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125 Health - Parkinson's Disease Resources

Misc. - Numbers

'5-D protein fingerprinting' with nanopores could give insights into Alzheimer's, Parkinson's
In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid.
January 17, 2017
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23andMe is finally allowed to tell you if you have the genes for Parkinson's
The Food and Drug Administration finally gave 23andMe a long sought-after green light today to sell to consumers genetic tests and their accompanying health risk reports for up to 10 diseases, including late-onset Alzheimer's and Parkinson's.
April 6, 2017
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23andMe wins FDA approval to give customers health risk info
The gene testing company can now tell US customers who use its home DNA kit whether they have a genetic risk for any of 10 diseases and conditions.
April 6, 2017
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Misc. - A

A Brain Injection of Dna Could Help Control Parkinson's Disease Symptoms
Gene Therapy Would Make Drugs Effective Longer
August 22, 2016
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A cure for Parkinson's? Replacing damaged brain cells shows promise
Researchers may have brought us closer to a cure for Parkinson's disease, after finding a way to replace the brain cells destroyed by the disease.
April 11, 2017
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A Graphic Designer Rewrites Her Future with Parkinson's Disease
Today at Build, Microsoft's annual developer conference, chief executive officer Satya Nadella shared his vision for the future of technology. As part of the discussion, he emphasized the role that technology can play to empower people to achieve more and the importance of inclusive design to make sure technology leaves no one behind.
June 2, 2017
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Altmetric data analysis reveals how Parkinson's disease research affects the world
Scientists have published an analysis of Parkinson's disease research papers with the highest Altmetric Attention Scores. the publication is the first in a series aimed at utilizing Altmetric data to provide a more nuanced understanding of how the announcements of new medical discoveries affect the wide-range of disease-specific stakeholders including researchers, funders, care providers, and patients.
February 13, 2017
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Antibiotic doxycycline may offer hope for treatment of Parkinson's disease
Recent study suggests that doxycycline can be prescribed at lower doses for the treatment of Parkinson's disease
May 3, 2017
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Autoimmunity may have role in Parkinson's disease
For the first time, scientists have found evidence that autoimmunity may have a role in Parkinson's disease. They found that fragments of the protein that builds up in the dopamine cells of the brains of people with Parkinson's trigger an immune response that kills the cells.
June 21, 2017
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Misc. - B

Big trash pickup for cells
Cells are garbage pickers, carefully selecting the trash they want to keep or discard
August 1, 2016
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Biomarkers for cognitive impairment in Parkinson's revealed
Parkinson's disease affects about half a million people in the United States. New research identifies biomarkers that could predict the cognitive impairment typical of this neurodegenerative disease.
May 18, 2017
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Bowel cancer medication could help treat patients with early-onset Parkinson's disease, study suggests
People with certain forms of early-onset Parkinson's disease could potentially benefit from taking a medication used to treat certain forms of cancer, according to new research by University of Leicester scientists and funded by the Medical Research Council.
March 14, 2017
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Brain's immune cells linked to Alzheimer's, Parkinson's, schizophrenia
Scientists conducted a vast microglia survey, revealing links to neurodegenerative diseases and psychiatric illnesses.
May 31, 2017
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Breakthrough in production of dopamine neurons for Parkinson's disease
The first transplantation of stem cells in patients with Parkinson's disease is almost within reach, say investigators. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients.
October 28, 2016
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Build 2017: Microsoft's 'Project Emma' is a wearable for Parkinson's disease sufferers
Today at Build 2017, Microsoft unveiled many cool new technologies, but there was one particular announcement that truly touched the hearts of many in attendance. Called "Emma," it is a wrist wearable that can help people suffering with Parkinson's disease.
May 10, 2017
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Misc. - C

