The MerchantStoreDirectoryAbout UsAdd-siteLink to Us

 

111 Health - Parkinson's Disease Resources

Misc. - Numbers

'5-D protein fingerprinting' with nanopores could give insights into Alzheimer's, Parkinson's
In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid.
January 17, 2017
Read More


23andMe is finally allowed to tell you if you have the genes for Parkinson's
The Food and Drug Administration finally gave 23andMe a long sought-after green light today to sell to consumers genetic tests and their accompanying health risk reports for up to 10 diseases, including late-onset Alzheimer's and Parkinson's.
April 6, 2017
Read More


23andMe wins FDA approval to give customers health risk info
The gene testing company can now tell US customers who use its home DNA kit whether they have a genetic risk for any of 10 diseases and conditions.
April 6, 2017
Read More


Misc. - A

A Brain Injection of Dna Could Help Control Parkinson's Disease Symptoms
Gene Therapy Would Make Drugs Effective Longer
August 22, 2016
Read More


A cure for Parkinson's? Replacing damaged brain cells shows promise
Researchers may have brought us closer to a cure for Parkinson's disease, after finding a way to replace the brain cells destroyed by the disease.
April 11, 2017
Read More


Altmetric data analysis reveals how Parkinson's disease research affects the world
Scientists have published an analysis of Parkinson's disease research papers with the highest Altmetric Attention Scores. the publication is the first in a series aimed at utilizing Altmetric data to provide a more nuanced understanding of how the announcements of new medical discoveries affect the wide-range of disease-specific stakeholders including researchers, funders, care providers, and patients.
February 13, 2017
Read More


Misc. - B

Big trash pickup for cells
Cells are garbage pickers, carefully selecting the trash they want to keep or discard
August 1, 2016
Read More


Blocking c-Abl enzyme prevents Parkinson's disease progression in mice
Researchers at Johns Hopkins say they have gleaned two important new clues in the fight against Parkinson's disease: that blocking an enzyme called c-Abl prevents the disease in specially bred mice, and that a chemical tag on a second protein may signal the disorder's presence and progression.
June 28, 2016
Read More


Bowel cancer medication could help treat patients with early-onset Parkinson's disease, study suggests
People with certain forms of early-onset Parkinson's disease could potentially benefit from taking a medication used to treat certain forms of cancer, according to new research by University of Leicester scientists and funded by the Medical Research Council.
March 14, 2017
Read More


Breakthrough in production of dopamine neurons for Parkinson's disease
The first transplantation of stem cells in patients with Parkinson's disease is almost within reach, say investigators. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients.
October 28, 2016
Read More


Misc. - C

Cancer drug restores brain dopamine, reduces toxic proteins in Parkinson, dementia
A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson's disease or dementia with Lewy bodies.
July 12, 2016
Read More


Cancer Drug Shows Early Promise for Parkinson's
Medication was generally found safe, and study findings hinted at a benefit
July 12, 2016
Read More


Cell disposal faults could contribute to Parkinson's, study finds
A fault with the natural waste disposal system that helps to keep our brain cell 'batteries' healthy may contribute to neurodegenerative disease, a new study has found.
January 24, 2017
Read More


Could Parkinson's disease start in the gut?
Parkinson's disease may start in the gut and spread to the brain via the vagus nerve, according to a study. the vagus nerve extends from the brainstem to the abdomen and controls unconscious body processes like heart rate and food digestion.
April 26, 2017
Read More


Misc. - D

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases
Rutgers scientists say neurodegenerative diseases like Alzheimer's and Parkinson's may be linked to defective brain cells disposing toxic proteins that make neighboring cells sick.
February 10, 2017
Read More


Dementia not prevented with vitamin E, selenium, study finds
An ample body of research has shown that oxidative stress plays a key role in the development of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. as a result, antioxidant supplements have been proposed as preventive measures against dementia. a new trial, however, tests the effect of vitamin E and selenium on aging men and finds no evidence that they have therapeutic value.
March 19, 2017
Read More


Diabetes drug slows experimental Parkinson's disease progression, human trials to begin next year
A new investigational drug originally developed for type 2 Diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of new research.
December 6, 2016
Read More


Discovery of genetic 'switch' could help to prevent symptoms of Parkinson's disease
A genetic 'switch' has been discovered, which could help to prevent or delay the symptoms of Parkinson's disease, report scientists.
February 17, 2017
Read More


