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211 Health - Stem Cell Resources

Misc. - Numbers

3D bone-like tissues made from pluripotent stem cells
Researchers at the University of Tokyo have developed a cell culture method that generates three-dimensional bone-like tissues from mouse pluripotent stem cells--cells which can differentiate into various tissue types and have infinite growth potential--using only small molecules, in given conditions, as inducers.
June 28, 2017
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Misc. - A

A nanofiber matrix for healing
A new nanofiber-on-microfiber matrix could help produce more and better quality stem cells for disease treatment and regenerative therapies.
February 14, 2017
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A Semi-Automated Benchtop System to Produce Genetically Modified Stem Cells: Interview with Professor Jennifer Adair
Scientists at the Fred Hutchinson Cancer Research Center and the University of Washington have developed a semi-automated benchtop system to produce clinical-grade genetically modified haematopoietic stem cells (HSCs).
November 11, 2016
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A signal of safe therapy
Stem cells have paved the way for a new era in regenerative medicine, but their use is fraught with risk. Now, A*STAR scientists have developed an antibody that could make stem cell therapy safer.
June 15, 2017
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Ability of stem cells expanded to regrow any tissue type
A new technique, which allows scientists to generate both embryonic and non-embryonic tissues from cultured stem cells, is a step toward growing donor organs and replacement tissues to combat aging and diseases.
April 6, 2017
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Aging process increases DNA mutations in important type of stem cell
Researchers say results should be considered when designing iPSC therapies
December 12, 2016
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Alerting stem cells to hurry up and heal
Accelerated healing isn't just for superheroes. a new study suggests a way that mere mortals can potentially speed their recovery from a wide variety of injuries.
April 18, 2017
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Altering stem cell perception of tissue stiffness may help treat musculoskeletal disorders
A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment. with further development, this biomaterial could be used to control when immature stem cells differentiate into more specialized cells for regenerative and tissue-engineering-based therapies.
August 25, 2016
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Approaching a decades-old goal: Making blood stem cells from patients' own cells
New technique raises possibility of making all types of blood cells to treat disease
May 17, 2017
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Are engineered organs finally becoming reality in medicine?
The concept behind tissue engineering is simple: grow the patient's stem cells in the laboratory, add them to a scaffold material, and you have a laboratory-grown organ. But few patients have benefited from this technology so far. Could change be on the horizon?
July 6, 2017
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Artificial Stem Cells Promote Tissue Healing Minus Side Effects
A collaboration between researchers at North Carolina State University, the University of North Carolina at Chapel Hill, and First Affiliated Hospital of Zhengzhou University have apparently created a synthetic mimic of cardiac stem cells. These may end up being used instead of natural stem cells while reducing or eliminating side effects that may arise from stem cell therapy.
January 12, 2017
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Assigning barcode to stem cells makes it possible to monitor large blood cell populations
By assigning a barcode to stem cells, researchers at Lund University in Sweden have made it possible to monitor large blood cell populations as well as individual blood cells, and study the changes over time. Among other things, they discovered that stem cells go through different stages where their ability to restore immune cells varies. the new findings provide important information for the research and treatment of leukaemia and autoimmune diseases.
August 24, 2016
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Misc. - B

"Brains in a dish' move out of science fiction and into the lab
Growing brain-like tissues in cell culture lets scientists study neurodevelopment.
May 4, 2017
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Barcodes show the blood family tree
By assigning a barcode to stem cells, researchers have made it possible to monitor large blood cell populations as well as individual blood cells, and study the changes over time. Among other things, they discovered that stem cells go through different stages where their ability to restore immune cells varies.
August 24, 2016
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Bismuth-Enhanced Nanotubes Improved for Use as X-Ray Contrast Agent
Researchers at Rice University have synthesized a new and significantly enhanced generation of contrast agents for tagging and real-time tracking of the body's stem cells.
February 1, 2017
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Breakthrough technique harvests stem cells from urine to study Down syndrome
One of the biggest challenges in studying Down syndrome is finding the right research model. Animals and established cell lines are limited in their ability to mimic human disease, and results don't always translate to patient populations. Stem cells hold enormous potential as research tools that can be collected directly from patients and grown into innumerable cell types. But harvesting stem cells can be tricky and invasive -- a tough sell to institutional review boards when dealing with children or patients with intellectual disability.
March 28, 2017
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Bright red fluorescent protein created
After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. this is good news for researchers, including cancer and stem cell researchers, who use fluorescent proteins to track essential cellular processes.
November 23, 2016
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Misc. - C

Cancer stem cells in 'robbers cave' may explain poor prognosis for obese patients
A new study offers a compelling hypothesis explaining poor prognosis for obese cancer patients: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy.
July 20, 2016
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Carbon Nanotubes as X-ray Contrast Agents to Track Stem Cells Inside Body
Researchers at Rice University have come up with a better X-ray contrast agent, which may allow for very precise tracking of cells, biomolecules, and other particles within the body. In particular, the researchers believe that seeing whether stem cells are moving towards and healing diseased tissue will be one of the first important applications for this technology.
February 6, 2017
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Cardiac stem cells from heart disease patients may be harmful
Researchers discover molecular pathway involved in toxic interaction between host cells and immune system
June 15, 2017
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Cell-tracking nanomaterial agents get a boost
Rice University researchers have synthesized a new and greatly improved generation of contrast agents for tagging and real-time tracking of stem cells in the body.
January 30, 2017
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Chip captures individual cells in minuscule gels
Researchers at the University of Twente's MIRA research institute have developed a chip that can capture and hold individual cells in the exact centre of a minuscule hydrogel droplet. Their novel method keeps cells alive for multiple weeks, which makes it easier to study them. This makes it possible to, for example, test the action of new drugs and improve stem cell therapies with unparalleled control.
June 12, 2017
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Cigarette damage to unborn children revealed in stem cell study
Chemicals found in cigarette smoke have been shown to damage foetal liver cells. Researchers have now developed a novel way to study the effects of maternal smoking on liver tissue using embryonic stem cells.
May 30, 2017
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Clinical study tests adult stem cell therapy for infants with congenital HLHS
In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine and the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome.
December 21, 2016
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Clear view on stem cell development
Image correction software simplifies quantification of stem cells
June 21, 2017
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Clear view on stem cell development
When stem cells develop into specialized cells, this happens in multiple steps. But which regulatory proteins are active during the decisive branching on the development path? Using so-called time-lapse microscopy, researchers can observe individual cells at very high time resolutions and, using fluorescent labelling, they can recognize precisely which of these proteins appear when in the cell.
June 23, 2017
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Misc. - D