Can This New Non-Invasive Brain Stimulation Cure Parkinson's?
MIT researchers developed a new form of non-invasive deep brain stimulation that promises to be less risky, less expensive, and more accessible to patients.
June 8, 2017
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Cell disposal faults could contribute to Parkinson's, study finds
A fault with the natural waste disposal system that helps to keep our brain cell 'batteries' healthy may contribute to neurodegenerative disease, a new study has found.
January 24, 2017
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Correct connections are crucial
Individualizing deep brain stimulation in patients with Parkinson's disease
June 23, 2017
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Could Parkinson's disease start in the gut?
Parkinson's disease may start in the gut and spread to the brain via the vagus nerve, according to a study. the vagus nerve extends from the brainstem to the abdomen and controls unconscious body processes like heart rate and food digestion.
April 26, 2017
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CRISPR tech leads to new screening tool for Parkinson's disease
A team of researchers is using breakthrough gene-editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system. The technology allows scientists in the lab to 'light up' and then monitor a brain protein called alpha-synuclein that has been associated with Parkinson's.
June 5, 2017
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Misc. - D

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases
Rutgers scientists say neurodegenerative diseases like Alzheimer's and Parkinson's may be linked to defective brain cells disposing toxic proteins that make neighboring cells sick.
February 10, 2017
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Dementia not prevented with vitamin E, selenium, study finds
An ample body of research has shown that oxidative stress plays a key role in the development of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. as a result, antioxidant supplements have been proposed as preventive measures against dementia. a new trial, however, tests the effect of vitamin E and selenium on aging men and finds no evidence that they have therapeutic value.
March 19, 2017
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Diabetes drug slows experimental Parkinson's disease progression, human trials to begin next year
A new investigational drug originally developed for type 2 Diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of new research.
December 6, 2016
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Discovery of genetic 'switch' could help to prevent symptoms of Parkinson's disease
A genetic 'switch' has been discovered, which could help to prevent or delay the symptoms of Parkinson's disease, report scientists.
February 17, 2017
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DNA 'barcoding' allows rapid testing of nanoparticles for therapeutic delivery
Using tiny snippets of DNA as 'barcodes,' researchers have developed a new technique for rapidly screening the ability of nanoparticles to selectively deliver therapeutic genes to specific organs of the body. the technique could accelerate the development and use of gene therapies for such killers as heart disease, cancer and Parkinson's disease.
February 7, 2017
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Misc. - E

Emory scientists show how same enzyme spurs Alzheimer's and Parkinson's disease
Alzheimer's disease and Parkinson's disease are not the same. They affect different regions of the brain and have distinct genetic and environmental risk factors.
July 4, 2017
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Enzyme deficiency in Krabbe's disease may point to new mechanisms underlying Parkinson's disease
A new article suggests that an enzyme deficiency seen in the lysosomal storage disorder Krabbe's disease may point to new mechanisms underlying certain late-onset neurodegenerative diseases such as Parkinson's disease.
September 19, 2016
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Exercise May be Real Medicine for Parkinson's
Physical activity helps improve gait and balance, research review finds
December 22, 2016
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Misc. - G

Gene mutation appears to increase risk of Parkinson's disease in Caucasians
A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. the effect is particularly dramatic for people under age 50.
November 28, 2016
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Gene mutation linked to early onset of Parkinson's disease in caucasians
A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research. the effect is particularly dramatic for young-to-middle-age adults.
November 28, 2016
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Genetic variants linked to higher BMI may be protective against Parkinson disease
Genetic variants linked to higher body mass index (BMI) are associated with lower risk of Parkinson disease, according to a new study.
June 13, 2017
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Gut may play key role in preventing Parkinson's disease
Your gut may play a pivotal role in preventing the onset of Parkinson's disease. and the reason may be its knack for sleuthing.
October 5, 2016
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Gut microbe mix may spark Parkinson's
In mice, brain inflammation, motor problems linked to intestinal bacteria
December 1, 2016
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Gut microbes promote motor deficits in a mouse model of Parkinson's disease
Gut microbes may play a critical role in the development of Parkinson's-like movement disorders in genetically predisposed mice, researchers report. Antibiotic treatment reduced motor deficits and molecular hallmarks of Parkinson's disease in a mouse model, whereas transplantation of gut microbes from patients with Parkinson's disease exacerbated symptoms in these mice. the findings could lead to new treatment strategies for the second most common neurodegenerative disease in the United States.
December 1, 2016
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Misc. - H