DNA 'barcoding' allows rapid testing of nanoparticles for therapeutic delivery
Using tiny snippets of DNA as 'barcodes,' researchers have developed a new technique for rapidly screening the ability of nanoparticles to selectively deliver therapeutic genes to specific organs of the body. the technique could accelerate the development and use of gene therapies for such killers as heart disease, cancer and Parkinson's disease.
February 7, 2017
Read More


Misc. - E

Enzyme deficiency in Krabbe's disease may point to new mechanisms underlying Parkinson's disease
A new article suggests that an enzyme deficiency seen in the lysosomal storage disorder Krabbe's disease may point to new mechanisms underlying certain late-onset neurodegenerative diseases such as Parkinson's disease.
September 19, 2016
Read More


Exercise May be Real Medicine for Parkinson's
Physical activity helps improve gait and balance, research review finds
December 22, 2016
Read More


Experts discuss new insights into early stages of Parkinson's disease at EAN Congress
"New, neuroprotective or disease-modifying therapies against Parkinson's could be far more effective if administered at an early stage of the disease. Fortunately, we are increasingly able to decipher the mechanisms by which the condition develops thanks to the latest findings and methods, which enables us to identify persons at risk of developing Parkinson's early on," commented Prof Gunther Deuschl of the University Medical Center Schleswig-Holstein in Kiel, and President of the European Academy of Neurology (EAN), at the second EAN Congress in Copenhagen. new insights into the early stages of Parkinson's are among the main topics under discussion at this major medical event.
May 31, 2016
Read More


Misc. - F

Flipping a protein switch to illuminate brain functions
Pacman-shaped receptor's 'bite' sheds light on learning, memory processes
June 27, 2016
Read More


Fountain of youth? Dietary supplement may prevent and reverse severe damage to aging brain, research suggests
A dietary supplement containing a blend of thirty vitamins and minerals--all natural ingredients widely available in health food stores--has shown remarkable anti-aging properties that can prevent and even reverse massive brain cell loss, according to new research. it's a mixture scientists believe could someday slow the progress of catastrophic neurological diseases such as Alzheimer's, ALS and Parkinson's.
June 2, 2016
Read More


Misc. - G

Gamma-ray irradiation improves safety of stem cell transplantation in Parkinson's disease patients
Replacing dopamine-producing cells in the brain represents a promising therapeutic approach in Parkinson's disease, and a new study shows how post-transplantation gamma-ray irradiation can reduce the risk of tumor formation. the study, in which human induced pluripotent stem (iPS) cell-derived neural progenitor cells were grafted into rat brains, is published in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
June 24, 2016
Read More


Gene mutation appears to increase risk of Parkinson's disease in Caucasians
A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. the effect is particularly dramatic for people under age 50.
November 28, 2016
Read More


Gene mutation linked to early onset of Parkinson's disease in caucasians
A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research. the effect is particularly dramatic for young-to-middle-age adults.
November 28, 2016
Read More


Genetic clue to how patients respond to treatment for Parkinson's Disease
Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not.
June 23, 2016
Read More


Get a clue: Biochemist studies fruit fly to understand Parkinson's disease, muscle wasting
By studying the fruit fly, researchers have found a connection between a gene called clueless and genes that cause Parkinson's disease.
June 22, 2016
Read More


Gut may play key role in preventing Parkinson's disease
Your gut may play a pivotal role in preventing the onset of Parkinson's disease. and the reason may be its knack for sleuthing.
October 5, 2016
Read More


Gut microbe mix may spark Parkinson's
In mice, brain inflammation, motor problems linked to intestinal bacteria
December 1, 2016
Read More


Gut microbes promote motor deficits in a mouse model of Parkinson's disease
Gut microbes may play a critical role in the development of Parkinson's-like movement disorders in genetically predisposed mice, researchers report. Antibiotic treatment reduced motor deficits and molecular hallmarks of Parkinson's disease in a mouse model, whereas transplantation of gut microbes from patients with Parkinson's disease exacerbated symptoms in these mice. the findings could lead to new treatment strategies for the second most common neurodegenerative disease in the United States.
December 1, 2016
Read More


Misc. - H

Hand-grip test can indicate decline in physical function of Parkinson's patients
A basic hand-grip test has proven to be a reliable tool to monitor the decline of patients with Parkinson's diseases, say investigators.
February 1, 2017
Read More


