oral cancer risk factors, symptoms and protective measures among 4,197 participants.
March 12, 2025 — Source

Targeted alpha therapy offers new hope for treating metastatic melanoma
Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms of skin cancer, with current therapies—including immunotherapy and targeted drugs—showing limited effectiveness. Radiotherapy is an emerging treatment for melanoma, but conventional beta-emitting radionuclide therapies have limitations due to their low energy transfer and long-range radiation, which can cause unintended damage to healthy tissues.
March 12, 2025 — Source

Targeted alpha therapy: Advances in treating refractory skin cancer
Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms of skin cancer, with current therapies—including immunotherapy and targeted drugs—showing limited effectiveness.
March 12, 2025 — Source

The secret DNA circles fueling pancreatic cancer's aggression
Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems from both late detection and the cancer's notorious capacity to adapt and resist therapy.
March 12, 2025 — Source

Transforming thymic carcinoma treatment with a dual approach
Thymic epithelial tumors are a rare group of malignancies originating in the thymus gland, that includes thymoma and thymic carcinoma. Among these, thymic carcinoma is the more aggressive subtype, characterized by high invasiveness, metastatic potential, and poor prognosis.
March 12, 2025 — Source

Health — Cancer — March 11th, 2025

Beneficial genetic changes observed in regular blood donors
Researchers at the Francis Crick Institute have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells.
March 11, 2025 — Source

Genomic study reveals important similarities and differences in ovarian cancer mutations across populations
An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black women have nearly identical mutations to other previously studied populations. But researchers also found a few notable differences that may be clinically relevant.
March 11, 2025 — Source

Experiments aboard the International Space Station may offer promising advancements in fighting cancer
Getting seven experiments on the International Space Station requires a really good idea. Like a brand new way to attack tumors—one that you can only make in space.
March 11, 2025 — Source

How wildfires pose challenges to cancer care
Due to the physical, psychological, and socioeconomic consequences of a cancer diagnosis and treatment, people with cancer are especially vulnerable during extreme weather events like hurricanes, tornadoes, and wildfires, which are becoming more common and damaging with climate change.
March 11, 2025 — Source

Nwd1 gene deletion triggers MASH-like pathology in mice
Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns. It is prevalent in 30% of the population worldwide and poses a risk of advancing to cirrhosis and liver cancer.
March 11, 2025 — Source

The 'colocatome': Scientists create a catalog of non-cancerous cells' influence on cancer
Even cells experience peer pressure. Scientists have long studied the ins and outs of cancer cells to learn more about the disease, but they're increasingly finding that noncancerous cells near the cancer cells exert a powerful influence over a tumor's trajectory.
March 11, 2025 — Source

Health — Cancer — March 10th, 2025

AI reduces false positives by 37.3% in breast cancer diagnosis
Despite making up half of the global population, women's health has often been sidelined by traditional health care systems. Systemic neglect has led to delayed diagnoses and inadequate care. Artificial intelligence (AI) is emerging as a transformative force in women's health care, enhancing clinical decision-making, improving diagnostic accuracy, and guiding treatments for better outcomes.
March 10, 2025 — Source

Breakthrough drug combination targets KRAS mutation in lung cancer
A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib-an FDA-approved drug in the market-and an experimental drug called FGTI-2734, which could make precision medicine more effective for patients with a highly resistant form of lung cancer.
March 10, 2025 — Source or Source

Firefighters face a higher brain cancer risk associated with gene mutations caused by chemical exposure, study suggests
Gene mutations caused by exposure to certain chemical compounds have been linked to the development of gliomas, the most common type of malignant brain tumor. New research reveals that among patients with gliomas, these mutations are more common in firefighters than in individuals with other occupations.
March 10, 2025 — Source

Florida leukemia rates rising rapidly as population ages
Driven by a steady influx of retirees, Florida now has the highest leukemia rates of any U.S. state and the disease is the fastest-rising cancer type statewide, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.
March 10, 2025 — Source

Is red wine a healthier choice than white wine? Epidemiologists uncork the cancer risks
A common perception is that not all alcoholic beverages are alike. Red wine, for instance, is often considered a healthier choice, with many believing its high resveratrol content—an antioxidant with anti-inflammatory properties—offers protection against cancer. Researchers from the Brown University School of Public Health, however, have put this assumption to the test.
March 10, 2025 — Source

Long visit in the ER? It's a good time to learn about cervical cancer screening
A University of Rochester Medical Center study showed that downtime in the emergency room can have a potential upside for women who are behind on cervical cancer screenings, which is a nationwide problem.
March 10, 2025 — Source