Defining immortality of stem cells to identify novel anti-aging mechanisms
With age, somatic cells such as neurons lose their ability to maintain the quality of their protein content. Pluripotent stem cells, on the contrary, do not age and have increased mechanism to maintain the integrity of their proteins.
November 28, 2016
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Discovery of a new regulatory protein provides new tool for stem cell engineering
Bioengineers have discovered a protein that regulates the switch of embryonic stem cells from the least developed 'na´ve' state to the more developed 'primed' state. this discovery sheds light on stem cell development at a molecular level.
March 28, 2017
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Discovery of a novel Wnt inhibitor with potential to eradicate colorectal cancer stem cells, report researchers
A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. the inhibitor may provide a new therapy option for patients with drug-refractory colorectal cancer.
August 26, 2016
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Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism
University of Oregon researchers using Drosophila have identified a steroid hormone that triggers a vital transition in early brain development in which neural stem cells properly change gears to produce different kinds of neurons.
May 15, 2017
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Discovery offers new hope to repair spinal cord injuries
Scientists produce a type of stem cell-derived neuron that could potentially help restore movement
April 24, 2017
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Distant brain regions selectively recruit stem cells
Stem cells persist in the adult mammalian brain and generate new neurons throughout life. A research group reports that long-distance brain connections can target discrete pools of stem cells in their niche and stimulate them to divide and produce specific subtypes of olfactory bulb neurons. This allows the 'on-demand' generation of particular types of neurons in the adult brain.
June 16, 2017
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Misc. - E

Early treatment with stem cells can safely help recovery in stroke patients, study shows
A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first three months, researchers report.
March 19, 2017
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Embryonic gene Nanog reverses aging in adult stem cells
The discovery may lead to treatments for atherosclerosis, osteoporosis, Alzheimer's and other age-related disorders
July 25, 2016
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Engineering human stem cells to model the kidney's filtration barrier on a chip
The kidney - made up of about a million tiny units that work to filter blood, constantly rids the body of undesired waste products to form urine while holding back blood cells and valuable proteins, and controls the body's fluid content. Key to each of these units is a structure known the 'glomerulus', in which so-called podocyte cells wrap themselves tightly around a tuft of capillaries separated from them only by a thin membrane composed of extracellular matrix, and leaving slits between them to build an actual filtration barrier.
May 10, 2017
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Misc. - F

First 'haploid' human stem cells could change the face of medical research
Stem cell research holds huge potential for medicine and human health. In particular, human embryonic stem cells (ESCs), with their ability to turn into any cell in the human body, are essential to the future prevention and treatment of disease.
June 28, 2017
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From skin to brain: Stem cells without genetic modification
A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.
March 16, 2017
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Misc. - G

Genes need to be screened for stem cell transplants
Findings underscore need for screening methods to improve safety of promising experimental treatments
April 26, 2017
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Genetic factors control regenerative properties of blood-forming stem cells
Two studies define how key genetic factors affect blood-forming stem cells by either accelerating or hindering the cells' regenerative properties. the findings could one day lead to improved treatments for people undergoing common therapies for cancer such as chemotherapy and radiation, say researchers.
December 5, 2016
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Graft-versus-host disease successfully prevented
Regimen may stop common side effect of stem cell transplants for hematologic cancer patients, report suggests
April 18, 2017
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Grape-based compounds could pave way for new treatments to prevent colon cancer
Compounds from grapes may kill colon cancer stem cells both in a petri dish and in mice, according to a team of researchers.
June 19, 2017
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Grape-based compounds kill colon cancer stem cells in mice
Compounds from grapes may kill colon cancer stem cells both in a petri dish and in mice, according to a team of researchers.
June 19, 2017
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Misc. - H

Healthy fat stem cells can protect against obesity-associated type 2 diabetes
Obesity is responsible for the deaths of over three million people a year worldwide due to its associated diseases such as diabetes, cancer and cardiovascular disease. However, a subset of obese individuals seems to be protected from such diseases.
September 16, 2016
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Heart failure: Stem cell therapy may worsen heart damage
Stem cell therapy is often a "last resort" treatment for patients with end-stage heart failure. A new study, however, finds that the treatment could be more harmful than helpful if cardiac stem cells are involved.
June 16, 2017
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How neural stem cells can become blood vessels
This finding could have a great impact on the study of pediatric tumors, as it could already constitute one of the factors that produces their growth
May 18, 2017
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HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis
Researchers at Hospital for Special Surgery have launched a study to determine if a treatment using stem cells could help people with painful knee arthritis. to evaluate safety and efficacy, investigators are currently recruiting patients with moderate osteoarthritis, which comes from wear and tear on a joint.
July 21, 2016
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Human heart tissue grown from stem cells improves drug testing
Researchers at the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR have engineered a three-dimensional heart tissue from human stem cells to test the safety and efficacy of new drugs on the heart (Biofabrication, "Engineering a functional three-dimensional human cardiac tissue model for drug toxicity screening").
June 8, 2017
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Human stem cells treat spinal cord injury side effects in mice
People with spinal cord injuries suffer from many complications in addition to paralysis and numbness. some of these problems are caused by a lack of the neurotransmitter GABA in the injured spinal cord. now research in mice is showing that human embryonic stem cells differentiated into medial ganglionic eminence (MGE)-like cells, which produce GABA, may help alleviate two of the most severe side effects -- chronic neuropathic pain and bladder dysfunction.
October 3, 2016
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Human-pig hybrid grown in lab. (Actually happened)
Scientists at the Salk Institute inject human stem cells into a pig embryo in research to create organs for transplantation.
January 26, 2017
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Misc. - I

Identical twins, not-so-identical stem cells
A new twin study sheds light on what causes reprogrammed stem cells to have different epigenetic patterns. the findings are being used for research and therapeutics, say the researchers.
April 19, 2017
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Innovative Process for Differentiating Stem Cells into Schwann-Like Cells
Scientists searching for the means to regenerate nerves might find it difficult to acquire the important tools needed for research. One such example is Schwann cells that form sheaths enclosing axons, which are tail-like portions of nerve cells that convey electrical impulses. In addition to promoting regeneration of the axons, the Schwann cells discharge substances, boosting the health of nerve cells.
April 11, 2017
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In some genetic cases of microcephaly, stem cells fail to launch
Uncovering how genetic defects cause microcephaly may help Zika researchers
August 24, 2016
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Misc. - K

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds
A key gene enables the repair of injured muscle throughout life. this is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in Cell Reports.
July 21, 2016
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Misc. - L