Hand-grip test proves to be easy, reliable way to examine muscle strength decline in PD patients
UBC researchers Jenn Jakobi and Gareth Jones, both Health and Exercise Sciences professors at UBC's Okanagan campus, recently completed a study that examined the methods used to monitor the progressive advancement of Parkinson's disease (PD)--a degenerative disease that affects the central nervous system.
February 1, 2017
Read More


How this small wearable could help doctors spot Parkinson's earlier
The low-cost ENTy wearable, which has been tested on over 500 patients so far, seems to have a future helping diagnose people with balance issues.
September 15, 2016
Read More


Misc. - I

Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease
Researchers at Johns Hopkins report they have identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal's brain – and a way to block that protein's action. Their study in mice and cultured cells suggests that an immunotherapy already in clinical trials as a cancer therapy should also be tested as a way to slow the progress of Parkinson's disease, the researchers say.
September 29, 2016
Read More


Impaired decision-making may contribute to motor symptoms in Parkinson's disease
Findings could lead to strategies for earlier detection
June 16, 2016
Read More


IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets
Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure.
August 16, 2016
Read More


Is It Parkinson's Disease? Blood Test Might Tell
But new technique needs more study, researchers say
February 8, 2017
Read More


Misc. - L

Link between microbiome in the gut, Parkinson's discovered
Parkinson's disease, and medications to treat Parkinson's, have distinct effects on the composition of the trillions of bacteria that make up the gut microbiome, new research shows.
March 2, 2017
Read More


Link found between traumatic brain injury and Parkinson's, but not Alzheimer's
Traumatic brain injury with a loss of consciousness may be associated with later development of Parkinson's disease but not Alzheimer's disease or incident dementia, new research indicates.
July 11, 2016
Read More


Lund study shows transplanted nerve cells can survive for many years in diseased human brain
In the late 1980s and over the 1990s, researchers at Lund University in Sweden pioneered the transplantation of new nerve cells into the brains of patients with Parkinson's disease. the outcomes proved for the first time that transplanted nerve cells can survive and function in the diseased human brain. some patients showed marked improvement after the transplantation while others showed moderate or no relief of symptoms. a small number of patients suffered unwanted side-effects in the form of involuntary movements.
May 4, 2016
Read More


Misc. - M

Metabolite of multiple sclerosis drug could be safe, effective therapy for Parkinson's disease
The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say.
June 8, 2016
Read More


Mitochondrial lipids as potential targets in early onset Parkinson's disease
A team of researchers has identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' mitochondria, organelles that produce energy. they demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. These results could pave the way to therapies for Parkinson's disease that target lipids.
February 10, 2017
Read More


MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients
The Medicines Agency of Sweden, MPA, has authorised Herantis Pharma Plc and Renishaw plc's randomised, placebo-controlled Phase 1-2 clinical study, for the investigation of Cerebral Dopamine Neurotrophic Factor (CDNF) and Renishaw's chronic drug delivery system, in Parkinson's patients.
April 4, 2017
Read More


Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease
A new study has shown that myricitrin, a flavinoid with antioxidant and anti-inflammatory activity that is present inedible plants and fruit, can protect mouse brains from the loss of dopamine-producing neurons caused by neurotoxicity. the reported effects of myricitrin suggest that it could have a role in preventing the neuronal degeneration that occurs in Parkinson's disease, as described in an article published in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
June 7, 2016
Read More


Misc. - N

Natural molecule could improve Parkinson's
A natural molecule shows benefit in a preliminary clinical trial for Parkinson's Disease, report scientists. Current treatments for Parkinson's disease are generally limited to temporarily replacing dopamine in the brain as well as some medications designed to slow the progression of the disease process.
June 16, 2016
Read More


NeuroDerm starts patient enrollment in long-term safety study of ND0612 for treatment of Parkinson's disease
NeuroDerm Ltd., a clinical stage pharmaceutical company developing drugs for central nervous system (CNS) disorders, today announced the start of patient enrollment in a long-term safety study (trial 012) of the company's continuously administered subcutaneous levodopa/carbidopa (LD/CD) formulation used in both ND0612H and ND0612L.
May 13, 2016
Read More


New brain scan could act as diagnostic tool in Parkinson's
A type of brain scan could act as a diagnostic tool in Parkinson's according to a new study published in the scientific journal Radiology.
December 9, 2016
Read More