Hand-grip test can indicate decline in physical function of Parkinson's patients
A basic hand-grip test has proven to be a reliable tool to monitor the decline of patients with Parkinson's diseases, say investigators.
February 1, 2017
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Hand-grip test proves to be easy, reliable way to examine muscle strength decline in PD patients
UBC researchers Jenn Jakobi and Gareth Jones, both Health and Exercise Sciences professors at UBC's Okanagan campus, recently completed a study that examined the methods used to monitor the progressive advancement of Parkinson's disease (PD)--a degenerative disease that affects the central nervous system.
February 1, 2017
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How this small wearable could help doctors spot Parkinson's earlier
The low-cost ENTy wearable, which has been tested on over 500 patients so far, seems to have a future helping diagnose people with balance issues.
September 15, 2016
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Misc. - I

Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease
Researchers at Johns Hopkins report they have identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal's brain – and a way to block that protein's action. Their study in mice and cultured cells suggests that an immunotherapy already in clinical trials as a cancer therapy should also be tested as a way to slow the progress of Parkinson's disease, the researchers say.
September 29, 2016
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IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets
Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure.
August 16, 2016
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Is It Parkinson's Disease? Blood Test Might Tell
But new technique needs more study, researchers say
February 8, 2017
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Misc. - L

Large-scale production of living brain cells enables entirely new research
Important pieces of the puzzle to understand what drives diseases such as Alzheimer's and Parkinson's are still missing today. One crucial obstacle for researchers is that it is impossible to examine a living brain cell in someone who is affected by the disease. With the help of a new method for cell conversion, researchers have found a way to produce diseased, aging brain cells on a large scale in a cell culture dish.
June 26, 2017
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Large-scale production of living brain cells enables entirely new research
Important pieces of the puzzle to understand what drives diseases such as Alzheimer's and Parkinson's are still missing today. One crucial obstacle for researchers is that it is impossible to examine a living brain cell in someone who is affected by the disease.
June 26, 2017
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Link between microbiome in the gut, Parkinson's discovered
Parkinson's disease, and medications to treat Parkinson's, have distinct effects on the composition of the trillions of bacteria that make up the gut microbiome, new research shows.
March 2, 2017
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Link between Parkinson's and melanoma runs both ways
A study published this week in Mayo Clinic Proceedings confirms that Parkinson's disease can, perhaps surprisingly, increase the risk of melanoma. The researchers also show that the link is a two-way relationship, with melanoma also suspected to increase the risk of Parkinson's.
July 4, 2017
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Low-fat dairy intake may raise Parkinson's risk
Low-fat dairy is often seen as a healthful alternative to the full-fat kind. But according to a new study, consuming higher amounts of low-fat dairy may raise the risk of Parkinson's disease.
June 8, 2017
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Misc. - M

Making brain implants smaller could eliminate scarring, extend life of devices
Many diseases, including Parkinson's disease, can be treated with electrical stimulation from an electrode implanted in the brain. However, the electrodes can produce scarring, which diminishes their effectiveness and can necessitate additional surgeries to replace them.
May 16, 2017
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Making brain implants smaller could prolong their lifespan
Thin fibers could be used to deliver drugs or electrical stimulation, with less damage to the brain
May 16, 2017
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Mayo Clinic study: Patients with Parkinson's have higher risk of melanoma and vice versa
People with the movement disorder Parkinson's disease have a much higher risk of the skin cancer melanoma, and vice versa, a Mayo Clinic study finds. While further research is needed into the connection, physicians treating one disease should be vigilant for signs of the other and counsel those patients about risk, the authors say.
July 4, 2017
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Mechanisms behind sensory deficits in Parkinson's disease
Although Parkinson's disease is often associated with motor symptoms such as stiffness, poor balance and trembling, the first symptoms are often sensory and include a reduced sense of touch and smell. In a study on mice, researchers have now been able to identify neural circuits and mechanisms behind this loss of sensory perception. The study may open avenues to methods of earlier diagnosis.
May 18, 2017
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Microsoft's Emma watch could help people with Parkinson's
Sometimes technology is used to really help people's lives.
May 11, 2017
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Mitochondrial lipids as potential targets in early onset Parkinson's disease
A team of researchers has identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' mitochondria, organelles that produce energy. they demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. These results could pave the way to therapies for Parkinson's disease that target lipids.
February 10, 2017
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More brain activity is not always better when it comes to memory, attention
Potential new ways of understanding the cause of cognitive impairments, such as problems with memory and attention, in brain disorders including schizophrenia and Alzheimer's are under the spotlight in a new research review.
June 15, 2017
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MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients
The Medicines Agency of Sweden, MPA, has authorised Herantis Pharma Plc and Renishaw plc's randomised, placebo-controlled Phase 1-2 clinical study, for the investigation of Cerebral Dopamine Neurotrophic Factor (CDNF) and Renishaw's chronic drug delivery system, in Parkinson's patients.
April 4, 2017
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Misc. - N