Lab-grown human colons change study of GI disease
Stem cell derived organoids fill gap in modeling common ailments
June 22, 2017
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LCSB researchers identify how the body influences differentiation of progenitor cells
Stem cells are unspecialised cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will differentiate, for example, into a blood, liver or nerve cell.
March 15, 2017
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Let there be tissue
Nothing beats nature. the diverse and wonderful varieties of cells and tissues that comprise the human body are evidence of that.
May 15, 2017
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Let there be tissue: More precise, controlled method of engineering tissues from stem cells
Near-infrared light proves an effective and precise tool for engineering tissues from stem cells, report scientists.
May 15, 2017
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Long-distance brain connections can target, stimulate discrete pools of stem cells
Stem cells persist in the adult mammalian brain and generate new neurons throughout life. A research group at the Biozentrum of the University of Basel reports in the current issue of "Science" that long-distance brain connections can target discrete pools of stem cells in their niche and stimulate them to divide and produce specific subtypes of olfactory bulb neurons. This allows the "on-demand" generation of particular types of neurons in the adult brain.
June 16, 2017
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Lund University stem cell researcher awarded Fernstrom prize for study on repairing damaged brain
Is it possible to convert a patient's own skin cells into functioning nerve cells? Or insert healthy genes to reprogram the cells of a damaged brain? Stem cell researcher Malin Parmar at Lund University in Sweden is studying these types of issues, in close collaboration with clinical researchers. She is now awarded a prize of SEK 100 000 from the Eric K. Fernstr÷m Foundation for her work.
September 21, 2016
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Misc. - M

Magnetic stem cells for gene engineering
Scientists from the Tomsk Polytechnic University's Laboratory of Novel Dosage are developing a technology to control mesenchymal stem cells of patients.
December 28, 2016
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Mapping pluripotency differences between mice, monkeys, and humans
New research shows that certain primate stem cells have pluripotency superior to some types derived from mice. the study maps how pluripotency differs among mice, monkeys, and humans, and illustrates for the first time the characteristics unique to primate stem cells.
August 25, 2016
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Mature heart muscle cells created in the laboratory from stem cells
Achievement believed to be a 'first'
January 26, 2017
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Mechanism identified through which lead may harm neural cells, children's neurodevelopment
Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children.
August 26, 2016
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Mechanism revealed for side effects of drug used in hematopoietic stem cell harvesting
Scientists have revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH). this is an important method for hematopoietic stem cell transplantation (HSCT) used to treat hematological malignancies such as leukemia.
November 24, 2016
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Mice study shows stem cell infusion could help treat glaucoma
An infusion of stem cells could help restore proper drainage for fluid-clogged eyes at risk for glaucoma. That's the upshot of a study led by a Veterans Affairs and University of Iowa team.
July 26, 2016
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Mini brains from the petri dish
A new method could push research into developmental brain disorders an important step forward. this is shown by a recent study in which the researchers investigated the development of a rare congenital brain defect. to do so, they converted skin cells from patients into so called induced pluripotent stem cells. from these 'jack-of-all-trades' cells, they generated brain organoids -- small three-dimensional tissues which resemble the structure and organization of the developing human brain.
April 4, 2017
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Mitochondria control stem cell fate
If the powerhouse of the cell, mitochondria, is disrupted, stem cells in the gut suffer, researchers have discovered. the human intestinal system covers an area of approximately 300 to 500 square meters due to its many protrusions (villi).
October 27, 2016
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Mitochondria regulates stem cell proliferation in gut epithelium, study shows
What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich (TUM) addressed this question by generating a new model system. Functioning mitochondria play a decisive role in cellular homeostasis, but what happens when an important player of the anti-stress program in mitochondria is switched off? on the one hand, this leads to the loss of stem cells, but on the other, it sets healing processes in motion.
October 27, 2016
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Mouse teeth providing new insights into tissue regeneration
Basic research has implications from lab-grown teeth to cancer research
April 27, 2017
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MRI guidance shows promise in delivering stem cell therapies
Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.
September 14, 2016
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Misc. - N