New clinical study to test promising Diabetes drug in people with MND
Could a Diabetes drug be used for Motor Neurone Disease?
March 10, 2017
Read More


New findings challenge current view on origins of Parkinson's disease
Researchers investigate 'mutant flies'
June 23, 2016
Read More


New gene shown to cause Parkinson's disease
Third gene definitely linked to disease in patients from North America, Asia
June 5, 2016
Read More


New research reveals surprising culprit involved in self-destruction of axons
In many neurodegenerative conditions -- Parkinson's disease, amyotrophic lateral sclerosis (ALS) and peripheral neuropathy among them -- an early defect is the loss of axons, the wiring of the nervous system. When axons are lost, nerve cells can't communicate as they should, and nervous system function is impaired. In peripheral neuropathy in particular, and perhaps other diseases, sick axons trigger a self-destruct program.
March 24, 2017
Read More


New smart gloves to monitor Parkinson's disease patients
Prescribing a medication plan for a patient with Parkinson's disease is a big challenge for doctors, but now a biomedical engineering professor and his students are making great strides in solving that problem with their groundbreaking research.
October 21, 2016
Read More


New UCLA study reveals strategy to fight against pesticide-associated Parkinson's disease
Exposure to a group of common pesticides, called dithiocarbamates, has long been associated with an increased risk of Parkinson's disease, although the mechanism by which the compounds exert their toxicity on the brain has not been completely understood. a new UCLA study sheds light on the toxicity of the compounds while also suggesting a strategy that may help protect against the disease.
June 15, 2016
Read More


Novel mechanism identified to protect the brain from many neurodegenerative conditions
Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer's disease, and Parkinson's disease.
March 8, 2016
Read More


Misc. - O

On the trail of Parkinson's disease
Chemists from Konstanz prove what happens when selective mutations occur to alpha-synuclein protein
March 24, 2017
Read More


Misc. - P

Parkinson's Disease biomarker found in patient urine samples
Stored samples of urine and cerebral-spinal fluid from patients with Parkinson's disease hold a brand-new type of biomarker -- a phosphorylated protein that correlates with the presence and severity of Parkinson's disease -- new research indicates
July 5, 2016
Read More


Parkinson's disease may begin in the gut
Around half a million people in the United States are affected by Parkinson's disease, a neurodegenerative disorder. new research published in Neurology reveals that the gut may play a role in the disease and, furthermore, may be where Parkinson's disease begins.
April 27, 2017
Read More


Parkinson's disease pathogenesis reduced in rat model by a cell-signaling inhibitor drug
Researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 -- one of the JAK/STAT pathway inhibitors generally known as Jakinibs -- lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.
May 4, 2016
Read More


Parkinson's disease protein plays vital 'marshalling' role in healthy brains
Researchers have established how a protein called alpha-synuclein, which is closely associated with Parkinson's Disease, functions in healthy human brains. by showing how the protein works in healthy patients, the study offers important clues about what may be happening when people develop the disease itself.
September 19, 2016
Read More


Parkinson's risk may be higher with hepatitis virus infection
Individuals infected with hepatitis B or C viruses may have a significantly greater risk of developing Parkinson's disease, new research suggests.
March 30, 2017
Read More


Parkinson's study could pave way for early detection test
A test that can detect Parkinson's disease in the early stages of the illness has moved a step closer.
August 29, 2016
Read More


Parkinson's: 2.5 hours of weekly exercise benefits mobility, quality of life
Exercising for at least 2.5 hours every week may help maintain physical health and quality of life for patients with Parkinson's disease, a new study suggests.
March 24, 2017
Read More


People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, research suggests
A new study is strengthening the therapeutic potential for dietary interventions in Parkinson's disease, suggesting that these patients may benefit from a boost in niacin, which is found in some nuts and meat.
January 10, 2017
Read More


Precision NanoSystems NanoAssemblr™ Chosen for Horizon 2020 Project to develop Novel RNA Therapeutics
Precision NanoSystems NanoAssemblr™ platform has been selected for the controlled manufacture of nanomedicines as part of the multinational B-SMART (Brain-Specific, Modular and Active RNA Therapeutics) translational research project. this €6 million initiative, funded by the EU Horizon 2020 program, aims to use RNA-based therapeutics to silence the production of disease-causing proteins for a range of neurodegenerative disorders, such as Parkinson's, Alzheimer's and Huntington's.
March 29, 2017
Read More