Neuronal targets to restore movement in Parkinson's disease model
By using optogenetics to control neurons in the basal ganglia, researchers achieve effects that last longer than deep brain stimulation
May 8, 2017
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New brain scan could act as diagnostic tool in Parkinson's
A type of brain scan could act as a diagnostic tool in Parkinson's according to a new study published in the scientific journal Radiology.
December 9, 2016
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New clinical study to test promising Diabetes drug in people with MND
Could a Diabetes drug be used for Motor Neurone Disease?
March 10, 2017
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New drug target for Parkinson's disease found
A new study has found an enzyme that drives neurotoxicity in both Alzheimer's and Parkinson's disease. Blocking the action of this enzyme may prevent these conditions from developing, so the research may have found a new drug target.
July 4, 2017
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New research reveals surprising culprit involved in self-destruction of axons
In many neurodegenerative conditions -- Parkinson's disease, amyotrophic lateral sclerosis (ALS) and peripheral neuropathy among them -- an early defect is the loss of axons, the wiring of the nervous system. When axons are lost, nerve cells can't communicate as they should, and nervous system function is impaired. In peripheral neuropathy in particular, and perhaps other diseases, sick axons trigger a self-destruct program.
March 24, 2017
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New smart gloves to monitor Parkinson's disease patients
Prescribing a medication plan for a patient with Parkinson's disease is a big challenge for doctors, but now a biomedical engineering professor and his students are making great strides in solving that problem with their groundbreaking research.
October 21, 2016
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Non-invasive Deep Brain Stimulation via Interfering High Frequency Signals
Researchers at MIT have developed a new technique to stimulate deep brain regions without the need for invasive implants. Currently, clinicians perform deep brain stimulation by placing electrodes into the brain to stimulate specific areas. As the therapy is so invasive, only patients with serious conditions like Parkinson's disease undergo treatment. The MIT scientists have developed a way to stimulate deep brain regions using electrodes on the scalp, which could potentially revolutionize the way the procedure is performed.
June 2, 2017
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Novel diagnostic approach could pave way for earlier detection of Parkinson's disease
Hebrew University doctoral student Suaad Abd-Elhadi has won a Kaye Innovation Award for her work on a new diagnostic approach that could pave the way for early diagnosis of one of the most common and debilitating neurodegenerative disorders.
July 6, 2017
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Novel mechanism identified to protect the brain from many neurodegenerative conditions
Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer's disease, and Parkinson's disease.
March 8, 2016
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Misc. - O

On the trail of Parkinson's disease
Chemists from Konstanz prove what happens when selective mutations occur to alpha-synuclein protein
March 24, 2017
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Misc. - P