Nanofiber scaffolds demonstrate new features in the behaviour of stem and cancer cells
Novel scaffolds are shown enabling cells to behave in a different but controlled way in vitro due to the presence of aligned, self-assembled ceramic nanofibers of an ultra-high anisotropy ratio augmented into graphene shells.
August 23, 2016
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Neurobiologists use skin stem cells to generate new microglia
Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.
April 25, 2017
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New biomaterial allows scientists to study how stem cells sense stiffness of surrounding environment
A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania.
August 26, 2016
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New Cell Culture Gels Reveal Molecules that Promote Stem Cell Differentiation
Researchers studying stem cell differentiation on gels that imitate the nanofibrous structure and stiffness of biological tissue have discovered the specific molecules that stem cells use when selecting bone and cartilage fates.
July 28, 2016
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New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells
A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program.
November 22, 2016
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New findings about stem cells in the brain of patients with epilepsy
Neural stem cells have been found in epileptic brain tissue–outside the regions of the brain where they normally reside. In a group of patients who underwent surgery for epilepsy, over half had stem cells where healthy individuals do not have them, according to a study.
December 14, 2016
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New gene edited, fluorescently tagged human stem cell lines released
The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity. Distributed through the Coriell Institute for Medical Research, these powerful tools are a crucial first step toward visualizing the dynamic organization of cells to better understand what makes human cells healthy and what goes wrong in disease.
November 30, 2016
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New grant for injectable stem-cell carrying microspheres to regenerate bones
The University of Nottingham has secured £1.2m to develop injectable stem cell-carrying materials to treat and prevent fractures caused by osteoporosis and other bone-thinning diseases.
July 25, 2016
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New insights into mechanisms regulating gene expression in embryonic stem cells
Researchers have discovered new information about the mechanisms which maintain gene activity in human embryonic stem cells. The observed mechanism is essential for the self-renewal of stem cells.
May 31, 2017
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New Nanofiber Matrix to Help Produce Improved Quality Stem Cells for Disease Treatment
Culturing a large number of healthy human stem cells may soon be possible using a matrix composed of gelatin nanofibers on a synthetic polymer microfiber mesh.
February 15, 2017
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New platform for culturing stem cells
A powerful new tool combines micro- and nanotechnologies to precisely control stem cell culturing environment, report scientists.
March 14, 2017
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New platform for culturing stem cells
A team of researchers in Japan has developed a new platform for culturing human pluripotent stem cells that provides far more control of culture conditions than previous tools by using micro and nanotechnologies.
March 14, 2017
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New research shows promise for the production of patient-matched blood cells for therapies, disease modeling and drug screening
An elegant system to derive blood cell precursors from human pluripotent stem cells (hPSC) has now been developed by researchers. this type of stem cell has the potential to develop into many different kinds of cells in the body, and is capable of participating in organ repair and function.
March 19, 2017
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New stem cell delivery approach regenerates dental pulp-like tissue in a rodent model
Delivery of stem cells to damaged tooth roots using a collagen-derived biomaterial is effective at regenerating dental pulp-like tissue and shows promise as a potential therapy for restoring natural tooth function in a rodent model.
December 19, 2016
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New stem cell method could lead to powerful treatments for skeletal system injuries
A recent study, affiliated with UNIST has developed a new method of repairing injured bone using stem cells from human bone marrow and a carbon material with photocatalytic properties, which could lead to powerful treatments for skeletal system injuries, such as fractures or periodontal disease.
January 23, 2017
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New study provides most comprehensive picture to date of head and neck cancer stem cells
Cancer stem cells resist therapy and are a major cause of relapse, long after the bulk of a tumor has been killed. a University of Colorado Cancer Center study published in the Journal of the National Cancer Institute provides the most comprehensive picture to date of head and neck cancer stem cells, identifying genetic pathways that cancer stem cells hijack to promote tumor growth and visualizing the process of "asymmetric division" that allows a stem cell to create tumor tissue cells while retaining its own stem-like profile.
September 15, 2016
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New technique generates human neural stem cells for tissue engineering, 3D brain models
Researchers have discovered a new technique for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications, including a three-dimensional model of the human brain, according to a new report.
September 13, 2016
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New type of nanocomposite for stem cell therapy
In a new study published in Advanced Functional Materials ("Multimodal Magnetic Nanoclusters for Gene Delivery, Directed Migration, and Tracking of Stem Cells"), an international research team developed versatile magnetic nanoclusters (MNCs) capable of simultaneous gene delivery, direction of cell migration, and cell tracking for stem cell research.
May 31, 2017
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New ultrasound technique is first to image inside live cells
Researchers have developed a breakthrough technique that uses sound rather than light to see inside live cells, with potential application in stem-cell transplants and cancer diagnosis.
December 21, 2016
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Newly developed computer models can simulate stem cell transplant recovery
Scientists at Virginia Commonwealth University have developed computer models that can simulate the recovery of the immune system in patients undergoing stem cell transplants. In two recent studies, they reinforce the potential of using DNA sequencing and computer modeling to predict which stem cell transplant recipients might suffer complications such as graft-versus-host-disease, a condition where the donor's immune system attacks the recipient's body.
March 18, 2016
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Newly discovered breast stem cells wake up when exposed to ovarian hormones
Walter and Eliza Hall Institute researchers have used advanced cellular, bioinformatics and imaging technology to reveal a long-lived type of stem cell in the breast that is responsible for the growth of the mammary glands during pregnancy.
February 13, 2017
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NHLBI stem cell consortium provides new insights into genetics of heart disease, other conditions
Largest, most diverse collection of stem cells of its kind could lead to improved diagnoses, treatments.
April 6, 2017
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Nijmegen breakage syndrome: Molecular pathways that lead to microcephaly
Scientists have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.
September 8, 2016
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NIH-funded study helps explain how zebrafish recover from blinding injuries
Decrease in neurotransmitter GABA triggers stem cell production in the retina.
March 9, 2017
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Novel label-free microscopy enables dynamic, high-resolution imaging of cell interactions
Researchers from the University of Illinois at Urbana-Champaign have invented a novel live-cell imaging method that could someday help biologists better understand how stem cells transform into specialized cells and how diseases like cancer spread. the Photonic Crystal Enhanced Microscope (PCEM) is capable of monitoring and quantitatively measuring cell adhesion, a critical process involved cell migration, cell differentiation, cell division, and cell death.
December 6, 2016
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Novel scaffolds may open new avenues in stem and cancer cell manipulation
A discovery in the field of biomaterials may open new frontiers in stem and cancer cell manipulation and associated advanced therapy development. Novel scaffolds are shown enabling cells to behave in a different but controlled way in vitro due to the presence of aligned, self-assembled ceramic nanofibers of an ultra-high anisotropy ratio augmented into graphene shells.
August 23, 2016
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Novel tool confers targeted, stable editing of epigenome in human stem cells
Salk Institute scientists have developed a novel technology to correct disease-causing aberrations in the chemical tags on DNA that affect how genes are expressed. These types of chemical modifications, collectively referred to as epigenetics or the epigenome, are increasingly being considered as important as the genomic sequence itself in development and disease.
May 5, 2017
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Misc. - O

Obesity reprograms muscle stem cells
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research.
February 22, 2017
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Old gut stem cells made to grow like young ones in a dish
Intestines experience a lot of wear and tear. Without the stalwart stem cells that live in our gut's lining, our ability to absorb food would dwindle and bacteria from the digestive tract would be able to breach the bloodstream. Unfortunately, the regenerative abilities of intestinal stem cells decline with age. However, it may be possible to partially reverse aging in gut stem cells, at least in a petri dish.
March 14, 2017
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Ovarian hormones awaken newly discovered breast stem cells
Researchers have used advanced cellular, bioinformatics and imaging technology to reveal a long-lived type of stem cell in the breast that is responsible for the growth of the mammary glands during pregnancy.
February 13, 2017
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Misc. - P

Parsley and other plants lend form to human stem cell scaffolds
Scientists are using the decellularized husks of plants such as parsley, vanilla and orchids to form three-dimensional scaffolds that can then be primed and seeded with human stem cells to optimize their growth in the lab dish and, ultimately, create novel biomedical implants.
March 21, 2017
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Penn researchers uncover strategy to reverse effects of dyskeratosis congenita
Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. Typically diagnosed in childhood, the disorder causes stem cells to fail, leading to significant problems including bone marrow failure, lung fibrosis, dyskeratosis of the skin and intestinal atrophy and inflammation. Patients are also at heightened risk of several types of cancer.
August 18, 2016
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Possible treatment targets found for pre-malignant bone marrow disorders
Nature Immunology study uncovers key driver of MDS in blood stem cells
December 29, 2016
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Potential drugs and targets for brain repair
Researchers have discovered drugs that activate signaling pathways leading to specific adult brain cell types from stem cells in the mouse brain, according to a new study. the results may open new avenues for drug development aimed at treatment of degenerative brain disorders.
March 28, 2017
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Potential of stem cell therapy to repair lung damage
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential implications for the future treatment of patients.
March 27, 2017
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Protein found to bolster growth of damaged muscle tissue
Biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could contribute to treatments for muscle degeneration caused by old age or muscular dystrophy.
July 19, 2016
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Protein present on stem cell surface can boost growth of damaged muscle tissue
Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.
July 19, 2016
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Protein primes mouse stem cells to quickly repair injury, study finds
Like drag car racers revving their engines at the starting line, stem cells respond more quickly to injury when they've been previously primed with one dose of a single protein, according to a study.
April 18, 2017
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Misc. - R