Protein associated with Parkinson's travels from brain to gut
New laboratory study provides clues on a particular pathway of 'alpha-synuclein' diffusion
January 5, 2017
Read More


Protein linked to Parkinson's travels from gut to brain
Over the course of months, clumps of a protein implicated in Parkinson's disease can travel from the gut into the brains of mice, scientists have found.
November 16, 2016
Read More


Misc. - R

Rare genetic condition may provide insights on Parkinson's and other late-onset diseases
A new article suggests that an enzyme deficiency seen in the lysosomal storage disorder Krabbe's disease may point to new mechanisms underlying certain late-onset neurodegenerative diseases such as Parkinson's disease. Patients with Krabbe's disease lack galactosylceramidase, which is needed to make the protective myelin coating around nerve cells.
September 19, 2016
Read More


Re­search­ers cor­rect Par­kin­son's mo­tor symp­toms in mice
A research group has succeeded in correcting the motor symptoms associated with Parkinson's disease in mice. These results are promising in terms of treatment, since Parkinson's disease is practically always diagnosed only after motor symptoms appear.
December 14, 2016
Read More


Red hair-related gene variant may contribute to link between melanoma and Parkinson's disease
In their paper appearing in the March issue of Annals of Neurology and previously published online, Massachusetts General Hospital (MGH) investigators report that mice carrying the red hair variant of the melanocortin 1 receptor (MC1R) gene have reduced production of the neurotransmitter dopamine in the substantia nigra -- the brain structure in which dopamine-producing neurons are destroyed in Parkinson's disease (PD) -- and are more susceptible to toxins known to damage those neurons.
March 2, 2017
Read More


Regular exercise linked to slower HRQL and mobility decline in PD patients
Exercising 2.5 Hours Per Week Associated with Slower Declines in Parkinson's Disease Patients. According to a new report published in the Journal of Parkinson's Disease
March 23, 2017
Read More


Research shines more light on role of proteins in maintaining synaptic transmission
Synapses are the power junctions that allow living creatures to function. Popularly associated with learning and memory, they play a more fundamental role in our existence by regulating everything from breathing, sleeping and waking and other bodily functions.
August 17, 2016
Read More


Researchers examine how Parkinson's disease alters brain activity over time
Tracking neural changes could help researchers test therapies that slow disease progression.
August 15, 2016
Read More


Researchers find potential breakthrough in binge-eating disorder treatment
A treatment used for depression, Parkinson's disease and autism shows promise to alleviate obesity in binge-eating disorder patients. tDCS is a type of neuromodulator that delivers constant, low-current electricity to a targeted portion of the brain.
May 10, 2016
Read More


Researchers have engineered monkeys with Parkinson's disease
It's a controversial use of genetic engineering that could lead to major breakthroughs.
June 15, 2016
Read More


Researchers identify how amyloid beta linked to Alzheimer's disease could trigger Parkinson's
Alzheimer's and Parkinson's diseases are different neurodegenerative conditions that can sometimes affect the same person, which has led scientists to investigate possible links between the two. now one team, reporting in the journal ACS Chemical Neuroscience, has identified how amyloid beta, the protein fragment strongly associated with Alzheimer's disease, can induce cellular changes that might lead to Parkinson's.
October 12, 2016
Read More


Researchers open new path of discovery in Parkinson's disease
Neuron cell death may be caused by overactive immune system
June 27, 2016
Read More


Researchers suggest new theory for how Parkinson's disease develops
The toxic protein behind Parkinson's disease may not spread like an infection from nerve cell to nerve. Instead, say researchers, the protein may simultaneously affect all parts of the nervous system inside and outside of the brain.
March 1, 2017
Read More


Researchers uncover disruption of stress-coping mechanism in Parkinson's disease
Leading-edge research by the team of professor Patrik Verstreken (VIB-KU Leuven) has shown for the first time that a malfunctioning stress-coping mechanism in the brain is at the root of Parkinson's disease. Genetic mutations that cause Parkinson's disease can prevent synapses - the junctions between neurons where electrical signals are transmitted - from coping with the stress of intense brain activity.
October 7, 2016
Read More


Misc. - S

Safe Delivery of Therapeutic Genes by DNA Barcoding
Researchers used small snippets of DNA as barcodes to develop a new technique for rapidly screening the capability of nanoparticles to selectively deliver therapeutic genes to particular organs of the body. this new technique succeeded in accelerating the development and use of gene therapies for Parkinson™ disease, cancer and heart disease.
February 8, 2017
Read More