Parkinson's disease may begin in the gut
Around half a million people in the United States are affected by Parkinson's disease, a neurodegenerative disorder. new research published in Neurology reveals that the gut may play a role in the disease and, furthermore, may be where Parkinson's disease begins.
April 27, 2017
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Parkinson's disease protein plays vital 'marshalling' role in healthy brains
Researchers have established how a protein called alpha-synuclein, which is closely associated with Parkinson's Disease, functions in healthy human brains. by showing how the protein works in healthy patients, the study offers important clues about what may be happening when people develop the disease itself.
September 19, 2016
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Parkinson's in a dish: Researchers reproduce brain oscillations
Breakthrough could speed the development of new Parkinson's treatments
May 3, 2017
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Parkinson's is partly an autoimmune disease, study finds
First direct evidence that abnormal protein in Parkinson's disease triggers immune response
June 21, 2017
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Parkinson's risk may be higher with hepatitis virus infection
Individuals infected with hepatitis B or C viruses may have a significantly greater risk of developing Parkinson's disease, new research suggests.
March 30, 2017
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Parkinson's study could pave way for early detection test
A test that can detect Parkinson's disease in the early stages of the illness has moved a step closer.
August 29, 2016
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Parkinson: Weight gain after deep brain stimulation
It was already known that people affected by Parkinson's disease, when subjected to deep brain stimulation, gained weight, but it was less clear why that was so. new research has now shown that the weight gain after implant has a multifactorial origin. the study monitored for the first time a group of patients before and after the intervention, assessing cognitive, psychological and behavioral aspects, providing important elements for preventative purposes.
May 4, 2017
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Parkinson's: 2.5 hours of weekly exercise benefits mobility, quality of life
Exercising for at least 2.5 hours every week may help maintain physical health and quality of life for patients with Parkinson's disease, a new study suggests.
March 24, 2017
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Penn researcher searches for common factor linked to smell loss
Studies have shown that loss of the sense of smell can be among the first warning signs of diseases such as Alzheimer's and Parkinson's. now a researcher at the Perelman School of Medicine at the University of Pennsylvania wants to shift the search for clues about this process back even further, to find out if there is a common factor responsible for the loss of smell that may also serve as an early warning signal for a number of neurodegenerative diseases.
May 10, 2017
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People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, research suggests
A new study is strengthening the therapeutic potential for dietary interventions in Parkinson's disease, suggesting that these patients may benefit from a boost in niacin, which is found in some nuts and meat.
January 10, 2017
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Possible Link Between Some Statins and Parkinson's
But the connection was only seen with certain types of the cholesterol-lowering drugs
June 19, 2017
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Pre-clinical study suggests Parkinson's could start in gut endocrine cells
Protein linked to Parkinson's could spread from gut to nervous system
June 15, 2017
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Precision NanoSystems NanoAssemblr™ Chosen for Horizon 2020 Project to develop Novel RNA Therapeutics
Precision NanoSystems NanoAssemblr™ platform has been selected for the controlled manufacture of nanomedicines as part of the multinational B-SMART (Brain-Specific, Modular and Active RNA Therapeutics) translational research project. this €6 million initiative, funded by the EU Horizon 2020 program, aims to use RNA-based therapeutics to silence the production of disease-causing proteins for a range of neurodegenerative disorders, such as Parkinson's, Alzheimer's and Huntington's.
March 29, 2017
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Predicting cognitive deficits in people with Parkinson's disease
Tool may improve clinical trial design and aid in treatment development
June 21, 2017
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Predicting cognitive deficits in people with Parkinson's disease
NIH-funded tool may improve clinical trial design and aid in treatment development.
June 21, 2017
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Protein associated with Parkinson's travels from brain to gut
New laboratory study provides clues on a particular pathway of 'alpha-synuclein' diffusion
January 5, 2017
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Protein in Parkinson's provokes the immune system
Immune cells treat bits of alpha-synuclein as intruders
June 21, 2017
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Protein linked to Parkinson's travels from gut to brain
Over the course of months, clumps of a protein implicated in Parkinson's disease can travel from the gut into the brains of mice, scientists have found.
November 16, 2016
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Misc. - R