Nanoparticle sensor enables precision timing of light-based cancer treatment
Light can destroy cancer cells, but only if drugs activated by that light are present in sufficient quantities within the tumor. This seemingly simple requirement has complicated photodynamic therapy since its inception. Without a way to directly measure drug activation and cell death, doctors must estimate when to shine light on tumors based on approximate drug accumulation times. These estimates often lead to mistimed treatments - either too early when insufficient drug is present, or too late when the opportunity for maximum impact has passed.
March 10, 2025 — Source

New CAR-T cell therapy 'ALA-CART' shows promise for hard-to-treat cancers
Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against cancer cells that are harder for prior CAR-T therapies to detect and fight.
March 10, 2025 — Source

New supercharged CAR-T cell therapy shows promise against resistant cancers
Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against cancer cells that are harder for prior CAR-T therapies to detect and fight.
March 10, 2025 — Source

Risk for specific hematologic cancers down with GLP-1 receptor agonist use in type 2 diabetes
For patients with type 2 diabetes (T2D), glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is associated with a reduced risk for developing hematologic cancers compared with insulin and metformin use, according to a research letter published online March 6 in JAMA Network Open.
March 10, 2025 — Source

Scientists identify new strategy to fight cancer caused by Epstein-Barr virus
The Wistar Institute's Paul M. Lieberman, Ph.D. and lab identified and tested a new method for targeting certain cancers caused by Epstein-Barr Virus (EBV), in the paper, "USP7 inhibitors destabilize EBNA1 and suppress EBV tumorigenesis," from the Journal of Medical Virology.
March 10, 2025 — Source

Study confirms link between breast density, higher breast cancer risk
A new study confirms that breast density plays a significant role in both the risk of breast cancer diagnosis and the sensitivity of mammography, which may affect screening practices.
March 10, 2025 — Source

Study links firefighting chemicals to increased glioma risk
A new study uncovered an association between exposure to chemicals commonly used in firefighting and glioma risk, reinforcing earlier research that has suggested a link between firefighting and the development of cancers.
March 10, 2025 — Source

Walking, moving more may lower risk of cardiovascular death for women with cancer history
Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.
March 10, 2025 — Source

Health — Cancer — March 9th, 2025

New research shows bigger animals get more cancer, defying decades-old belief
A longstanding scientific belief about a link between cancer prevalence and animal body size has been tested for the first time in our new study ranging across hundreds of animal species.
March 9, 2025 — Source

Health — Cancer — March 8th, 2025

Circular RNA plays key role in cancer biology and therapy
A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies. Once thought to be noncoding RNA, circRNA has now been shown to encode functional proteins, challenging conventional RNA biology and opening up novel therapeutic possibilities.
March 8, 2025 — Source

Does Ozempic Really Cause Thyroid Cancer? What the Science Actually Says
Recent research throws into question whether GLP-1 drugs increase the risk of certain types of thyroid cancer.
March 8, 2025 — Source

EZH2 inhibition offers hope for fighting treatment-resistant cancers
The critical role of EZH2, an essential epigenetic regulator, in cancer progression and treatment is underscored in this new review article published in Genes & Diseases. The study highlights the transformative potential of EZH2 inhibition, paving the way for a new generation of targeted therapies aimed at disrupting tumor growth and overcoming treatment resistance.
March 8, 2025 — Source

New research shows bigger animals get more cancer, defying decades-old belief
Larger species face higher cancer risks but those that reached that size rapidly evolved mitigating mechanisms.
March 8, 2025 — Source

Study explores methods to enhance cancer-gene testing in clinics
Up to 10% of cancers are caused by genes that can be easily detected by commercially available tests. These include such common cancers as cancer of the breast, ovary, colon, stomach, uterus and pancreas.
March 8, 2025 — Source

Ubiquitination plays a key role in cancer stem cell function and treatment resistance
This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance. Published in Genes & Diseases, this article explores the intricate mechanisms through which the ubiquitin (Ub) system regulates key pathways essential for CSC maintenance and survival.
March 8, 2025 — Source

Unraveling the genetic differences between LUAD and LUSC in lung cancer
Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) representing the most prevalent subtypes of non-small cell lung cancer (NSCLC). Despite their classification under the same umbrella, these two forms of lung cancer exhibit distinct genetic landscapes, therapeutic targets, and treatment responses.
March 8, 2025 — Source