Scientific discovery may change treatment of Parkinson
When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. a new study shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.
March 22, 2017
Read More


Scientists developing virtual reality-based early diagnosis system for neurodegenerative disorders
Scientists from Tomsk Polytechnic University and Siberian State Medical University are developing an early diagnosis system for neurodegenerative disorders. the system is intended to such diseases as multiple sclerosis, Parkinson's disease and others. the diagnosis system is based on virtual reality (VR) - a person is immersed in a virtual environment to carry out some functional tests.
September 2, 2016
Read More


Scientists discover how misfolded proteins can damage cells' energy-producing powerhouses
Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbage disposal. Their finding, they say, could help explain part of what goes awry in the progression of such neurodegenerative diseases as Parkinson's and Alzheimer's.
March 3, 2017
Read More


Scientists discover protective strategy against pesticide-linked Parkinson's disease
A new study sheds light on the toxicity of the pesticides related to Parkinson's while also suggesting a strategy that may help protect against the disease.
June 15, 2016
Read More


Scientists examine how neural responses change over time in patients with Parkinson's disease
Neuroscientists peered into the brains of patients with Parkinson's disease and two similar conditions to see how their neural responses changed over time. the study, funded by the NIH's Parkinson's Disease Biomarkers Program and published in Neurology, may provide a new tool for testing experimental medications aimed at alleviating symptoms and slowing the rate at which the diseases damage the brain.
August 16, 2016
Read More


Scientists grow mini human brains
Scientists in Singapore have made a big leap on research on the 'mini-brain'. These advanced mini versions of the human midbrain will help researchers develop treatments and conduct other studies into Parkinson's Disease and ageing-related brain diseases.
July 29, 2016
Read More


Scientists Have Created Monkeys with Parkinson's Disease
Six months after researchers in China bioengineered monkeys to have autism, a Japanese team of scientists has used the same technology to create monkeys with Parkinson's. it's a scientific first, and it could lead to effective treatments–but do the ends justify the means?
June 15, 2016
Read More


Scientists identify new lead in search for Parkinson's cure
A protein that may safeguard neurons from the ravages of Parkinson's disease has been identified by a team of scientists. Parkinson's disease is a progressive disorder that takes years to develop. a better understanding of Prokineticin-2 could turn up a means of slowing development of the disease or lead to new therapies, say the investigators.
October 5, 2016
Read More


Scientists keep a molecule from moving inside nerve cells to prevent cell death
Findings may have implications for Lou Gehrig's, Alzheimer's, Parkinson's and Huntington's diseases
August 03, 2016
Read More


Shedding new light on protein aggregates and the diseases they cause
Researchers have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. Proteins regulate all of the processes that keep cells alive, but when misfolded they can clump into large aggregations, a phenomenon associated with diseases including Alzheimer's, Huntington's and Parkinson's.
July 13, 2016
Read More


Slowly pulling proteins apart reveals unexpected path to stability
Proteins are long strings of amino acids jumbled together like earphones left inside of a pocket for too long. But while a protein's mess of intertwined knots may look haphazard, their specific folds are extremely important to their biological functions. Misfolded proteins are thought to be the genesis of diseases such as Alzheimer's, Parkinson's, Huntington's and cystic fibrosis, just to name a few.
August 09, 2016
Read More


Smell tests, biomarkers and colon biopsies: new approaches to early identification of Parkinson's disease
Early diagnosis and starting treatment as early as possible are decisive factors in achieving improved quality of life for Parkinson's sufferers.
May 30, 2016
Read More


Spatial structure of amyloid fibrils linked to Parkinson's disease highly dependent on salt concentration
By combining two-dimensional infrared spectroscopy and atomic force microscopy, Amsterdam researchers have established that the spatial structure of amyloid fibrils related to Parkinson's disease is highly dependent on salt concentration during protein aggregation. the results, published recently in Nature's open access journal 'Scientific Reports', can contribute to an explanation of observed differences in fibril-related pathologies.
February 6, 2017
Read More


SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows
When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. a new study conducted in Turku, Finland, shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.
March 22, 2017
Read More