Rare genetic condition may provide insights on Parkinson's and other late-onset diseases
A new article suggests that an enzyme deficiency seen in the lysosomal storage disorder Krabbe's disease may point to new mechanisms underlying certain late-onset neurodegenerative diseases such as Parkinson's disease. Patients with Krabbe's disease lack galactosylceramidase, which is needed to make the protective myelin coating around nerve cells.
September 19, 2016
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Re­search­ers cor­rect Par­kin­son's mo­tor symp­toms in mice
A research group has succeeded in correcting the motor symptoms associated with Parkinson's disease in mice. These results are promising in terms of treatment, since Parkinson's disease is practically always diagnosed only after motor symptoms appear.
December 14, 2016
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Red hair-related gene variant may contribute to link between melanoma and Parkinson's disease
In their paper appearing in the March issue of Annals of Neurology and previously published online, Massachusetts General Hospital (MGH) investigators report that mice carrying the red hair variant of the melanocortin 1 receptor (MC1R) gene have reduced production of the neurotransmitter dopamine in the substantia nigra -- the brain structure in which dopamine-producing neurons are destroyed in Parkinson's disease (PD) -- and are more susceptible to toxins known to damage those neurons.
March 2, 2017
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Regular exercise linked to slower HRQL and mobility decline in PD patients
Exercising 2.5 Hours Per Week Associated with Slower Declines in Parkinson's Disease Patients. According to a new report published in the Journal of Parkinson's Disease
March 23, 2017
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Research shines more light on role of proteins in maintaining synaptic transmission
Synapses are the power junctions that allow living creatures to function. Popularly associated with learning and memory, they play a more fundamental role in our existence by regulating everything from breathing, sleeping and waking and other bodily functions.
August 17, 2016
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Research suggests how malformed proteins linked to Parkinson's could spread from the gut to the brain
Recent research on Parkinson's disease has focused on the gut-brain connection, examining patients' gut bacteria, and even how severing the vagus nerve connecting the stomach and brain might protect some people from the debilitating disease.
June 15, 2017
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Researchers discover how tau disrupts functioning of nerve cells even before forming tangles
Tau proteins are best known as the proteins that are stacked to form neuronal "tangles" in Alzheimer's patients' brains, but they also play a role in many other brain disorders such as Parkinson's and Huntington's disease. In healthy circumstances, tau proteins are connected to the cytoskeleton of nerve cells, where they support the cells' structural stability. In the nerve cells of patients, however, tau is dislodged from the cytoskeleton and ultimately tangles together to form protein accumulations that disrupt the nerve cell's functioning.
May 19, 2017
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Researchers examine how Parkinson's disease alters brain activity over time
Tracking neural changes could help researchers test therapies that slow disease progression.
August 15, 2016
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Researchers identify how amyloid beta linked to Alzheimer's disease could trigger Parkinson's
Alzheimer's and Parkinson's diseases are different neurodegenerative conditions that can sometimes affect the same person, which has led scientists to investigate possible links between the two. now one team, reporting in the journal ACS Chemical Neuroscience, has identified how amyloid beta, the protein fragment strongly associated with Alzheimer's disease, can induce cellular changes that might lead to Parkinson's.
October 12, 2016
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Researchers suggest new theory for how Parkinson's disease develops
The toxic protein behind Parkinson's disease may not spread like an infection from nerve cell to nerve. Instead, say researchers, the protein may simultaneously affect all parts of the nervous system inside and outside of the brain.
March 1, 2017
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Researchers uncover disruption of stress-coping mechanism in Parkinson's disease
Leading-edge research by the team of professor Patrik Verstreken (VIB-KU Leuven) has shown for the first time that a malfunctioning stress-coping mechanism in the brain is at the root of Parkinson's disease. Genetic mutations that cause Parkinson's disease can prevent synapses - the junctions between neurons where electrical signals are transmitted - from coping with the stress of intense brain activity.
October 7, 2016
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Researchers use gene-editing technique to develop new screening tool for Parkinson's disease
A team of researchers at the University of Central Florida is using breakthrough gene-editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system. The technology allows scientists in the lab to "light up" and then monitor a brain protein called alpha-synuclein that has been associated with Parkinson's.
June 5, 2017
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Misc. - S