Real-time MRI guidance could help target and deliver stem cell therapies
Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.
September 14, 2016
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Reprogrammable skin stem cells in a test-tube
To develop new treatments for skin cancer, drugs need to be tested on animals. now scientists from the Max Planck Institute for Biology of Ageing in Cologne have been able to grow mouse skin stem cells in a dish (EMBO, "Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and progeny."). These stem cells in a test-tube could reduce the number of animal experiments.
December 19, 2016
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Research yields first successful isolation, maintenance of haploid embryonic stem cells in humans
Stem cell research holds huge potential for medicine and human health. In particular, human embryonic stem cells (ESCs), with their ability to turn into any cell in the human body, are essential to the future prevention and treatment of disease.
June 29, 2017
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Researchers decipher how the body controls stem cells
Stem cells are unspecialized cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will differentiate, for example, into a blood, liver or nerve cell. Researchers have now identified an ingenious mechanism by which the body orchestrates the regeneration of red and white blood cells from progenitor cells.
March 15, 2017
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Researchers develop first non-human primate X-SCID models using genome editing techniques
Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. the findings were published in Cell Stem Cell, July 2016.
January 3, 2017
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Researchers develop new platform for culturing pluripotent stem cells
A team of researchers in Japan has developed a new platform for culturing human pluripotent stem cells that provides far more control of culture conditions than previous tools by using micro and nanotechnologies.
March 14, 2017
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Researchers develop new strategy to limit side effects of stem cell transplants
A new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants has now been developed by scientists.
August 15, 2016
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Researchers develop synthetic cardiac stem cells that offer therapeutic benefits
Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and First Affiliated Hospital of Zhengzhou University have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies.
December 25, 2016
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Researchers discover BRCA1 gene is key for blood forming stem cells
Researchers have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia. the stem cells die before they have an opportunity to transform into a blood cancer.
January 24, 2017
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Researchers discover intestinal quiescent stem cells that are resistant to chemotherapy
The intestine has a high rate of cellular regeneration due to the wear and tear originated by its function degrading and absorbing nutrients and eliminating waste. the entire cell wall is renewed once a week approximately. this explains why the intestine holds a large number of stem cells in constant division, thereby producing new cell populations of the various types present in this organ.
March 10, 2017
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Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells
Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children. the study, from Harvard T.H. Chan School of Public Health, suggests that lead exposure can lead to oxidative stress -- a process that can change cell behavior and has been linked with health problems -- among certain proteins within neural stem cells.
August 26, 2016
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Researchers find new way to prevent graft-versus-host disease after stem cell transplants
Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of Diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.
April 18, 2017
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Researchers reveal mechanism for side effects of drug used for treating hematological malignancies
A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH). this is an important method for hematopoietic stem cell transplantation (HSCT) used to treat hematological malignancies such as leukemia.
November 24, 2016
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Researchers take broad look at stem cells
Scientists have focused recent work on the study of and utility of adult-derived stem cells. the team put together the review after recognizing that the medical and general communities have limited knowledge about the various types of stem cells and how they could be used in medicine.
February 22, 2017
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Researchers turn urine into research tools
Breakthrough non-invasive technique generates stem cells to study Down syndrome
March 28, 2017
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Researchers uncover how molecular switches control gene activity in human embryonic stem cells
Researchers at the Babraham Institute have revealed a new understanding of the molecular switches that control gene activity in human embryonic stem cells. this insight provides new avenues for improving the efficiency of being able to drive stem cells to create a desired cell type - an essential requirement to fulfil their promise in regenerative medicine.
December 6, 2016
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Researchers unravel mechanism by which hippocampal stem cells regulate their own fate
To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in. a research group at the University of Basel now describes for the first time a mechanism by which hippocampal neural stem cells regulate their own cell fate via the protein Drosha.
August 18, 2016
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Researchers use graphene, electricity to change stem cells for nerve regrowth
Researchers looking for ways to regenerate nerves can have a hard time obtaining key tools of their trade.
April 10, 2017
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Researchers use stem cells to model different genetic scenarios that underlie neurologic disease
Researchers at Case Western Reserve University School of Medicine have successfully grown stem cells from children with a devastating neurological disease to help explain how different genetic backgrounds can cause common symptoms. the work sheds light on how certain brain disorders develop, and provides a framework for developing and testing new therapeutics. Medications that appear promising when exposed to the new cells could be precisely tailored to individual patients based on their genetic background.
March 30, 2017
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Misc. - S