St. Jude Medical Gets FDA Green Light for Infinity Deep Brain Stimulation System for Parkinson's, Essential Tremor
St. Jude Medical is launching in the U.S. its Infinity deep brain stimulation (DBS) system for patients with Parkinson's disease or essential tremor, following FDA approval. the implant comes with a DBS directional lead, the first such lead to receive FDA approval. the lead has segmented contacts, each individually controlled to allow for flexibility in programming the device to achieve optimal results for different patients while minimizing unwanted side effects common to DBS.
October 7, 2016
Read More


Study finds link between extended use MAO-B inhibitors and slow clinical decline in PD patients
There has long been interest in whether monoamine oxidase type B (MAO-B) inhibitors slow progression of Parkinson's disease (PD) and improve long-term outcomes.
March 6, 2017
Read More


Study finds no substantial link between gadolinium exposure and parkinsonism
In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.
July 6, 2016
Read More


Study Links Severe Head Injury to Parkinson's Risk
Researchers only found an association, could not explain why connection might exist
July 11, 2016
Read More


Study reveals long-term safety of AAV2-neurturin gene therapy in patients with Parkinson's disease
New safety data from a study of patients with advanced Parkinson's disease five years after gene transfer-mediated delivery of the neuroprotective factor neurturin directly to patients' brains reveal no serious adverse events related to the treatment.
July 27, 2016
Read More


Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients
Parkinson disease is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. First described by the English physician James Parkinson two centuries ago, there is yet no cure for PD. Indeed, there is a long list of failed clinical studies based on successful data obtained with exogenous neurotoxin preclinical models
April 12, 2017
Read More


Misc. - T

Targeting Parkinson's-linked protein could neutralize two of the disease's causes
Mouse and human cell studies confirm a common link between proteins and loss of dopamine-making brain cells
February 1, 2017
Read More


Thought Processing Concerns Parkinson's Patients
Those with thinking difficulties struggle to follow conversations or recall words
March 18, 2016
Read More


Transplanted nerve cells survive a quarter of a century in a Parkinson's disease patient
In the late 1980s and over the 1990s, researchers pioneered the transplantation of new nerve cells into the brains of patients with Parkinson's disease. the outcomes proved for the first time that transplanted nerve cells can survive and function in the diseased human brain. some patients showed marked improvement after the transplantation while others showed moderate or no relief of symptoms. a small number of patients suffered unwanted side-effects in the form of involuntary movements.
May 3, 2016
Read More


Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
Scientists have demonstrated the role of lysosomal vesicles in transporting alpha-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins move from one neuron to the next in lysosomal vesicles which travel along the 'tunneling nanotubes' between cells.
August 22, 2016
Read More


Two existing drugs halt neurodegeneration in mice
Researchers have made a major leap forward in the treatment of Alzheimer's and Parkinson's, after identifying two existing drugs that prevented brain cell death in mouse models of neurodegenerative disease.
April 20, 2017
Read More


Two gene variants provide clue to why some patients with PD respond well to rasagiline drug
Researchers have identified a gene variant which explains why some patients with Parkinson's Disease respond well to drug treatment and other do not.
June 23, 2016
Read More


Misc. - U

UAB investigators receive BRAIN Initiative award to study new DBS technology for Parkinson's disease
The University of Alabama at Birmingham has received a BRAIN Initiative grant of $7.3 million over five years from the National Institutes of Health to study new technology that could improve outcomes from deep brain stimulation, an increasingly important treatment for Parkinson's disease and other movement disorders.
October 18, 2016
Read More


Misc. - V

VIB-KU Leuven researchers identify underlying mechanism in early onset Parkinson's disease
A team of researchers led by Patrik Verstreken (VIB-KU Leuven) have identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' mitochondria, organelles that produce energy. they demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. These results could pave the way to therapies for Parkinson's disease that target lipids.
February 10, 2017
Read More


Misc. - W

Why brain neurons in Parkinson's disease stop benefiting from levodopa
Essential mechanism of long-term memory for L-DOPA-induced-dyskinesia
July 28, 2016
Read More


Wolff-Parkinson-White patients continue to have atrial fibrillation risk even after catheter ablation, study finds
Patients with Wolff-Parkinson-White syndrome who receive catheter ablation to cure their abnormal heart rhythms are just as likely as non-ablated patients to develop atrial fibrillation no matter what age they receive ablation, according to a new study.
May 6, 2016
Read More


The MerchantStore © 1997 - 2017