Safe Delivery of Therapeutic Genes by DNA Barcoding
Researchers used small snippets of DNA as barcodes to develop a new technique for rapidly screening the capability of nanoparticles to selectively deliver therapeutic genes to particular organs of the body. this new technique succeeded in accelerating the development and use of gene therapies for Parkinson™ disease, cancer and heart disease.
February 8, 2017
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Scientific discovery may change treatment of Parkinson
When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. a new study shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.
March 22, 2017
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Scientists developing virtual reality-based early diagnosis system for neurodegenerative disorders
Scientists from Tomsk Polytechnic University and Siberian State Medical University are developing an early diagnosis system for neurodegenerative disorders. the system is intended to such diseases as multiple sclerosis, Parkinson's disease and others. the diagnosis system is based on virtual reality (VR) - a person is immersed in a virtual environment to carry out some functional tests.
September 2, 2016
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Scientists discover how misfolded proteins can damage cells' energy-producing powerhouses
Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbage disposal. Their finding, they say, could help explain part of what goes awry in the progression of such neurodegenerative diseases as Parkinson's and Alzheimer's.
March 3, 2017
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Scientists examine how neural responses change over time in patients with Parkinson's disease
Neuroscientists peered into the brains of patients with Parkinson's disease and two similar conditions to see how their neural responses changed over time. the study, funded by the NIH's Parkinson's Disease Biomarkers Program and published in Neurology, may provide a new tool for testing experimental medications aimed at alleviating symptoms and slowing the rate at which the diseases damage the brain.
August 16, 2016
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Scientists find way to recover protein structure after chemical denaturation
Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation. The method is based on electrostatic interaction between folded, or denatured, proteins and alumina, which unwrap them. The authors highlight the versatility of the method: it works for both specific molecules and, for the first time ever, multiprotein systems - nobody has been able to recover mixtures of enzymes before.
June 9, 2017
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Scientists grow mini human brains
Scientists in Singapore have made a big leap on research on the 'mini-brain'. These advanced mini versions of the human midbrain will help researchers develop treatments and conduct other studies into Parkinson's Disease and ageing-related brain diseases.
July 29, 2016
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Scientists identify new lead in search for Parkinson's cure
A protein that may safeguard neurons from the ravages of Parkinson's disease has been identified by a team of scientists. Parkinson's disease is a progressive disorder that takes years to develop. a better understanding of Prokineticin-2 could turn up a means of slowing development of the disease or lead to new therapies, say the investigators.
October 5, 2016
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Scientists keep a molecule from moving inside nerve cells to prevent cell death
Findings may have implications for Lou Gehrig's, Alzheimer's, Parkinson's and Huntington's diseases
August 03, 2016
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Slowly pulling proteins apart reveals unexpected path to stability
Proteins are long strings of amino acids jumbled together like earphones left inside of a pocket for too long. But while a protein's mess of intertwined knots may look haphazard, their specific folds are extremely important to their biological functions. Misfolded proteins are thought to be the genesis of diseases such as Alzheimer's, Parkinson's, Huntington's and cystic fibrosis, just to name a few.
August 09, 2016
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Spatial structure of amyloid fibrils linked to Parkinson's disease highly dependent on salt concentration
By combining two-dimensional infrared spectroscopy and atomic force microscopy, Amsterdam researchers have established that the spatial structure of amyloid fibrils related to Parkinson's disease is highly dependent on salt concentration during protein aggregation. the results, published recently in Nature's open access journal 'Scientific Reports', can contribute to an explanation of observed differences in fibril-related pathologies.
February 6, 2017
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SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows
When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. a new study conducted in Turku, Finland, shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.
March 22, 2017
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St. Jude Medical Gets FDA Green Light for Infinity Deep Brain Stimulation System for Parkinson's, Essential Tremor
St. Jude Medical is launching in the U.S. its Infinity deep brain stimulation (DBS) system for patients with Parkinson's disease or essential tremor, following FDA approval. the implant comes with a DBS directional lead, the first such lead to receive FDA approval. the lead has segmented contacts, each individually controlled to allow for flexibility in programming the device to achieve optimal results for different patients while minimizing unwanted side effects common to DBS.
October 7, 2016
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Statins may not be used for protection against Parkinson's disease
Statins may not be used for protection against Parkinson's disease
June 14, 2017
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Statins may raise the risk of Parkinson's disease
Thousands of people across the United States are diagnosed with Parkinson's disease every year. New research examines the effect of statins on the risk of developing this neurodegenerative disease.
June 15, 2017
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Study finds link between extended use MAO-B inhibitors and slow clinical decline in PD patients
There has long been interest in whether monoamine oxidase type B (MAO-B) inhibitors slow progression of Parkinson's disease (PD) and improve long-term outcomes.
March 6, 2017
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Study reveals long-term safety of AAV2-neurturin gene therapy in patients with Parkinson's disease
New safety data from a study of patients with advanced Parkinson's disease five years after gene transfer-mediated delivery of the neuroprotective factor neurturin directly to patients' brains reveal no serious adverse events related to the treatment.
July 27, 2016
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Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients
Parkinson disease is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. First described by the English physician James Parkinson two centuries ago, there is yet no cure for PD. Indeed, there is a long list of failed clinical studies based on successful data obtained with exogenous neurotoxin preclinical models
April 12, 2017
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Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature
A Loyola University Chicago study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a similar ability to cause damage when they invade brain cells.
May 23, 2017
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Misc. - T