Salk scientist receives NIH Pioneer Award to support innovative biomedical research
Salk Professor Juan Carlos Izpisua Belmonte has been awarded a 2016 National Institutes of Health Pioneer Award, a highly coveted grant that supports the most innovative biomedical research, for his work in stem cell biology and regeneration.
October 18, 2016
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San Antonio scientists aim to develop effective method for stem cell delivery to the brain
A national science publication has featured the work of San Antonio scientists aiming to develop a more effective method for delivering neural stem cells to the brain in an effort to move forward stem cell therapies to treat neurological disorders.
October 18, 2016
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Scaffolds Covered in Stem Cells and Silver Ions to Prevent Osteomyelitis
Bone infections are often very difficult to treat, and with the rise of MRSA this issue has become only more challenging. a team of researchers from University of Missouri, University of North Carolina at Chapel Hill and North Carolina State University, and Silpakorn University in Thailand has developed a way of making tissue scaffolds that ward off MRSA while promoting natural healing at the site of their implantation.
February 24, 2017
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Scientists Brew Up the Creepiest Batches of Brain Balls Yet
Stem cell biologists are basically modern day witches. While they're not exactly taking a creepy fetal Lord Voldemort and turning him into noseless Ralph Fiennes, these scientists can use tinctures and concoctions to grow incredible things from just a few human skin cells.
April 26, 2017
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Scientists create artificial mouse 'embryo' from stem cells for first time
Scientists have managed to create a structure resembling a mouse embryo in culture, using two types of stem cells -- the body's 'master cells' -- and a 3-D scaffold on which they can grow.
March 2, 2017
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Scientists Create Part-Human, Part-Pig Embryo
One goal of this stem cell research is to create organs for transplant
January 26, 2017
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Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs
Scientists at the Institute for Infectious Diseases, University of Bern have developed an in vitro stem cell-based bioassay grown on multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins. Their assay could serve in minimizing animal experiments as well as provide a physiological relevant platform for drug-screening of neuroactive compounds.
February 28, 2017
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Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers
Researchers at the Johns Hopkins Kimmel Cancer Center say they have developed a system that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other cancers.
August 02, 2016
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Scientists developing magnetic stem cells to fight cancer
Scientists from the Tomsk Polytechnic University's Laboratory of Novel Dosage are developing a technology to control mesenchymal stem cells of patients. the technology will allow treating cancer more effective. to fight cancer cells the scientists suggest using the patient's own magnet controlled cells. Native body cells won't be rejected by its immune system and can deliver medication directly into the center of the disease.
December 29, 2016
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Scientists developing MRI-guided neural stem cell delivery method
Scientists are aiming to develop a more effective method for delivering neural stem cells to the brain in an effort to move forward stem cell therapies to treat neurological disorders.
October 18, 2016
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Scientists discover an unexpected influence on dividing stem cells' fate
When it divides, a stem cell has a choice: produce more stem cells or turn into the specific types of cells that compose skin, muscle, brain, or other tissue. new experiments in skin show this decision can be altered if tiny organs within cells aren't positioned and divvied up properly.
February 10, 2017
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Scientists discover key molecule that drives regeneration in planarian stem cells
Many living creatures possess exceptional abilities that set them apart from other species. Cheetahs can run up to 60 miles per hour; ants can lift 100 times their body weight; flatworms can regrow amputated body parts. Scientists have spent decades studying the mechanisms that drive such remarkable feats, with the hopes that any secrets they uncover might lead to new perspectives in human biology and new ways to enhance health and ameliorate disease.
August 12, 2016
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Scientists generate functional tissue-engineered liver from adult stem and progenitor cells
A research team led by investigators at the Saban Research Institute of Children's Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver (TELi) was found to contain normal structural components such as hepatocytes, bile ducts and blood vessels.
August 31, 2016
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Scientists grow and purify earliest lung progenitors from human stem cells
Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells. But in a matter of months, the cells get organized. they gather together, branch and bud, some forming airways and others alveoli, the delicate sacs where our bodies exchange oxygen for carbon dioxide. the end result, ideally: two healthy, breathing lungs.
May 3, 2017
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Scientists grow mini human brains
Scientists in Singapore have made a big leap on research on the 'mini-brain'. These advanced mini versions of the human midbrain will help researchers develop treatments and conduct other studies into Parkinson's Disease and ageing-related brain diseases.
July 29, 2016
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Scientists Have Created the First Artificial Embryo Without Using an Egg or Sperm
Using stem cells in grown-on 3D scaffolding in a laboratory petri dish, scientists have for the first time created an embryo made entirely from stem cells.
March 7, 2017
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Scientists identify new gene that prompts muscle stem cells to fuse together
A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1 by Nature Communications reports scientists identify a new gene essential to this process, shedding new light on possible new therapeutic strategies.
June 1, 2017
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Scientists make major advance in understanding how stem cells become specialized
Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have made a major advance in understanding how the cells of an organism, which all contain the same genetic information, come to be so diverse. a study published today in Molecular Cell shows that a protein called OCT4 narrows down the range of cell types that stem cells can become.
August 05, 2016
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Scientists map reorganization of genetic material in cells using 3-D imaging technique
Scientists have mapped the reorganization of genetic material that takes place when a stem cell matures into a nerve cell. Detailed 3-D visualizations show an unexpected connectivity in the genetic material in a cell's nucleus, and provide a new understanding of a cell's evolving architecture.
November 17, 2016
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Scientists tissue engineer functional part of human stomach in laboratory
Researchers can grow functional stomach and intestinal tissues to study diseases, new drugs
January 4, 2017
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Scientists tissue engineer human intestines and functioning nerves
Scientists report using human pluripotent stem cells to grow human intestinal tissues that have functioning nerves in a laboratory, and then using these to recreate and study a severe intestinal nerve disorder called Hirschsprung's disease.
November 21, 2016
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Scientists tissue engineer human intestines and functioning nerves
Scientists report in Nature Medicine using human pluripotent stem cells to grow human intestinal tissues that have functioning nerves in a laboratory, and then using these to recreate and study a severe intestinal nerve disorder called Hirschsprung's disease.
November 21, 2016
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Scientists turn human induced pluripotent stem cells into lung cells
'Bronchospheres' may pave way for personalized cystic fibrosis treatments
May 3, 2017
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Scientists unveil the UK's largest resource of human stem cells from healthy donors
Powerful resource created for scientists studying human development and disease
May 11, 2017
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Scientists use stem cells to create human/pig chimera embryos
Efforts by researchers to grow the first embryos containing cells from humans and pigs proved more challenging than anticipated, they report in a new study. Human/animal chimeras can offer insights into early human development and disease onset and provide a realistic drug-testing platform. they may also someday provide a means of growing human cells, tissues, and organs for regenerative medicine. for now, however, they are helping scientists understand how human stem cells grow and specialize.
January 26, 2017
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Scientists wage fight against aging bone marrow stem cell niche
Study suggests restoring body's blood factory to boost immunity, fend off cancers
March 2, 2017
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Senescent cells drive plaque formation in animal models of atherosclerosis, research shows
Atherosclerosis is a disease in which arteries narrow due to plaques. that narrowing can lead to heart attacks and strokes -- both of which are leading causes of death in the U.S. Now, in a paper published in Science, Mayo Clinic researchers and colleagues show that senescent cells drive plaque formation in animal models of atherosclerosis.
October 27, 2016
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Sharing of patients' stem cells could boost bipolar disorder research
Stem cells from patients with bipolar disorder are being made available to scientists around the world to boost research into the condition.
August 09, 2016
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Single gene encourages growth of intestinal stem cells, supporting 'niche' cells, and cancer
Finding in mice could lead to new therapies for damaged organs, cancer
April 28, 2017
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Skin stem cells used to generate new brain cells
Using human skin cells, University of California, Irvine neurobiologists and their colleagues have created a method to generate one of the principle cell types of the brain called microglia, which play a key role in preserving the function of neural networks and responding to injury and disease.
April 25, 2017
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SkinGun Investigational Therapy for Burns Uses Patients' Own Stem Cells for Healing
RenovaCare, a company based in New York City, is seeking FDA approval for the SkinGun, a device to treat burns using a patient's own stem cells. Significant portions of skin can be destroyed in burn injuries, meaning that regenerative therapy is required to restore or replace the injured tissue.
February 2, 2017
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Stem cell 'living bandage' for knee injuries trialed in humans
A 'living bandage' made from stem cells, which could revolutionize the treatment and prognosis of a common sporting knee injury, has been trialed in humans for the first time.
December 16, 2016
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Stem cell gene found to command skeletal muscle regeneration
Prox1 gene has long been known to play an important role in fetal development. Researchers have now discovered that Prox1 is essential also for skeletal muscle stem cell differentiation. Skeletal muscles are important not only for locomotion but also for the regulation of whole-body metabolism. Muscles have remarkable capacity to regenerate after injury and to adapt in response to exercise training.
October 12, 2016
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Stem cell secretions may protect against glaucoma
Scientists find that stem cell exosomes promote survival of retinal ganglion cells in rats
January 27, 2017
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Stem cell secretions may protect against glaucoma
NEI scientists find that stem cell exosomes promote survival of retinal ganglion cells in rats.
January 27, 2017
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Stem Cell Therapy for Autism Shows Promise
A stem cell treatment for autism shows promise, according to a new study, but the investigators and other experts emphasize that the therapy is still in the early stages and much more research is needed.
April 6, 2017
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Stem cell therapy heals injured mouse brain
Animal study examines method for restoring brain cells killed by stroke or other neurological diseases.
August 22, 2016
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Stem cell therapy is safe for stroke patients, study shows
May aid recovery if given early
March 19, 2017
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Stem cell therapy may harm heart disease patients, study finds
Patients with severe and end-stage heart failure have few treatment options available to them apart from transplants and "miraculous" stem cell therapy. But a new Tel Aviv University study finds that stem cell therapy may, in fact, harm heart disease patients.
June 15, 2017
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Stem cell therapy restores normal bone structure in mice with age-related osteoporosis
Imagine telling a patient suffering from age-related (type-II) osteoporosis that a single injection of stem cells could restore their normal bone structure. this week, with a publication in STEM CELLS Translational Medicine, a group of researchers from the University of Toronto and the Ottawa Hospital suggest that this scenario may not be too far away.
March 18, 2016
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Stem cell therapy reverses blindness in animals with end-stage retinal degeneration
A stem cell-based transplantation approach that restores vision in blind mice moves closer to being tested in patients with end-stage retinal degeneration, according to a study. the researchers showed that retinal tissue derived from mouse induced pluripotent stem cells (iPSCs) established connections with neighboring cells and responded to light stimulation after transplantation into the host retina, restoring visual function in half of mice with end-stage retinal degeneration.
January 10, 2017
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Stem cell transplants may induce long-term remission of multiple sclerosis
Encouraging results help set stage for larger studies.
February 1, 2017
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Stem cell treatment helps improve motor functions, nervous system conditions in mice with ALS
Researchers at the University of South Florida show in a new study that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier.
May 15, 2017
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Stem cell-based cartilage could fix your broken hip
The living joint can even release anti-inflammatory molecules.
July 21, 2016
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Stem cells also rust
Oxygen in the air is well known to cause damaging rust on cars through a process known as oxidation. Similarly, a research group has now identified that certain cells during embryonic development also are negatively affected by oxidation. this oxidation is capable of leading to a block in cellular function.
October 22, 2016
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Stem cells collected from fat may have use in anti-aging treatments
Study shows cells are more stable than previously thought
February 17, 2017
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Stem cells collected from fat more stable than previously thought, Penn study shows
Adult stem cells collected directly from human fat are more stable than other cells - such as fibroblasts from the skin - and have the potential for use in anti-aging treatments, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. they made the discovery after developing a new model to study chronological aging of these cells.
February 17, 2017
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Stem cells contribute to origin of cancer in different organs of mice
The idea that stem cells - special cells that divide to repair and generate tissues - might be the major determinant of cancer risk has provoked great debate in the scientific community. some researchers maintain that environmental carcinogens are more important in defining cancer risk. now researchers at St. Jude Children's Research Hospital and the University of Cambridge, England, have confirmed the crucial contribution of stem cells to the origins of cancer in different organs of mice. the results appear online today in the journal Cell.
August 25, 2016
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Stem Cells for Knees: Promising Treatment or Hoax?
At 55, George Chung of Los Angeles could keep up with skiers decades younger, taking on difficult slopes for hours and hours. "Skiing was my passion," he says.
April 14, 2017
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Stem cells from jaw bone help repair damaged cartilage
Columbia College of Dental Medicine researchers have identified stem cells that can make new cartilage and repair damaged joints.
October 10, 2016
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Stem cells grown into 3-D lung-in-a-dish
By coating tiny gel beads with lung-derived stem cells and then allowing them to self-assemble into the shapes of the air sacs found in human lungs, researchers have succeeded in creating three-dimensional lung "organoids." the laboratory-grown lung-like tissue can be used to study diseases including idiopathic pulmonary fibrosis, which has traditionally been difficult to study using conventional methods.
September 15, 2016
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Stem cells help researchers identify neuronal defects causing Angelman syndrome
Researchers have used stem cells derived from patients with Angelman syndrome to identify the underlying neuronal defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure.
April 24, 2017
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Stem cells in plants and animals behave surprisingly similarly
A new study shows that the behavior of stem cells in plants and animals is surprisingly similar. the researchers were able to produce mathematical equations that reveal very small differences in the behavior of the proteins. the results can hopefully be used in stem cell research involving humans.
May 12, 2017
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Stem cells may be the key to staying strong in old age
A new study, performed in mice, could lead to new approaches to help people stay stronger in old age. The study challenges conventional wisdom with results suggesting that loss of muscle stem cells is the main driving force behind muscle decline in old age.
June 6, 2017
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Stem cells may significantly improve tendon healing by regulating inflammation
New research suggests the potential of tendon stem cells to improve healing and treatment for acute tendon injuries and chronic tendon disease
May 23, 2017
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Stem cells shown to restore erection capability in men with erectile dysfunction
New clinical trial results show that stem cells can restore sufficient erectile function to allow previously impotent men to have spontaneous intercourse. this is the first time stem cell therapy has produced patients who have recovered sufficient erectile function to enable intercourse. this is an early trial, which was primarily addressing safety and dosage (a Phase 1 trial), so the results need to be interpreted accordingly.
March 27, 2017
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Stem cells yield nature's blueprint for body's vasculature
The developmental pathway that gives rise to the different types of cells that make up human vasculature has now been identified by a team of researchers.
May 30, 2017
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Study describes method to engineer brown adipose tissue from white fat-derived stem cells
Researchers have demonstrated the potential to engineer brown adipose tissue, which has therapeutic promise to treat metabolic diseases such as obesity and type 2 diabetes, from white adipose-derived stem cells (ASCs).
March 3, 2017
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Study in mice suggests stem cells could ward off glaucoma
Treatment would use cells harvested from patient's skin
July 26, 2016
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Sub-set of stem cells found to minimize risks when used to treat damaged hearts
Scientists use mathematical modeling to simulate human mesenchymal stem cell delivery to a damaged heart and found that using one sub-set of these stem cells minimizes the risks associated with this therapy. the study represents a development in novel strategies to repair and regenerate heart muscle and could improve stem cell treatments for heart attack patients.
July 25, 2016
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Misc. - T