Targeting Parkinson's-linked protein could neutralize two of the disease's causes
Mouse and human cell studies confirm a common link between proteins and loss of dopamine-making brain cells
February 1, 2017
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This Microsoft wearable is helping Parkinson's patients write again
It's called the Emma Watch, and it vibrates in a specific pattern to stop hand tremors
May 11, 2017
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Thought Processing Concerns Parkinson's Patients
Those with thinking difficulties struggle to follow conversations or recall words
March 18, 2016
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Transcranial stimulation and/or physical therapy improves walking speed in Parkinson's disease
Noninvasive brain stimulation and physical therapy -- alone or in combination -- improve some measures of walking ability in patients with Parkinson's disease (PD), concludes a clinical trial.
June 27, 2017
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Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
Scientists have demonstrated the role of lysosomal vesicles in transporting alpha-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins move from one neuron to the next in lysosomal vesicles which travel along the 'tunneling nanotubes' between cells.
August 22, 2016
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Two existing drugs halt neurodegeneration in mice
Researchers have made a major leap forward in the treatment of Alzheimer's and Parkinson's, after identifying two existing drugs that prevented brain cell death in mouse models of neurodegenerative disease.
April 20, 2017
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Misc. - U

UAB investigators receive BRAIN Initiative award to study new DBS technology for Parkinson's disease
The University of Alabama at Birmingham has received a BRAIN Initiative grant of $7.3 million over five years from the National Institutes of Health to study new technology that could improve outcomes from deep brain stimulation, an increasingly important treatment for Parkinson's disease and other movement disorders.
October 18, 2016
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Misc. - V

Vercise Gevia Deep Brain Stimulation System with Visual Brain Targeting Software Cleared in Europe
Boston Scientific won the CE Mark of approval, allowing for the introduction of the Vercise Gevia Deep Brain Stimulation System in Europe. The Vercise Gevia is indicated for patients with movement disorders such as Parkinson's, dystonia, and essential tremor, helping to calm down involuntary muscle activity that creates serious quality of life issues.
June 8, 2017
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VIB-KU Leuven researchers identify underlying mechanism in early onset Parkinson's disease
A team of researchers led by Patrik Verstreken (VIB-KU Leuven) have identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' mitochondria, organelles that produce energy. they demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. These results could pave the way to therapies for Parkinson's disease that target lipids.
February 10, 2017
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Viral vectors for gene transfer can travel to distant areas in the brain, study shows
Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells. In a study on mice, a team of researchers from Vetmeduni Vienna for the first time investigated how far these viruses spread in the brain and which cells they infect.
June 16, 2017
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Viral vectors for gene transfer travel longer distances in the brain than thought
Gene transfer as a treatment of neurodegenerative diseases
June 16, 2017
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Misc. - W

What is survival among patients with Parkinson, Dementia with lewy bodies?
A new article compares survival rates among patients with synucleinopathies, including Parkinson disease, dementia with Lewy bodies, Parkinson disease dementia and multiple system atrophy with parkinsonism, with individuals in the general population.
May 15, 2017
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Why brain neurons in Parkinson's disease stop benefiting from levodopa
Essential mechanism of long-term memory for L-DOPA-induced-dyskinesia
July 28, 2016
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