Taking the sting out of bone repair
Spherical biodegradable carriers support scalable and cost-effective stem cell expansion and bone formation for tissue engineering.
April 18, 2017
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Targeting cancer stem cells improves treatment effectiveness, prevents metastasis
Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma -- the most common head and neck cancer and the second-most common skin cancer, according to a new study. Head and neck squamous cell carcinoma is a highly invasive form of cancer and frequently spreads to the cervical lymph nodes.
March 10, 2017
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The Goldilocks effect in aging research
For stem cells to be healthy, telomere length has to be just right, scientists have found. the finding deepens our understanding of stem cell biology and could help advance stem cell-based therapies, especially related to aging and regenerative medicine.
December 6, 2016
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The intestine has a reservoir of stem cells that are resistant to chemotherapy
These comprise a small group of passive stem cells -quiescent- that are activated when needed and have the capacity to produce any kind of intestinal cell. Quiescent cells are relevant for tissue regeneration and for participation in tumor development
March 9, 2017
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The origin of stem cells
The protein WOX2 is responsible for enabling plants to develop organs throughout their lives.
February 8, 2017
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Therapy response in brain tumor cells is linked to disease prognosis
The brain tumor form glioblastoma is difficult to treat and has very poor prognosis. In a new study, scientists show that a type of stem cell in the tumor is present in different states, with different response to drugs and radiation. the results may open an avenue towards development of new treatment strategies designed to reverse therapy resistant cell states to more sensitive states.
December 13, 2016
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Three blinded after dubious stem cell treatment injected into their eyeballs
Patients signed up after seeing clinical trial on govt. site, but didn't enter a trial.
March 16, 2017
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Time-lapse video reveals cells essential for 'birth' of blood stem cells
A new study examines origin of blood stem cells during development and offers clues for making "donor blood" in the laboratory for therapeutic use.
April 10, 2017
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Transcription factor Nanog plays key role in reproduction of embryonic stem cells
The transcription factor Nanog plays a crucial role in the self-renewal of embryonic stem cells. Previously unclear was how its protein abundance is regulated in the cells. Researchers at the Helmholtz Zentrum Munchen and the Technical University of Munich, working in collaboration with colleagues from ETH Zurich, now report in 'Cell Systems' that the more Nanog there is on hand, the less reproduction there is.
November 24, 2016
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Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats
In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with Diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.
August 30, 2016
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Transplanted stem cells become eggs in sterile mice
Oocyte success raises hopes for infertility treatments
May 18, 2017
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Treating heart failure with muscle stem cell patch
A new study tests a groundbreaking approach to treating heart failure. Using the patients' own muscle stem cells, the researchers successfully patched up damaged hearts, yielding encouraging results.
April 6, 2017
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Tuned gels reveal molecules that drive stem cell differentiation
By monitoring stem cell differentiation on gels that mimic the stiffness of biological tissue, researchers have identified the metabolites that stem cells use when selecting bone and cartilage fates. When fed to standard stem cell cultures, these molecules were then found to guide stem cells to generate desired cell types.
July 27, 2016
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Two proteins safeguard skin stem cells
Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. now a research team has identified two proteins that are fundamental to conserve skin stem cells and has shown that without these proteins these cells are lost.
July 28, 2016
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Two-part system turns stem cells into whatever you want
Whether using embryonic or adult stem cells, coercing these master cells to convert to the desired target cell and reproduce flawlessly is difficult. Now an international team of researchers has a two-part system that can convert the cells to the targets and then remove the remnants of that conversion, leaving only the desired DNA behind to duplicate.
June 5, 2017
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Misc. - U

UCLA study shows how the brain initiates repair by generating replacement cells after stroke
UCLA researchers have shown that the brain can be repaired – and brain function can be recovered – after a stroke in animals. the discovery could have important implications for treating a mind-robbing condition known as a white matter stroke, a major cause of dementia.
December 21, 2016
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Unique stem cells as a potential asthma treatment
A new therapy developed through stem cell technology holds promise as a treatment for chronic asthma.
June 28, 2017
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US alters rules for funding for animals with human stem cells
Trying to avoid animals with humanized brains or reproductive tissues.
August 05, 2016
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Using stem cells to boost immunity against Candida albicans infections
A biological mechanism has been revealed by researchers that generates cells that are better equipped to fight off serious infections caused by the Candida albicans fungus.
October 26, 2016
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Misc. - V

Vitamin a deficiency is detrimental to blood stem cells
Lack of vitamin a in the body has a detrimental effect on the hematopoietic system in the bone marrow. the deficiency causes a loss of important blood stem cells, scientists now report. These findings will open up new prospects in cancer therapy.
May 5, 2017
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Misc. - W

Watching fat-derived stem cells transform offers clues to combating osteoporosis in older women
For years, scientists have studied how stem cells might be used to treat many diseases, including osteoporosis. One consistent challenge has been observing and monitoring the process through which stem cells transform. Now, using an established scientific method, University of Missouri researchers are able to watch how human fat cells transform into bone tissue cells; in the process the research team has uncovered information about osteoporosis in older women.
October 5, 2016
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Watching stem cells change provides clues to fighting osteoporosis in older women
For years, scientists have studied how stem cells might be used to treat many diseases, including osteoporosis. One consistent challenge has been observing and monitoring the process through which stem cells transform. Now, using an established scientific method, researchers are able to watch how human fat cells transform into bone tissue cells; in the process the research team has uncovered information about osteoporosis in older women.
October 5, 2016
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What is hematopoietic stem cell transplantation?
Hematopoietic stem cell transplantation was first used as a treatment for some types of cancer but is now widely used as a therapy for various autoimmune diseases.
June 26, 2017
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With stem cells to new intervertebral discs
It is the "shock absorber' between the vertebrae of the spine, cushioning every step, bend and jump: the intervertebral disc. If the fibrocartilage tissue in the spine degenerates over time, an intervertebral disc can "slip' -- pinching the medulla or nerves. the consequences include intense pain or even paralysis. not only people, but also dogs are often susceptible to this disease.
May 9, 2017
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